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The map label for this gene is secY

Identifier: 52783991

GI number: 52783991

Start: 142441

End: 143736

Strand: Direct

Name: secY

Synonym: BLi00153

Alternate gene names: 52783991

Gene position: 142441-143736 (Clockwise)

Preceding gene: 52783990

Following gene: 52783992

Centisome position: 3.37

GC content: 44.21

Gene sequence:

>1296_bases
TTGTTTAAGACAATCTCCAATTTTATGCGTGTGAAGGATATTCGGAATAAGATTATCTTCACTCTTTTAATGCTTATCGT
CTTTCGTCTCGGTTCGTTCATTCCTGTGCCGCACGTAAACACAGAAGTTTTAAAGGCACAGGATCAAATGAGCGTATTTG
GGATTCTAAACACATTTGGCGGCGGTGCATTGTTCAACTTCTCCATTCTTGCGATGGGAATCATGCCTTACATCACAGCT
TCTATCATCATCCAGCTCCTGCAGATGGATGTTGTGCCGAAGTTTACCGAATGGTCTAAGCAGGGGGAAGTTGGTCGCCG
AAAACTAGCTCAGTTCACAAGGTACTTCACGATCGTTCTTGGATTTATCCAGGCTTTAGGTATGTCTTACGGGTTTAACA
ACATGGCCGGCGGCGCGTTGATTACAGACCCGGGAGTCGGTACTTATTTGCTTATTGCGATTGTACTAACTGCTGGAACT
GCTTTTTTAATGTGGCTGGGAGAACAAATTACGTCTCATGGAGTTGGTAACGGAATATCCATTATCATCTTCGCCGGTAT
CGTTGCCGGTATTCCGCAGACGATTAATCAGATCTACGCTCAGCAGTTTGTAGATGCTGGAGATCAGTTATTCTTGCAAA
TCATAAAGGTTGTCGTTATATTGGTTGCGATTTTAGCGATTGTCGTTGGCGTTATTTTCATCCAACAGGCGGTTAGAAAA
ATCTCAATTCAATATGCGAAAGGTTCAGGCCGTTCACCGGTTCCTGGCGGCCAGTCTACACACTTGCCGCTGAAGGTTAA
CCCGGCGGGAGTTATTCCGGTTATCTTTGCCGTAGCATTTATCACCACTCCGCGGACCGTGGCAACATTCTTTGGCTCCA
ATGACGTCACGAATTGGATTCAAAAAACGTTTGATTACACGCATCCGGTCGGAATGGGAGTTTATGCAGCATTGATCATC
GCCTTTACCTATTTCTATGCATTTGTGCAGGTTAACCCTGAGCAAATGGCCGATAATCTTAAAAAACAAGGTGGCTATAT
TCCGGGAGTTCGTCCAGGAAAAATGACTCAAGATAGAATTACGAGCATTTTGTATCGACTTACATTTGTAGGCTCCATAT
TCTTGGCCGTGATTGCCATTCTTCCTGTCTTGTTCGTTAATATTGCTGGGCTGCCTTCTTCTGCACAAATTGGTGGAACA
AGTTTGCTGATTGTCATCGGGGTTGCACTTGAAACAATGAAGCAGCTTGAAAGCCAGCTGGTAAAACGAAACTATCGTGG
ATTTATGAAGCACTAG

Upstream 100 bases:

>100_bases
GGTAAATTAGAAAAGAAATTAACTGTTAAAGCCAATAAATTCTCCGCTTCTGCTAAACAAGCAATTGAGGCTGCTGGCGG
TACAGCTGAGGTGATCTAAC

Downstream 100 bases:

>100_bases
AGGAAATGGGGCGCGCCCATTCCCTCTAAAATAGAGAGGACGGGGAATCCGAAATGAACTTAGTCTTAATGGGACTGCCT
GGAGCCGGTAAAGGGACACA

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MFKTISNFMRVKDIRNKIIFTLLMLIVFRLGSFIPVPHVNTEVLKAQDQMSVFGILNTFGGGALFNFSILAMGIMPYITA
SIIIQLLQMDVVPKFTEWSKQGEVGRRKLAQFTRYFTIVLGFIQALGMSYGFNNMAGGALITDPGVGTYLLIAIVLTAGT
AFLMWLGEQITSHGVGNGISIIIFAGIVAGIPQTINQIYAQQFVDAGDQLFLQIIKVVVILVAILAIVVGVIFIQQAVRK
ISIQYAKGSGRSPVPGGQSTHLPLKVNPAGVIPVIFAVAFITTPRTVATFFGSNDVTNWIQKTFDYTHPVGMGVYAALII
AFTYFYAFVQVNPEQMADNLKKQGGYIPGVRPGKMTQDRITSILYRLTFVGSIFLAVIAILPVLFVNIAGLPSSAQIGGT
SLLIVIGVALETMKQLESQLVKRNYRGFMKH

Sequences:

>Translated_431_residues
MFKTISNFMRVKDIRNKIIFTLLMLIVFRLGSFIPVPHVNTEVLKAQDQMSVFGILNTFGGGALFNFSILAMGIMPYITA
SIIIQLLQMDVVPKFTEWSKQGEVGRRKLAQFTRYFTIVLGFIQALGMSYGFNNMAGGALITDPGVGTYLLIAIVLTAGT
AFLMWLGEQITSHGVGNGISIIIFAGIVAGIPQTINQIYAQQFVDAGDQLFLQIIKVVVILVAILAIVVGVIFIQQAVRK
ISIQYAKGSGRSPVPGGQSTHLPLKVNPAGVIPVIFAVAFITTPRTVATFFGSNDVTNWIQKTFDYTHPVGMGVYAALII
AFTYFYAFVQVNPEQMADNLKKQGGYIPGVRPGKMTQDRITSILYRLTFVGSIFLAVIAILPVLFVNIAGLPSSAQIGGT
SLLIVIGVALETMKQLESQLVKRNYRGFMKH
>Mature_431_residues
MFKTISNFMRVKDIRNKIIFTLLMLIVFRLGSFIPVPHVNTEVLKAQDQMSVFGILNTFGGGALFNFSILAMGIMPYITA
SIIIQLLQMDVVPKFTEWSKQGEVGRRKLAQFTRYFTIVLGFIQALGMSYGFNNMAGGALITDPGVGTYLLIAIVLTAGT
AFLMWLGEQITSHGVGNGISIIIFAGIVAGIPQTINQIYAQQFVDAGDQLFLQIIKVVVILVAILAIVVGVIFIQQAVRK
ISIQYAKGSGRSPVPGGQSTHLPLKVNPAGVIPVIFAVAFITTPRTVATFFGSNDVTNWIQKTFDYTHPVGMGVYAALII
AFTYFYAFVQVNPEQMADNLKKQGGYIPGVRPGKMTQDRITSILYRLTFVGSIFLAVIAILPVLFVNIAGLPSSAQIGGT
SLLIVIGVALETMKQLESQLVKRNYRGFMKH

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family

Homologues:

Organism=Escherichia coli, GI1789696, Length=426, Percent_Identity=42.7230046948357, Blast_Score=289, Evalue=2e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECY_BACLD (Q05207)

Other databases:

- EMBL:   X70087
- EMBL:   AE017333
- EMBL:   CP000002
- PIR:   S30116
- RefSeq:   YP_077420.1
- RefSeq:   YP_089820.1
- ProteinModelPortal:   Q05207
- STRING:   Q05207
- EnsemblBacteria:   EBBACT00000055343
- EnsemblBacteria:   EBBACT00000059573
- GeneID:   3028224
- GeneID:   3100553
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi00153
- KEGG:   bli:BL01031
- NMPDR:   fig|279010.5.peg.1612
- eggNOG:   COG0201
- GeneTree:   EBGT00050000001422
- HOGENOM:   HBG565931
- OMA:   IQTYVIS
- ProtClustDB:   PRK09204
- BioCyc:   BLIC279010-1:BLI00153-MONOMER
- BioCyc:   BLIC279010:BL01031-MONOMER
- InterPro:   IPR002208
- InterPro:   IPR023201
- PANTHER:   PTHR10906
- PIRSF:   PIRSF004557
- PRINTS:   PR00303
- TIGRFAMs:   TIGR00967

Pfam domain/function: PF00344 SecY; SSF103491 SecY

EC number: NA

Molecular weight: Translated: 47031; Mature: 47031

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: PS00755 SECY_1; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xb55c8b4)-; HASH(0xcb99294)-; HASH(0xb67cec4)-; HASH(0xc2735cc)-; HASH(0xabe58ec)-; HASH(0xabe368c)-; HASH(0xc265390)-; HASH(0xc2735c0)-; HASH(0xad97484)-; HASH(0xc693408)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCH
>Mature Secondary Structure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HHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1435726