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The map label for this gene is hisK [H]

Identifier: 52143930

GI number: 52143930

Start: 1389676

End: 1390692

Strand: Direct

Name: hisK [H]

Synonym: BCZK1298

Alternate gene names: 52143930

Gene position: 1389676-1390692 (Clockwise)

Preceding gene: 52143933

Following gene: 52143931

Centisome position: 26.22

GC content: 35.2

Gene sequence:

>1017_bases
ATGAAAGTGGATTATCACATTCATTTAGAAGAAGGACCATATTCAATAGGGTGGCTAGCTAAAATAAATGAAGCACTGCA
ACACTATGAACCGCTAAAAGAAGAAAAACATTCTATGGAATGGCTTGTGAAAACACAAGAACGCCTGCAAAGACGTGTGA
AAGAAGGGCCATTTACAACGAAATGGATTGATTTATATTTAGAAGAAGCTTTGCGAAAAGGGATAAAAGAAGTTGGTATT
GTCGATCATTTATACCGTTTTTATGAAGCGAAAGAATACTATGAAAAATATGTTGATATTAGTGATTCAGGGCTTGGATG
TTTACAAAAGGAATGGTTAGACCAAGTGAGGGTAGCTTCACTACATGATTTTACAAAGGCAATTGAAGAGGCGAAAGAAC
GGTGGAGTAAAAGAGGTGTTACGCTTAAACTTGGCATTGAAGCGGATTATTTTATTGGTGGTGAACAAGAATTACAACCT
TTACTCGCATTAGGAGATTTTGATTATGTAATTGGTTCTGTTCATTTTTTAAATGGCTGGGGATTTGATAATCCAGATAC
GAAAGAATATTTTAAGGAACATGACTTATACGCTTTATATGATACGTTTTTCAAAACGGTTGAGTGCGCAGTTCGTTCTG
AGTTATTTGATATTATTGCTCATCTTGACAACATAAAAGTATTTAATTATCGGTTAGATGGGAATGAACAACTTTCTTAT
TACAAGGAAATTGCACGTGCATTAGTAGAAACAAATACGGCAACGGAAATAAATGCGGGGTTGTATTATCGTTATCCTGT
GCGCGAAATGTGCCCGAGTCCGCTCTATTTACAAGTATTAGCTAAACACGAAGTTCCGATTACACTTTCTTCAGATGCTC
ATTATCCAAACGATTTAGGAAAATATGTGGAAGAGAATGTAAAAACGTTACGTAATCATAATATTTCTCACTTAGCTACA
TTTACGAAACGAGTCAGAACGATGAGATTACTAGAAGAAGCAACAATTTCAAAATGA

Upstream 100 bases:

>100_bases
TACCATTAAAAGATATTATGGAGGAAGTGACAGAAAGAAATGGGAAGCTTTCAAGAGTAGGGGACAGAAGAGAAATAGAT
ACATTATAGGGGGAATATGT

Downstream 100 bases:

>100_bases
TCACGATTTTTTGATGAAAACCGTTCTTTTTGTTCAAAATAAGAAAGAATAAAAAGGAGGGTAAGAAATGGCGAAACAAC
AAAATAAACAAAATGTACAA

Product: histidinol-phosphatase

Products: NA

Alternate protein names: HolPase [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKVDYHIHLEEGPYSIGWLAKINEALQHYEPLKEEKHSMEWLVKTQERLQRRVKEGPFTTKWIDLYLEEALRKGIKEVGI
VDHLYRFYEAKEYYEKYVDISDSGLGCLQKEWLDQVRVASLHDFTKAIEEAKERWSKRGVTLKLGIEADYFIGGEQELQP
LLALGDFDYVIGSVHFLNGWGFDNPDTKEYFKEHDLYALYDTFFKTVECAVRSELFDIIAHLDNIKVFNYRLDGNEQLSY
YKEIARALVETNTATEINAGLYYRYPVREMCPSPLYLQVLAKHEVPITLSSDAHYPNDLGKYVEENVKTLRNHNISHLAT
FTKRVRTMRLLEEATISK

Sequences:

>Translated_338_residues
MKVDYHIHLEEGPYSIGWLAKINEALQHYEPLKEEKHSMEWLVKTQERLQRRVKEGPFTTKWIDLYLEEALRKGIKEVGI
VDHLYRFYEAKEYYEKYVDISDSGLGCLQKEWLDQVRVASLHDFTKAIEEAKERWSKRGVTLKLGIEADYFIGGEQELQP
LLALGDFDYVIGSVHFLNGWGFDNPDTKEYFKEHDLYALYDTFFKTVECAVRSELFDIIAHLDNIKVFNYRLDGNEQLSY
YKEIARALVETNTATEINAGLYYRYPVREMCPSPLYLQVLAKHEVPITLSSDAHYPNDLGKYVEENVKTLRNHNISHLAT
FTKRVRTMRLLEEATISK
>Mature_338_residues
MKVDYHIHLEEGPYSIGWLAKINEALQHYEPLKEEKHSMEWLVKTQERLQRRVKEGPFTTKWIDLYLEEALRKGIKEVGI
VDHLYRFYEAKEYYEKYVDISDSGLGCLQKEWLDQVRVASLHDFTKAIEEAKERWSKRGVTLKLGIEADYFIGGEQELQP
LLALGDFDYVIGSVHFLNGWGFDNPDTKEYFKEHDLYALYDTFFKTVECAVRSELFDIIAHLDNIKVFNYRLDGNEQLSY
YKEIARALVETNTATEINAGLYYRYPVREMCPSPLYLQVLAKHEVPITLSSDAHYPNDLGKYVEENVKTLRNHNISHLAT
FTKRVRTMRLLEEATISK

Specific function: Unknown

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHP hydrolase family. HisK subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010140
- InterPro:   IPR004013
- InterPro:   IPR016195 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =3.1.3.15 [H]

Molecular weight: Translated: 39653; Mature: 39653

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVDYHIHLEEGPYSIGWLAKINEALQHYEPLKEEKHSMEWLVKTQERLQRRVKEGPFTT
CCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
KWIDLYLEEALRKGIKEVGIVDHLYRFYEAKEYYEKYVDISDSGLGCLQKEWLDQVRVAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
LHDFTKAIEEAKERWSKRGVTLKLGIEADYFIGGEQELQPLLALGDFDYVIGSVHFLNGW
HHHHHHHHHHHHHHHHHCCCEEEEECCCCEEECCHHHHHHHHHHCCHHHHHHHHHEECCC
GFDNPDTKEYFKEHDLYALYDTFFKTVECAVRSELFDIIAHLDNIKVFNYRLDGNEQLSY
CCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCHHHHH
YKEIARALVETNTATEINAGLYYRYPVREMCPSPLYLQVLAKHEVPITLSSDAHYPNDLG
HHHHHHHHHHCCCCCEECCCEEEECCHHHHCCCCHHHHHHHHCCCCEEECCCCCCCHHHH
KYVEENVKTLRNHNISHLATFTKRVRTMRLLEEATISK
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVDYHIHLEEGPYSIGWLAKINEALQHYEPLKEEKHSMEWLVKTQERLQRRVKEGPFTT
CCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
KWIDLYLEEALRKGIKEVGIVDHLYRFYEAKEYYEKYVDISDSGLGCLQKEWLDQVRVAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
LHDFTKAIEEAKERWSKRGVTLKLGIEADYFIGGEQELQPLLALGDFDYVIGSVHFLNGW
HHHHHHHHHHHHHHHHHCCCEEEEECCCCEEECCHHHHHHHHHHCCHHHHHHHHHEECCC
GFDNPDTKEYFKEHDLYALYDTFFKTVECAVRSELFDIIAHLDNIKVFNYRLDGNEQLSY
CCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCHHHHH
YKEIARALVETNTATEINAGLYYRYPVREMCPSPLYLQVLAKHEVPITLSSDAHYPNDLG
HHHHHHHHHHCCCCCEECCCEEEECCHHHHCCCCHHHHHHHHCCCCEEECCCCCCCHHHH
KYVEENVKTLRNHNISHLATFTKRVRTMRLLEEATISK
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]