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The map label for this gene is atoS [H]

Identifier: 52143890

GI number: 52143890

Start: 1431826

End: 1433088

Strand: Reverse

Name: atoS [H]

Synonym: BCZK1339

Alternate gene names: 52143890

Gene position: 1433088-1431826 (Counterclockwise)

Preceding gene: 52143889

Following gene: 52143891

Centisome position: 27.03

GC content: 30.09

Gene sequence:

>1263_bases
ATGCTTCCAAACGATGATATTATATCTCATGAAAAACGAATAGAAGAACTAGAGAATAAAGTGCGTTTTTATGAAGAACT
TGTAAATCAATTACCACATCATTTCACATATAAAAATCCACATATTGGTTTACAAATAAAGAAAACGAGATCAACTCATT
CCATTCAAAACATACAAAAAGAGAATAAAGAGGCTGACTTTCAACTTACTTGCGATTCATTATTTTTATTTAAACAACTT
GAAACATACTTTATTCATATTTTTGATGCTTTTTCACATCATGTAACCTTTGTTGATAATAATGGAAATATAACTTTATG
TAATCAGGCTGCAGCAGATGATTTTGGTGTAGTACGAAATGATATAATTGGAAAACCAATTCAACAATTACTAAAATTGC
CTGAAGAAAAAATTAAAGCTCTAGAAACATTAAGAACAGGCACAGAAATATATAATGAAGAAGTTTTAGACAAAAACTAT
GGCATTTTAAATAACCGAATTATTCGTGATTATAACGGAGAGATTTTTAGGGTTATTAGTGTCTTTCATTATTTAAACAC
AGAACGTGATGCAGAAAAATTTTCGTTAGCAGGGCGAATCGCAGCTGGTATTGCACATGAAGTACGTAACCCTCTTACAA
CCGTACGAGGATATTTACAATTTTTACAAGAAAATGTTTCTCCATCTAATAAAGAACTATTTAAAAACTTACTTATTCCT
GAATTAGATCGCGCAAATAGTATCATTACAAAATTTTTATCTATTTCAAAAACACGCGAATTTACAAGAGAACCCTTTCC
CATTAATACATTTTTACGTGAGTATATTCAACAGTTACTAGCTAGCGAAGTCTTTTTACATAACATTTCAATTGATTATA
ATTTTTCTACCGAATTAGATGATATTTTAGTTCATATTGATCGTCATGAACTTGTGCAAGTTTTTTTAAACTTATTCCAG
AACGCTGTCGATGCTCAAGGAGAAAAAAAACTTTCTATACAAATCACTAGTTACCGCCTTGATAATTTTGTTCGTATTAC
TTTCACTGATAATGGGACTGGTATTCCACCAGCGATTCAAGAATATATCTTTGATCCATTCTTCTCAACAAAAGATTCCG
GCACAGGTTTGGGCTTGTCAGTAACGAAAAAAATTATTCAAAATCATAATGGTACATTAAAAATGACTAGTAATGAAGAT
GGTACTACTTTTACTATTTCAATTCCAATCTTACCTAAAACAGCCCTTGAAAGATTAAATTAA

Upstream 100 bases:

>100_bases
GACCAATCAATTTCATTAAGTAGTCCCATCTTTAAGAGTATTCATATAAAAATATGATATACTAGATGGAAGAATTTTTA
AATTGAGGGGTTATTTATTT

Downstream 100 bases:

>100_bases
TACACATAAAATCCACTCCACTCCACGAACTGCATGTCAATTGTTAATCCTTCAACAATTGACATGCAGTTTTTTATGTT
GAACTTCTCTTCTTTACATT

Product: sensor histidine kinase, C-terminal region; sporulation kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MLPNDDIISHEKRIEELENKVRFYEELVNQLPHHFTYKNPHIGLQIKKTRSTHSIQNIQKENKEADFQLTCDSLFLFKQL
ETYFIHIFDAFSHHVTFVDNNGNITLCNQAAADDFGVVRNDIIGKPIQQLLKLPEEKIKALETLRTGTEIYNEEVLDKNY
GILNNRIIRDYNGEIFRVISVFHYLNTERDAEKFSLAGRIAAGIAHEVRNPLTTVRGYLQFLQENVSPSNKELFKNLLIP
ELDRANSIITKFLSISKTREFTREPFPINTFLREYIQQLLASEVFLHNISIDYNFSTELDDILVHIDRHELVQVFLNLFQ
NAVDAQGEKKLSIQITSYRLDNFVRITFTDNGTGIPPAIQEYIFDPFFSTKDSGTGLGLSVTKKIIQNHNGTLKMTSNED
GTTFTISIPILPKTALERLN

Sequences:

>Translated_420_residues
MLPNDDIISHEKRIEELENKVRFYEELVNQLPHHFTYKNPHIGLQIKKTRSTHSIQNIQKENKEADFQLTCDSLFLFKQL
ETYFIHIFDAFSHHVTFVDNNGNITLCNQAAADDFGVVRNDIIGKPIQQLLKLPEEKIKALETLRTGTEIYNEEVLDKNY
GILNNRIIRDYNGEIFRVISVFHYLNTERDAEKFSLAGRIAAGIAHEVRNPLTTVRGYLQFLQENVSPSNKELFKNLLIP
ELDRANSIITKFLSISKTREFTREPFPINTFLREYIQQLLASEVFLHNISIDYNFSTELDDILVHIDRHELVQVFLNLFQ
NAVDAQGEKKLSIQITSYRLDNFVRITFTDNGTGIPPAIQEYIFDPFFSTKDSGTGLGLSVTKKIIQNHNGTLKMTSNED
GTTFTISIPILPKTALERLN
>Mature_420_residues
MLPNDDIISHEKRIEELENKVRFYEELVNQLPHHFTYKNPHIGLQIKKTRSTHSIQNIQKENKEADFQLTCDSLFLFKQL
ETYFIHIFDAFSHHVTFVDNNGNITLCNQAAADDFGVVRNDIIGKPIQQLLKLPEEKIKALETLRTGTEIYNEEVLDKNY
GILNNRIIRDYNGEIFRVISVFHYLNTERDAEKFSLAGRIAAGIAHEVRNPLTTVRGYLQFLQENVSPSNKELFKNLLIP
ELDRANSIITKFLSISKTREFTREPFPINTFLREYIQQLLASEVFLHNISIDYNFSTELDDILVHIDRHELVQVFLNLFQ
NAVDAQGEKKLSIQITSYRLDNFVRITFTDNGTGIPPAIQEYIFDPFFSTKDSGTGLGLSVTKKIIQNHNGTLKMTSNED
GTTFTISIPILPKTALERLN

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=344, Percent_Identity=32.2674418604651, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI1790436, Length=222, Percent_Identity=33.7837837837838, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1790300, Length=353, Percent_Identity=27.1954674220963, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1788393, Length=222, Percent_Identity=27.4774774774775, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87081816, Length=249, Percent_Identity=28.9156626506024, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788713, Length=220, Percent_Identity=26.3636363636364, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789808, Length=252, Percent_Identity=24.6031746031746, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1786912, Length=224, Percent_Identity=25, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786783, Length=251, Percent_Identity=27.8884462151394, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI145693157, Length=273, Percent_Identity=26.3736263736264, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1789149, Length=239, Percent_Identity=25.9414225941423, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1786600, Length=336, Percent_Identity=23.8095238095238, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI48994928, Length=441, Percent_Identity=22.4489795918367, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48411; Mature: 48411

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPNDDIISHEKRIEELENKVRFYEELVNQLPHHFTYKNPHIGLQIKKTRSTHSIQNIQK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHH
ENKEADFQLTCDSLFLFKQLETYFIHIFDAFSHHVTFVDNNGNITLCNQAAADDFGVVRN
HCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEECCCCCCHHHHHHH
DIIGKPIQQLLKLPEEKIKALETLRTGTEIYNEEVLDKNYGILNNRIIRDYNGEIFRVIS
HHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCEEECCCCHHHHHHH
VFHYLNTERDAEKFSLAGRIAAGIAHEVRNPLTTVRGYLQFLQENVSPSNKELFKNLLIP
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
ELDRANSIITKFLSISKTREFTREPFPINTFLREYIQQLLASEVFLHNISIDYNFSTELD
CCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHH
DILVHIDRHELVQVFLNLFQNAVDAQGEKKLSIQITSYRLDNFVRITFTDNGTGIPPAIQ
HHHEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCEEEEEEECCCCCCCHHHH
EYIFDPFFSTKDSGTGLGLSVTKKIIQNHNGTLKMTSNEDGTTFTISIPILPKTALERLN
HHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCHHHHHHCC
>Mature Secondary Structure
MLPNDDIISHEKRIEELENKVRFYEELVNQLPHHFTYKNPHIGLQIKKTRSTHSIQNIQK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHH
ENKEADFQLTCDSLFLFKQLETYFIHIFDAFSHHVTFVDNNGNITLCNQAAADDFGVVRN
HCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEECCCCCCHHHHHHH
DIIGKPIQQLLKLPEEKIKALETLRTGTEIYNEEVLDKNYGILNNRIIRDYNGEIFRVIS
HHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCEEECCCCHHHHHHH
VFHYLNTERDAEKFSLAGRIAAGIAHEVRNPLTTVRGYLQFLQENVSPSNKELFKNLLIP
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
ELDRANSIITKFLSISKTREFTREPFPINTFLREYIQQLLASEVFLHNISIDYNFSTELD
CCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHH
DILVHIDRHELVQVFLNLFQNAVDAQGEKKLSIQITSYRLDNFVRITFTDNGTGIPPAIQ
HHHEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCEEEEEEECCCCCCCHHHH
EYIFDPFFSTKDSGTGLGLSVTKKIIQNHNGTLKMTSNEDGTTFTISIPILPKTALERLN
HHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]