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The map label for this gene is xpt [H]

Identifier: 52143783

GI number: 52143783

Start: 1532691

End: 1533284

Strand: Direct

Name: xpt [H]

Synonym: BCZK1448

Alternate gene names: 52143783

Gene position: 1532691-1533284 (Clockwise)

Preceding gene: 52143784

Following gene: 52143782

Centisome position: 28.91

GC content: 34.51

Gene sequence:

>594_bases
ATGAAAGTATTACAAGAAAAGATTTTGAACGAAGGAAAGGTTTTATCTGGTGACGTATTAAAGGTAGATGCTTTTTTAAA
TCATCAAATTGATCCAGTACTTATGCAAGAAATCGGAAAAGAATTTGCTAAACGTTTTAAAGAAGAGAACATTACAAAAA
TCGTGACGATTGAATCTTCAGGCATTGCACCAGCAGTTATGGCTGCACTAGAGCTTGGTGTAAAAGTAATTTTTGCAAGA
AAACGTAAATCGTTAACGTTACAAGATAATATGTATGTTGCAAGCGTATATTCATTTACAAAACAAGAAACGAATGAAAT
TTCATTATCTCGAAATCATATTGATGAAAGTGATCGCGTTTTAATCATCGATGACTTTTTAGCGAACGGTCAGGCTGCTT
TAGGTTTAATGAGTTTAGTTGAGCAAGCAGGAGCAAGTATTGCAGGAATTGGTATTGTTATTGAAAAAGCATTTCAAGAT
GGAGGAAAGAAGCTTCGTGAACAAGGAATTCGTGTTGAGTCACTAGCAGAAATTGCATCACTTGATAATAACGCAGTTAC
ATTTGTACAGCAAGAAACTGCGGAGGTGAAATAA

Upstream 100 bases:

>100_bases
TTAGCATTCTTTTTTGCGAAACTCCAAAAGCGCGTCTCTCACTTGTAACGAGTGGTGGCAGCTTTTGGAGTTTTTTTATT
GCATAAGAGGGGGAACAAAC

Downstream 100 bases:

>100_bases
ACGATGAAGCAACATCCATTTAAAATCGCATCGCTTGGTATGCAGCATATGCTTGCTATGTATGCTGGCGCAATTATCGT
TCCGCTTATTGTGGGCGGCG

Product: xanthine phosphoribosyltransferase

Products: NA

Alternate protein names: XPRTase [H]

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MKVLQEKILNEGKVLSGDVLKVDAFLNHQIDPVLMQEIGKEFAKRFKEENITKIVTIESSGIAPAVMAALELGVKVIFAR
KRKSLTLQDNMYVASVYSFTKQETNEISLSRNHIDESDRVLIIDDFLANGQAALGLMSLVEQAGASIAGIGIVIEKAFQD
GGKKLREQGIRVESLAEIASLDNNAVTFVQQETAEVK

Sequences:

>Translated_197_residues
MKVLQEKILNEGKVLSGDVLKVDAFLNHQIDPVLMQEIGKEFAKRFKEENITKIVTIESSGIAPAVMAALELGVKVIFAR
KRKSLTLQDNMYVASVYSFTKQETNEISLSRNHIDESDRVLIIDDFLANGQAALGLMSLVEQAGASIAGIGIVIEKAFQD
GGKKLREQGIRVESLAEIASLDNNAVTFVQQETAEVK
>Mature_197_residues
MKVLQEKILNEGKVLSGDVLKVDAFLNHQIDPVLMQEIGKEFAKRFKEENITKIVTIESSGIAPAVMAALELGVKVIFAR
KRKSLTLQDNMYVASVYSFTKQETNEISLSRNHIDESDRVLIIDDFLANGQAALGLMSLVEQAGASIAGIGIVIEKAFQD
GGKKLREQGIRVESLAEIASLDNNAVTFVQQETAEVK

Specific function: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR010079 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 21605; Mature: 21605

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLQEKILNEGKVLSGDVLKVDAFLNHQIDPVLMQEIGKEFAKRFKEENITKIVTIESS
CCHHHHHHHCCCCEECCCEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GIAPAVMAALELGVKVIFARKRKSLTLQDNMYVASVYSFTKQETNEISLSRNHIDESDRV
CCHHHHHHHHHHHHHHEEECCCCCEEEECCEEHHHHHHHHHHCCHHEEHHHCCCCCCCCE
LIIDDFLANGQAALGLMSLVEQAGASIAGIGIVIEKAFQDGGKKLREQGIRVESLAEIAS
EEEECCCCCCHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LDNNAVTFVQQETAEVK
CCCCEEEEEECCCCCCC
>Mature Secondary Structure
MKVLQEKILNEGKVLSGDVLKVDAFLNHQIDPVLMQEIGKEFAKRFKEENITKIVTIESS
CCHHHHHHHCCCCEECCCEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GIAPAVMAALELGVKVIFARKRKSLTLQDNMYVASVYSFTKQETNEISLSRNHIDESDRV
CCHHHHHHHHHHHHHHEEECCCCCEEEECCEEHHHHHHHHHHCCHHEEHHHCCCCCCCCE
LIIDDFLANGQAALGLMSLVEQAGASIAGIGIVIEKAFQDGGKKLREQGIRVESLAEIAS
EEEECCCCCCHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LDNNAVTFVQQETAEVK
CCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA