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The map label for this gene is lacC [H]

Identifier: 52143592

GI number: 52143592

Start: 1730051

End: 1730974

Strand: Direct

Name: lacC [H]

Synonym: BCZK1642

Alternate gene names: 52143592

Gene position: 1730051-1730974 (Clockwise)

Preceding gene: 52143593

Following gene: 52143591

Centisome position: 32.64

GC content: 36.47

Gene sequence:

>924_bases
ATGATTGCGACAATTACATTGAATCCATCTGTTGATATGCGATATGAATTAGGAGAATTAAAACTAAACAAAATACATCG
CACGAAAGACTATGAAAAAACTGCGGGTGGAAAAGGCATTAATGTATCGAGAGTACTTCGTTTGCTTGGAGAAGAAGTAA
CAGGAGCTGGGTTACTTGGTGGTAGTAATGGTGAGTTCATAAGAAAAAGATTGAGAGATTTATCAATTATTGATGAGTTT
GTTTCCGTTAAAGAAGAAACTCGCAATTGTATAGCGTTAATCACAAAAAAATCTGCGTCAGCTACTGAAGTATTAGAAGC
AGGACCAGCTATTTCAGAGGATGAAATAGCTCTTTTTATAAAAAAATATGAAAGGATAGTAAAAGATTTTGAGTTTATTG
TTGCATCGGGAAGTTTACCTAAGGGTATTCCAAATTCATTTTATCAACAGTTGGCACAAAAGGCGGCTGAAAACGGTAAA
AAATTCATATTAGATACAAGTGGAGAACCATTATTGCATGGCATACAAGGAAAACCATTTTTAATTAAACCAAACAGGCA
AGAAATTTGTCAGTTGCTTCAAAAAAAACGTGTGTCACAGGAAGAAATGATTGCGGAAGCAACTAAAATCTGCGAGGGGG
GCGTGCAGTATGTTTTGTTATCACTTGGAAGAGAAGGAGCGATACTTATTACGAAAGATGAAAGCATAAGGGCAATTATT
TCAGAAATAAAAACTATCAATGCCGTTGGCTCAGGTGACGCAATGGTTGCAGGAATAACGTTAGCACTCGCAAAGGGGTA
TGGGATAAAGGATGCACTTCGTTTTTCGGTGGCGTGTGGAATGGCTAACGCAGCTGAGGAAATAACAGGTTACATACAGC
TTAAAAATGTAGAGAATTTCTATAATGAAATTACAATTGTCTAA

Upstream 100 bases:

>100_bases
GCGTAAATATTTTTCAGATGCAATTATGGCGATGAAACGGGTTGTTGCAGATAAAATAAAGATGTGCAAAAGTTTAAATC
GTGTGTAAGGAGATATTCTT

Downstream 100 bases:

>100_bases
AAGTAGGAAGGGGAGAAATATGGGGAAGTACGTTGCTTGTTTTGATATTGGAGGAACTTTTATAAAATATGCAATGATTG
ATGAACAAGGAATGGTACAT

Product: tagatose-6-phosphate kinase, phosphofructokinase I

Products: NA

Alternate protein names: Phosphotagatokinase [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MIATITLNPSVDMRYELGELKLNKIHRTKDYEKTAGGKGINVSRVLRLLGEEVTGAGLLGGSNGEFIRKRLRDLSIIDEF
VSVKEETRNCIALITKKSASATEVLEAGPAISEDEIALFIKKYERIVKDFEFIVASGSLPKGIPNSFYQQLAQKAAENGK
KFILDTSGEPLLHGIQGKPFLIKPNRQEICQLLQKKRVSQEEMIAEATKICEGGVQYVLLSLGREGAILITKDESIRAII
SEIKTINAVGSGDAMVAGITLALAKGYGIKDALRFSVACGMANAAEEITGYIQLKNVENFYNEITIV

Sequences:

>Translated_307_residues
MIATITLNPSVDMRYELGELKLNKIHRTKDYEKTAGGKGINVSRVLRLLGEEVTGAGLLGGSNGEFIRKRLRDLSIIDEF
VSVKEETRNCIALITKKSASATEVLEAGPAISEDEIALFIKKYERIVKDFEFIVASGSLPKGIPNSFYQQLAQKAAENGK
KFILDTSGEPLLHGIQGKPFLIKPNRQEICQLLQKKRVSQEEMIAEATKICEGGVQYVLLSLGREGAILITKDESIRAII
SEIKTINAVGSGDAMVAGITLALAKGYGIKDALRFSVACGMANAAEEITGYIQLKNVENFYNEITIV
>Mature_307_residues
MIATITLNPSVDMRYELGELKLNKIHRTKDYEKTAGGKGINVSRVLRLLGEEVTGAGLLGGSNGEFIRKRLRDLSIIDEF
VSVKEETRNCIALITKKSASATEVLEAGPAISEDEIALFIKKYERIVKDFEFIVASGSLPKGIPNSFYQQLAQKAAENGK
KFILDTSGEPLLHGIQGKPFLIKPNRQEICQLLQKKRVSQEEMIAEATKICEGGVQYVLLSLGREGAILITKDESIRAII
SEIKTINAVGSGDAMVAGITLALAKGYGIKDALRFSVACGMANAAEEITGYIQLKNVENFYNEITIV

Specific function: Unknown

COG id: COG1105

COG function: function code G; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family. LacC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788493, Length=262, Percent_Identity=30.5343511450382, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1788017, Length=311, Percent_Identity=29.903536977492, Blast_Score=119, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR005926
- InterPro:   IPR017583 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.144 [H]

Molecular weight: Translated: 33525; Mature: 33525

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: PS00583 PFKB_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIATITLNPSVDMRYELGELKLNKIHRTKDYEKTAGGKGINVSRVLRLLGEEVTGAGLLG
CEEEEEECCCCCEEEECCCHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHCCCCEEEC
GSNGEFIRKRLRDLSIIDEFVSVKEETRNCIALITKKSASATEVLEAGPAISEDEIALFI
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHCCCCCCCHHHHHHH
KKYERIVKDFEFIVASGSLPKGIPNSFYQQLAQKAAENGKKFILDTSGEPLLHGIQGKPF
HHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEECCCCCEE
LIKPNRQEICQLLQKKRVSQEEMIAEATKICEGGVQYVLLSLGREGAILITKDESIRAII
EECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEECCHHHHHHH
SEIKTINAVGSGDAMVAGITLALAKGYGIKDALRFSVACGMANAAEEITGYIQLKNVENF
HHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHEEHEEECCHHHH
YNEITIV
HHCEECC
>Mature Secondary Structure
MIATITLNPSVDMRYELGELKLNKIHRTKDYEKTAGGKGINVSRVLRLLGEEVTGAGLLG
CEEEEEECCCCCEEEECCCHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHCCCCEEEC
GSNGEFIRKRLRDLSIIDEFVSVKEETRNCIALITKKSASATEVLEAGPAISEDEIALFI
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHCCCCCCCHHHHHHH
KKYERIVKDFEFIVASGSLPKGIPNSFYQQLAQKAAENGKKFILDTSGEPLLHGIQGKPF
HHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEECCCCCEE
LIKPNRQEICQLLQKKRVSQEEMIAEATKICEGGVQYVLLSLGREGAILITKDESIRAII
EECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEECCHHHHHHH
SEIKTINAVGSGDAMVAGITLALAKGYGIKDALRFSVACGMANAAEEITGYIQLKNVENF
HHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHEEHEEECCHHHH
YNEITIV
HHCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12663927 [H]