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The map label for this gene is glcK [H]

Identifier: 52143591

GI number: 52143591

Start: 1730994

End: 1731935

Strand: Direct

Name: glcK [H]

Synonym: BCZK1643

Alternate gene names: 52143591

Gene position: 1730994-1731935 (Clockwise)

Preceding gene: 52143592

Following gene: 52143590

Centisome position: 32.65

GC content: 35.24

Gene sequence:

>942_bases
ATGGGGAAGTACGTTGCTTGTTTTGATATTGGAGGAACTTTTATAAAATATGCAATGATTGATGAACAAGGAATGGTACA
TGAACAAGGGAAAATAACAACACCAGTACAAAATCAAAAGAAAGAAATTTTGTATCGCATTTGTGAAGTAATATATGAGT
TTGAAAAGAGCTATAAAATTCATTCTGTAGGTGTATCATCGTGTGGGATTATTGATAATATCAAGGGGGAAGTTCTGTAT
TCTGCCAATATTTTGGGATATAGCGGTACAAAAATAGCAGATTACATTTATAGTGAGACAGGGTATGTGGCGAGTATTGA
AAATGATGTTCGTTCAGCTTGTCTCGGTGAAATGTGGAAAGGAGTAGGGCAGGGGAAAGAACATATTGTTTTAATCACAC
TTGGAACCGGAATTGGTAGTGGAATCATTATAAATGGCAAAATGCTTCAGGGAGTGAAAGGATTAGCAGGAGAGCTTGGT
CATATGATAATTGTTCATAATGGAGAAAAATGTAGTTGTGGCGGAGAGGGATGTTATGAGAGATATGCATCGACTTCGGC
ATTGATTCGTCAGTATAAAGAAGCATCAAAAATTCAAGGGCTAGAGATAGGTACAATCACAGGTGAAGAAATTATAGAAC
GTATGTACAGAGGAGAACGATTGGCAAAGGATGTATATGAACAGTTTCTACAGTATGTTGTTGCTGGTTTAGTAAATATT
ACTTATATATTTAACCCCGAATTAATTATTATTGGGGGAGGTATTACAGAGCAAGGTGAACCATTTTTGAAACAAATTCA
AGAAAGGTTCCATGACAAAATAATGGATATCTATCAAAATAAGGTGGAAATCGCTTTAGCATCATTACATAATGATGCTG
GTGTATATGGAGCTTGTTATGTAGCGTTGAATCAATGTGAGGAAAAGTCAATGAATATATAA

Upstream 100 bases:

>100_bases
GCTAACGCAGCTGAGGAAATAACAGGTTACATACAGCTTAAAAATGTAGAGAATTTCTATAATGAAATTACAATTGTCTA
AAAGTAGGAAGGGGAGAAAT

Downstream 100 bases:

>100_bases
TTTTAGAAGATATTTATCGAGAATAGTTAACACGTAGAGCTTTTTATTTTCAAACAACCATTATCTTGTTTATATATCAG
CTGATGGTTGTTTTTGTTTG

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MGKYVACFDIGGTFIKYAMIDEQGMVHEQGKITTPVQNQKKEILYRICEVIYEFEKSYKIHSVGVSSCGIIDNIKGEVLY
SANILGYSGTKIADYIYSETGYVASIENDVRSACLGEMWKGVGQGKEHIVLITLGTGIGSGIIINGKMLQGVKGLAGELG
HMIIVHNGEKCSCGGEGCYERYASTSALIRQYKEASKIQGLEIGTITGEEIIERMYRGERLAKDVYEQFLQYVVAGLVNI
TYIFNPELIIIGGGITEQGEPFLKQIQERFHDKIMDIYQNKVEIALASLHNDAGVYGACYVALNQCEEKSMNI

Sequences:

>Translated_313_residues
MGKYVACFDIGGTFIKYAMIDEQGMVHEQGKITTPVQNQKKEILYRICEVIYEFEKSYKIHSVGVSSCGIIDNIKGEVLY
SANILGYSGTKIADYIYSETGYVASIENDVRSACLGEMWKGVGQGKEHIVLITLGTGIGSGIIINGKMLQGVKGLAGELG
HMIIVHNGEKCSCGGEGCYERYASTSALIRQYKEASKIQGLEIGTITGEEIIERMYRGERLAKDVYEQFLQYVVAGLVNI
TYIFNPELIIIGGGITEQGEPFLKQIQERFHDKIMDIYQNKVEIALASLHNDAGVYGACYVALNQCEEKSMNI
>Mature_312_residues
GKYVACFDIGGTFIKYAMIDEQGMVHEQGKITTPVQNQKKEILYRICEVIYEFEKSYKIHSVGVSSCGIIDNIKGEVLYS
ANILGYSGTKIADYIYSETGYVASIENDVRSACLGEMWKGVGQGKEHIVLITLGTGIGSGIIINGKMLQGVKGLAGELGH
MIIVHNGEKCSCGGEGCYERYASTSALIRQYKEASKIQGLEIGTITGEEIIERMYRGERLAKDVYEQFLQYVVAGLVNIT
YIFNPELIIIGGGITEQGEPFLKQIQERFHDKIMDIYQNKVEIALASLHNDAGVYGACYVALNQCEEKSMNI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=257, Percent_Identity=28.7937743190661, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI298566325, Length=257, Percent_Identity=28.7937743190661, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI4885285, Length=257, Percent_Identity=28.7937743190661, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI190014632, Length=257, Percent_Identity=28.7937743190661, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI1787363, Length=311, Percent_Identity=27.3311897106109, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1786891, Length=273, Percent_Identity=24.9084249084249, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787878, Length=268, Percent_Identity=22.3880597014925, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI87081733, Length=257, Percent_Identity=22.9571984435798, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI87082127, Length=275, Percent_Identity=24, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790522, Length=260, Percent_Identity=23.8461538461538, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87082230, Length=274, Percent_Identity=23.7226277372263, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 34570; Mature: 34439

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKYVACFDIGGTFIKYAMIDEQGMVHEQGKITTPVQNQKKEILYRICEVIYEFEKSYKI
CCCEEEEEECCCHHEEEEEECCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEE
HSVGVSSCGIIDNIKGEVLYSANILGYSGTKIADYIYSETGYVASIENDVRSACLGEMWK
EECCCCCCCCEECCCCCEEEEEEEECCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHH
GVGQGKEHIVLITLGTGIGSGIIINGKMLQGVKGLAGELGHMIIVHNGEKCSCGGEGCYE
HCCCCCCEEEEEEECCCCCCCEEEECHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHH
RYASTSALIRQYKEASKIQGLEIGTITGEEIIERMYRGERLAKDVYEQFLQYVVAGLVNI
HHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHE
TYIFNPELIIIGGGITEQGEPFLKQIQERFHDKIMDIYQNKVEIALASLHNDAGVYGACY
EEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
VALNQCEEKSMNI
HHHHHHHHHCCCC
>Mature Secondary Structure 
GKYVACFDIGGTFIKYAMIDEQGMVHEQGKITTPVQNQKKEILYRICEVIYEFEKSYKI
CCEEEEEECCCHHEEEEEECCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEE
HSVGVSSCGIIDNIKGEVLYSANILGYSGTKIADYIYSETGYVASIENDVRSACLGEMWK
EECCCCCCCCEECCCCCEEEEEEEECCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHH
GVGQGKEHIVLITLGTGIGSGIIINGKMLQGVKGLAGELGHMIIVHNGEKCSCGGEGCYE
HCCCCCCEEEEEEECCCCCCCEEEECHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHH
RYASTSALIRQYKEASKIQGLEIGTITGEEIIERMYRGERLAKDVYEQFLQYVVAGLVNI
HHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHE
TYIFNPELIIIGGGITEQGEPFLKQIQERFHDKIMDIYQNKVEIALASLHNDAGVYGACY
EEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
VALNQCEEKSMNI
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]