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The map label for this gene is asbF [H]

Identifier: 52143434

GI number: 52143434

Start: 1927449

End: 1928291

Strand: Direct

Name: asbF [H]

Synonym: BCZK1800

Alternate gene names: 52143434

Gene position: 1927449-1928291 (Clockwise)

Preceding gene: 52143433

Following gene: 52143435

Centisome position: 36.36

GC content: 33.57

Gene sequence:

>843_bases
ATGAAATATTCACTATGTACCATTTCATTTCGCCATCAATTAATTTCATTTACTGATATTGTTCAATTTGCATATGAAAA
CGGTTTTGAAGGCATTGAATTGTGGGGGACTCATGCACAAAATTTGTATATGCAGGAGTATGAAACGACAGAACGAGAAT
TGAATTGTTTAAAGGATAAAACCTTGGAAATTACGATGATAAGTGATTACTTAGACATATCATTATCAGCAGATTTTGAA
AAAACGATAGAGAAATGTGAACAACTTGCAATACTAGCTAATTGGTTTAAAACGAACAAAATTCGTACGTTTGCTGGACA
AAAAGGTAGTGCAGATTTTTCGCAACAAGAGAGACAAGAGTATGTGAATCGTATTCGCATGATTTGTGAATTATTTGCTC
AGCATAATATGTATGTACTTTTAGAAACACACCCAAATACGTTAACGGATACGTTGCCTTCTACTTTGGAATTATTAGGC
GAAGTAGATCATCCGAATTTGAAAATAAATCTTGATTTTCTTCATATATGGGAGTCTGGTGCAGATCCAGTTGATAGCTT
CCAGCGACTAAGACCGTGGATAGAACATTACCATTTTAAGAATATATCTTCAGCAGATTATTTACATGTGTTCGAACCGA
ATAATGTATATGCAGCAGCGGGAAATCGTACTGGTATGGTTCCATTATTTGAAGGTATTGTAAATTATGATGAGATTATT
CAGGAAGTGAGAGATACTGACCATTTCGCTTCACTCGAATGGTTTGGACATAATGCGAAAGATATATTAAAAGCAGAAAT
GAAAGTACTAACAAATAGAAAATTAGAAGTAGTAACTTCTTAA

Upstream 100 bases:

>100_bases
TTAGAGAGACAGTTTTTATCATGGAAAGAAATGAAATCAAATGAGTCTGTCTTAGTATTTTAAAAACTTTACTGAATTTA
AGATAAGGGAGTTCAAACCT

Downstream 100 bases:

>100_bases
TATAAAATGATGAAAGAGTCTCTCATTGTAGAGACTCTTTTTTAAAAATATTAATAACCAAAAATTACCATGTATTTAAA
TTGAAATTTAACACAATTTA

Product: hypothetical protein

Products: NA

Alternate protein names: 3-DHS dehydratase; DHSase; Petrobactin biosynthesis protein AsbF [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MKYSLCTISFRHQLISFTDIVQFAYENGFEGIELWGTHAQNLYMQEYETTERELNCLKDKTLEITMISDYLDISLSADFE
KTIEKCEQLAILANWFKTNKIRTFAGQKGSADFSQQERQEYVNRIRMICELFAQHNMYVLLETHPNTLTDTLPSTLELLG
EVDHPNLKINLDFLHIWESGADPVDSFQRLRPWIEHYHFKNISSADYLHVFEPNNVYAAAGNRTGMVPLFEGIVNYDEII
QEVRDTDHFASLEWFGHNAKDILKAEMKVLTNRKLEVVTS

Sequences:

>Translated_280_residues
MKYSLCTISFRHQLISFTDIVQFAYENGFEGIELWGTHAQNLYMQEYETTERELNCLKDKTLEITMISDYLDISLSADFE
KTIEKCEQLAILANWFKTNKIRTFAGQKGSADFSQQERQEYVNRIRMICELFAQHNMYVLLETHPNTLTDTLPSTLELLG
EVDHPNLKINLDFLHIWESGADPVDSFQRLRPWIEHYHFKNISSADYLHVFEPNNVYAAAGNRTGMVPLFEGIVNYDEII
QEVRDTDHFASLEWFGHNAKDILKAEMKVLTNRKLEVVTS
>Mature_280_residues
MKYSLCTISFRHQLISFTDIVQFAYENGFEGIELWGTHAQNLYMQEYETTERELNCLKDKTLEITMISDYLDISLSADFE
KTIEKCEQLAILANWFKTNKIRTFAGQKGSADFSQQERQEYVNRIRMICELFAQHNMYVLLETHPNTLTDTLPSTLELLG
EVDHPNLKINLDFLHIWESGADPVDSFQRLRPWIEHYHFKNISSADYLHVFEPNNVYAAAGNRTGMVPLFEGIVNYDEII
QEVRDTDHFASLEWFGHNAKDILKAEMKVLTNRKLEVVTS

Specific function: Converts 3-dehydroshikimate to protocatechuate (3,4- dihydroxybenzoate), a biosynthetic unit required for the biosynthesis of petrobactin which is a virulence-associated siderophore produced by B.anthracis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: =4.2.1.118 [H]

Molecular weight: Translated: 32632; Mature: 32632

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYSLCTISFRHQLISFTDIVQFAYENGFEGIELWGTHAQNLYMQEYETTERELNCLKDK
CCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCC
TLEITMISDYLDISLSADFEKTIEKCEQLAILANWFKTNKIRTFAGQKGSADFSQQERQE
CEEEEEEECEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHH
YVNRIRMICELFAQHNMYVLLETHPNTLTDTLPSTLELLGEVDHPNLKINLDFLHIWESG
HHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCC
ADPVDSFQRLRPWIEHYHFKNISSADYLHVFEPNNVYAAAGNRTGMVPLFEGIVNYDEII
CCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEECCCCCCCHHHHHHHCCHHHHH
QEVRDTDHFASLEWFGHNAKDILKAEMKVLTNRKLEVVTS
HHHHCCCHHEEHHHCCCCHHHHHHHHHHHHHCCCEEEEEC
>Mature Secondary Structure
MKYSLCTISFRHQLISFTDIVQFAYENGFEGIELWGTHAQNLYMQEYETTERELNCLKDK
CCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCC
TLEITMISDYLDISLSADFEKTIEKCEQLAILANWFKTNKIRTFAGQKGSADFSQQERQE
CEEEEEEECEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHH
YVNRIRMICELFAQHNMYVLLETHPNTLTDTLPSTLELLGEVDHPNLKINLDFLHIWESG
HHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCC
ADPVDSFQRLRPWIEHYHFKNISSADYLHVFEPNNVYAAAGNRTGMVPLFEGIVNYDEII
CCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEECCCCCCCHHHHHHHCCHHHHH
QEVRDTDHFASLEWFGHNAKDILKAEMKVLTNRKLEVVTS
HHHHCCCHHEEHHHCCCCHHHHHHHHHHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]