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The map label for this gene is yetH [H]

Identifier: 52143318

GI number: 52143318

Start: 2030327

End: 2030710

Strand: Direct

Name: yetH [H]

Synonym: BCZK1918

Alternate gene names: 52143318

Gene position: 2030327-2030710 (Clockwise)

Preceding gene: 52143320

Following gene: 52143316

Centisome position: 38.3

GC content: 33.59

Gene sequence:

>384_bases
ATGATCCATAAAGTAGGACAAATTATGTTATATGTAAATAATCAAGATGAGGCAGTCAATTTTTGGACGGAAAAGGTAGG
GTTTCATGTAGTAGCAGAGGAAGATAACAAGCAAGGAATGAGATGGATTGAAATCGCTCCGACTAACGGTGCTGAAACGA
GCATTATACTACATAATAAAGAAGTGATTTCTAAAATGAGCCCAGAATTGAATCTTGGTACACCATCTTTAATGTTCTTC
TCAGAAAATCTTGATCAATTATATACAGATTTAACAAATAAAAATGTTACTGTTGGAGAAATGGTAACTATGCCTTCTGG
TAAAGTGTTTAACTTTGCTGATAGTGAAGGGAATTATTTTGCGGTTATGGAAAAGAACCAATAA

Upstream 100 bases:

>100_bases
TCGATAAATTTTGCAAAGAAGTACATACCAACTCAAAAGGAATAACGATAGTACCTGTAGAAAGCTACATAGAATATAAA
AACCATTAGGGGGAAATGTA

Downstream 100 bases:

>100_bases
TAATATTGTTATGTGAAAATCCCCCCTCAAATATATTGAGGGGGATTACATGTTTGAAGTGGATTTTTCATTAGAGAGTT
GATTAATATAAAATACGCCT

Product: lactoylglutathione lyase

Products: glutathione; methylglyoxal

Alternate protein names: NA

Number of amino acids: Translated: 127; Mature: 127

Protein sequence:

>127_residues
MIHKVGQIMLYVNNQDEAVNFWTEKVGFHVVAEEDNKQGMRWIEIAPTNGAETSIILHNKEVISKMSPELNLGTPSLMFF
SENLDQLYTDLTNKNVTVGEMVTMPSGKVFNFADSEGNYFAVMEKNQ

Sequences:

>Translated_127_residues
MIHKVGQIMLYVNNQDEAVNFWTEKVGFHVVAEEDNKQGMRWIEIAPTNGAETSIILHNKEVISKMSPELNLGTPSLMFF
SENLDQLYTDLTNKNVTVGEMVTMPSGKVFNFADSEGNYFAVMEKNQ
>Mature_127_residues
MIHKVGQIMLYVNNQDEAVNFWTEKVGFHVVAEEDNKQGMRWIEIAPTNGAETSIILHNKEVISKMSPELNLGTPSLMFF
SENLDQLYTDLTNKNVTVGEMVTMPSGKVFNFADSEGNYFAVMEKNQ

Specific function: Unknown

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 4.4.1.5

Molecular weight: Translated: 14379; Mature: 14379

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.3 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.3 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHKVGQIMLYVNNQDEAVNFWTEKVGFHVVAEEDNKQGMRWIEIAPTNGAETSIILHNK
CCCCCCEEEEEECCCCCEEEEEECCCCEEEEEECCCCCCCEEEEEECCCCCCEEEEEECH
EVISKMSPELNLGTPSLMFFSENLDQLYTDLTNKNVTVGEMVTMPSGKVFNFADSEGNYF
HHHHHCCCCCCCCCCEEEEECCCHHHHHHHHCCCCEEEEEEEECCCCCEEEEECCCCCEE
AVMEKNQ
EEEECCC
>Mature Secondary Structure
MIHKVGQIMLYVNNQDEAVNFWTEKVGFHVVAEEDNKQGMRWIEIAPTNGAETSIILHNK
CCCCCCEEEEEECCCCCEEEEEECCCCEEEEEECCCCCCCEEEEEECCCCCCEEEEEECH
EVISKMSPELNLGTPSLMFFSENLDQLYTDLTNKNVTVGEMVTMPSGKVFNFADSEGNYF
HHHHHCCCCCCCCCCEEEEECCCHHHHHHHHCCCCEEEEEEEECCCCCEEEEECCCCCEE
AVMEKNQ
EEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]