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The map label for this gene is rpoE [H]

Identifier: 52143316

GI number: 52143316

Start: 2032616

End: 2033194

Strand: Direct

Name: rpoE [H]

Synonym: BCZK1921

Alternate gene names: 52143316

Gene position: 2032616-2033194 (Clockwise)

Preceding gene: 52143318

Following gene: 52143315

Centisome position: 38.34

GC content: 31.43

Gene sequence:

>579_bases
ATGAAGGGTGAAATAGATGACACACATTTAATCCAATTAACTTTATCGGGCAATAAAGAAGCGTATAGCGAATTGTATGA
TAAAACAATCCAAGAAGTATATAAAACAGCACATTTTTTAATAGATGATAAAGCAGATGTAGATGATGTCGTTCAAGAAA
TATACATACAGCTATATGAATCGCTTCGTAAGTATGATAGCGAGAAGCCATTTCGTCCTTGGCTAATTGGACTTGCAATT
AAACAAATTCATTCTTATAGAAGAAAGAGGTGGATGCGACTACGAATTATAAAAAAAGCACAAGAGCAAAGAAAACCGGT
ACAAATTGATTTTTCTAGCGATGTTGTAAGTAAAATATCAAACCAAAAATTAATCGAACTTATTCATAAATTACCGTATA
AATTGAAACAAGTTATTATCTTAAGATACTTACACGATTACTCTCAAGAAGAAGTAGCACAAATATTACATATTCCAATT
GGTACTGTGAAATCTAGAATTCACGCAGCATTAAAAAAACTACGTCAAAAAGAGCAAATAGAAGAAATCTTTTTGGGAGA
GGTAGGGAATGTGAAATGA

Upstream 100 bases:

>100_bases
ATTGAATCATTATATTAATTTATATAAAATTTTCTAGAAAAATCGAACGAAATATAAATTACTTGCCAATATATTGTGTA
AGACAAAGGAGGGCTGGAAT

Downstream 100 bases:

>100_bases
GTTTAGATTGTAGAGTTAGAGAATCTATACAAGAAGAAGCGAAGGGGATTGTTGCCCCGCCGGAGTTGAAAGAAAAAGTA
ATCGTTCAAATAAAAATGAA

Product: RNA polymerase sigma factor

Products: NA

Alternate protein names: Sigma-24 [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MKGEIDDTHLIQLTLSGNKEAYSELYDKTIQEVYKTAHFLIDDKADVDDVVQEIYIQLYESLRKYDSEKPFRPWLIGLAI
KQIHSYRRKRWMRLRIIKKAQEQRKPVQIDFSSDVVSKISNQKLIELIHKLPYKLKQVIILRYLHDYSQEEVAQILHIPI
GTVKSRIHAALKKLRQKEQIEEIFLGEVGNVK

Sequences:

>Translated_192_residues
MKGEIDDTHLIQLTLSGNKEAYSELYDKTIQEVYKTAHFLIDDKADVDDVVQEIYIQLYESLRKYDSEKPFRPWLIGLAI
KQIHSYRRKRWMRLRIIKKAQEQRKPVQIDFSSDVVSKISNQKLIELIHKLPYKLKQVIILRYLHDYSQEEVAQILHIPI
GTVKSRIHAALKKLRQKEQIEEIFLGEVGNVK
>Mature_192_residues
MKGEIDDTHLIQLTLSGNKEAYSELYDKTIQEVYKTAHFLIDDKADVDDVVQEIYIQLYESLRKYDSEKPFRPWLIGLAI
KQIHSYRRKRWMRLRIIKKAQEQRKPVQIDFSSDVVSKISNQKLIELIHKLPYKLKQVIILRYLHDYSQEEVAQILHIPI
GTVKSRIHAALKKLRQKEQIEEIFLGEVGNVK

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in heat shock and oxidative stress response; it is believed to control protein processing

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=198, Percent_Identity=27.7777777777778, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR014286
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 22741; Mature: 22741

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGEIDDTHLIQLTLSGNKEAYSELYDKTIQEVYKTAHFLIDDKADVDDVVQEIYIQLYE
CCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
SLRKYDSEKPFRPWLIGLAIKQIHSYRRKRWMRLRIIKKAQEQRKPVQIDFSSDVVSKIS
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHC
NQKLIELIHKLPYKLKQVIILRYLHDYSQEEVAQILHIPIGTVKSRIHAALKKLRQKEQI
CHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
EEIFLGEVGNVK
HHHHHCCCCCCC
>Mature Secondary Structure
MKGEIDDTHLIQLTLSGNKEAYSELYDKTIQEVYKTAHFLIDDKADVDDVVQEIYIQLYE
CCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
SLRKYDSEKPFRPWLIGLAIKQIHSYRRKRWMRLRIIKKAQEQRKPVQIDFSSDVVSKIS
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHC
NQKLIELIHKLPYKLKQVIILRYLHDYSQEEVAQILHIPIGTVKSRIHAALKKLRQKEQI
CHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
EEIFLGEVGNVK
HHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]