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The map label for this gene is gbsB [H]

Identifier: 52143232

GI number: 52143232

Start: 2128011

End: 2129213

Strand: Direct

Name: gbsB [H]

Synonym: BCZK2005

Alternate gene names: 52143232

Gene position: 2128011-2129213 (Clockwise)

Preceding gene: 52143234

Following gene: 52143230

Centisome position: 40.14

GC content: 36.33

Gene sequence:

>1203_bases
TTGCAAGAAGTTGCTGAGTTTCGTATGCCGAAGTCTGTATTATATGGAAGAAATTCTCTTGAAAAGCTGGGGGAACAATC
TAAGAAATTCGGGAAAAGAGCGTTTATAGTTACGGATACAATTATGGAGGATTTAGGATATGTTGAGAGGTGTATACAAC
AATTAAATACGAAAGGTATAACTGTTATTACATATAATAAAGTAAATGCTGAGCCTACAAATATACACGTGTTAGAGGCG
TTAACTATTTGTAAAGAAGGAAAGTGTGATTTTATAATCGGTCTTGGTGGTGGAAGTTGTATTGATGCAGCAAAAGCAGT
TACTGTGTTATATACAAATGGCGGAGAAGTGGAAGATTATGTCCAAAAGGATAGTGAAATAGACAATGATCCGCTACCAC
TTATTGCAATCCCAACAACTTCTGGAACTGGATCGGAAGTAACAAGTGTAGCAGTAATTACGAATAAACGAACAGATGTA
AAAATGATGATGAAGCATCCGAGTTTTACCCCGCAAGTAGCGATTATTGACCCGATTTTAACACGTTCGGTACCACCTCA
CATTACAGCAGCAACAGGGATCGATGCATTATGTCATGCAGTCGAAGCATATATTTCTAAAGTTTCACAATCACTTACAG
ATGTACTCGCTCTTTCAGCAATTGAAAGTATTATGAAATATTTACGTATTGCTTATGAAGATGGAGAGAATATGGAGGCA
AGAGAAGCGATGATGATTGCTTCCTTACAAGCTGGAATTGCATTTTCCAATGCATCTGTTACATTAGTTCATGGCATGTC
GAGACCAGTAGGAGCATTATTTCATGTACCACATGGTATATCGAATGCAATACTATTACCTACAGTTTTAGAATATACAA
AAGGTAGTGCGGTAAAAAGACTAGCGGAAATTGGCCGCTGTTTAAATAAAGATTTGTATTCCTATTGTGATGAAGAAGTA
GCCGACTACACGCTGGGGGAAATAAAAAAACTTTGTTTTGATCTTCGTATTCCAAATTTAAAAGAATACGGAATTGGTGA
AGTTGAGTTTGAAAAAGCTATTTCTAAAATGGCGTCAGATGCAATTGAAAGTGGAAGTCCAGCGAATAACCCACGTGTGC
CATCATATGATGAAATTAAACAGTTGTATCGAGAATGTTTTCATTATAAATATGAAGATTCAGTAAAAACATTAGGGGAT
TAA

Upstream 100 bases:

>100_bases
GCTGTGTTTTTAGTTATTGCATTCTATACAGTAACAGGAATTTATTAAGTCGATATTTTATGAACTAAAATATTAATTAG
GGTAAGAAGGGGTGGAGTAC

Downstream 100 bases:

>100_bases
TTTCAGAATATTCTTATAAAATTTCCTTGGAAATAGTTAAAACAAGACTTTATATTTCAAACGTAAAGCCTTGTTTTATT
ATGTATAATATACATAATAA

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: Alcohol dehydrogenase II; ADH II [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MQEVAEFRMPKSVLYGRNSLEKLGEQSKKFGKRAFIVTDTIMEDLGYVERCIQQLNTKGITVITYNKVNAEPTNIHVLEA
LTICKEGKCDFIIGLGGGSCIDAAKAVTVLYTNGGEVEDYVQKDSEIDNDPLPLIAIPTTSGTGSEVTSVAVITNKRTDV
KMMMKHPSFTPQVAIIDPILTRSVPPHITAATGIDALCHAVEAYISKVSQSLTDVLALSAIESIMKYLRIAYEDGENMEA
REAMMIASLQAGIAFSNASVTLVHGMSRPVGALFHVPHGISNAILLPTVLEYTKGSAVKRLAEIGRCLNKDLYSYCDEEV
ADYTLGEIKKLCFDLRIPNLKEYGIGEVEFEKAISKMASDAIESGSPANNPRVPSYDEIKQLYRECFHYKYEDSVKTLGD

Sequences:

>Translated_400_residues
MQEVAEFRMPKSVLYGRNSLEKLGEQSKKFGKRAFIVTDTIMEDLGYVERCIQQLNTKGITVITYNKVNAEPTNIHVLEA
LTICKEGKCDFIIGLGGGSCIDAAKAVTVLYTNGGEVEDYVQKDSEIDNDPLPLIAIPTTSGTGSEVTSVAVITNKRTDV
KMMMKHPSFTPQVAIIDPILTRSVPPHITAATGIDALCHAVEAYISKVSQSLTDVLALSAIESIMKYLRIAYEDGENMEA
REAMMIASLQAGIAFSNASVTLVHGMSRPVGALFHVPHGISNAILLPTVLEYTKGSAVKRLAEIGRCLNKDLYSYCDEEV
ADYTLGEIKKLCFDLRIPNLKEYGIGEVEFEKAISKMASDAIESGSPANNPRVPSYDEIKQLYRECFHYKYEDSVKTLGD
>Mature_400_residues
MQEVAEFRMPKSVLYGRNSLEKLGEQSKKFGKRAFIVTDTIMEDLGYVERCIQQLNTKGITVITYNKVNAEPTNIHVLEA
LTICKEGKCDFIIGLGGGSCIDAAKAVTVLYTNGGEVEDYVQKDSEIDNDPLPLIAIPTTSGTGSEVTSVAVITNKRTDV
KMMMKHPSFTPQVAIIDPILTRSVPPHITAATGIDALCHAVEAYISKVSQSLTDVLALSAIESIMKYLRIAYEDGENMEA
REAMMIASLQAGIAFSNASVTLVHGMSRPVGALFHVPHGISNAILLPTVLEYTKGSAVKRLAEIGRCLNKDLYSYCDEEV
ADYTLGEIKKLCFDLRIPNLKEYGIGEVEFEKAISKMASDAIESGSPANNPRVPSYDEIKQLYRECFHYKYEDSVKTLGD

Specific function: May Act On The Acetaldehyde Produced From The Degradation Of Ethanolamine. [C]

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=381, Percent_Identity=30.4461942257218, Blast_Score=151, Evalue=9e-37,
Organism=Escherichia coli, GI87082107, Length=390, Percent_Identity=37.4358974358974, Blast_Score=243, Evalue=1e-65,
Organism=Escherichia coli, GI48994951, Length=380, Percent_Identity=35, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI1789163, Length=381, Percent_Identity=32.8083989501312, Blast_Score=207, Evalue=9e-55,
Organism=Escherichia coli, GI1787493, Length=411, Percent_Identity=33.3333333333333, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI1789386, Length=347, Percent_Identity=23.9193083573487, Blast_Score=103, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17537053, Length=422, Percent_Identity=27.9620853080569, Blast_Score=140, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6321181, Length=393, Percent_Identity=35.6234096692112, Blast_Score=228, Evalue=2e-60,
Organism=Drosophila melanogaster, GI24657991, Length=345, Percent_Identity=31.0144927536232, Blast_Score=135, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 43870; Mature: 43870

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00913 ADH_IRON_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEVAEFRMPKSVLYGRNSLEKLGEQSKKFGKRAFIVTDTIMEDLGYVERCIQQLNTKGI
CCCHHHHCCCHHHHHCCHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHCCCCE
TVITYNKVNAEPTNIHVLEALTICKEGKCDFIIGLGGGSCIDAAKAVTVLYTNGGEVEDY
EEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCHHHHHHCEEEEEEECCCCHHHH
VQKDSEIDNDPLPLIAIPTTSGTGSEVTSVAVITNKRTDVKMMMKHPSFTPQVAIIDPIL
HHCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCCHHHHHHCCCCCCCEEEECHHH
TRSVPPHITAATGIDALCHAVEAYISKVSQSLTDVLALSAIESIMKYLRIAYEDGENMEA
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
REAMMIASLQAGIAFSNASVTLVHGMSRPVGALFHVPHGISNAILLPTVLEYTKGSAVKR
HHHHHHHHHHHCEEECCCCEEEEECCCCCHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHH
LAEIGRCLNKDLYSYCDEEVADYTLGEIKKLCFDLRIPNLKEYGIGEVEFEKAISKMASD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHH
AIESGSPANNPRVPSYDEIKQLYRECFHYKYEDSVKTLGD
HHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCC
>Mature Secondary Structure
MQEVAEFRMPKSVLYGRNSLEKLGEQSKKFGKRAFIVTDTIMEDLGYVERCIQQLNTKGI
CCCHHHHCCCHHHHHCCHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHCCCCE
TVITYNKVNAEPTNIHVLEALTICKEGKCDFIIGLGGGSCIDAAKAVTVLYTNGGEVEDY
EEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCHHHHHHCEEEEEEECCCCHHHH
VQKDSEIDNDPLPLIAIPTTSGTGSEVTSVAVITNKRTDVKMMMKHPSFTPQVAIIDPIL
HHCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCCHHHHHHCCCCCCCEEEECHHH
TRSVPPHITAATGIDALCHAVEAYISKVSQSLTDVLALSAIESIMKYLRIAYEDGENMEA
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
REAMMIASLQAGIAFSNASVTLVHGMSRPVGALFHVPHGISNAILLPTVLEYTKGSAVKR
HHHHHHHHHHHCEEECCCCEEEEECCCCCHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHH
LAEIGRCLNKDLYSYCDEEVADYTLGEIKKLCFDLRIPNLKEYGIGEVEFEKAISKMASD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHH
AIESGSPANNPRVPSYDEIKQLYRECFHYKYEDSVKTLGD
HHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3584063; 2308827; 2935393 [H]