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The map label for this gene is yfkC [H]

Identifier: 52143194

GI number: 52143194

Start: 2163560

End: 2164453

Strand: Direct

Name: yfkC [H]

Synonym: BCZK2044

Alternate gene names: 52143194

Gene position: 2163560-2164453 (Clockwise)

Preceding gene: 52143193

Following gene: 52143192

Centisome position: 40.81

GC content: 32.89

Gene sequence:

>894_bases
ATGAGTTTATTAACGTATACTGAAGAATTTTTTAATTATGTAAGGGAGTTTTTGCTTTTAAGATTTTTACTATTTGCTTT
AGTGCTGATTATTATTTCTTTTGTAATAAACCGCATTATTGATTGGTTTTTTAGGAAATCAAGCTTTTTTGATGAAGAGG
TAGAGCAAACGATTCAAAGTGTGATTCGATCTATTTTTAGATATATCATTATCATCAGTCTAATCATATATTTAATTAGC
CAATTTGTAGATATAAAAAGTATTATTGCAGGTGCAGGGATAGCAGGGGTTGTTATCGGTTTTGCTGCACAACAGATGCT
GAAAGATGTTATATTAGGCTTTGCGAGATTAGCGGACAAAGAGTTTCGTGTTGGCGATTTTGTTACGTTTAACGGAACAA
ACTCAGGAACGATTGAGGAAATTAGTATTCGTTTTATGCAAATTCGTGAATGGTCAGGAAAACTCCTTACCATACCACAT
GGAGAGATTAGAACGATACAAAATTTTAATAAAGGCTGGATGCGAGTAATTGAACGGATTACGGTAAGTTATCAGGAAGA
TCCTACAAGAGTTAAGGAATTGTTAGAGGAAGTTTGTGTTAATTGTAATGAAAAATTGGCCCCAAGTCTTTATAAAGTAG
AGGATGAAGCTGTTGAACCTTTTAAATATGTAGGTGTTACAGATTTAAACCCGAATCTGAAATACGTTGGATATGAATTT
TGTATTACAGGTTTAATAAAGCCAGAAGATTATTTTGAAACTTCTAGACAAGTAAGATTTGAATTAATGTCTATGTTCCA
TAAGAATCAAGTACAAATGCCAGCAGCAAATATGCTTGTTACTACTGAAAGTTTACAGCATACCCATGGTGGACAATCTT
TATCGGACAGCTAA

Upstream 100 bases:

>100_bases
ATACATAGTAAGGGTAGCGGCATTTTAGAGTAGGATAATAGATTTTTTTAGAACAAACTGAGACGATTATGAATTTTTTA
ATTAGTAAGGAAGTGATTAG

Downstream 100 bases:

>100_bases
AATAGAACAGTTTATTGACGGGAATTTCGTTTTCAACATTGGATAGAAAAATAATAATAAAATGATTGATTTAAAAAAAG
AGCTGAAGGAATTCAGTTCT

Product: mechanosensitive ion channel family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MSLLTYTEEFFNYVREFLLLRFLLFALVLIIISFVINRIIDWFFRKSSFFDEEVEQTIQSVIRSIFRYIIIISLIIYLIS
QFVDIKSIIAGAGIAGVVIGFAAQQMLKDVILGFARLADKEFRVGDFVTFNGTNSGTIEEISIRFMQIREWSGKLLTIPH
GEIRTIQNFNKGWMRVIERITVSYQEDPTRVKELLEEVCVNCNEKLAPSLYKVEDEAVEPFKYVGVTDLNPNLKYVGYEF
CITGLIKPEDYFETSRQVRFELMSMFHKNQVQMPAANMLVTTESLQHTHGGQSLSDS

Sequences:

>Translated_297_residues
MSLLTYTEEFFNYVREFLLLRFLLFALVLIIISFVINRIIDWFFRKSSFFDEEVEQTIQSVIRSIFRYIIIISLIIYLIS
QFVDIKSIIAGAGIAGVVIGFAAQQMLKDVILGFARLADKEFRVGDFVTFNGTNSGTIEEISIRFMQIREWSGKLLTIPH
GEIRTIQNFNKGWMRVIERITVSYQEDPTRVKELLEEVCVNCNEKLAPSLYKVEDEAVEPFKYVGVTDLNPNLKYVGYEF
CITGLIKPEDYFETSRQVRFELMSMFHKNQVQMPAANMLVTTESLQHTHGGQSLSDS
>Mature_296_residues
SLLTYTEEFFNYVREFLLLRFLLFALVLIIISFVINRIIDWFFRKSSFFDEEVEQTIQSVIRSIFRYIIIISLIIYLISQ
FVDIKSIIAGAGIAGVVIGFAAQQMLKDVILGFARLADKEFRVGDFVTFNGTNSGTIEEISIRFMQIREWSGKLLTIPHG
EIRTIQNFNKGWMRVIERITVSYQEDPTRVKELLEEVCVNCNEKLAPSLYKVEDEAVEPFKYVGVTDLNPNLKYVGYEFC
ITGLIKPEDYFETSRQVRFELMSMFHKNQVQMPAANMLVTTESLQHTHGGQSLSDS

Specific function: May play a role in resistance to osmotic downshock [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1789291, Length=190, Percent_Identity=30, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR006685
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 34316; Mature: 34185

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLTYTEEFFNYVREFLLLRFLLFALVLIIISFVINRIIDWFFRKSSFFDEEVEQTIQS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VIRSIFRYIIIISLIIYLISQFVDIKSIIAGAGIAGVVIGFAAQQMLKDVILGFARLADK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
EFRVGDFVTFNGTNSGTIEEISIRFMQIREWSGKLLTIPHGEIRTIQNFNKGWMRVIERI
CCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHCCHHHHHHHHHH
TVSYQEDPTRVKELLEEVCVNCNEKLAPSLYKVEDEAVEPFKYVGVTDLNPNLKYVGYEF
HHHCCCCHHHHHHHHHHHHCCCCCHHCCHHHHCCHHHHCCHHCCCEECCCCCCHHHHHHH
CITGLIKPEDYFETSRQVRFELMSMFHKNQVQMPAANMLVTTESLQHTHGGQSLSDS
HHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHEEEHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SLLTYTEEFFNYVREFLLLRFLLFALVLIIISFVINRIIDWFFRKSSFFDEEVEQTIQS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VIRSIFRYIIIISLIIYLISQFVDIKSIIAGAGIAGVVIGFAAQQMLKDVILGFARLADK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
EFRVGDFVTFNGTNSGTIEEISIRFMQIREWSGKLLTIPHGEIRTIQNFNKGWMRVIERI
CCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHCCHHHHHHHHHH
TVSYQEDPTRVKELLEEVCVNCNEKLAPSLYKVEDEAVEPFKYVGVTDLNPNLKYVGYEF
HHHCCCCHHHHHHHHHHHHCCCCCHHCCHHHHCCHHHHCCHHCCCEECCCCCCHHHHHHH
CITGLIKPEDYFETSRQVRFELMSMFHKNQVQMPAANMLVTTESLQHTHGGQSLSDS
HHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHEEEHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]