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The map label for this gene is yhcY [H]

Identifier: 52143192

GI number: 52143192

Start: 2164611

End: 2165729

Strand: Direct

Name: yhcY [H]

Synonym: BCZK2045

Alternate gene names: 52143192

Gene position: 2164611-2165729 (Clockwise)

Preceding gene: 52143194

Following gene: 52143191

Centisome position: 40.83

GC content: 35.66

Gene sequence:

>1119_bases
ATGAACTTTGAAGAAAAAGAGATGCATCGATTAGAAGCATTAAAAGCAATTGCTGAATTATTAAATGAAGCTACAGACTT
ACAGGACATGTTAGAAAAAGCGTTACATACATTGTTACAAGTTATGAATTTACAAACAGGGTGGATCTTTTTTATTGATG
AAAGTGGAAAGCACCGTATGCTTGTGGATGAAAACTTACCGCCAGCTCTTACGTGGCAAAAGAAGAAGCCGATGTGTGAA
GGAGACTGCTGGTGTGTAGAGCGTTTTGTGAATGGCAGATTGGAAAAAGCGACTAATATTATTGAATGTAAGCGAATAGA
GGATGCGATTGAATGTAATTGGGGAGAGACAGAAGATGTTACGCATCATGCCACAATTCCCCTTAGGTCTGGATCGGAGA
AATTTGGTCTATTAAATGTCGCCTCTCCTCAAAAAACACATTTTTCAGAGGAAGAATTGGCATTATTAGAATCGATTGCA
TTTCAAATCGGAACGACAATCCAACGTATTCAGTTAGTAGAGAAAGAGCGTAAATACGTAGTAGTAGCTGAAAGAAATCG
ACTTGCACGTGATTTACATGATTCAGTAAAACAGTTGTTGTTTTCCATTATGCTAACAGCAAAAGGTACGCTAAATATGA
CACAAGATAGAGACTTGCAAGAGATGTTGAGCTATATTGGAGAATTATCACAAGAAGCATTACAAGAGATGACACTTTTG
ATTTGGCAATTAAGACCGGAAGGATTAGAGAAAGGGTTAGCAGAAGCAATTAAAAATTACGGAAAGTTGTTAGGGATTTA
CGTGGAAGTTCGAATTGATGGAATGGTTTCAATTGGAGATGAAATAGAAGAAGTTTTATGGCGTATTAGTCAAGAAGCAA
TACATAATTGTAAAAAACATGCTTCATGTGAAAAGGTAAATGTTCTTTTGAAAATAGAAAATAAGCAGCTGTATTTTTAC
ATAGAGGATAATGGAATAGGATTTATACAAAAGCAAGTAAGAGAGTCAGCACTCGGTTTAAAAAGTATGAAGGAGCGTAT
TCAGTTATTGAATGGATCATTTCAAATAAAAACTGAGCTGAAAAAGGGTACGAAAATTGAAATTCAATTGCCGGTTTGA

Upstream 100 bases:

>100_bases
TAAAATGATTGATTTAAAAAAAGAGCTGAAGGAATTCAGTTCTTTTTAATTTGTAGAATTTAGAAATTTCTTAATGTTAT
AATGGTAGATGGTGATGAAA

Downstream 100 bases:

>100_bases
AGGGGGAAGAAGGTTGAAGATTAAATTATTACTAGTTGAGGATCATCACATCGTTCGAAGAGGACTTGTATTCTTTTTGA
AAACGAGAGAAGAATTTGAA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MNFEEKEMHRLEALKAIAELLNEATDLQDMLEKALHTLLQVMNLQTGWIFFIDESGKHRMLVDENLPPALTWQKKKPMCE
GDCWCVERFVNGRLEKATNIIECKRIEDAIECNWGETEDVTHHATIPLRSGSEKFGLLNVASPQKTHFSEEELALLESIA
FQIGTTIQRIQLVEKERKYVVVAERNRLARDLHDSVKQLLFSIMLTAKGTLNMTQDRDLQEMLSYIGELSQEALQEMTLL
IWQLRPEGLEKGLAEAIKNYGKLLGIYVEVRIDGMVSIGDEIEEVLWRISQEAIHNCKKHASCEKVNVLLKIENKQLYFY
IEDNGIGFIQKQVRESALGLKSMKERIQLLNGSFQIKTELKKGTKIEIQLPV

Sequences:

>Translated_372_residues
MNFEEKEMHRLEALKAIAELLNEATDLQDMLEKALHTLLQVMNLQTGWIFFIDESGKHRMLVDENLPPALTWQKKKPMCE
GDCWCVERFVNGRLEKATNIIECKRIEDAIECNWGETEDVTHHATIPLRSGSEKFGLLNVASPQKTHFSEEELALLESIA
FQIGTTIQRIQLVEKERKYVVVAERNRLARDLHDSVKQLLFSIMLTAKGTLNMTQDRDLQEMLSYIGELSQEALQEMTLL
IWQLRPEGLEKGLAEAIKNYGKLLGIYVEVRIDGMVSIGDEIEEVLWRISQEAIHNCKKHASCEKVNVLLKIENKQLYFY
IEDNGIGFIQKQVRESALGLKSMKERIQLLNGSFQIKTELKKGTKIEIQLPV
>Mature_372_residues
MNFEEKEMHRLEALKAIAELLNEATDLQDMLEKALHTLLQVMNLQTGWIFFIDESGKHRMLVDENLPPALTWQKKKPMCE
GDCWCVERFVNGRLEKATNIIECKRIEDAIECNWGETEDVTHHATIPLRSGSEKFGLLNVASPQKTHFSEEELALLESIA
FQIGTTIQRIQLVEKERKYVVVAERNRLARDLHDSVKQLLFSIMLTAKGTLNMTQDRDLQEMLSYIGELSQEALQEMTLL
IWQLRPEGLEKGLAEAIKNYGKLLGIYVEVRIDGMVSIGDEIEEVLWRISQEAIHNCKKHASCEKVNVLLKIENKQLYFY
IEDNGIGFIQKQVRESALGLKSMKERIQLLNGSFQIKTELKKGTKIEIQLPV

Specific function: Member of the two-component regulatory system yhcY/yhcZ. Probably activates yhcZ by phosphorylation [H]

COG id: COG2203

COG function: function code T; FOG: GAF domain

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787474, Length=243, Percent_Identity=27.5720164609054, Blast_Score=85, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR011712 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42766; Mature: 42766

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFEEKEMHRLEALKAIAELLNEATDLQDMLEKALHTLLQVMNLQTGWIFFIDESGKHRM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEE
LVDENLPPALTWQKKKPMCEGDCWCVERFVNGRLEKATNIIECKRIEDAIECNWGETEDV
EECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
THHATIPLRSGSEKFGLLNVASPQKTHFSEEELALLESIAFQIGTTIQRIQLVEKERKYV
CEEEEEEECCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
VVAERNRLARDLHDSVKQLLFSIMLTAKGTLNMTQDRDLQEMLSYIGELSQEALQEMTLL
EEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
IWQLRPEGLEKGLAEAIKNYGKLLGIYVEVRIDGMVSIGDEIEEVLWRISQEAIHNCKKH
HHHCCHHHHHHHHHHHHHHHHHHEEEEEEEEECCEEECHHHHHHHHHHHHHHHHHHHHHC
ASCEKVNVLLKIENKQLYFYIEDNGIGFIQKQVRESALGLKSMKERIQLLNGSFQIKTEL
CCCCCEEEEEEEECCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
KKGTKIEIQLPV
CCCCEEEEEECC
>Mature Secondary Structure
MNFEEKEMHRLEALKAIAELLNEATDLQDMLEKALHTLLQVMNLQTGWIFFIDESGKHRM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEE
LVDENLPPALTWQKKKPMCEGDCWCVERFVNGRLEKATNIIECKRIEDAIECNWGETEDV
EECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
THHATIPLRSGSEKFGLLNVASPQKTHFSEEELALLESIAFQIGTTIQRIQLVEKERKYV
CEEEEEEECCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
VVAERNRLARDLHDSVKQLLFSIMLTAKGTLNMTQDRDLQEMLSYIGELSQEALQEMTLL
EEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
IWQLRPEGLEKGLAEAIKNYGKLLGIYVEVRIDGMVSIGDEIEEVLWRISQEAIHNCKKH
HHHCCHHHHHHHHHHHHHHHHHHEEEEEEEEECCEEECHHHHHHHHHHHHHHHHHHHHHC
ASCEKVNVLLKIENKQLYFYIEDNGIGFIQKQVRESALGLKSMKERIQLLNGSFQIKTEL
CCCCCEEEEEEEECCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
KKGTKIEIQLPV
CCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]