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The map label for this gene is ltaS1 [H]

Identifier: 52142576

GI number: 52142576

Start: 2774398

End: 2776371

Strand: Reverse

Name: ltaS1 [H]

Synonym: BCZK2666

Alternate gene names: 52142576

Gene position: 2776371-2774398 (Counterclockwise)

Preceding gene: 52142575

Following gene: 52142579

Centisome position: 52.38

GC content: 33.74

Gene sequence:

>1974_bases
ATGAAACAATTCTTATTAAAGAGCAAAAGTGTGCTAAGCAATCATTTTGGATTCTTTCTGTTTGCCGTTATTTTATTTTG
GCTCAAAACATATGCGGCTTATGTAACAGAATTTAATTTAGGTATTTCAAATACAATCCAAAAATTCTTGTTGTTTTTCA
ACCCGCTTAGTTCAGCAGTGCTATTTTTAGGACTTGCATTATTTGCAAAAGGGAAACGATCTTATATTTGGTTAATTGTT
ATCAACTTGTTATTGTCGATTCTTTTATACGCAAACGTCGTATACTATCGCTTTTTCAGTGACTTTATTACGTTCCCGAC
ATTAACACAAACGAATAACTTTGGAGATTTAGGTGGTAGTATCGTTGCGTTGCTACATCTTTATGATCCGCTATACTTCA
TAGATACAATTATTTTAATTGTGTTAGTAGCAACGAAATTTGCAAATCCGAAACCAATTCGTGTTGCGAAACATAAATTA
TCTTTAGTATTTGTAGCAGGTATTTTATTATTCAGTGTTAACTTAGGACTTGCAGAATCTGACCGTCCTGAATTATTAAC
AAGAACATTTGACCGAAATTATATTGTGAAATATTTAGGGGCGTATAACTACACAATTTATGATGGAATTCAAAGTGCAA
AAGCATCAACGGAAAGAGCGTTAGCTGATGGAGATAATATGACAGAAGTAAGAAATTATTTAACATCAACTTACGCAAGT
CCAAACCCTGAGTATTTCGGTAAAGGTAAGGGAATGAACGTAATTTATATTCATTTAGAGTCATTCCAAAACTTCTTAAT
TGATTATAAATTAAACGGTCAAGAAGTTACGCCGTTCTTAAACTCATTTACAAAAGATGCGAATACGCTTTACTTTGATA
ACTTCTTCCATCAAACAGGACAAGGGAAAACGTCTGATGCGGAGTTTATGTTAGAGAATTCTATGTTTGGTTTACCACAA
GGATCTGTATTTACAACGAAATCTCATAACACGTATCAATCAGCACCAGCAATTTTAGGACAACAAGGATACACATCAGC
TGTATTCCATGGTAACTATAAAACATTTTGGAACCGTGACGATATTTATAAATCATTTGGTTTTAATAAATTCTTTGATG
CTTCATACTATGATATGAACGCAAAAGATGTAGTAAACTATGGATTAAAAGATAAACCATTCTTTAATGAATCCATTCCG
TTATTAGAAACATTGAAACAACCGTTCTATACGAAGTTTATTACGTTATCGAATCACTTCCCGTATCCAATTGATAAAGA
GGAAGCGACAATTGAACCAGCGAACACAGGTGACTCGTCTGTAGATACGTATTTCCAAACAGCACGTTATTTAGACGAAT
CTGTAAAAGGTTTCATCGATTACTTGAAGCAATCTGGTTTATATGATAATTCTATTATCGTTATGTACGGAGACCATTAC
GGTATTTCAGATAATCATAACGCAGCAATGTCAAAAGTAATGGGTAAAGAAATTAACTCGTTTGAAAATGCACAGTTACA
ACGTGTACCTTTAATCGTTCGTGTACCAGGTGTGAAAGGTGGCGTACAACATCAATACGGTGGTGAAATTGATGTTCTTC
CAACTCTTTTACACTTACTAGGAACAGATACAAAAAATTATGTTCAATTTGGTTCAGATTTATTATCACCAGATCATAAA
CAAGTTGTTGCGTTCCGTAACGGCAACTTCGTAAGCCCAACAGTTACTGCACTAAACGGCAAATATTATGATACAACAAC
TGGAAAACCTGTAGAATTTACAGATGAAATAAAACAAAATGAACAAATGGTTCAAAACTCGTTAAAATACTCTGACCAAG
TCGTAAATGGTGACTTATTACGATTCTACACACCGGAAGGATTTACACCGATAGATCGTTCGAAGTATAACTATAACAAT
CGTGATAAAAACAAAACGAAAGTAAAAACGGCTCTGGAAGGGGAAGCTAAATAA

Upstream 100 bases:

>100_bases
TCATATAGTTAAATAAATAAAATCTATTTGAAGATAAAAAATTGAATAGAGAGACAGACTTATAAAAAATAAGCCTTGGA
TGATCAAAAGAGGTGGAGAA

Downstream 100 bases:

>100_bases
ATAACAAAAGACACTATTCATATGAATAGTGTCTTTTGTTTGTAAATATAACATCATCATCAGATAGAACCATCTGTTGC
TTTTTGTTTTGCCTTTCCGA

Product: phosphoglycerol transferase

Products: 1,2-diacyl-sn-glycerol; membrane-derived-oligosaccharide 6-(glycerophospho)-D-glucose

Alternate protein names: LTA synthase 1; Polyglycerol phosphate synthase 1 [H]

Number of amino acids: Translated: 657; Mature: 657

Protein sequence:

>657_residues
MKQFLLKSKSVLSNHFGFFLFAVILFWLKTYAAYVTEFNLGISNTIQKFLLFFNPLSSAVLFLGLALFAKGKRSYIWLIV
INLLLSILLYANVVYYRFFSDFITFPTLTQTNNFGDLGGSIVALLHLYDPLYFIDTIILIVLVATKFANPKPIRVAKHKL
SLVFVAGILLFSVNLGLAESDRPELLTRTFDRNYIVKYLGAYNYTIYDGIQSAKASTERALADGDNMTEVRNYLTSTYAS
PNPEYFGKGKGMNVIYIHLESFQNFLIDYKLNGQEVTPFLNSFTKDANTLYFDNFFHQTGQGKTSDAEFMLENSMFGLPQ
GSVFTTKSHNTYQSAPAILGQQGYTSAVFHGNYKTFWNRDDIYKSFGFNKFFDASYYDMNAKDVVNYGLKDKPFFNESIP
LLETLKQPFYTKFITLSNHFPYPIDKEEATIEPANTGDSSVDTYFQTARYLDESVKGFIDYLKQSGLYDNSIIVMYGDHY
GISDNHNAAMSKVMGKEINSFENAQLQRVPLIVRVPGVKGGVQHQYGGEIDVLPTLLHLLGTDTKNYVQFGSDLLSPDHK
QVVAFRNGNFVSPTVTALNGKYYDTTTGKPVEFTDEIKQNEQMVQNSLKYSDQVVNGDLLRFYTPEGFTPIDRSKYNYNN
RDKNKTKVKTALEGEAK

Sequences:

>Translated_657_residues
MKQFLLKSKSVLSNHFGFFLFAVILFWLKTYAAYVTEFNLGISNTIQKFLLFFNPLSSAVLFLGLALFAKGKRSYIWLIV
INLLLSILLYANVVYYRFFSDFITFPTLTQTNNFGDLGGSIVALLHLYDPLYFIDTIILIVLVATKFANPKPIRVAKHKL
SLVFVAGILLFSVNLGLAESDRPELLTRTFDRNYIVKYLGAYNYTIYDGIQSAKASTERALADGDNMTEVRNYLTSTYAS
PNPEYFGKGKGMNVIYIHLESFQNFLIDYKLNGQEVTPFLNSFTKDANTLYFDNFFHQTGQGKTSDAEFMLENSMFGLPQ
GSVFTTKSHNTYQSAPAILGQQGYTSAVFHGNYKTFWNRDDIYKSFGFNKFFDASYYDMNAKDVVNYGLKDKPFFNESIP
LLETLKQPFYTKFITLSNHFPYPIDKEEATIEPANTGDSSVDTYFQTARYLDESVKGFIDYLKQSGLYDNSIIVMYGDHY
GISDNHNAAMSKVMGKEINSFENAQLQRVPLIVRVPGVKGGVQHQYGGEIDVLPTLLHLLGTDTKNYVQFGSDLLSPDHK
QVVAFRNGNFVSPTVTALNGKYYDTTTGKPVEFTDEIKQNEQMVQNSLKYSDQVVNGDLLRFYTPEGFTPIDRSKYNYNN
RDKNKTKVKTALEGEAK
>Mature_657_residues
MKQFLLKSKSVLSNHFGFFLFAVILFWLKTYAAYVTEFNLGISNTIQKFLLFFNPLSSAVLFLGLALFAKGKRSYIWLIV
INLLLSILLYANVVYYRFFSDFITFPTLTQTNNFGDLGGSIVALLHLYDPLYFIDTIILIVLVATKFANPKPIRVAKHKL
SLVFVAGILLFSVNLGLAESDRPELLTRTFDRNYIVKYLGAYNYTIYDGIQSAKASTERALADGDNMTEVRNYLTSTYAS
PNPEYFGKGKGMNVIYIHLESFQNFLIDYKLNGQEVTPFLNSFTKDANTLYFDNFFHQTGQGKTSDAEFMLENSMFGLPQ
GSVFTTKSHNTYQSAPAILGQQGYTSAVFHGNYKTFWNRDDIYKSFGFNKFFDASYYDMNAKDVVNYGLKDKPFFNESIP
LLETLKQPFYTKFITLSNHFPYPIDKEEATIEPANTGDSSVDTYFQTARYLDESVKGFIDYLKQSGLYDNSIIVMYGDHY
GISDNHNAAMSKVMGKEINSFENAQLQRVPLIVRVPGVKGGVQHQYGGEIDVLPTLLHLLGTDTKNYVQFGSDLLSPDHK
QVVAFRNGNFVSPTVTALNGKYYDTTTGKPVEFTDEIKQNEQMVQNSLKYSDQVVNGDLLRFYTPEGFTPIDRSKYNYNN
RDKNKTKVKTALEGEAK

Specific function: Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate, a reaction that presumably uses phosphatidylglycerol (PG) as substrate [H]

COG id: COG1368

COG function: function code M; Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily

Gene ontology:

Cell location: Processed glycerol phosphate lipoteichoic acid synthase 1:Secreted. Note=The secretion into the extracellular medium is dependent on secA and ffh [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LTA synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR012160
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: 2.7.8.20

Molecular weight: Translated: 74583; Mature: 74583

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQFLLKSKSVLSNHFGFFLFAVILFWLKTYAAYVTEFNLGISNTIQKFLLFFNPLSSAV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHH
LFLGLALFAKGKRSYIWLIVINLLLSILLYANVVYYRFFSDFITFPTLTQTNNFGDLGGS
HHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHH
IVALLHLYDPLYFIDTIILIVLVATKFANPKPIRVAKHKLSLVFVAGILLFSVNLGLAES
HHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
DRPELLTRTFDRNYIVKYLGAYNYTIYDGIQSAKASTERALADGDNMTEVRNYLTSTYAS
CCHHHHHHHCCCHHHHHHHCCCCEEEHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
PNPEYFGKGKGMNVIYIHLESFQNFLIDYKLNGQEVTPFLNSFTKDANTLYFDNFFHQTG
CCCCCCCCCCCCEEEEEEEECCCCEEEEEEECCCHHHHHHHHHCCCCCEEEEHHHHHHCC
QGKTSDAEFMLENSMFGLPQGSVFTTKSHNTYQSAPAILGQQGYTSAVFHGNYKTFWNRD
CCCCCCHHHEECCCCCCCCCCCEEEECCCCCHHHCHHHHCCCCCCEEEEECCCCEECCCH
DIYKSFGFNKFFDASYYDMNAKDVVNYGLKDKPFFNESIPLLETLKQPFYTKFITLSNHF
HHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHCCCHHEEEEEECCCC
PYPIDKEEATIEPANTGDSSVDTYFQTARYLDESVKGFIDYLKQSGLYDNSIIVMYGDHY
CCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
GISDNHNAAMSKVMGKEINSFENAQLQRVPLIVRVPGVKGGVQHQYGGEIDVLPTLLHLL
CCCCCCHHHHHHHHHHHHCCCCCCCHHHCCEEEECCCCCCCCCCCCCCCEEHHHHHHHHH
GTDTKNYVQFGSDLLSPDHKQVVAFRNGNFVSPTVTALNGKYYDTTTGKPVEFTDEIKQN
CCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCEEEECCCCCCCCHHHHHHHH
EQMVQNSLKYSDQVVNGDLLRFYTPEGFTPIDRSKYNYNNRDKNKTKVKTALEGEAK
HHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MKQFLLKSKSVLSNHFGFFLFAVILFWLKTYAAYVTEFNLGISNTIQKFLLFFNPLSSAV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHH
LFLGLALFAKGKRSYIWLIVINLLLSILLYANVVYYRFFSDFITFPTLTQTNNFGDLGGS
HHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHH
IVALLHLYDPLYFIDTIILIVLVATKFANPKPIRVAKHKLSLVFVAGILLFSVNLGLAES
HHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
DRPELLTRTFDRNYIVKYLGAYNYTIYDGIQSAKASTERALADGDNMTEVRNYLTSTYAS
CCHHHHHHHCCCHHHHHHHCCCCEEEHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
PNPEYFGKGKGMNVIYIHLESFQNFLIDYKLNGQEVTPFLNSFTKDANTLYFDNFFHQTG
CCCCCCCCCCCCEEEEEEEECCCCEEEEEEECCCHHHHHHHHHCCCCCEEEEHHHHHHCC
QGKTSDAEFMLENSMFGLPQGSVFTTKSHNTYQSAPAILGQQGYTSAVFHGNYKTFWNRD
CCCCCCHHHEECCCCCCCCCCCEEEECCCCCHHHCHHHHCCCCCCEEEEECCCCEECCCH
DIYKSFGFNKFFDASYYDMNAKDVVNYGLKDKPFFNESIPLLETLKQPFYTKFITLSNHF
HHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHCCCHHEEEEEECCCC
PYPIDKEEATIEPANTGDSSVDTYFQTARYLDESVKGFIDYLKQSGLYDNSIIVMYGDHY
CCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
GISDNHNAAMSKVMGKEINSFENAQLQRVPLIVRVPGVKGGVQHQYGGEIDVLPTLLHLL
CCCCCCHHHHHHHHHHHHCCCCCCCHHHCCEEEECCCCCCCCCCCCCCCEEHHHHHHHHH
GTDTKNYVQFGSDLLSPDHKQVVAFRNGNFVSPTVTALNGKYYDTTTGKPVEFTDEIKQN
CCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCEEEECCCCCCCCHHHHHHHH
EQMVQNSLKYSDQVVNGDLLRFYTPEGFTPIDRSKYNYNNRDKNKTKVKTALEGEAK
HHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: phosphatidylglycerol; membrane-derived-oligosaccharide D-glucose

Specific reaction: phosphatidylglycerol + membrane-derived-oligosaccharide D-glucose = 1,2-diacyl-sn-glycerol + membrane-derived-oligosaccharide 6-(glycerophospho)-D-glucose

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377; 10658653 [H]