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The map label for this gene is manR [H]

Identifier: 52142579

GI number: 52142579

Start: 2771256

End: 2773361

Strand: Reverse

Name: manR [H]

Synonym: BCZK2664

Alternate gene names: 52142579

Gene position: 2773361-2771256 (Counterclockwise)

Preceding gene: 52142576

Following gene: 52142578

Centisome position: 52.32

GC content: 30.1

Gene sequence:

>2106_bases
ATGATATTAGATACTCGAAGTATAAATATTTTGCAACAAATTATTCAAGCAGAGGATTATGTGTCTATAAATCAATTAAT
TGATTTGATTCAAGTTTCCAAACGAACGCTTTATTACGATATTAAGAAAATTGACGATTGGTTACAAGAGGAAGGATTAC
ATTCTATTGAATATATACGACACTTAGGTTATTGCTTAAATAAAGAAACGAAACAAATGATAGTAAAGAAATTAAATGAG
TGTATGAATAATCAATATGAATATTCTCCGAAAGAAAGAAAAATATGGTTAATATTATATTTACTAATACAGGAAAAAAG
AATTTTATTGAAAGACTTAATAAACCTTTTGCAGGTAAGTCGTAATACTGTACTTGCAGATTTGAAAAAGCTAAAAGTAG
AGTTGAATAAGTATAATTTATCTTTACATTCTTTTCGTAAGGAAGGCTATCAAATTGTTGGAAATGAACAGAGTAAACGA
AATTTATTAATTTTAAGCCTCTCTCAAATTATTTCTCAAAATGGCTGGGAGTATTTAATATCACAAGTAAATTATATTAT
GAGTGATATGGGAAGTGAAACAGATACACTTGCAAGAGAAACATTGTATATTATAAAAAAAATTCTTGCGAATTGTGAAG
AGTTTTTAGGTGTCCAATATACAGATGAGGTACTAGAAAATTTAAGCGTTTACATGTATTTGTTCCATAGACGTATTCTA
AAAGGTAAGTGCGTCGAGATGGAAGAAGCTGAAAAAAATGTTCTGAAAGATTCAAAGCAATTTGAAGCTGCGAAATATAT
AGCAAAGCAGTTTGAACGAGCGTTTGTTGTCAAATTTCCAATAGATGAAATCTATTATATTACGACTCATTTGCTAGGTG
CAAAAGTAAATTATCAGGAAAATGTTTATGAGAAAAATAACATGGATGAAATACATTCAATTGTTGACTGTATGATTAAA
GATTTTCAACACTATGCTTGTGTTTTATTTCAAGACTTTAATGGGTTGTTTACAGATCTATATTTGCATATGAAACCTGC
ATTTTATCGTGTGAAGTATGGAATAGAAATTGAAAACCCATTACGAAATACAATTCAAGAAAATTATGAAGAGGTATATT
TTCTTACGAAAAAGGTAATTCATCATTTTGAAGAATATGTGAGAAAATCTGTTTCCGATGATGAAATTGCGTATGTTACT
ATGCATTTTGGAGCTTGGATGAGGAAAGAGGGAATCGTTCCCAATCCACGAAAAACAGCATTACTTGTTTGTCCAAATGG
CATTGGCACATCACGTATGTTGCAGTATCAATTAGAGAAGTTATTTTCAAACATAGATATATTAAATGCAATTTCAAAAC
GGGAATATGAATCAAATACATTTGATGTAGATTGTATAATTACGACTACTGAAATTGAAAAAGGGAATGTGCCGGTTTTT
AAGGTGAACCCAATTTTATCGGATTCTGAAAAAGCAGCTCTATTAAGAAAAGTAAATGGAGTATTGTATGGAGAGAATCA
AAAAGATTCTGTGGATTTAGTGATGGGGATAATTCAAAAATATGCTGACGTAGTGGATGAAGAATCTTTAAAAAGAGAAC
TGATTGAATTTATGAGTGGTCCGGCGTATTTTGAGAAGGAGGAGAAGTATAAACCAATGTTAAACGAACTTTTAACTAGA
GAATTTATTCAGCTTGAAGATCGTGTTGATAATTGGAAAGATGCGATAAGATTAGCGGCTGATCCGTTATTACAAAATCA
ATATATCTTTGAAGAATATATCAATGAAATGATTGTAAATGTAGAAAAATTAGGTCCTTATATTGTTATTGCACCTAAAA
TTGCAATACCTCATGCTCGCCCGGAAGCAGGGGTCAAAAAATTGGGGATGAGTTTATTACAACTAAAAGAAAGTGTTCTA
TTTTCAGAAAAACAAGAGCATGCTGTAAATTTAATTATTGTATTGGCAGCGATTGATAATGAGACACACTTGAAAGCATT
AGCACAATTAAGTGAGATGTTATCAGATCCGAAAAATGTGGAAATGTTAATTCATTCAAATTCAATAGATGAAATGCTAA
AAATGATAGCTAAATATTCTAATTAA

Upstream 100 bases:

>100_bases
TATTAATAGAAAGCGATTTCAAAAAATCTAATTTTGCAAAGTTAGTATCTATACTTGCAAGTCAATTAGTGAACAAGTAT
AGAAAGGGTGTACACCAAAT

Downstream 100 bases:

>100_bases
AGGGGAGATTGAAATGAAAAAAGTATTAGTTGTATGTGGAAATGGATTAGGAAGTAGTTTTATTGTAGAAATGAATGTGA
AGAAAATTTTAAGTGAATTA

Product: BglG family transcriptional antiterminator

Products: NA

Alternate protein names: Putative phosphotransferase enzyme IIB component; Putative PTS system EIIB component; Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]

Number of amino acids: Translated: 701; Mature: 701

Protein sequence:

>701_residues
MILDTRSINILQQIIQAEDYVSINQLIDLIQVSKRTLYYDIKKIDDWLQEEGLHSIEYIRHLGYCLNKETKQMIVKKLNE
CMNNQYEYSPKERKIWLILYLLIQEKRILLKDLINLLQVSRNTVLADLKKLKVELNKYNLSLHSFRKEGYQIVGNEQSKR
NLLILSLSQIISQNGWEYLISQVNYIMSDMGSETDTLARETLYIIKKILANCEEFLGVQYTDEVLENLSVYMYLFHRRIL
KGKCVEMEEAEKNVLKDSKQFEAAKYIAKQFERAFVVKFPIDEIYYITTHLLGAKVNYQENVYEKNNMDEIHSIVDCMIK
DFQHYACVLFQDFNGLFTDLYLHMKPAFYRVKYGIEIENPLRNTIQENYEEVYFLTKKVIHHFEEYVRKSVSDDEIAYVT
MHFGAWMRKEGIVPNPRKTALLVCPNGIGTSRMLQYQLEKLFSNIDILNAISKREYESNTFDVDCIITTTEIEKGNVPVF
KVNPILSDSEKAALLRKVNGVLYGENQKDSVDLVMGIIQKYADVVDEESLKRELIEFMSGPAYFEKEEKYKPMLNELLTR
EFIQLEDRVDNWKDAIRLAADPLLQNQYIFEEYINEMIVNVEKLGPYIVIAPKIAIPHARPEAGVKKLGMSLLQLKESVL
FSEKQEHAVNLIIVLAAIDNETHLKALAQLSEMLSDPKNVEMLIHSNSIDEMLKMIAKYSN

Sequences:

>Translated_701_residues
MILDTRSINILQQIIQAEDYVSINQLIDLIQVSKRTLYYDIKKIDDWLQEEGLHSIEYIRHLGYCLNKETKQMIVKKLNE
CMNNQYEYSPKERKIWLILYLLIQEKRILLKDLINLLQVSRNTVLADLKKLKVELNKYNLSLHSFRKEGYQIVGNEQSKR
NLLILSLSQIISQNGWEYLISQVNYIMSDMGSETDTLARETLYIIKKILANCEEFLGVQYTDEVLENLSVYMYLFHRRIL
KGKCVEMEEAEKNVLKDSKQFEAAKYIAKQFERAFVVKFPIDEIYYITTHLLGAKVNYQENVYEKNNMDEIHSIVDCMIK
DFQHYACVLFQDFNGLFTDLYLHMKPAFYRVKYGIEIENPLRNTIQENYEEVYFLTKKVIHHFEEYVRKSVSDDEIAYVT
MHFGAWMRKEGIVPNPRKTALLVCPNGIGTSRMLQYQLEKLFSNIDILNAISKREYESNTFDVDCIITTTEIEKGNVPVF
KVNPILSDSEKAALLRKVNGVLYGENQKDSVDLVMGIIQKYADVVDEESLKRELIEFMSGPAYFEKEEKYKPMLNELLTR
EFIQLEDRVDNWKDAIRLAADPLLQNQYIFEEYINEMIVNVEKLGPYIVIAPKIAIPHARPEAGVKKLGMSLLQLKESVL
FSEKQEHAVNLIIVLAAIDNETHLKALAQLSEMLSDPKNVEMLIHSNSIDEMLKMIAKYSN
>Mature_701_residues
MILDTRSINILQQIIQAEDYVSINQLIDLIQVSKRTLYYDIKKIDDWLQEEGLHSIEYIRHLGYCLNKETKQMIVKKLNE
CMNNQYEYSPKERKIWLILYLLIQEKRILLKDLINLLQVSRNTVLADLKKLKVELNKYNLSLHSFRKEGYQIVGNEQSKR
NLLILSLSQIISQNGWEYLISQVNYIMSDMGSETDTLARETLYIIKKILANCEEFLGVQYTDEVLENLSVYMYLFHRRIL
KGKCVEMEEAEKNVLKDSKQFEAAKYIAKQFERAFVVKFPIDEIYYITTHLLGAKVNYQENVYEKNNMDEIHSIVDCMIK
DFQHYACVLFQDFNGLFTDLYLHMKPAFYRVKYGIEIENPLRNTIQENYEEVYFLTKKVIHHFEEYVRKSVSDDEIAYVT
MHFGAWMRKEGIVPNPRKTALLVCPNGIGTSRMLQYQLEKLFSNIDILNAISKREYESNTFDVDCIITTTEIEKGNVPVF
KVNPILSDSEKAALLRKVNGVLYGENQKDSVDLVMGIIQKYADVVDEESLKRELIEFMSGPAYFEKEEKYKPMLNELLTR
EFIQLEDRVDNWKDAIRLAADPLLQNQYIFEEYINEMIVNVEKLGPYIVIAPKIAIPHARPEAGVKKLGMSLLQLKESVL
FSEKQEHAVNLIIVLAAIDNETHLKALAQLSEMLSDPKNVEMLIHSNSIDEMLKMIAKYSN

Specific function: May regulate the expression of the mannose operon [H]

COG id: COG3711

COG function: function code K; Transcriptional antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI2367359, Length=145, Percent_Identity=32.4137931034483, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1790755, Length=145, Percent_Identity=26.8965517241379, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1789302, Length=114, Percent_Identity=35.9649122807018, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790027, Length=142, Percent_Identity=34.5070422535211, Blast_Score=73, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013196
- InterPro:   IPR007737
- InterPro:   IPR011608
- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08279 HTH_11; PF05043 Mga; PF00874 PRD; PF00359 PTS_EIIA_2 [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 81925; Mature: 81925

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILDTRSINILQQIIQAEDYVSINQLIDLIQVSKRTLYYDIKKIDDWLQEEGLHSIEYIR
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
HLGYCLNKETKQMIVKKLNECMNNQYEYSPKERKIWLILYLLIQEKRILLKDLINLLQVS
HHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNTVLADLKKLKVELNKYNLSLHSFRKEGYQIVGNEQSKRNLLILSLSQIISQNGWEYLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEEHHHHHCCCCHHHHH
SQVNYIMSDMGSETDTLARETLYIIKKILANCEEFLGVQYTDEVLENLSVYMYLFHRRIL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
KGKCVEMEEAEKNVLKDSKQFEAAKYIAKQFERAFVVKFPIDEIYYITTHLLGAKVNYQE
CCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHCCCCCCHH
NVYEKNNMDEIHSIVDCMIKDFQHYACVLFQDFNGLFTDLYLHMKPAFYRVKYGIEIENP
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEECHH
LRNTIQENYEEVYFLTKKVIHHFEEYVRKSVSDDEIAYVTMHFGAWMRKEGIVPNPRKTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHCCCCCCCCCCCE
LLVCPNGIGTSRMLQYQLEKLFSNIDILNAISKREYESNTFDVDCIITTTEIEKGNVPVF
EEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCEE
KVNPILSDSEKAALLRKVNGVLYGENQKDSVDLVMGIIQKYADVVDEESLKRELIEFMSG
EECCCCCCCHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCC
PAYFEKEEKYKPMLNELLTREFIQLEDRVDNWKDAIRLAADPLLQNQYIFEEYINEMIVN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEKLGPYIVIAPKIAIPHARPEAGVKKLGMSLLQLKESVLFSEKQEHAVNLIIVLAAIDN
HHHCCCEEEEECCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEEEEEEECCC
ETHLKALAQLSEMLSDPKNVEMLIHSNSIDEMLKMIAKYSN
HHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCC
>Mature Secondary Structure
MILDTRSINILQQIIQAEDYVSINQLIDLIQVSKRTLYYDIKKIDDWLQEEGLHSIEYIR
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
HLGYCLNKETKQMIVKKLNECMNNQYEYSPKERKIWLILYLLIQEKRILLKDLINLLQVS
HHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNTVLADLKKLKVELNKYNLSLHSFRKEGYQIVGNEQSKRNLLILSLSQIISQNGWEYLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEEHHHHHCCCCHHHHH
SQVNYIMSDMGSETDTLARETLYIIKKILANCEEFLGVQYTDEVLENLSVYMYLFHRRIL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
KGKCVEMEEAEKNVLKDSKQFEAAKYIAKQFERAFVVKFPIDEIYYITTHLLGAKVNYQE
CCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHCCCCCCHH
NVYEKNNMDEIHSIVDCMIKDFQHYACVLFQDFNGLFTDLYLHMKPAFYRVKYGIEIENP
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEECHH
LRNTIQENYEEVYFLTKKVIHHFEEYVRKSVSDDEIAYVTMHFGAWMRKEGIVPNPRKTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHCCCCCCCCCCCE
LLVCPNGIGTSRMLQYQLEKLFSNIDILNAISKREYESNTFDVDCIITTTEIEKGNVPVF
EEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCEE
KVNPILSDSEKAALLRKVNGVLYGENQKDSVDLVMGIIQKYADVVDEESLKRELIEFMSG
EECCCCCCCHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCC
PAYFEKEEKYKPMLNELLTREFIQLEDRVDNWKDAIRLAADPLLQNQYIFEEYINEMIVN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEKLGPYIVIAPKIAIPHARPEAGVKKLGMSLLQLKESVLFSEKQEHAVNLIIVLAAIDN
HHHCCCEEEEECCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEEEEEEECCC
ETHLKALAQLSEMLSDPKNVEMLIHSNSIDEMLKMIAKYSN
HHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]