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The map label for this gene is arsC [H]

Identifier: 52142346

GI number: 52142346

Start: 3027105

End: 3027509

Strand: Reverse

Name: arsC [H]

Synonym: BCZK2898

Alternate gene names: 52142346

Gene position: 3027509-3027105 (Counterclockwise)

Preceding gene: 52142343

Following gene: 52142345

Centisome position: 57.11

GC content: 38.27

Gene sequence:

>405_bases
ATGGAGAACAAAAAGACAATCTACTTTTTATGTACAGGAAATTCATGCCGAAGCCAAATGGCAGAAGCATGGGGGAAACA
ATATTTAGGGGATAAGTGGAATGTGTATTCTGCGGGAATCGAAGTACATGGAGTGAATCCAAACGCAATTAAAGCAATGA
ACGAAGTAAATATCGACATAACAAATCAAACATCAGATATAATTGATGCAAATATTTTAAATCGTGCTGATTTAGTCGTT
ACGCTTTGTAGTCATGCGGATTCTGTTTGTCCATCTACTCCGCCGGATGTGAATCGTGTTCATTGGGGATTTGATGATCC
AGCAGGAAAAGAATGGTCTGAATTTCAACGTGTTCGTGATGAAATTGGTGAACGTATAAAACGATTTTCTGAAACAGGGG
AGTAA

Upstream 100 bases:

>100_bases
TACCTGTCATGATTGCACTTGTAAACGTTGCTTTTTGGTTTAAACGTAAATATTTTAATGATCAATCAGTCTAAATTTAA
AAATAAAGGTGGAAAACAAC

Downstream 100 bases:

>100_bases
ATAAAGGAAAGAGTCAATCTTCTATTGTGTTGGAGATTGGCTCTTTTTTATTATATATTTCATTGGTTTAAAACAACTAT
TAAAAATAATAGAGAATATT

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenate reductase 2; Arsenical pump modifier 2; Low molecular weight protein-tyrosine-phosphatase 2 [H]

Number of amino acids: Translated: 134; Mature: 134

Protein sequence:

>134_residues
MENKKTIYFLCTGNSCRSQMAEAWGKQYLGDKWNVYSAGIEVHGVNPNAIKAMNEVNIDITNQTSDIIDANILNRADLVV
TLCSHADSVCPSTPPDVNRVHWGFDDPAGKEWSEFQRVRDEIGERIKRFSETGE

Sequences:

>Translated_134_residues
MENKKTIYFLCTGNSCRSQMAEAWGKQYLGDKWNVYSAGIEVHGVNPNAIKAMNEVNIDITNQTSDIIDANILNRADLVV
TLCSHADSVCPSTPPDVNRVHWGFDDPAGKEWSEFQRVRDEIGERIKRFSETGE
>Mature_134_residues
MENKKTIYFLCTGNSCRSQMAEAWGKQYLGDKWNVYSAGIEVHGVNPNAIKAMNEVNIDITNQTSDIIDANILNRADLVV
TLCSHADSVCPSTPPDVNRVHWGFDDPAGKEWSEFQRVRDEIGERIKRFSETGE

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 15078; Mature: 15078

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENKKTIYFLCTGNSCRSQMAEAWGKQYLGDKWNVYSAGIEVHGVNPNAIKAMNEVNIDI
CCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEECCEEEECCCCHHHHHHHHCCEEE
TNQTSDIIDANILNRADLVVTLCSHADSVCPSTPPDVNRVHWGFDDPAGKEWSEFQRVRD
CCCCCHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHH
EIGERIKRFSETGE
HHHHHHHHHHHCCC
>Mature Secondary Structure
MENKKTIYFLCTGNSCRSQMAEAWGKQYLGDKWNVYSAGIEVHGVNPNAIKAMNEVNIDI
CCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEECCEEEECCCCHHHHHHHHCCEEE
TNQTSDIIDANILNRADLVVTLCSHADSVCPSTPPDVNRVHWGFDDPAGKEWSEFQRVRD
CCCCCHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHH
EIGERIKRFSETGE
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA