Click here to switch to the map view.

The map label for this gene is g6pD [H]

Identifier: 52142157

GI number: 52142157

Start: 3214341

End: 3214889

Strand: Reverse

Name: g6pD [H]

Synonym: BCZK3084

Alternate gene names: 52142157

Gene position: 3214889-3214341 (Counterclockwise)

Preceding gene: 52142158

Following gene: 52142159

Centisome position: 60.65

GC content: 32.06

Gene sequence:

>549_bases
ATGGATTCAATGACATTTCTTTTATTTGGAGCGACAGGGGATTTAGCGAAACGCAAAATTTACCCTGCTTTATACAAATT
ATTTAGTAATGGGAATATAACGCAATCTATTTCGATTATCGGTATTGGTAGAAGGGTAATGTCAGATGTGGAATTTCAAA
CAAAGGTAGAACAATCCCTTGCTACATTTTCTAGAAGATCTACTGATGACGAATTAGGAGTAGAAGAATTTATTAGCACA
TTTCGTTATTGTCAATTAAATACAGTAAATATAGAGGACTATCAAGATTTGTTGAGTCTTGTAAAGAGACGTGAAACAGA
ATTAAACATTCCTGAAAACCGCATGTTTTACCTATCTGTTATACCAGAAGTATTTGATGTCATTGCTTTAAATATTAAGG
AAATTGGATTGTGGGCTACAAAAGGATTGAAACGTCTTATTATAGAGAAGCCTTTTGCTCATCATGTAACGTCTGCTCAC
GAGTTTAACGAAAAATTAATTGAAGATTTTGATGAAACTGATATTTTTTATATCGATCATTATCTTTGA

Upstream 100 bases:

>100_bases
AACATTGGTAAAGTATGAGGTTTTAGAGACAGTATTGTGCTAAGTAGCGAATGAGTTTATATATTCTATTCTAGCAATTG
TTTTAAAAGGGAGAGAACAA

Downstream 100 bases:

>100_bases
AAATGAGTGGTAACTAAGGATAAACTTAGAAAAGTAATACGAAATAAGTAGTATGTAATTTAAGACATTTTTATTGACGA
TAATAATATATGTGGTTAAT

Product: glucose-6-phosphate dehydrogenase

Products: NA

Alternate protein names: G6PD; Vegetative protein 11; VEG11 [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MDSMTFLLFGATGDLAKRKIYPALYKLFSNGNITQSISIIGIGRRVMSDVEFQTKVEQSLATFSRRSTDDELGVEEFIST
FRYCQLNTVNIEDYQDLLSLVKRRETELNIPENRMFYLSVIPEVFDVIALNIKEIGLWATKGLKRLIIEKPFAHHVTSAH
EFNEKLIEDFDETDIFYIDHYL

Sequences:

>Translated_182_residues
MDSMTFLLFGATGDLAKRKIYPALYKLFSNGNITQSISIIGIGRRVMSDVEFQTKVEQSLATFSRRSTDDELGVEEFIST
FRYCQLNTVNIEDYQDLLSLVKRRETELNIPENRMFYLSVIPEVFDVIALNIKEIGLWATKGLKRLIIEKPFAHHVTSAH
EFNEKLIEDFDETDIFYIDHYL
>Mature_182_residues
MDSMTFLLFGATGDLAKRKIYPALYKLFSNGNITQSISIIGIGRRVMSDVEFQTKVEQSLATFSRRSTDDELGVEEFIST
FRYCQLNTVNIEDYQDLLSLVKRRETELNIPENRMFYLSVIPEVFDVIALNIKEIGLWATKGLKRLIIEKPFAHHVTSAH
EFNEKLIEDFDETDIFYIDHYL

Specific function: Pentose phosphate pathway; first step. [C]

COG id: COG0364

COG function: function code G; Glucose-6-phosphate 1-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-6-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI109389365, Length=181, Percent_Identity=30.939226519337, Blast_Score=97, Evalue=7e-21,
Organism=Homo sapiens, GI108773793, Length=181, Percent_Identity=30.939226519337, Blast_Score=97, Evalue=7e-21,
Organism=Homo sapiens, GI52145310, Length=188, Percent_Identity=28.7234042553192, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1788158, Length=179, Percent_Identity=28.4916201117318, Blast_Score=91, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17538218, Length=178, Percent_Identity=34.8314606741573, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6324088, Length=177, Percent_Identity=35.0282485875706, Blast_Score=104, Evalue=7e-24,
Organism=Drosophila melanogaster, GI221513548, Length=182, Percent_Identity=32.4175824175824, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24643352, Length=180, Percent_Identity=30, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24643350, Length=180, Percent_Identity=30, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001282
- InterPro:   IPR019796
- InterPro:   IPR022675
- InterPro:   IPR022674
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02781 G6PD_C; PF00479 G6PD_N [H]

EC number: =1.1.1.49 [H]

Molecular weight: Translated: 21130; Mature: 21130

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSMTFLLFGATGDLAKRKIYPALYKLFSNGNITQSISIIGIGRRVMSDVEFQTKVEQSL
CCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEECHHHHHHHHHHHHHHHHH
ATFSRRSTDDELGVEEFISTFRYCQLNTVNIEDYQDLLSLVKRRETELNIPENRMFYLSV
HHHHHCCCCCCCCHHHHHHHHHHHCCEECCHHHHHHHHHHHHHHCCCCCCCCCCEEHHHH
IPEVFDVIALNIKEIGLWATKGLKRLIIEKPFAHHVTSAHEFNEKLIEDFDETDIFYIDH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
YL
CC
>Mature Secondary Structure
MDSMTFLLFGATGDLAKRKIYPALYKLFSNGNITQSISIIGIGRRVMSDVEFQTKVEQSL
CCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEECHHHHHHHHHHHHHHHHH
ATFSRRSTDDELGVEEFISTFRYCQLNTVNIEDYQDLLSLVKRRETELNIPENRMFYLSV
HHHHHCCCCCCCCHHHHHHHHHHHCCEECCHHHHHHHHHHHHHHCCCCCCCCCCEEHHHH
IPEVFDVIALNIKEIGLWATKGLKRLIIEKPFAHHVTSAHEFNEKLIEDFDETDIFYIDH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
YL
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9298659 [H]