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The map label for this gene is dppE [H]

Identifier: 52141953

GI number: 52141953

Start: 3421409

End: 3423115

Strand: Reverse

Name: dppE [H]

Synonym: BCZK3291

Alternate gene names: 52141953

Gene position: 3423115-3421409 (Counterclockwise)

Preceding gene: 52141951

Following gene: 52141952

Centisome position: 64.58

GC content: 35.09

Gene sequence:

>1707_bases
ATGAAGAAAAAGATGAAAAAGTTTACGGCGGTTGTAGCACCAGTTTTAGCGATGAGTATGGCGTTAACAGCGTGTTCTGG
ATCTTCAGGTGGGGAGAAGAAAACGACAACGACATCTAATAATGGTGGAGAAGAGAAGAAATCTGATATTAAATATGCGG
CAAAGCAAGTGCTAAATCGTACAGAAACGAATGAAATTCCGACGATGGATACTTCAAAAAATACAGATACACTTGGCTCA
CAAATTTTAGGGAATACAATGGAAGGTTTATATCGATTAGATAAAGATAATAAGCCAATCCCAGCTGTAGCGGAATCTAG
CACAAAAAGCGAGGATGGCAAAAAATATACATTTAAATTACGGAAAGATGCAAAATGGTCAAATGGTGATCCTGTAACAG
CGAAAGATTTCGTATTTGCATGGCAACGTCTAGTAGATCCAAAAACAGCTGCTGAGTATGCATTTATTGCTTACTATCTT
AAAAATGCAGAAGCGATTAATCAAGGAAAAGGAGAAGTTTCGACATTAGGTGTAAAAGCGGTAGATGATTATACGCTTGA
AGTAGAACTAGAAAGACCTGTACCATATTTCTTGAACTTAATGGCATTTGCGTCATACTATCCATTAAATGAAAAGTTCG
TAAAAGAAAAAGGAAATAAATTCGGTTTAGAGTCTGATACAACACTGTATAATGGTCCATTTGTGCTTACAGACTGGAAA
CATGAGCAAGGCTGGAAACTAAAGAAAAATGATCAGTATTGGGATAAAAAGACTGTAAAACTAGAGGAAATCAACTATAG
TGTAGTAAAAGAACCAGCTACTAGAGTAAATTTATATGATACAGGTGCAATTGATTTCGCGCTATTATCAGGTGAATTCG
TGGATAAGTATAGAAACAATAAAGAAGAGTTTGGGGCCTATTCGGAAACAAGTACGTTTTACTTACGCCTCAATCAAAAA
CGTGGTGGGCAAGATACACCTCTAAAGAGTAAAAAATTACGTGAAGCAATTGCGCTATCAATTGATAAGAAAGCTTTAAC
GAATGTCATTTTAAATGATGGTTCAAAACCAGTGGATTATTTAGTACCAAAAGGTTTAGCAAGTGGACCAGACGGTAAAG
ATTTCGCAGAAACGTTTAAGAATGGTTTAAAACAAGACTCCAAAAAGGCAGCAGCAGCATGGGAAGAAGCGAAAAAAGAA
CTTGGAAAAGATCAAGTGACAATAGAGTTATTAAATTATGATACTGGTAATGCGAAAAAAGTTGGGGAGTATGTAAAAGA
TCAAGTTGAAAAGAATTTAAAAGGTGTGACAGTAAATATTAAGTTGCAACCATTTAAGCAAAAACTAAAATTAGAATCAG
ACCAAGATTATGATTTTTCATATGGTGGCTGGAATCCAGATTATGCGGATCCAATGACATATCTTGATATGTTTGAAACA
AAAAATTCGCAAAACCAGATGAGCTACTCAAATTCAAAATATGATGACGTCATTAATAAAAGTAAGACAGAATGGATGGC
TGATGCAAAAAAACGTTGGACAGAATTAGGGAAGGCAGAGAAATTGTTACTTGAGGAAGATGTAGCACTTGTACCTTTAT
ATCAAAGTGCTAAATCATATGTTATGAAACCGAATGTAAAGGGAATTGTGAAACATAATATTAGTCCGGAATATAGCTTT
AAATGGGCGTATGTAGAAGAGAAATAA

Upstream 100 bases:

>100_bases
AAAAATTAGTAGAATAATAATTAGTAATAATTTTCTGATAATTTAAATTAGAAATCTCTCAAAGTTAGTTTCGTACATAT
AAATTGGGGAGGGTACAAAA

Downstream 100 bases:

>100_bases
AAAAGAGAAGAGCATTTTCAAGTTGCTGTATAGCACTTGGAAATGCTTTTTTACGTGCACGATTTTTTGATGGGTGAATA
TATGTATTATAGAAAATTTA

Product: methyltransferase

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 568; Mature: 568

Protein sequence:

>568_residues
MKKKMKKFTAVVAPVLAMSMALTACSGSSGGEKKTTTTSNNGGEEKKSDIKYAAKQVLNRTETNEIPTMDTSKNTDTLGS
QILGNTMEGLYRLDKDNKPIPAVAESSTKSEDGKKYTFKLRKDAKWSNGDPVTAKDFVFAWQRLVDPKTAAEYAFIAYYL
KNAEAINQGKGEVSTLGVKAVDDYTLEVELERPVPYFLNLMAFASYYPLNEKFVKEKGNKFGLESDTTLYNGPFVLTDWK
HEQGWKLKKNDQYWDKKTVKLEEINYSVVKEPATRVNLYDTGAIDFALLSGEFVDKYRNNKEEFGAYSETSTFYLRLNQK
RGGQDTPLKSKKLREAIALSIDKKALTNVILNDGSKPVDYLVPKGLASGPDGKDFAETFKNGLKQDSKKAAAAWEEAKKE
LGKDQVTIELLNYDTGNAKKVGEYVKDQVEKNLKGVTVNIKLQPFKQKLKLESDQDYDFSYGGWNPDYADPMTYLDMFET
KNSQNQMSYSNSKYDDVINKSKTEWMADAKKRWTELGKAEKLLLEEDVALVPLYQSAKSYVMKPNVKGIVKHNISPEYSF
KWAYVEEK

Sequences:

>Translated_568_residues
MKKKMKKFTAVVAPVLAMSMALTACSGSSGGEKKTTTTSNNGGEEKKSDIKYAAKQVLNRTETNEIPTMDTSKNTDTLGS
QILGNTMEGLYRLDKDNKPIPAVAESSTKSEDGKKYTFKLRKDAKWSNGDPVTAKDFVFAWQRLVDPKTAAEYAFIAYYL
KNAEAINQGKGEVSTLGVKAVDDYTLEVELERPVPYFLNLMAFASYYPLNEKFVKEKGNKFGLESDTTLYNGPFVLTDWK
HEQGWKLKKNDQYWDKKTVKLEEINYSVVKEPATRVNLYDTGAIDFALLSGEFVDKYRNNKEEFGAYSETSTFYLRLNQK
RGGQDTPLKSKKLREAIALSIDKKALTNVILNDGSKPVDYLVPKGLASGPDGKDFAETFKNGLKQDSKKAAAAWEEAKKE
LGKDQVTIELLNYDTGNAKKVGEYVKDQVEKNLKGVTVNIKLQPFKQKLKLESDQDYDFSYGGWNPDYADPMTYLDMFET
KNSQNQMSYSNSKYDDVINKSKTEWMADAKKRWTELGKAEKLLLEEDVALVPLYQSAKSYVMKPNVKGIVKHNISPEYSF
KWAYVEEK
>Mature_568_residues
MKKKMKKFTAVVAPVLAMSMALTACSGSSGGEKKTTTTSNNGGEEKKSDIKYAAKQVLNRTETNEIPTMDTSKNTDTLGS
QILGNTMEGLYRLDKDNKPIPAVAESSTKSEDGKKYTFKLRKDAKWSNGDPVTAKDFVFAWQRLVDPKTAAEYAFIAYYL
KNAEAINQGKGEVSTLGVKAVDDYTLEVELERPVPYFLNLMAFASYYPLNEKFVKEKGNKFGLESDTTLYNGPFVLTDWK
HEQGWKLKKNDQYWDKKTVKLEEINYSVVKEPATRVNLYDTGAIDFALLSGEFVDKYRNNKEEFGAYSETSTFYLRLNQK
RGGQDTPLKSKKLREAIALSIDKKALTNVILNDGSKPVDYLVPKGLASGPDGKDFAETFKNGLKQDSKKAAAAWEEAKKE
LGKDQVTIELLNYDTGNAKKVGEYVKDQVEKNLKGVTVNIKLQPFKQKLKLESDQDYDFSYGGWNPDYADPMTYLDMFET
KNSQNQMSYSNSKYDDVINKSKTEWMADAKKRWTELGKAEKLLLEEDVALVPLYQSAKSYVMKPNVKGIVKHNISPEYSF
KWAYVEEK

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787495, Length=510, Percent_Identity=31.3725490196078, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI87081878, Length=537, Percent_Identity=28.4916201117318, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1789397, Length=507, Percent_Identity=28.0078895463511, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI1787762, Length=460, Percent_Identity=25.8695652173913, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1787052, Length=499, Percent_Identity=25.8517034068136, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1789887, Length=336, Percent_Identity=26.4880952380952, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789966, Length=485, Percent_Identity=25.1546391752577, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 64177; Mature: 64177

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKMKKFTAVVAPVLAMSMALTACSGSSGGEKKTTTTSNNGGEEKKSDIKYAAKQVLNR
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
TETNEIPTMDTSKNTDTLGSQILGNTMEGLYRLDKDNKPIPAVAESSTKSEDGKKYTFKL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCEEEEEE
RKDAKWSNGDPVTAKDFVFAWQRLVDPKTAAEYAFIAYYLKNAEAINQGKGEVSTLGVKA
ECCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHCCCCCEEEEEEEE
VDDYTLEVELERPVPYFLNLMAFASYYPLNEKFVKEKGNKFGLESDTTLYNGPFVLTDWK
ECCEEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCEEECCCEEEECCC
HEQGWKLKKNDQYWDKKTVKLEEINYSVVKEPATRVNLYDTGAIDFALLSGEFVDKYRNN
CCCCCCCCCCCCCCCCCCEEEECCCHHHHCCCCCEEEEEECCCEEEEECCCHHHHHHCCC
KEEFGAYSETSTFYLRLNQKRGGQDTPLKSKKLREAIALSIDKKALTNVILNDGSKPVDY
HHHCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHH
LVPKGLASGPDGKDFAETFKNGLKQDSKKAAAAWEEAKKELGKDQVTIELLNYDTGNAKK
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHH
VGEYVKDQVEKNLKGVTVNIKLQPFKQKLKLESDQDYDFSYGGWNPDYADPMTYLDMFET
HHHHHHHHHHCCCCEEEEEEEECCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHC
KNSQNQMSYSNSKYDDVINKSKTEWMADAKKRWTELGKAEKLLLEEDVALVPLYQSAKSY
CCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHCCCEEEEEHHHHHHE
VMKPNVKGIVKHNISPEYSFKWAYVEEK
EECCCCCCCEECCCCCCCEEEEEEEECC
>Mature Secondary Structure
MKKKMKKFTAVVAPVLAMSMALTACSGSSGGEKKTTTTSNNGGEEKKSDIKYAAKQVLNR
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
TETNEIPTMDTSKNTDTLGSQILGNTMEGLYRLDKDNKPIPAVAESSTKSEDGKKYTFKL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCEEEEEE
RKDAKWSNGDPVTAKDFVFAWQRLVDPKTAAEYAFIAYYLKNAEAINQGKGEVSTLGVKA
ECCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHCCCCCEEEEEEEE
VDDYTLEVELERPVPYFLNLMAFASYYPLNEKFVKEKGNKFGLESDTTLYNGPFVLTDWK
ECCEEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCEEECCCEEEECCC
HEQGWKLKKNDQYWDKKTVKLEEINYSVVKEPATRVNLYDTGAIDFALLSGEFVDKYRNN
CCCCCCCCCCCCCCCCCCEEEECCCHHHHCCCCCEEEEEECCCEEEEECCCHHHHHHCCC
KEEFGAYSETSTFYLRLNQKRGGQDTPLKSKKLREAIALSIDKKALTNVILNDGSKPVDY
HHHCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHH
LVPKGLASGPDGKDFAETFKNGLKQDSKKAAAAWEEAKKELGKDQVTIELLNYDTGNAKK
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHH
VGEYVKDQVEKNLKGVTVNIKLQPFKQKLKLESDQDYDFSYGGWNPDYADPMTYLDMFET
HHHHHHHHHHCCCCEEEEEEEECCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHC
KNSQNQMSYSNSKYDDVINKSKTEWMADAKKRWTELGKAEKLLLEEDVALVPLYQSAKSY
CCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHCCCEEEEEHHHHHHE
VMKPNVKGIVKHNISPEYSFKWAYVEEK
EECCCCCCCEECCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]