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The map label for this gene is bioD [H]

Identifier: 52141376

GI number: 52141376

Start: 3999477

End: 4000205

Strand: Reverse

Name: bioD [H]

Synonym: BCZK3874

Alternate gene names: 52141376

Gene position: 4000205-3999477 (Counterclockwise)

Preceding gene: 52141374

Following gene: 52141375

Centisome position: 75.46

GC content: 39.09

Gene sequence:

>729_bases
ATGAGCGGTTTTTTTATAACAGCAACAGATACTGAAGTTGGGAAAACTGTAGTTGCCGGTGCATTAGCCGGTGTATTTAG
AGAATTGGGATATAACATCGGGGTATATAAACCGTTGCAAAGTGGACATGTTGCATCAAATCCAGAGGGAGATGCAGCAA
GGCTAAAAGCATTATCAGGTGTACCGACAAAAGAAGATGAAATTTGCCCTTATTCTATTGAAGAGCCGCTTGCCCCGAGA
CTTGCCATGAAAAGAGCTGGAAGGACAGTAACGTTAAAAGACATTATTCACCACTATAATGAGCGATTGAAAGAGTTTAA
TAGCCTATTTGTAGAAGGAGCAGGTGGATTAGCTGTTCCGTATACAGAGGACGCTTTAGTAATTGATTTCGCAAAAGAAT
TACAGCTTCCACTTATTGTAGTAGCACGCCCTACATTAGGAACAGTAAATCATACAGTTTTAACGATTGCTTATGCAAAG
GCACATGGCTTAACAGTAGCAGGTGTCATTTTATCTGGCTGTAAAGAATGCGAAATGGAAAGGGTACAAGAAAATAAAGT
AATGATTGAAGAGCTAAGCGGGGTACCGGTTTTAGGCTTATTACCATTCTTTGAAGGTGAGTTTACAAAAAAAGAAGTAT
TGGAATCTGCTAAAGAATATATAATGATTTCAAAATTAGAGGAGTGCATCCGAAATGAATCAACCGTGGCGCACACATCT
TCAAACTAA

Upstream 100 bases:

>100_bases
CGATTGTATTTATGCCTCCCCTTGCTTCTACAATTGATGAGATTGATGAGATGTTACGTATTTTATATAAAGCAATCTCG
GATATTACGGAGGGAGAATA

Downstream 100 bases:

>100_bases
ATTACAACAATTACATGAGCAAGGGCAGTATCGCAATTTGCATGTAACAGAACAAGCAGAAGAGACATGGCTTATTCGAG
ATGAGAAAAGGATGCTAAAT

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MSGFFITATDTEVGKTVVAGALAGVFRELGYNIGVYKPLQSGHVASNPEGDAARLKALSGVPTKEDEICPYSIEEPLAPR
LAMKRAGRTVTLKDIIHHYNERLKEFNSLFVEGAGGLAVPYTEDALVIDFAKELQLPLIVVARPTLGTVNHTVLTIAYAK
AHGLTVAGVILSGCKECEMERVQENKVMIEELSGVPVLGLLPFFEGEFTKKEVLESAKEYIMISKLEECIRNESTVAHTS
SN

Sequences:

>Translated_242_residues
MSGFFITATDTEVGKTVVAGALAGVFRELGYNIGVYKPLQSGHVASNPEGDAARLKALSGVPTKEDEICPYSIEEPLAPR
LAMKRAGRTVTLKDIIHHYNERLKEFNSLFVEGAGGLAVPYTEDALVIDFAKELQLPLIVVARPTLGTVNHTVLTIAYAK
AHGLTVAGVILSGCKECEMERVQENKVMIEELSGVPVLGLLPFFEGEFTKKEVLESAKEYIMISKLEECIRNESTVAHTS
SN
>Mature_241_residues
SGFFITATDTEVGKTVVAGALAGVFRELGYNIGVYKPLQSGHVASNPEGDAARLKALSGVPTKEDEICPYSIEEPLAPRL
AMKRAGRTVTLKDIIHHYNERLKEFNSLFVEGAGGLAVPYTEDALVIDFAKELQLPLIVVARPTLGTVNHTVLTIAYAKA
HGLTVAGVILSGCKECEMERVQENKVMIEELSGVPVLGLLPFFEGEFTKKEVLESAKEYIMISKLEECIRNESTVAHTSS
N

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=205, Percent_Identity=31.219512195122, Blast_Score=97, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6324385, Length=182, Percent_Identity=34.6153846153846, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 26266; Mature: 26134

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGFFITATDTEVGKTVVAGALAGVFRELGYNIGVYKPLQSGHVASNPEGDAARLKALSG
CCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCHHHHHHHHCC
VPTKEDEICPYSIEEPLAPRLAMKRAGRTVTLKDIIHHYNERLKEFNSLFVEGAGGLAVP
CCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHEEECCCCEECC
YTEDALVIDFAKELQLPLIVVARPTLGTVNHTVLTIAYAKAHGLTVAGVILSGCKECEME
CCCCEEEEEEHHHCCCCEEEEECCCCCCCCCEEEEEEEHHHCCCHHHHHHHHHHHHHHHH
RVQENKVMIEELSGVPVLGLLPFFEGEFTKKEVLESAKEYIMISKLEECIRNESTVAHTS
HHHHHHHHHHHHCCCCEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
SN
CC
>Mature Secondary Structure 
SGFFITATDTEVGKTVVAGALAGVFRELGYNIGVYKPLQSGHVASNPEGDAARLKALSG
CCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCHHHHHHHHCC
VPTKEDEICPYSIEEPLAPRLAMKRAGRTVTLKDIIHHYNERLKEFNSLFVEGAGGLAVP
CCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHEEECCCCEECC
YTEDALVIDFAKELQLPLIVVARPTLGTVNHTVLTIAYAKAHGLTVAGVILSGCKECEME
CCCCEEEEEEHHHCCCCEEEEECCCCCCCCCEEEEEEEHHHCCCHHHHHHHHHHHHHHHH
RVQENKVMIEELSGVPVLGLLPFFEGEFTKKEVLESAKEYIMISKLEECIRNESTVAHTS
HHHHHHHHHHHHCCCCEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
SN
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA