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The map label for this gene is pbuX [H]

Identifier: 52140653

GI number: 52140653

Start: 4688591

End: 4689898

Strand: Direct

Name: pbuX [H]

Synonym: BCZK4601

Alternate gene names: 52140653

Gene position: 4688591-4689898 (Clockwise)

Preceding gene: 52140663

Following gene: 52140651

Centisome position: 88.45

GC content: 37.92

Gene sequence:

>1308_bases
ATGGAGAAACAAAGGTTTTCCGGTGCTTTAAGCATATTTCAATGGTTCTTTTTCCTGCTGGCCACTTCTGTTGCATTACC
AATCGTAATTGGTGGAGTATTTCATTTATCGATTAAGGAAATATCTGATTTGATGCAACGAACCTTTTTTGTGGTGGGCA
TTAGCTCTTTTATACAAGGTTGTTTCGGGCATCGTTATCCGATCGCAGACGGACCTGCAGGTTCCTGGGTTAGCGTATTT
GTCATTTTAGCAGGTATGGCAATGCAGCAAGGGGAAAGTACAACAGAAACATTACGACTTTTAGAAGGAGGGTTACTAGT
TACAGGATTTTTACTAATTATCCTTGGTATAACTGGCTTGTTTAACCGTCTAATGTTCTTGTTCACTCCTTTAGTTACTG
GTTCTTTTCTATTGATTCTAAGTCTTCAACTTAGTGGTGTTTTTTTAGAAGGAATGTTTGGCATACAAGGGCAATCCAGC
CTAGATTATCAAGTAGCAGCAATTTCATTTGGTGTATTTGTTCTAGTGATAGTGCTATCAATTAAAGGAAAAGGGTGGGT
GAGAAGTTACTCCGTACTGTTAGGAATTCTATTTGGGTGGTTACTATATTTCTTATTAGGAAAAAACTCCACTATGATTT
CTACACCAGCTTCCTTCATTAAATTACCAGATATTTTTGCATGGGGGACTCCGCAATTAAATGCTGGCATGGTTATAACC
TCAATTATATTTACATTTATTTTAGTCTCTAATACGGTAGCAGCTGTTACGGCTGTAAAACAGGTAGTTCCAGAATCAGA
CGCATCCGAAAAACAGACTATGAACCGCGCCAGTTGGGCAGGCGGTATTACCCATGTCATATCAGCACTTTTTTCAACAA
TTGGAATTGTACCCTTACCAGTATCGGCGGGTCTTATCAAATTAACTGGACAAAAACGAATTATGCCCTTCCTAATAGCA
AGTTTAGCTTTAGCAGGTATAGCCTTAGTTCCGTCAATCGTAAACTTTTTAGCTATGCTTCCTGGTCCTGTTGCTTGTGC
TGCAAGTTTAGCATCCTTTGTCCAAATGATAGGAATCTCATTTCAATCCCTTTTGAAGGACGAATTAGATCAACGTCGAC
TGACTATATTAGGAATCACATTGTTAATCGGTATGGGAGTAATGTTTCTTCCTAAAGAAATATTTTCTAGTCTACCTACT
ATTCTTCAATATATTTTAAGCAACGGGCTCATCGTTGGTACGATTATCGTAATTATGCTAGAACAACTATGGAAAACAAA
AAAAGCGAGCGAAAAAAATCATGTTTAA

Upstream 100 bases:

>100_bases
AAGCTTTGTTTGCGGGAGTTTTTTATTATTAAACCCATTAGAACTAATTTCTATATGGTACTTGAAAAAAAACAAATATT
TTATATGAAGGGGAAACAAT

Downstream 100 bases:

>100_bases
TTTTTAAGGGAGGGTTTCTAAATGAGTCACAAAGAATTTATGAAATTAGCAATAGATTTAGCTTACAACAATACAAAAAA
TGAAAAAGGGAAACCATTTG

Product: xanthine/uracil permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MEKQRFSGALSIFQWFFFLLATSVALPIVIGGVFHLSIKEISDLMQRTFFVVGISSFIQGCFGHRYPIADGPAGSWVSVF
VILAGMAMQQGESTTETLRLLEGGLLVTGFLLIILGITGLFNRLMFLFTPLVTGSFLLILSLQLSGVFLEGMFGIQGQSS
LDYQVAAISFGVFVLVIVLSIKGKGWVRSYSVLLGILFGWLLYFLLGKNSTMISTPASFIKLPDIFAWGTPQLNAGMVIT
SIIFTFILVSNTVAAVTAVKQVVPESDASEKQTMNRASWAGGITHVISALFSTIGIVPLPVSAGLIKLTGQKRIMPFLIA
SLALAGIALVPSIVNFLAMLPGPVACAASLASFVQMIGISFQSLLKDELDQRRLTILGITLLIGMGVMFLPKEIFSSLPT
ILQYILSNGLIVGTIIVIMLEQLWKTKKASEKNHV

Sequences:

>Translated_435_residues
MEKQRFSGALSIFQWFFFLLATSVALPIVIGGVFHLSIKEISDLMQRTFFVVGISSFIQGCFGHRYPIADGPAGSWVSVF
VILAGMAMQQGESTTETLRLLEGGLLVTGFLLIILGITGLFNRLMFLFTPLVTGSFLLILSLQLSGVFLEGMFGIQGQSS
LDYQVAAISFGVFVLVIVLSIKGKGWVRSYSVLLGILFGWLLYFLLGKNSTMISTPASFIKLPDIFAWGTPQLNAGMVIT
SIIFTFILVSNTVAAVTAVKQVVPESDASEKQTMNRASWAGGITHVISALFSTIGIVPLPVSAGLIKLTGQKRIMPFLIA
SLALAGIALVPSIVNFLAMLPGPVACAASLASFVQMIGISFQSLLKDELDQRRLTILGITLLIGMGVMFLPKEIFSSLPT
ILQYILSNGLIVGTIIVIMLEQLWKTKKASEKNHV
>Mature_435_residues
MEKQRFSGALSIFQWFFFLLATSVALPIVIGGVFHLSIKEISDLMQRTFFVVGISSFIQGCFGHRYPIADGPAGSWVSVF
VILAGMAMQQGESTTETLRLLEGGLLVTGFLLIILGITGLFNRLMFLFTPLVTGSFLLILSLQLSGVFLEGMFGIQGQSS
LDYQVAAISFGVFVLVIVLSIKGKGWVRSYSVLLGILFGWLLYFLLGKNSTMISTPASFIKLPDIFAWGTPQLNAGMVIT
SIIFTFILVSNTVAAVTAVKQVVPESDASEKQTMNRASWAGGITHVISALFSTIGIVPLPVSAGLIKLTGQKRIMPFLIA
SLALAGIALVPSIVNFLAMLPGPVACAASLASFVQMIGISFQSLLKDELDQRRLTILGITLLIGMGVMFLPKEIFSSLPT
ILQYILSNGLIVGTIIVIMLEQLWKTKKASEKNHV

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081750, Length=422, Percent_Identity=28.436018957346, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI87082181, Length=413, Percent_Identity=25.181598062954, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790087, Length=424, Percent_Identity=24.2924528301887, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 46972; Mature: 46972

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKQRFSGALSIFQWFFFLLATSVALPIVIGGVFHLSIKEISDLMQRTFFVVGISSFIQG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CFGHRYPIADGPAGSWVSVFVILAGMAMQQGESTTETLRLLEGGLLVTGFLLIILGITGL
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
FNRLMFLFTPLVTGSFLLILSLQLSGVFLEGMFGIQGQSSLDYQVAAISFGVFVLVIVLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
IKGKGWVRSYSVLLGILFGWLLYFLLGKNSTMISTPASFIKLPDIFAWGTPQLNAGMVIT
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHCCCCHHCCCCCCCCCHHHHH
SIIFTFILVSNTVAAVTAVKQVVPESDASEKQTMNRASWAGGITHVISALFSTIGIVPLP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
VSAGLIKLTGQKRIMPFLIASLALAGIALVPSIVNFLAMLPGPVACAASLASFVQMIGIS
CCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
FQSLLKDELDQRRLTILGITLLIGMGVMFLPKEIFSSLPTILQYILSNGLIVGTIIVIML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
EQLWKTKKASEKNHV
HHHHHHHHCCCCCCC
>Mature Secondary Structure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HHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]