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The map label for this gene is fadB [H]

Identifier: 52140524

GI number: 52140524

Start: 4823919

End: 4826300

Strand: Reverse

Name: fadB [H]

Synonym: BCZK4734

Alternate gene names: 52140524

Gene position: 4826300-4823919 (Counterclockwise)

Preceding gene: 52140523

Following gene: 52140525

Centisome position: 91.05

GC content: 39.34

Gene sequence:

>2382_bases
ATGTTCCAAATTAAAAAGGCTGCTGTTCTAGGGTCAGGCGTAATGGGTTCAGGAATTGCGGCACACTTAGCTAATATTGG
TATTCCGACATTATTGCTTGATATTGTACCACCTGCGCTTACGAAAGAAGAAGAGGCGAAGGGACTTACATTAGAACATA
AAAGTGTGAGAAATCGTTTTAGTAATACGGCTGTGCAAAAACTATTAAAGCAAAAACCAGCTCCTCTGACAGTGAAAGGA
AATTTAGCACTGATTGAAGCAGGTAACTTAGAAGATGATCTTGAGCGTCTAGCTGATGTAGATTGGATTATTGAAGTAGT
AGTTGAAAACTTAGATATTAAAAAGAAACTATTTGAAAAAGTAGATGCTGTTCGTAAACCGGGTTCTATCGTAAGCTCGA
ATACGTCAGGCATTTCAGTTGAAAAAATGGCAGAAGGTCGTTCAGACGACTTCCAGAAACACTTCTTAGGCACACACTTT
TTTAACCCACCACGATATTTAAAACTTCTAGAGGTAATACCGACGAAAGAAACTGATCCACAAGTATTAAGCTTCATGAA
ACTATTTGGCGAAGACGTTCTTGGAAAAGGCGTTGTTATCGCGAAAGACACACCAAACTTTATTGGAAACCGCATCGGTA
CGTACGGTTTATTAGTAACTCTTCAAGAGATGGTAAAACGCGGCTATAGCATTGGGGAAGTTGATTCTGTAACAGGCCCA
CTTATTGGTCGTCCGAAGAGCGCAACGTTCCGTACATTAGATGTTGTCGGTTTAGATACATTTGTACACGTTGCAAATAA
CGTATATGAAAACGTACAAGAAGAAGAGCGTGATGTATTTAAAGTACCAGCTTTCATGCATGACATGCTTGATAAAAAAT
GGCTTGGAAGCAAAACAGGTCAAGGCTTCTTCTTAAAACAAGGAAAAGAAATTTTAGAATTAAATCCAGAAACGATGGAG
TACGAAGCTCGTAAAAAATTAAAAGCTGCATCGATCGAGTTAAGCAAACAAGAAAAAGGTTTATCGAATAAATTGAAAGC
GCTTGTATATGCGAAAGACCGCGCAGGAGAGTTGTTATGGAACATCATCACACCAACTCTTTTATACTCTGCAAAACTTC
ATAAAGAAATTGCTGACGATATCGTTGCAATAGACCAAGCGATGAAGTGGGGCTTCGGCTGGGAGCAAGGACCGTTTGAG
GTTTGGGATGCAATCGGCGTTGAAAAGTCCGTTCAAAAGATGGAAGAAAACGGCGCAGTTATTCCGGCTTGGGTGAAAGA
AATGTTAGAGAAAGGTTTCACTACTTTCTACAAACATGATAACGGAGATAGCTACTATTACGATAATGGCGAATATAAGC
TAATTGAGCGTAATAAAAAGGCAATTTCTCTTAAGCAATTAAAAGCGAAAAATGGCGTATTAAAGAAAAATAGCGGAGCG
AGCTTAATCGATTTAGGCGACGGCATCCTTTGTTTAGAATTCCATTCGAAGAGCAATGCAATTGGTATGGATATTACGCA
AATGATTAACTACGCTGTTGATGAAGTAGAAAAGAATTATAAAGGTCTTGTTATCGGTAACCAATCGAAGAACTTCTGCG
TTGGTGCGAATCTAGCAATGATCTTAATGGAAGCACAAGACGACAACTACTTTGAAATTGAGTGGGTTGTGAAAAACTTC
CAAGATGCAATGATGAAAATTAAATACTCTTCTAAGCCAGTTGTAGCAGCGCCATATGGTATGACGCTTGGCGGAGGTAC
AGAAGTTTGCTTACCAGCAGCGAGCATTCAAGCTTCTAGTGAAACGTATATGGGCTTAGTAGAAGTTGGTGTTGGCTTAA
TCCCTGGCGGAGGCGGTAATAAAGAGCTATACATTAAACACTTAAATAAAATGGCAAACGGCGTAGAATTTGATCTACAA
AAAGTTGCAAATAAAGTGTTCGAAACAGTCGCAATGGCGAAAGTTTCAACTTCAGGACAAGAAGCGGTTTCTCATAACTT
CTTAGGTGATAAAGACGGTATTAGTGTGAATGGTGATCACCTACTATACGATGCAAAACAGAAAGCACTTGCTTTATATG
AAGCTGGTTACAAAGCACCGATTCGTAAAAAGATACCGGTTGTTGGTGAAACAGGATATGCAACTCTTGCACTTGGTGCA
GAAGCAATGCATTTATCTGGTTATATTTCAGAGTACGACCTTCATATTGCGAAGAAACTTGCATATGTCATCGCAGGCGG
AAAAGTGCCGTACGGAACAGAAGTTGATGAGCAGTATTTATTAGATGTAGAACGTGAAGCATTTATTAGCTTAGTCAGTG
AGATGAAATCACAGGCAAGAATGCAGCACATGCTTGTAAAAGGAAAGCCATTACGTAACTAA

Upstream 100 bases:

>100_bases
TAAACAGTATCATATATTTATTAGTAGAGGCTCACTCATTGATTGCGACTTATGTCGAAAAATTGAATGAGCATTCATTC
AAGAATAGGGGGAGAATTGG

Downstream 100 bases:

>100_bases
TAACGAGGGGAGATATCGTTCATGAGAGAAGCTGTCATTGTTGCGGGAGCAAGAACACCAATTGGAAAAGCAAAGAGGGG
TTCATTAAAAACAGTTCGTC

Product: 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase/carnithine racemase fusion

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 793; Mature: 793

Protein sequence:

>793_residues
MFQIKKAAVLGSGVMGSGIAAHLANIGIPTLLLDIVPPALTKEEEAKGLTLEHKSVRNRFSNTAVQKLLKQKPAPLTVKG
NLALIEAGNLEDDLERLADVDWIIEVVVENLDIKKKLFEKVDAVRKPGSIVSSNTSGISVEKMAEGRSDDFQKHFLGTHF
FNPPRYLKLLEVIPTKETDPQVLSFMKLFGEDVLGKGVVIAKDTPNFIGNRIGTYGLLVTLQEMVKRGYSIGEVDSVTGP
LIGRPKSATFRTLDVVGLDTFVHVANNVYENVQEEERDVFKVPAFMHDMLDKKWLGSKTGQGFFLKQGKEILELNPETME
YEARKKLKAASIELSKQEKGLSNKLKALVYAKDRAGELLWNIITPTLLYSAKLHKEIADDIVAIDQAMKWGFGWEQGPFE
VWDAIGVEKSVQKMEENGAVIPAWVKEMLEKGFTTFYKHDNGDSYYYDNGEYKLIERNKKAISLKQLKAKNGVLKKNSGA
SLIDLGDGILCLEFHSKSNAIGMDITQMINYAVDEVEKNYKGLVIGNQSKNFCVGANLAMILMEAQDDNYFEIEWVVKNF
QDAMMKIKYSSKPVVAAPYGMTLGGGTEVCLPAASIQASSETYMGLVEVGVGLIPGGGGNKELYIKHLNKMANGVEFDLQ
KVANKVFETVAMAKVSTSGQEAVSHNFLGDKDGISVNGDHLLYDAKQKALALYEAGYKAPIRKKIPVVGETGYATLALGA
EAMHLSGYISEYDLHIAKKLAYVIAGGKVPYGTEVDEQYLLDVEREAFISLVSEMKSQARMQHMLVKGKPLRN

Sequences:

>Translated_793_residues
MFQIKKAAVLGSGVMGSGIAAHLANIGIPTLLLDIVPPALTKEEEAKGLTLEHKSVRNRFSNTAVQKLLKQKPAPLTVKG
NLALIEAGNLEDDLERLADVDWIIEVVVENLDIKKKLFEKVDAVRKPGSIVSSNTSGISVEKMAEGRSDDFQKHFLGTHF
FNPPRYLKLLEVIPTKETDPQVLSFMKLFGEDVLGKGVVIAKDTPNFIGNRIGTYGLLVTLQEMVKRGYSIGEVDSVTGP
LIGRPKSATFRTLDVVGLDTFVHVANNVYENVQEEERDVFKVPAFMHDMLDKKWLGSKTGQGFFLKQGKEILELNPETME
YEARKKLKAASIELSKQEKGLSNKLKALVYAKDRAGELLWNIITPTLLYSAKLHKEIADDIVAIDQAMKWGFGWEQGPFE
VWDAIGVEKSVQKMEENGAVIPAWVKEMLEKGFTTFYKHDNGDSYYYDNGEYKLIERNKKAISLKQLKAKNGVLKKNSGA
SLIDLGDGILCLEFHSKSNAIGMDITQMINYAVDEVEKNYKGLVIGNQSKNFCVGANLAMILMEAQDDNYFEIEWVVKNF
QDAMMKIKYSSKPVVAAPYGMTLGGGTEVCLPAASIQASSETYMGLVEVGVGLIPGGGGNKELYIKHLNKMANGVEFDLQ
KVANKVFETVAMAKVSTSGQEAVSHNFLGDKDGISVNGDHLLYDAKQKALALYEAGYKAPIRKKIPVVGETGYATLALGA
EAMHLSGYISEYDLHIAKKLAYVIAGGKVPYGTEVDEQYLLDVEREAFISLVSEMKSQARMQHMLVKGKPLRN
>Mature_793_residues
MFQIKKAAVLGSGVMGSGIAAHLANIGIPTLLLDIVPPALTKEEEAKGLTLEHKSVRNRFSNTAVQKLLKQKPAPLTVKG
NLALIEAGNLEDDLERLADVDWIIEVVVENLDIKKKLFEKVDAVRKPGSIVSSNTSGISVEKMAEGRSDDFQKHFLGTHF
FNPPRYLKLLEVIPTKETDPQVLSFMKLFGEDVLGKGVVIAKDTPNFIGNRIGTYGLLVTLQEMVKRGYSIGEVDSVTGP
LIGRPKSATFRTLDVVGLDTFVHVANNVYENVQEEERDVFKVPAFMHDMLDKKWLGSKTGQGFFLKQGKEILELNPETME
YEARKKLKAASIELSKQEKGLSNKLKALVYAKDRAGELLWNIITPTLLYSAKLHKEIADDIVAIDQAMKWGFGWEQGPFE
VWDAIGVEKSVQKMEENGAVIPAWVKEMLEKGFTTFYKHDNGDSYYYDNGEYKLIERNKKAISLKQLKAKNGVLKKNSGA
SLIDLGDGILCLEFHSKSNAIGMDITQMINYAVDEVEKNYKGLVIGNQSKNFCVGANLAMILMEAQDDNYFEIEWVVKNF
QDAMMKIKYSSKPVVAAPYGMTLGGGTEVCLPAASIQASSETYMGLVEVGVGLIPGGGGNKELYIKHLNKMANGVEFDLQ
KVANKVFETVAMAKVSTSGQEAVSHNFLGDKDGISVNGDHLLYDAKQKALALYEAGYKAPIRKKIPVVGETGYATLALGA
EAMHLSGYISEYDLHIAKKLAYVIAGGKVPYGTEVDEQYLLDVEREAFISLVSEMKSQARMQHMLVKGKPLRN

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1250

COG function: function code I; 3-hydroxyacyl-CoA dehydrogenase

Gene ontology:

Cell location: Mitochondria or Peroxisomes [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI296179429, Length=301, Percent_Identity=29.2358803986711, Blast_Score=109, Evalue=1e-23,
Organism=Homo sapiens, GI296179427, Length=322, Percent_Identity=28.2608695652174, Blast_Score=103, Evalue=9e-22,
Organism=Homo sapiens, GI20127408, Length=419, Percent_Identity=26.0143198090692, Blast_Score=95, Evalue=3e-19,
Organism=Homo sapiens, GI261878539, Length=264, Percent_Identity=28.030303030303, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI68989263, Length=264, Percent_Identity=28.030303030303, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI115430219, Length=229, Percent_Identity=27.9475982532751, Blast_Score=71, Evalue=5e-12,
Organism=Escherichia coli, GI1787661, Length=304, Percent_Identity=27.3026315789474, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1790281, Length=318, Percent_Identity=24.5283018867925, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1788682, Length=283, Percent_Identity=27.9151943462898, Blast_Score=70, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17553560, Length=308, Percent_Identity=32.1428571428571, Blast_Score=127, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17549919, Length=303, Percent_Identity=30.3630363036304, Blast_Score=123, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI71985923, Length=414, Percent_Identity=26.0869565217391, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17508951, Length=418, Percent_Identity=26.3157894736842, Blast_Score=97, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17508953, Length=418, Percent_Identity=26.3157894736842, Blast_Score=97, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17563036, Length=301, Percent_Identity=28.9036544850498, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI25144276, Length=303, Percent_Identity=27.7227722772277, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17558304, Length=425, Percent_Identity=25.4117647058824, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71985930, Length=327, Percent_Identity=23.8532110091743, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45549573, Length=275, Percent_Identity=28, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24583077, Length=416, Percent_Identity=25.7211538461538, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24583079, Length=416, Percent_Identity=25.7211538461538, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI19921000, Length=416, Percent_Identity=25.7211538461538, Blast_Score=86, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006176
- InterPro:   IPR006108
- InterPro:   IPR008927
- InterPro:   IPR001753
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00725 3HCDH; PF02737 3HCDH_N; PF00378 ECH [H]

EC number: =1.1.1.35 [H]

Molecular weight: Translated: 87488; Mature: 87488

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQIKKAAVLGSGVMGSGIAAHLANIGIPTLLLDIVPPALTKEEEAKGLTLEHKSVRNRF
CCCCCHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHCCCCCCCCHHCCCCEEEHHHHHHHH
SNTAVQKLLKQKPAPLTVKGNLALIEAGNLEDDLERLADVDWIIEVVVENLDIKKKLFEK
HHHHHHHHHHCCCCCEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VDAVRKPGSIVSSNTSGISVEKMAEGRSDDFQKHFLGTHFFNPPRYLKLLEVIPTKETDP
HHHHCCCCCEEECCCCCCCHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCH
QVLSFMKLFGEDVLGKGVVIAKDTPNFIGNRIGTYGLLVTLQEMVKRGYSIGEVDSVTGP
HHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
LIGRPKSATFRTLDVVGLDTFVHVANNVYENVQEEERDVFKVPAFMHDMLDKKWLGSKTG
CCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
QGFFLKQGKEILELNPETMEYEARKKLKAASIELSKQEKGLSNKLKALVYAKDRAGELLW
CCEEHHCCCHHHHCCCHHHHHHHHHHHHHHHEEHHHHHCCHHHHHEEEEEECCCHHHHHH
NIITPTLLYSAKLHKEIADDIVAIDQAMKWGFGWEQGPFEVWDAIGVEKSVQKMEENGAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCHHHHHHHHHHCCCE
IPAWVKEMLEKGFTTFYKHDNGDSYYYDNGEYKLIERNKKAISLKQLKAKNGVLKKNSGA
EHHHHHHHHHCCCCEEEEECCCCCEEEECCCEEEEECCCCHHHHHHHHHHCCCEECCCCC
SLIDLGDGILCLEFHSKSNAIGMDITQMINYAVDEVEKNYKGLVIGNQSKNFCVGANLAM
CEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCEEE
ILMEAQDDNYFEIEWVVKNFQDAMMKIKYSSKPVVAAPYGMTLGGGTEVCLPAASIQASS
EEEECCCCCEEEEHHHHHHHHHHHHEEEECCCCEEECCCCEEECCCCCEEEECHHCCCCC
ETYMGLVEVGVGLIPGGGGNKELYIKHLNKMANGVEFDLQKVANKVFETVAMAKVSTSGQ
HHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCH
EAVSHNFLGDKDGISVNGDHLLYDAKQKALALYEAGYKAPIRKKIPVVGETGYATLALGA
HHHHHCCCCCCCCCEECCCEEEEECHHHHHHHHHCCCCCCCHHCCCEECCCCCEEEEECC
EAMHLSGYISEYDLHIAKKLAYVIAGGKVPYGTEVDEQYLLDVEREAFISLVSEMKSQAR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MQHMLVKGKPLRN
HHHHHHCCCCCCC
>Mature Secondary Structure
MFQIKKAAVLGSGVMGSGIAAHLANIGIPTLLLDIVPPALTKEEEAKGLTLEHKSVRNRF
CCCCCHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHCCCCCCCCHHCCCCEEEHHHHHHHH
SNTAVQKLLKQKPAPLTVKGNLALIEAGNLEDDLERLADVDWIIEVVVENLDIKKKLFEK
HHHHHHHHHHCCCCCEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VDAVRKPGSIVSSNTSGISVEKMAEGRSDDFQKHFLGTHFFNPPRYLKLLEVIPTKETDP
HHHHCCCCCEEECCCCCCCHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCH
QVLSFMKLFGEDVLGKGVVIAKDTPNFIGNRIGTYGLLVTLQEMVKRGYSIGEVDSVTGP
HHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
LIGRPKSATFRTLDVVGLDTFVHVANNVYENVQEEERDVFKVPAFMHDMLDKKWLGSKTG
CCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
QGFFLKQGKEILELNPETMEYEARKKLKAASIELSKQEKGLSNKLKALVYAKDRAGELLW
CCEEHHCCCHHHHCCCHHHHHHHHHHHHHHHEEHHHHHCCHHHHHEEEEEECCCHHHHHH
NIITPTLLYSAKLHKEIADDIVAIDQAMKWGFGWEQGPFEVWDAIGVEKSVQKMEENGAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCHHHHHHHHHHCCCE
IPAWVKEMLEKGFTTFYKHDNGDSYYYDNGEYKLIERNKKAISLKQLKAKNGVLKKNSGA
EHHHHHHHHHCCCCEEEEECCCCCEEEECCCEEEEECCCCHHHHHHHHHHCCCEECCCCC
SLIDLGDGILCLEFHSKSNAIGMDITQMINYAVDEVEKNYKGLVIGNQSKNFCVGANLAM
CEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCEEE
ILMEAQDDNYFEIEWVVKNFQDAMMKIKYSSKPVVAAPYGMTLGGGTEVCLPAASIQASS
EEEECCCCCEEEEHHHHHHHHHHHHEEEECCCCEEECCCCEEECCCCCEEEECHHCCCCC
ETYMGLVEVGVGLIPGGGGNKELYIKHLNKMANGVEFDLQKVANKVFETVAMAKVSTSGQ
HHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCH
EAVSHNFLGDKDGISVNGDHLLYDAKQKALALYEAGYKAPIRKKIPVVGETGYATLALGA
HHHHHCCCCCCCCCEECCCEEEEECHHHHHHHHHCCCCCCCHHCCCEECCCCCEEEEECC
EAMHLSGYISEYDLHIAKKLAYVIAGGKVPYGTEVDEQYLLDVEREAFISLVSEMKSQAR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MQHMLVKGKPLRN
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]