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The map label for this gene is ydgM [C]

Identifier: 51894427

GI number: 51894427

Start: 3516955

End: 3518325

Strand: Reverse

Name: ydgM [C]

Synonym: STH3293

Alternate gene names: 51894427

Gene position: 3518325-3516955 (Counterclockwise)

Preceding gene: 51894428

Following gene: 51894426

Centisome position: 98.66

GC content: 67.03

Gene sequence:

>1371_bases
GTGATTTTCATCGATCAGGAACTCTGCACCGGTTGCCGTCGCTGTGCCGAAGTCTGCCCGGTGGACGCCATCGTCGGCGA
GCCGGGGAAGCCGCAGTCGGTTGACCAGGAGATCTGCGTGATGTGCGGCCAGTGCGTCCAGGTCTGCAGCTCCTACGGCT
CGATCTGGGACGACGGCCTCACCCCCCGCGAACAGAAGCTGGCCGAGCGTGGGCTGCTGCCCTCCGTGAAGGAGCCGCTG
TTCGCCGCCTGGAACGAGGGCCGGGCGAAGCTGGTAAAGGAGGCCCTGGCGGACCCGGACAGGTACGTCATGGTGCAGGT
GGCCCCGGCGGTCCGCGTGGCCATCGCCGAGGAGTTCGGCATGCCGCTGGGCAGCCTGGCGCCGGGCAAGATGGCCGCGG
CGCTGCGCCGGCTGGGCTTCGACCGGGTCTACTCCACCGACTTCACTGCCGACCTGACCATCATGGAGGAGGGCAACGAG
CTGATCGAGCGGGTGACCAAGGGCGGCACCCTGCCGATGTTCACCAGCTGCTGCCCGGCCTGGGTGAAGTACCTGGAGCA
GACCTATCCCGAGCTGCTGCCGCACCTGTCCACCTGCAAGTCGCCGCAGCAGATGGCCGGCGCCCTGTTCAAGACCTATG
GGGCCAAGGTGGACAATGTCGACCCGGCGAAGGTCTACAGCGTCTCCGTCATGCCCTGTACCTGCAAGGACTTCGAGTCC
GGCCGGCCGGAGATGAAGGCCAGCGGCTACCGGGACGTGGACGTGGTCATCACCACCCGGGAGCTGGCGCACCTGATCAA
GGACGCCGGCATCGACTTCAACGCGCTGCCGGAGGAGGAGTACGACCGGCCGCTGGGGCTCTACACGGGTGCCGGCACCA
TCTTCGGCGCGACCGGCGGAGTGATGGAAGCGGCCCTCCGGACGGCGTATGAGGTGATCGCCAAGAAGCCAATCCCCGAG
CTGGACCTGAAGTTCGTGCGCGGCGGCGAGGGCGTGCGGTACGCCACCGTGAAGATCGAGGACCTGGAGCTGAAGGTCTG
CGTGGTCTCCGGCCTGAAGAACGTCGCCCCGGTGCTGGAGCAGGTGAAGGCGGGGAAGGCCGACTTCCACTTCATGGAGG
TCATGACCTGCCCGGTGGGCTGCGTCTCCGGCGGCGGCCAGCCCAAGGCGCTCCTGCCCTCGGACCGGCTGTGCGCCCGC
ATGGCCCGCACGGAGTCCACGTACCGGCATGACGCCCAGTTGCCCCACAGGAAGTCCAACGAGAACCCGGACATCAAGAA
GATCTACAAGGAGTTCCTGGGCAAGCCGTTGGGCGAGAAATCGCATCACCTGCTGCACACCAGCTACACGCCGAGGAGGC
GCAAGGCATGA

Upstream 100 bases:

>100_bases
AGGTCGTCCGACCCGATGAGCTGCGCCGGACCCGGAACCTGGAGGCCGCCCTGGCCGTGCTCGAGTCCGTGAAGAACGTC
GTCGGGTAGGAGGGACCGCC

Downstream 100 bases:

>100_bases
CGAAGAGCGCGTTCGTGCTGGCCGACCCGACCAAGTGCATCGGGTGCCAGTCCTGCGAGATCGCCTGCGCCGTCGCCCAT
CTGGGCACATCGGTCACCAC

Product: iron hydrogenase

Products: NA

Alternate protein names: CpI; Fe-only hydrogenase; [Fe] hydrogenase [H]

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MIFIDQELCTGCRRCAEVCPVDAIVGEPGKPQSVDQEICVMCGQCVQVCSSYGSIWDDGLTPREQKLAERGLLPSVKEPL
FAAWNEGRAKLVKEALADPDRYVMVQVAPAVRVAIAEEFGMPLGSLAPGKMAAALRRLGFDRVYSTDFTADLTIMEEGNE
LIERVTKGGTLPMFTSCCPAWVKYLEQTYPELLPHLSTCKSPQQMAGALFKTYGAKVDNVDPAKVYSVSVMPCTCKDFES
GRPEMKASGYRDVDVVITTRELAHLIKDAGIDFNALPEEEYDRPLGLYTGAGTIFGATGGVMEAALRTAYEVIAKKPIPE
LDLKFVRGGEGVRYATVKIEDLELKVCVVSGLKNVAPVLEQVKAGKADFHFMEVMTCPVGCVSGGGQPKALLPSDRLCAR
MARTESTYRHDAQLPHRKSNENPDIKKIYKEFLGKPLGEKSHHLLHTSYTPRRRKA

Sequences:

>Translated_456_residues
MIFIDQELCTGCRRCAEVCPVDAIVGEPGKPQSVDQEICVMCGQCVQVCSSYGSIWDDGLTPREQKLAERGLLPSVKEPL
FAAWNEGRAKLVKEALADPDRYVMVQVAPAVRVAIAEEFGMPLGSLAPGKMAAALRRLGFDRVYSTDFTADLTIMEEGNE
LIERVTKGGTLPMFTSCCPAWVKYLEQTYPELLPHLSTCKSPQQMAGALFKTYGAKVDNVDPAKVYSVSVMPCTCKDFES
GRPEMKASGYRDVDVVITTRELAHLIKDAGIDFNALPEEEYDRPLGLYTGAGTIFGATGGVMEAALRTAYEVIAKKPIPE
LDLKFVRGGEGVRYATVKIEDLELKVCVVSGLKNVAPVLEQVKAGKADFHFMEVMTCPVGCVSGGGQPKALLPSDRLCAR
MARTESTYRHDAQLPHRKSNENPDIKKIYKEFLGKPLGEKSHHLLHTSYTPRRRKA
>Mature_456_residues
MIFIDQELCTGCRRCAEVCPVDAIVGEPGKPQSVDQEICVMCGQCVQVCSSYGSIWDDGLTPREQKLAERGLLPSVKEPL
FAAWNEGRAKLVKEALADPDRYVMVQVAPAVRVAIAEEFGMPLGSLAPGKMAAALRRLGFDRVYSTDFTADLTIMEEGNE
LIERVTKGGTLPMFTSCCPAWVKYLEQTYPELLPHLSTCKSPQQMAGALFKTYGAKVDNVDPAKVYSVSVMPCTCKDFES
GRPEMKASGYRDVDVVITTRELAHLIKDAGIDFNALPEEEYDRPLGLYTGAGTIFGATGGVMEAALRTAYEVIAKKPIPE
LDLKFVRGGEGVRYATVKIEDLELKVCVVSGLKNVAPVLEQVKAGKADFHFMEVMTCPVGCVSGGGQPKALLPSDRLCAR
MARTESTYRHDAQLPHRKSNENPDIKKIYKEFLGKPLGEKSHHLLHTSYTPRRRKA

Specific function: Unknown

COG id: COG4624

COG function: function code R; Iron only hydrogenase large subunit, C-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI11968051, Length=425, Percent_Identity=30.1176470588235, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI6912524, Length=384, Percent_Identity=28.3854166666667, Blast_Score=155, Evalue=7e-38,
Organism=Homo sapiens, GI84452151, Length=384, Percent_Identity=28.3854166666667, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI134284357, Length=373, Percent_Identity=28.686327077748, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI14165461, Length=430, Percent_Identity=25.3488372093023, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71995015, Length=407, Percent_Identity=29.7297297297297, Blast_Score=125, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6324089, Length=337, Percent_Identity=24.0356083086053, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI116007464, Length=404, Percent_Identity=29.9504950495049, Blast_Score=158, Evalue=9e-39,
Organism=Drosophila melanogaster, GI116007468, Length=404, Percent_Identity=29.9504950495049, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI116007470, Length=404, Percent_Identity=29.9504950495049, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI116007466, Length=404, Percent_Identity=29.9504950495049, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI116007462, Length=288, Percent_Identity=32.2916666666667, Blast_Score=135, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR009016
- InterPro:   IPR004108
- InterPro:   IPR003149
- InterPro:   IPR013352
- InterPro:   IPR001041 [H]

Pfam domain/function: PF02906 Fe_hyd_lg_C; PF02256 Fe_hyd_SSU [H]

EC number: =1.12.7.2 [H]

Molecular weight: Translated: 50062; Mature: 50062

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFIDQELCTGCRRCAEVCPVDAIVGEPGKPQSVDQEICVMCGQCVQVCSSYGSIWDDGL
CEEECHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHCCCC
TPREQKLAERGLLPSVKEPLFAAWNEGRAKLVKEALADPDRYVMVQVAPAVRVAIAEEFG
CCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHC
MPLGSLAPGKMAAALRRLGFDRVYSTDFTADLTIMEEGNELIERVTKGGTLPMFTSCCPA
CCCCCCCCHHHHHHHHHHCCHHHCCCCCCEEEEEECCCHHHHHHHHCCCCCCHHHHHHHH
WVKYLEQTYPELLPHLSTCKSPQQMAGALFKTYGAKVDNVDPAKVYSVSVMPCTCKDFES
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCHHCC
GRPEMKASGYRDVDVVITTRELAHLIKDAGIDFNALPEEEYDRPLGLYTGAGTIFGATGG
CCCCCCCCCCCCEEEEEEHHHHHHHHHHCCCCCCCCCHHHCCCCCEEEECCCCEECCCHH
VMEAALRTAYEVIAKKPIPELDLKFVRGGEGVRYATVKIEDLELKVCVVSGLKNVAPVLE
HHHHHHHHHHHHHHHCCCCCCCHHEEECCCCEEEEEEEEECCEEEHHHHHHHHHHHHHHH
QVKAGKADFHFMEVMTCPVGCVSGGGQPKALLPSDRLCARMARTESTYRHDAQLPHRKSN
HHHCCCCHHHHHHHHHCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
ENPDIKKIYKEFLGKPLGEKSHHLLHTSYTPRRRKA
CCCCHHHHHHHHHCCCCCCCCCEEEECCCCCHHCCC
>Mature Secondary Structure
MIFIDQELCTGCRRCAEVCPVDAIVGEPGKPQSVDQEICVMCGQCVQVCSSYGSIWDDGL
CEEECHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHCCCC
TPREQKLAERGLLPSVKEPLFAAWNEGRAKLVKEALADPDRYVMVQVAPAVRVAIAEEFG
CCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHC
MPLGSLAPGKMAAALRRLGFDRVYSTDFTADLTIMEEGNELIERVTKGGTLPMFTSCCPA
CCCCCCCCHHHHHHHHHHCCHHHCCCCCCEEEEEECCCHHHHHHHHCCCCCCHHHHHHHH
WVKYLEQTYPELLPHLSTCKSPQQMAGALFKTYGAKVDNVDPAKVYSVSVMPCTCKDFES
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCHHCC
GRPEMKASGYRDVDVVITTRELAHLIKDAGIDFNALPEEEYDRPLGLYTGAGTIFGATGG
CCCCCCCCCCCCEEEEEEHHHHHHHHHHCCCCCCCCCHHHCCCCCEEEECCCCEECCCHH
VMEAALRTAYEVIAKKPIPELDLKFVRGGEGVRYATVKIEDLELKVCVVSGLKNVAPVLE
HHHHHHHHHHHHHHHCCCCCCCHHEEECCCCEEEEEEEEECCEEEHHHHHHHHHHHHHHH
QVKAGKADFHFMEVMTCPVGCVSGGGQPKALLPSDRLCARMARTESTYRHDAQLPHRKSN
HHHCCCCHHHHHHHHHCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
ENPDIKKIYKEFLGKPLGEKSHHLLHTSYTPRRRKA
CCCCHHHHHHHHHCCCCCCCCCEEEECCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1911757; 9836629; 10529166 [H]