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The map label for this gene is speA [H]

Identifier: 51894394

GI number: 51894394

Start: 3477988

End: 3479397

Strand: Reverse

Name: speA [H]

Synonym: STH3259

Alternate gene names: 51894394

Gene position: 3479397-3477988 (Counterclockwise)

Preceding gene: 51894395

Following gene: 51894393

Centisome position: 97.57

GC content: 74.26

Gene sequence:

>1410_bases
ATGGCGGAGGAGCAGGCCCGGACGCCGCTGTTTTCGGCGCTGAGGGAGTACGTTGCGCGGGTCCGGGCGCCGCTGCACGT
GCCCGGGCACAAGATGGGACGCGCCGCGCCCTCGGCGTGGCGGGAGTTCCTGGGGCCGAATGCACTGGCGATCGACCTGA
CGGAGGCGCCGGGGCTGGACGACCTGCACGCGCCGGAGGGGGTCATCGCCGAGGCCCAGGAGCTGGCGGCCCGGGCGTTC
GGCGCGTGGCGGAGTTATTTTCTGGTGGGCGGTACCACCGCCGGCCTGCACGCCCTCATCCTCGCCGCCTGCCATCCGGG
AGAGGCGATCGCGGTGCCGCGCAACGCGCACCGCTCCGTGCTGGGCGCCCTGATTCTGGCCGGGGTCCGTCCTCACTGGG
TGAGGGTGGCCTTCGACCCGGACCTGGGCATCGCCACGGGCCCGGTCCTCACGTCGCTGGAGGAGGCGCTTTCCGGCGCC
GCGGCCGCGGTGCTGGTCCATCCCACGTATTACGGCATCGCCGGAGACACGGCCGCCGCGATCGACCTGATCCACCGCGC
GGCCGTCCCGGCCCTGGTGGACGAGGCGCACGGCGCCCACTTCCCGTTCCACCCCGCGCTGCCGCCCTCGGCCCTGGAAC
TGGGCGCGGACGGCGTCGTGCAGTCGCTGCACAAGACCGGGGGCAGCCTGACCCAGTCGTCCCTGTGCCACCTGGGGCAC
GGCAGCCGCATCGCCCCCGAACGGCTGCAGGAGATGCTGCGGCTCGTGCAGTCCACAAGCCCGTCGTACCTGCTCATGGC
TTCCCTGGACCTGGCCCGGCGCGAGCTGGCCCTCGGGGGCCGGGAGGCCTGGGGGCGGGCCCTGGAGCTGGCCCACGAGG
CGAAACGGCGCATCGACGCCCTGCCCGGGCTCCGGGTGCGCCCCACCGACGACCCGACCAAGCTGCTCATCGACGTGCGG
GGACGGTCCATTTCGGGCTTCCGGGCGGCGGAGCGGCTCTGGGAGGAGGCCGGCGTCGCCGTCGAGGCCTCCGGGCTGAC
CTACGTGCTCGCCGTGCTCTCGCCCGGGGACTCCCGGGAGCAGATCGACGCCCTGGTCGCGGGGCTGGAGCGGCTGTCCT
CCGAGGGGGATGTCCCGGCCCTTCCGCCGGAGCCGCCCTGGCCCGAGGTGGTTCTGCCGCCGCGGGAGGCATACTTAGCC
CGTAAGAAGGCGGTTCCGCTTCGCCAGGCCCGGGGGCGCATCGCGGCGGAGCTGGTGGCCCCGTACCCGCCGGGCATTCC
GGTGGTGGCCCCGGGTGAGCGGCTGACGGCTGACGTGCTGGACTACCTCCGGCGCGCCGCCGATGCCGGCTGGCACCTTC
AGGGCCCGGCAGACCCCGCGCTGCGAAGCATCCAGGTCGTGGAGGAGTGA

Upstream 100 bases:

>100_bases
GAGAGGACGTGCGGCGGGTGCTGCGCCTGCGGGCGGGGGAACGGTGAACGGAGGTGTACTGCGGCGCACCGTCGAATACA
GCCGTGAGGAGGGTGGCCCG

Downstream 100 bases:

>100_bases
ACCGCGGTGTCGGTGTTCATCAGCTTCGAGGGGGTCGACGGCTCCGGCAAGTCGACCCAGATCCGGCTCCTGTTGCAGTA
CCTCGACGAGCAGAGCGTGC

Product: arginine/lysine/ornithine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 468

Protein sequence:

>469_residues
MAEEQARTPLFSALREYVARVRAPLHVPGHKMGRAAPSAWREFLGPNALAIDLTEAPGLDDLHAPEGVIAEAQELAARAF
GAWRSYFLVGGTTAGLHALILAACHPGEAIAVPRNAHRSVLGALILAGVRPHWVRVAFDPDLGIATGPVLTSLEEALSGA
AAAVLVHPTYYGIAGDTAAAIDLIHRAAVPALVDEAHGAHFPFHPALPPSALELGADGVVQSLHKTGGSLTQSSLCHLGH
GSRIAPERLQEMLRLVQSTSPSYLLMASLDLARRELALGGREAWGRALELAHEAKRRIDALPGLRVRPTDDPTKLLIDVR
GRSISGFRAAERLWEEAGVAVEASGLTYVLAVLSPGDSREQIDALVAGLERLSSEGDVPALPPEPPWPEVVLPPREAYLA
RKKAVPLRQARGRIAAELVAPYPPGIPVVAPGERLTADVLDYLRRAADAGWHLQGPADPALRSIQVVEE

Sequences:

>Translated_469_residues
MAEEQARTPLFSALREYVARVRAPLHVPGHKMGRAAPSAWREFLGPNALAIDLTEAPGLDDLHAPEGVIAEAQELAARAF
GAWRSYFLVGGTTAGLHALILAACHPGEAIAVPRNAHRSVLGALILAGVRPHWVRVAFDPDLGIATGPVLTSLEEALSGA
AAAVLVHPTYYGIAGDTAAAIDLIHRAAVPALVDEAHGAHFPFHPALPPSALELGADGVVQSLHKTGGSLTQSSLCHLGH
GSRIAPERLQEMLRLVQSTSPSYLLMASLDLARRELALGGREAWGRALELAHEAKRRIDALPGLRVRPTDDPTKLLIDVR
GRSISGFRAAERLWEEAGVAVEASGLTYVLAVLSPGDSREQIDALVAGLERLSSEGDVPALPPEPPWPEVVLPPREAYLA
RKKAVPLRQARGRIAAELVAPYPPGIPVVAPGERLTADVLDYLRRAADAGWHLQGPADPALRSIQVVEE
>Mature_468_residues
AEEQARTPLFSALREYVARVRAPLHVPGHKMGRAAPSAWREFLGPNALAIDLTEAPGLDDLHAPEGVIAEAQELAARAFG
AWRSYFLVGGTTAGLHALILAACHPGEAIAVPRNAHRSVLGALILAGVRPHWVRVAFDPDLGIATGPVLTSLEEALSGAA
AAVLVHPTYYGIAGDTAAAIDLIHRAAVPALVDEAHGAHFPFHPALPPSALELGADGVVQSLHKTGGSLTQSSLCHLGHG
SRIAPERLQEMLRLVQSTSPSYLLMASLDLARRELALGGREAWGRALELAHEAKRRIDALPGLRVRPTDDPTKLLIDVRG
RSISGFRAAERLWEEAGVAVEASGLTYVLAVLSPGDSREQIDALVAGLERLSSEGDVPALPPEPPWPEVVLPPREAYLAR
KKAVPLRQARGRIAAELVAPYPPGIPVVAPGERLTADVLDYLRRAADAGWHLQGPADPALRSIQVVEE

Specific function: Catalyzes the formation of agmatine from arginine [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI87082193, Length=569, Percent_Identity=26.3620386643234, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1786384, Length=568, Percent_Identity=25.5281690140845, Blast_Score=122, Evalue=7e-29,
Organism=Escherichia coli, GI1786909, Length=604, Percent_Identity=25.6622516556291, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1790573, Length=571, Percent_Identity=23.292469352014, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI221142684, Length=301, Percent_Identity=26.9102990033223, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 49805; Mature: 49673

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEEQARTPLFSALREYVARVRAPLHVPGHKMGRAAPSAWREFLGPNALAIDLTEAPGLD
CCCHHHCCHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHCCCEEEEEECCCCCCC
DLHAPEGVIAEAQELAARAFGAWRSYFLVGGTTAGLHALILAACHPGEAIAVPRNAHRSV
CCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHCCCCCEEECCCHHHHHH
LGALILAGVRPHWVRVAFDPDLGIATGPVLTSLEEALSGAAAAVLVHPTYYGIAGDTAAA
HHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEECCCEECCCCCHHHH
IDLIHRAAVPALVDEAHGAHFPFHPALPPSALELGADGVVQSLHKTGGSLTQSSLCHLGH
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCHHHHHHHHHHCCCCHHHHHHHHCCC
GSRIAPERLQEMLRLVQSTSPSYLLMASLDLARRELALGGREAWGRALELAHEAKRRIDA
CCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LPGLRVRPTDDPTKLLIDVRGRSISGFRAAERLWEEAGVAVEASGLTYVLAVLSPGDSRE
CCCCEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCEEEEEEECCCCCHH
QIDALVAGLERLSSEGDVPALPPEPPWPEVVLPPREAYLARKKAVPLRQARGRIAAELVA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHCCCHHHHHCHHHHHHCC
PYPPGIPVVAPGERLTADVLDYLRRAADAGWHLQGPADPALRSIQVVEE
CCCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
AEEQARTPLFSALREYVARVRAPLHVPGHKMGRAAPSAWREFLGPNALAIDLTEAPGLD
CCHHHCCHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHCCCEEEEEECCCCCCC
DLHAPEGVIAEAQELAARAFGAWRSYFLVGGTTAGLHALILAACHPGEAIAVPRNAHRSV
CCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHCCCCCEEECCCHHHHHH
LGALILAGVRPHWVRVAFDPDLGIATGPVLTSLEEALSGAAAAVLVHPTYYGIAGDTAAA
HHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEECCCEECCCCCHHHH
IDLIHRAAVPALVDEAHGAHFPFHPALPPSALELGADGVVQSLHKTGGSLTQSSLCHLGH
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCHHHHHHHHHHCCCCHHHHHHHHCCC
GSRIAPERLQEMLRLVQSTSPSYLLMASLDLARRELALGGREAWGRALELAHEAKRRIDA
CCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LPGLRVRPTDDPTKLLIDVRGRSISGFRAAERLWEEAGVAVEASGLTYVLAVLSPGDSRE
CCCCEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCEEEEEEECCCCCHH
QIDALVAGLERLSSEGDVPALPPEPPWPEVVLPPREAYLARKKAVPLRQARGRIAAELVA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHCCCHHHHHCHHHHHHCC
PYPPGIPVVAPGERLTADVLDYLRRAADAGWHLQGPADPALRSIQVVEE
CCCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969500; 9384377; 1697575; 1936936 [H]