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The map label for this gene is yabD [H]

Identifier: 51894386

GI number: 51894386

Start: 3470012

End: 3470788

Strand: Reverse

Name: yabD [H]

Synonym: STH3251

Alternate gene names: 51894386

Gene position: 3470788-3470012 (Counterclockwise)

Preceding gene: 51894387

Following gene: 51894385

Centisome position: 97.33

GC content: 67.31

Gene sequence:

>777_bases
ATGTTGTTCAACACGCATTCGCACGTGGACACGGGGCGCCAGTTCGCTGTAGACCGCGACGAGGTGGTCGCTCGGGCGCG
GGAGATGGGCGTCAGCCAGCTGATGGTGATCGGGTTTGAGCGGGCGCTGATTCCGGTGACGCTGGCCTTTGCCGAGCGGC
ATGACTGGGTGTGGGCGGCGGTGGGCATCCATCCCACCAGTGCGCTGGAATGGGGCCCCGATGCCGAGCGTGAGCTGCGC
GAAGCGGCGAGGAGTCCCAAGGTAAGGGCCATCGGCGAGGTGGGCCTCGACTACTACTGGAAGGACAAGGCGCCCTTCGA
GGTGCAGAGGGATGTCTTCCGGCAGCAGATTCGTCTGGCCCGGGATCTGGGGCTGCCGCTGGTCATTCATAACCGCGACG
CGCACGAGGACGTGGTGCGGATCCTCGAGGAGGAGGGCGCGGACGAGGTCGGCGGCATCATGCACTGCTTTTCCGGCGAC
TGGGAGATGGCAGAGCGGTGTCTTGCGCTGAACTTCTACATCGGGATCGGCGGCACGGTGACGTACAAGAACAACCCGGT
CGGCCGCGAGGTGGCGCAGCGGCTGCCGCTGGATCGCATCGTGCTGGAGACCGACGATCCGTACCTCGCGCCGGTGCCGT
ACCGGGGCAAGCGGAACGAGCCCGGGTACGTGCGCATCGTGGCGGAGTTCGTGGCCGAGCTGCGCGGCCTCACGCTGGAG
GCGATCGCCGAGGCGACGATGGCCAACGCGCGCCGTGCGCTCCGCCTGGATGCGTAA

Upstream 100 bases:

>100_bases
CGGACTTCCCCACCGGGATGCGCGTGAAGTAGGTCAAATCCAGTCTCCCCGGGCGCCTCGCAGCGGCGCCCGGGGAGATG
AACTGAGAGAGGGACGCGGC

Downstream 100 bases:

>100_bases
AGGGTCGGAACATTGCTCTGTGTTGACGGACCGCCCGGCAGTGGCTATACTAACATCTTGCCGGGCGGCGCGGATCCCCA
GCAACTGGGCGATTGACGCG

Product: TatD-related DNase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MLFNTHSHVDTGRQFAVDRDEVVARAREMGVSQLMVIGFERALIPVTLAFAERHDWVWAAVGIHPTSALEWGPDAERELR
EAARSPKVRAIGEVGLDYYWKDKAPFEVQRDVFRQQIRLARDLGLPLVIHNRDAHEDVVRILEEEGADEVGGIMHCFSGD
WEMAERCLALNFYIGIGGTVTYKNNPVGREVAQRLPLDRIVLETDDPYLAPVPYRGKRNEPGYVRIVAEFVAELRGLTLE
AIAEATMANARRALRLDA

Sequences:

>Translated_258_residues
MLFNTHSHVDTGRQFAVDRDEVVARAREMGVSQLMVIGFERALIPVTLAFAERHDWVWAAVGIHPTSALEWGPDAERELR
EAARSPKVRAIGEVGLDYYWKDKAPFEVQRDVFRQQIRLARDLGLPLVIHNRDAHEDVVRILEEEGADEVGGIMHCFSGD
WEMAERCLALNFYIGIGGTVTYKNNPVGREVAQRLPLDRIVLETDDPYLAPVPYRGKRNEPGYVRIVAEFVAELRGLTLE
AIAEATMANARRALRLDA
>Mature_258_residues
MLFNTHSHVDTGRQFAVDRDEVVARAREMGVSQLMVIGFERALIPVTLAFAERHDWVWAAVGIHPTSALEWGPDAERELR
EAARSPKVRAIGEVGLDYYWKDKAPFEVQRDVFRQQIRLARDLGLPLVIHNRDAHEDVVRILEEEGADEVGGIMHCFSGD
WEMAERCLALNFYIGIGGTVTYKNNPVGREVAQRLPLDRIVLETDDPYLAPVPYRGKRNEPGYVRIVAEFVAELRGLTLE
AIAEATMANARRALRLDA

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI225903424, Length=203, Percent_Identity=37.4384236453202, Blast_Score=121, Evalue=7e-28,
Organism=Homo sapiens, GI110349734, Length=265, Percent_Identity=28.6792452830189, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI110349730, Length=265, Percent_Identity=28.6792452830189, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI226061853, Length=270, Percent_Identity=28.1481481481481, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI226061614, Length=255, Percent_Identity=28.2352941176471, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI14042943, Length=246, Percent_Identity=28.4552845528455, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI225903439, Length=216, Percent_Identity=28.2407407407407, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI226061595, Length=230, Percent_Identity=27.3913043478261, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI1787342, Length=264, Percent_Identity=37.5, Blast_Score=175, Evalue=3e-45,
Organism=Escherichia coli, GI48994985, Length=246, Percent_Identity=35.3658536585366, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI87082439, Length=252, Percent_Identity=33.7301587301587, Blast_Score=132, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17559024, Length=271, Percent_Identity=30.2583025830258, Blast_Score=139, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17543026, Length=216, Percent_Identity=34.2592592592593, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17565396, Length=218, Percent_Identity=34.4036697247706, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71980746, Length=268, Percent_Identity=25.7462686567164, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24586117, Length=218, Percent_Identity=35.3211009174312, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI221330018, Length=218, Percent_Identity=35.3211009174312, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24648690, Length=277, Percent_Identity=30.3249097472924, Blast_Score=101, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.- [C]

Molecular weight: Translated: 29130; Mature: 29130

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFNTHSHVDTGRQFAVDRDEVVARAREMGVSQLMVIGFERALIPVTLAFAERHDWVWAA
CCCCCCCCCCCCCHHCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
VGIHPTSALEWGPDAERELREAARSPKVRAIGEVGLDYYWKDKAPFEVQRDVFRQQIRLA
ECCCCCCCCCCCCCHHHHHHHHHHCCCEEEHHHCCCCEEECCCCCHHHHHHHHHHHHHHH
RDLGLPLVIHNRDAHEDVVRILEEEGADEVGGIMHCFSGDWEMAERCLALNFYIGIGGTV
HHCCCEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHEEEEEECCCEE
TYKNNPVGREVAQRLPLDRIVLETDDPYLAPVPYRGKRNEPGYVRIVAEFVAELRGLTLE
EECCCCCHHHHHHHCCCCEEEEECCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHCCHHH
AIAEATMANARRALRLDA
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLFNTHSHVDTGRQFAVDRDEVVARAREMGVSQLMVIGFERALIPVTLAFAERHDWVWAA
CCCCCCCCCCCCCHHCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
VGIHPTSALEWGPDAERELREAARSPKVRAIGEVGLDYYWKDKAPFEVQRDVFRQQIRLA
ECCCCCCCCCCCCCHHHHHHHHHHCCCEEEHHHCCCCEEECCCCCHHHHHHHHHHHHHHH
RDLGLPLVIHNRDAHEDVVRILEEEGADEVGGIMHCFSGDWEMAERCLALNFYIGIGGTV
HHCCCEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHEEEEEECCCEE
TYKNNPVGREVAQRLPLDRIVLETDDPYLAPVPYRGKRNEPGYVRIVAEFVAELRGLTLE
EECCCCCHHHHHHHCCCCEEEEECCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHCCHHH
AIAEATMANARRALRLDA
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]