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The map label for this gene is ptxB [H]

Identifier: 51894357

GI number: 51894357

Start: 3436865

End: 3437869

Strand: Reverse

Name: ptxB [H]

Synonym: STH3222

Alternate gene names: 51894357

Gene position: 3437869-3436865 (Counterclockwise)

Preceding gene: 51894358

Following gene: 51894356

Centisome position: 96.4

GC content: 66.97

Gene sequence:

>1005_bases
ATGCCGCATTCGCGGCAGGTACGAAAGAATCCAGACGAGAAGTATCAGCCGTTGGCTCGAAGTAGGTGGAGGTGGATGCG
CGTGCGGCGCCCCCTGTCTGTCCTGTTGCTGGCAGCGGTGGTGAGCCTGTGGGGCTGCGCTTCGGCTCCCCAGTTGCCCG
AGGTGCGACTGAACCAACTCGACCGCACCCTGGCGGCCGGGTCAGTCGGCATCTCGCCGCGACCGGTCCTGAAGGTCGGC
CTGGCCACCATGATGTCGCCCCGGGAGAGCCTGCTCCGTTACGGGCCGCTGCTGGACTACCTGAACAGCAAGCTGGAACG
GCACGTCGAGGTGGTCCTCGCCTCCTCACAGACGGAGATGCTTGAGCTCCTGCGCACCGGCGGGGTGCAGCTCGGGCTGG
TGGGCAGCCTCGCGTACGTGCAGGGCGCCGACGGCTTCGGCCTGAAGGCGCTGGCGGTGCCCGAGTACCAGGGCGAACCG
ACGCACCGCTCGCTGATCCTGGTGCGCCGCTACAGCGGCCTGGAAGAATTCGCCCACCTGAAGGGACACACGTTTGCCTA
CACCGACCCGGTTTCCGCCACCGGCTGGCTTTATCCGCAGACGCTGGTGCTTGAGCTGAATGAGGCGGTGGAACGCTTCT
TCGACCGGGCGCTCTTCACCGGCACCGACGACAAGGCGATTCAGGCCCTGGACCACGGGCTGGTGGACGGCGCCGCCGTC
AACAGCGTGATCTACGACATGGCGGTCGCTGAGGACCCCGACCTGGCCCGGCGGCTGCGTGCCATCGGCTCATCGGAGCC
GCTCGGATCGCCGCCGGTGGTCGTCTCCCCGACGGTCGGTTCCGAGCTGGTCGCACAGCTGGAGTCTGTCTTCCTTCAGA
TGGGCGAGGATGAGGAGGGACGGGCGGTGCTGCAGAGCTTGCGCCTGGACCGTTTCGTCGCTCCGGATCCCGCCTGGTAC
GAACCGATCAGGCTCATGCTGGAAGAGGTGGAGGCGAGCAAGTGA

Upstream 100 bases:

>100_bases
AAGGCCACCGCGCACCGAGCGTGGTGGCCTTCCTGCTTGCGGGGCCTGTTCATGTCTCTTCCTGACGTGCCAACCATTTG
CCGCCCTGAACGGGCGGCTG

Downstream 100 bases:

>100_bases
GGATGCGGCGGCAGGAGGCGTCAGGCCGGCCGAGGCTGCGCGTTTTCGGCATCCGGGCCAAGCTGATCTCCGTGCTTCTG
GCGCTCACCATTGCGCTGGG

Product: hypothetical protein

Products: 3-phospho-serine [Cytoplasm]; phosphate [Cytoplasm]; alkylphosphonate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MPHSRQVRKNPDEKYQPLARSRWRWMRVRRPLSVLLLAAVVSLWGCASAPQLPEVRLNQLDRTLAAGSVGISPRPVLKVG
LATMMSPRESLLRYGPLLDYLNSKLERHVEVVLASSQTEMLELLRTGGVQLGLVGSLAYVQGADGFGLKALAVPEYQGEP
THRSLILVRRYSGLEEFAHLKGHTFAYTDPVSATGWLYPQTLVLELNEAVERFFDRALFTGTDDKAIQALDHGLVDGAAV
NSVIYDMAVAEDPDLARRLRAIGSSEPLGSPPVVVSPTVGSELVAQLESVFLQMGEDEEGRAVLQSLRLDRFVAPDPAWY
EPIRLMLEEVEASK

Sequences:

>Translated_334_residues
MPHSRQVRKNPDEKYQPLARSRWRWMRVRRPLSVLLLAAVVSLWGCASAPQLPEVRLNQLDRTLAAGSVGISPRPVLKVG
LATMMSPRESLLRYGPLLDYLNSKLERHVEVVLASSQTEMLELLRTGGVQLGLVGSLAYVQGADGFGLKALAVPEYQGEP
THRSLILVRRYSGLEEFAHLKGHTFAYTDPVSATGWLYPQTLVLELNEAVERFFDRALFTGTDDKAIQALDHGLVDGAAV
NSVIYDMAVAEDPDLARRLRAIGSSEPLGSPPVVVSPTVGSELVAQLESVFLQMGEDEEGRAVLQSLRLDRFVAPDPAWY
EPIRLMLEEVEASK
>Mature_333_residues
PHSRQVRKNPDEKYQPLARSRWRWMRVRRPLSVLLLAAVVSLWGCASAPQLPEVRLNQLDRTLAAGSVGISPRPVLKVGL
ATMMSPRESLLRYGPLLDYLNSKLERHVEVVLASSQTEMLELLRTGGVQLGLVGSLAYVQGADGFGLKALAVPEYQGEPT
HRSLILVRRYSGLEEFAHLKGHTFAYTDPVSATGWLYPQTLVLELNEAVERFFDRALFTGTDDKAIQALDHGLVDGAAVN
SVIYDMAVAEDPDLARRLRAIGSSEPLGSPPVVVSPTVGSELVAQLESVFLQMGEDEEGRAVLQSLRLDRFVAPDPAWYE
PIRLMLEEVEASK

Specific function: Probably forms part of a binding-protein-dependent phosphite transporter. Required for oxidation of phosphite to phosphate [H]

COG id: COG3221

COG function: function code P; ABC-type phosphate/phosphonate transport system, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790543, Length=253, Percent_Identity=23.7154150197628, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015168
- InterPro:   IPR005770 [H]

Pfam domain/function: PF09084 NMT1 [H]

EC number: NA

Molecular weight: Translated: 36877; Mature: 36746

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHSRQVRKNPDEKYQPLARSRWRWMRVRRPLSVLLLAAVVSLWGCASAPQLPEVRLNQL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
DRTLAAGSVGISPRPVLKVGLATMMSPRESLLRYGPLLDYLNSKLERHVEVVLASSQTEM
HHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LELLRTGGVQLGLVGSLAYVQGADGFGLKALAVPEYQGEPTHRSLILVRRYSGLEEFAHL
HHHHHHCCCEEEHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHEEEEHHHCCHHHHHHH
KGHTFAYTDPVSATGWLYPQTLVLELNEAVERFFDRALFTGTDDKAIQALDHGLVDGAAV
CCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHH
NSVIYDMAVAEDPDLARRLRAIGSSEPLGSPPVVVSPTVGSELVAQLESVFLQMGEDEEG
HHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHCCCCCHH
RAVLQSLRLDRFVAPDPAWYEPIRLMLEEVEASK
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PHSRQVRKNPDEKYQPLARSRWRWMRVRRPLSVLLLAAVVSLWGCASAPQLPEVRLNQL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
DRTLAAGSVGISPRPVLKVGLATMMSPRESLLRYGPLLDYLNSKLERHVEVVLASSQTEM
HHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LELLRTGGVQLGLVGSLAYVQGADGFGLKALAVPEYQGEPTHRSLILVRRYSGLEEFAHL
HHHHHHCCCEEEHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHEEEEHHHCCHHHHHHH
KGHTFAYTDPVSATGWLYPQTLVLELNEAVERFFDRALFTGTDDKAIQALDHGLVDGAAV
CCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHH
NSVIYDMAVAEDPDLARRLRAIGSSEPLGSPPVVVSPTVGSELVAQLESVFLQMGEDEEG
HHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHCCCCCHH
RAVLQSLRLDRFVAPDPAWYEPIRLMLEEVEASK
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 3-phospho-serine [Periplasm]; phosphite [Periplasm]; H2O; phosphate [Periplasm]; alkylphosphonate [Periplasm] [C]

Specific reaction: H2O + ATP + 3-phospho-serine [Periplasm] = ADP + phosphate + 3-phospho-serine [Cytoplasm] ATP + phosphite [Periplasm] + H2O = phosphite [Cytoplasm] + ADP + phosphate phosphate [Periplasm] + ATP + H2O = ADP + phosphate [Cytoplasm] + phosphate [Cytoplasm] A

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9791102 [H]