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The map label for this gene is nreC [H]

Identifier: 51894355

GI number: 51894355

Start: 3434840

End: 3435451

Strand: Reverse

Name: nreC [H]

Synonym: STH3220

Alternate gene names: 51894355

Gene position: 3435451-3434840 (Counterclockwise)

Preceding gene: 51894356

Following gene: 51894354

Centisome position: 96.34

GC content: 63.73

Gene sequence:

>612_bases
ATGCGCATCTTGATCGCCGATGATCATCGGGTCGTCAGGACGGGGCTGCGGATGCTGCTGGAGAGCCATCCCGACTTCGA
AGTGGTCGGGGAGGCGTCCAGCGGGCCGGAGACGGTGCAGAAGGCGCAGGAGTTGCGGCCGGAGCTGGTCATCCTGGACC
TTTCCATGCCCGATGGGAACGGCCTTCTGTACCTGCGCCAGCTTTCGGAGATGACCCGGGTGCTGGTGCTGACGATGCAC
GACGATCCCGCTTACGTGCGGCAGGTGATTCAGGCGGGCGGCAGCGGTTACGTCCTCAAAGAGGCAGCCGACGTGGAGCT
GTTCTCGGCCATCCGCGCCGTGCTTTCGGGCCAGACGTACATCTATCCCACCCTGGCCGCCAAGCTCGTGGAGGAGAAGG
CGGGCGGCGAGCGCAAGTCGGTGCCGCTCAGCCCCCGGGAGCTGGAGGTGCTCCGCCTGGTGGCCCTGGGCCATACCAAC
CAGGAAATTGCTTTGCAGCTGAACGTGAGCGTACGAACGGTTGAAACTTACAAGACCCGGATCTGTGAGAAACTCGGCGT
CTACACCCGGTCGGAGATGGTTCGCTACGCCCTGGAGCACAAACTGACCTGA

Upstream 100 bases:

>100_bases
CGGCTGGCGCTGGTGAGTGGCCGCATGACCATCGAATCCAGTCCGGAAAGCGGCACCACCCTGTTTATCGCGGTCCCGCG
CGAGAAGGAGGACGAGTCGG

Downstream 100 bases:

>100_bases
TCCGCACCATCGGCAGCCGTGTCCGGGAATTCCCGGACACGGTGTACGCGAGGCTACGGATACACGGAAAGGTCGTTCGA
ATGTACGATTACACTGTCTC

Product: two-component response regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MRILIADDHRVVRTGLRMLLESHPDFEVVGEASSGPETVQKAQELRPELVILDLSMPDGNGLLYLRQLSEMTRVLVLTMH
DDPAYVRQVIQAGGSGYVLKEAADVELFSAIRAVLSGQTYIYPTLAAKLVEEKAGGERKSVPLSPRELEVLRLVALGHTN
QEIALQLNVSVRTVETYKTRICEKLGVYTRSEMVRYALEHKLT

Sequences:

>Translated_203_residues
MRILIADDHRVVRTGLRMLLESHPDFEVVGEASSGPETVQKAQELRPELVILDLSMPDGNGLLYLRQLSEMTRVLVLTMH
DDPAYVRQVIQAGGSGYVLKEAADVELFSAIRAVLSGQTYIYPTLAAKLVEEKAGGERKSVPLSPRELEVLRLVALGHTN
QEIALQLNVSVRTVETYKTRICEKLGVYTRSEMVRYALEHKLT
>Mature_203_residues
MRILIADDHRVVRTGLRMLLESHPDFEVVGEASSGPETVQKAQELRPELVILDLSMPDGNGLLYLRQLSEMTRVLVLTMH
DDPAYVRQVIQAGGSGYVLKEAADVELFSAIRAVLSGQTYIYPTLAAKLVEEKAGGERKSVPLSPRELEVLRLVALGHTN
QEIALQLNVSVRTVETYKTRICEKLGVYTRSEMVRYALEHKLT

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=209, Percent_Identity=35.8851674641148, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI1790102, Length=193, Percent_Identity=36.7875647668394, Blast_Score=120, Evalue=5e-29,
Organism=Escherichia coli, GI1788712, Length=207, Percent_Identity=29.951690821256, Blast_Score=103, Evalue=6e-24,
Organism=Escherichia coli, GI1788546, Length=202, Percent_Identity=34.1584158415842, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI1786747, Length=200, Percent_Identity=28.5, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1788521, Length=195, Percent_Identity=35.3846153846154, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1787473, Length=182, Percent_Identity=36.2637362637363, Blast_Score=97, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 22671; Mature: 22671

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILIADDHRVVRTGLRMLLESHPDFEVVGEASSGPETVQKAQELRPELVILDLSMPDGN
CEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEEEECCCCC
GLLYLRQLSEMTRVLVLTMHDDPAYVRQVIQAGGSGYVLKEAADVELFSAIRAVLSGQTY
CEEHHHHHHHHHEEEEEEECCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCCE
IYPTLAAKLVEEKAGGERKSVPLSPRELEVLRLVALGHTNQEIALQLNVSVRTVETYKTR
EHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEEEEEEHHHHHHH
ICEKLGVYTRSEMVRYALEHKLT
HHHHHCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRILIADDHRVVRTGLRMLLESHPDFEVVGEASSGPETVQKAQELRPELVILDLSMPDGN
CEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEEEECCCCC
GLLYLRQLSEMTRVLVLTMHDDPAYVRQVIQAGGSGYVLKEAADVELFSAIRAVLSGQTY
CEEHHHHHHHHHEEEEEEECCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCCE
IYPTLAAKLVEEKAGGERKSVPLSPRELEVLRLVALGHTNQEIALQLNVSVRTVETYKTR
EHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEEEEEEHHHHHHH
ICEKLGVYTRSEMVRYALEHKLT
HHHHHCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]