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The map label for this gene is fusA [H]

Identifier: 51894275

GI number: 51894275

Start: 3340397

End: 3342484

Strand: Reverse

Name: fusA [H]

Synonym: STH3140

Alternate gene names: 51894275

Gene position: 3342484-3340397 (Counterclockwise)

Preceding gene: 51894276

Following gene: 51894272

Centisome position: 93.73

GC content: 66.86

Gene sequence:

>2088_bases
ATGGACTTGAGACGATTTGCTGTCGAGAAGGTGCGGAACGTTGCCCTCATTGCCCACGGCGGCGCCGGGAAGACCTCCCT
GGCTGAGGCCATGCTGTTCACGGCCGGGGCAACGGATCGGCTTGGGCGCGTCGACGAGGGCAATACGGTGATGGACTACG
ATCCCGAGGAGATCCGGCGGAAGGTCTCCATCTCCATGGGCATTGCGCCGCTGGAGTGGAAGGGCCACAAGTTCAACCTG
CTGGATACTCCCGGGTATTTTGATTTTGTCGGCGAGGTCAAGGCGGCGCTGCGGGTTGTGGAGACGGCTGTTCTGGTGGT
GGACGCGGTGGCCGGCATCGAGGTCGGCGCGGAGCTGACCTACGAGCACGCCCGGAAGGCCGGGGTCTCCCGGATGATCG
TGATCAACAAGATGGACCGGGAGAACGCCAACTTCCGCAAGACCCTGAGCGCGTTGGAGGAGGCCTGGGGGCGGGGCGTC
GTGGCGCTGCACCTGCCCATCGGCGCCGAGGCCAGCTTCTCCGGCGTCGTCGACGTGGTCAGGCAGAAGGCCTACACGTT
CTCCGGCAAGCAGGTGAAGGAAGAAGCGGTGCCCGCCGAGTTCGACGGGCAGGTCGCGGAGATCCGCGAGAAGCTGATGG
AACTGGCGGCCGAGGCCGACGATGAGCTCACCATGAAGTTCCTCGAGGAGGGCGAGCTCACCCAGGAGGAGCTGGAGCGG
GGCCTGCGGCTGGGCGTGGTGAAGGGCGACATCGTCCCGGTCTTCGTCGCGGCCGCGGCCAGGAACATCGGCGTCAGCGC
CCTGATGGACGCCATCGTCGCCTACGGGCCGTCTCCGGCAGACCGGGGCGACCTGGTCGGCCAGACGCCTGACGGCGAGC
CCGTCAGCCAGCCCATCGGCGAGAACCAGCCCTTCAGCGCGCTGGTGTTCAAGACCACCGCGGACCCGTTCGTCGGCCGC
ATGACGGTCATGCGGGTCTTCAACGGCAAGATCACCAGCGACCAGACGGTGTACAACGTGACGCGGGGCCGAAGCGAGCG
CATCGGCAACATCTTCATCCCCAAGGGGAAGGGGCAGGAGCCGGTCACCGAGGCCGGCCCGGGCGACATCATCGCCGTCG
CGAAGCTGGCCGTCACCCAGACCAACGACAGCCTGGGCGAAGAGGCGAATCCGCTGGTCCTGGAGCCCGTTGACTTCCCC
GCCCCGGTCTACTCCGTTGCGGTGAGCCCGAAGTCCAAGGGCGACGAGGAGAAGATCGGCTCCGGTCTGCAGCGGCTGGC
CGAGGAGGACGCGACCTTCACGGTGCGGCGTGACCCGGTCACCCACGAGACGATCCTCTCCGGCCTCGGCGAGACCCACG
TGGACGTCATGATCGAGCGGCTGAAGCGGAAGTTCGGTGTGGAGGCCGTCCTGAGCGAGCCGAAGGTCGCGTACAAGGAG
ACCATCCGCGGCAGGGCGCAGGGCGAGTACAAGCACAAGAAGCAGACCGGCGGCCGCGGCCAGTACGGCCATTGCAAGAT
CGAGATCGAGCCGCTGCCCGAAGGCGAGTACGAGTTCGTCGACAAGATCTTCGCCGGCGCGATCCCGCTCAACTTCCGTC
CGGCCGTCGACAAGGGCGTGCAGGAGACCATGGCCGAGGGCGTCCTGGCCGGCTACCCGGTGACGGGCGTCCGCTGCACC
CTGCTGGACGGCTCCTACCATGAGGTCGACTCCTCCGAAATGGCCTTCAAGATCGCCGCCCGCAACGCGTTCCGGCAGGC
GTTCATGAACGCGAAGCCGATCCTGCTGGAGCCGATCATGCGGCTGGAGGTTGTCGTGCCCGAGTCCTACATGGGCGACA
TCATGGGCGACCTGAACAAGAAGCGCGGCCGCATCGCAGGCATGGAGCCCACCGGCGACGGCAAGCAGATCATCAAGGCG
ATGGTCCCGCTCGCCGAGATGCACCGGTACGCCATCGACCTCCGGTCGATGACCCAGGGCCGCGGCCAGTTCACCATGGA
GTTCGACCACTACGAGGAGGCCCCGGCCCAGGTGGCCAAGGCGGTCATCGATGCCGCCCAGGCCAGCCGCAAGGAGGAGT
CCGAGTAG

Upstream 100 bases:

>100_bases
GCGGTGCGCCTGTCGCCCCTGCGTCGCCGCCTGCAAGTCCGAACCGTTTTGCCTGGGGGCCCCTCGGCTGAGCGCAGTTC
CATCAACCGTTGAGGAGGAG

Downstream 100 bases:

>100_bases
ACGGGCTCGGGCCCGTTACGGCAGCGCCTCCAGCTGGACCAGCCGTAGCACCTCCCCGGTCTGCGCGTCGAGGACCAGCC
GGATCCGCTGCCCGGCCGGC

Product: protein translation elongation factor G

Products: NA

Alternate protein names: EF-G [H]

Number of amino acids: Translated: 695; Mature: 695

Protein sequence:

>695_residues
MDLRRFAVEKVRNVALIAHGGAGKTSLAEAMLFTAGATDRLGRVDEGNTVMDYDPEEIRRKVSISMGIAPLEWKGHKFNL
LDTPGYFDFVGEVKAALRVVETAVLVVDAVAGIEVGAELTYEHARKAGVSRMIVINKMDRENANFRKTLSALEEAWGRGV
VALHLPIGAEASFSGVVDVVRQKAYTFSGKQVKEEAVPAEFDGQVAEIREKLMELAAEADDELTMKFLEEGELTQEELER
GLRLGVVKGDIVPVFVAAAARNIGVSALMDAIVAYGPSPADRGDLVGQTPDGEPVSQPIGENQPFSALVFKTTADPFVGR
MTVMRVFNGKITSDQTVYNVTRGRSERIGNIFIPKGKGQEPVTEAGPGDIIAVAKLAVTQTNDSLGEEANPLVLEPVDFP
APVYSVAVSPKSKGDEEKIGSGLQRLAEEDATFTVRRDPVTHETILSGLGETHVDVMIERLKRKFGVEAVLSEPKVAYKE
TIRGRAQGEYKHKKQTGGRGQYGHCKIEIEPLPEGEYEFVDKIFAGAIPLNFRPAVDKGVQETMAEGVLAGYPVTGVRCT
LLDGSYHEVDSSEMAFKIAARNAFRQAFMNAKPILLEPIMRLEVVVPESYMGDIMGDLNKKRGRIAGMEPTGDGKQIIKA
MVPLAEMHRYAIDLRSMTQGRGQFTMEFDHYEEAPAQVAKAVIDAAQASRKEESE

Sequences:

>Translated_695_residues
MDLRRFAVEKVRNVALIAHGGAGKTSLAEAMLFTAGATDRLGRVDEGNTVMDYDPEEIRRKVSISMGIAPLEWKGHKFNL
LDTPGYFDFVGEVKAALRVVETAVLVVDAVAGIEVGAELTYEHARKAGVSRMIVINKMDRENANFRKTLSALEEAWGRGV
VALHLPIGAEASFSGVVDVVRQKAYTFSGKQVKEEAVPAEFDGQVAEIREKLMELAAEADDELTMKFLEEGELTQEELER
GLRLGVVKGDIVPVFVAAAARNIGVSALMDAIVAYGPSPADRGDLVGQTPDGEPVSQPIGENQPFSALVFKTTADPFVGR
MTVMRVFNGKITSDQTVYNVTRGRSERIGNIFIPKGKGQEPVTEAGPGDIIAVAKLAVTQTNDSLGEEANPLVLEPVDFP
APVYSVAVSPKSKGDEEKIGSGLQRLAEEDATFTVRRDPVTHETILSGLGETHVDVMIERLKRKFGVEAVLSEPKVAYKE
TIRGRAQGEYKHKKQTGGRGQYGHCKIEIEPLPEGEYEFVDKIFAGAIPLNFRPAVDKGVQETMAEGVLAGYPVTGVRCT
LLDGSYHEVDSSEMAFKIAARNAFRQAFMNAKPILLEPIMRLEVVVPESYMGDIMGDLNKKRGRIAGMEPTGDGKQIIKA
MVPLAEMHRYAIDLRSMTQGRGQFTMEFDHYEEAPAQVAKAVIDAAQASRKEESE
>Mature_695_residues
MDLRRFAVEKVRNVALIAHGGAGKTSLAEAMLFTAGATDRLGRVDEGNTVMDYDPEEIRRKVSISMGIAPLEWKGHKFNL
LDTPGYFDFVGEVKAALRVVETAVLVVDAVAGIEVGAELTYEHARKAGVSRMIVINKMDRENANFRKTLSALEEAWGRGV
VALHLPIGAEASFSGVVDVVRQKAYTFSGKQVKEEAVPAEFDGQVAEIREKLMELAAEADDELTMKFLEEGELTQEELER
GLRLGVVKGDIVPVFVAAAARNIGVSALMDAIVAYGPSPADRGDLVGQTPDGEPVSQPIGENQPFSALVFKTTADPFVGR
MTVMRVFNGKITSDQTVYNVTRGRSERIGNIFIPKGKGQEPVTEAGPGDIIAVAKLAVTQTNDSLGEEANPLVLEPVDFP
APVYSVAVSPKSKGDEEKIGSGLQRLAEEDATFTVRRDPVTHETILSGLGETHVDVMIERLKRKFGVEAVLSEPKVAYKE
TIRGRAQGEYKHKKQTGGRGQYGHCKIEIEPLPEGEYEFVDKIFAGAIPLNFRPAVDKGVQETMAEGVLAGYPVTGVRCT
LLDGSYHEVDSSEMAFKIAARNAFRQAFMNAKPILLEPIMRLEVVVPESYMGDIMGDLNKKRGRIAGMEPTGDGKQIIKA
MVPLAEMHRYAIDLRSMTQGRGQFTMEFDHYEEAPAQVAKAVIDAAQASRKEESE

Specific function: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=693, Percent_Identity=33.6219336219336, Blast_Score=408, Evalue=1e-114,
Organism=Homo sapiens, GI19923640, Length=721, Percent_Identity=29.6809986130374, Blast_Score=322, Evalue=6e-88,
Organism=Homo sapiens, GI25306283, Length=451, Percent_Identity=29.9334811529933, Blast_Score=191, Evalue=3e-48,
Organism=Homo sapiens, GI25306287, Length=290, Percent_Identity=35.1724137931034, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI4503483, Length=479, Percent_Identity=24.6346555323591, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI157426893, Length=160, Percent_Identity=33.125, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI94966754, Length=134, Percent_Identity=29.8507462686567, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1789738, Length=700, Percent_Identity=43.1428571428571, Blast_Score=558, Evalue=1e-160,
Organism=Escherichia coli, GI1790835, Length=508, Percent_Identity=26.5748031496063, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI48994988, Length=136, Percent_Identity=36.0294117647059, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1788922, Length=156, Percent_Identity=28.8461538461538, Blast_Score=63, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17533571, Length=701, Percent_Identity=32.0970042796006, Blast_Score=382, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17556745, Length=698, Percent_Identity=24.785100286533, Blast_Score=228, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17506493, Length=823, Percent_Identity=23.3292831105711, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71988819, Length=578, Percent_Identity=22.8373702422145, Blast_Score=85, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71988811, Length=578, Percent_Identity=22.8373702422145, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17557151, Length=157, Percent_Identity=29.9363057324841, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6323098, Length=694, Percent_Identity=33.1412103746398, Blast_Score=384, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6322359, Length=792, Percent_Identity=27.7777777777778, Blast_Score=289, Evalue=8e-79,
Organism=Saccharomyces cerevisiae, GI6324707, Length=812, Percent_Identity=23.3990147783251, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6320593, Length=812, Percent_Identity=23.3990147783251, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24582462, Length=697, Percent_Identity=34.4332855093257, Blast_Score=422, Evalue=1e-118,
Organism=Drosophila melanogaster, GI221458488, Length=713, Percent_Identity=29.1725105189341, Blast_Score=275, Evalue=1e-73,
Organism=Drosophila melanogaster, GI24585711, Length=482, Percent_Identity=24.896265560166, Blast_Score=93, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24585713, Length=482, Percent_Identity=24.896265560166, Blast_Score=93, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24585709, Length=482, Percent_Identity=24.6887966804979, Blast_Score=93, Evalue=6e-19,
Organism=Drosophila melanogaster, GI78706572, Length=163, Percent_Identity=33.1288343558282, Blast_Score=79, Evalue=8e-15,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR004540
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 75726; Mature: 75726

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLRRFAVEKVRNVALIAHGGAGKTSLAEAMLFTAGATDRLGRVDEGNTVMDYDPEEIRR
CCHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHCCCCHHCCCCCCCCEEECCCHHHHHH
KVSISMGIAPLEWKGHKFNLLDTPGYFDFVGEVKAALRVVETAVLVVDAVAGIEVGAELT
HHHHHCCCCEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
YEHARKAGVSRMIVINKMDRENANFRKTLSALEEAWGRGVVALHLPIGAEASFSGVVDVV
HHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHH
RQKAYTFSGKQVKEEAVPAEFDGQVAEIREKLMELAAEADDELTMKFLEEGELTQEELER
HHHHHCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHC
GLRLGVVKGDIVPVFVAAAARNIGVSALMDAIVAYGPSPADRGDLVGQTPDGEPVSQPIG
CCEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
ENQPFSALVFKTTADPFVGRMTVMRVFNGKITSDQTVYNVTRGRSERIGNIFIPKGKGQE
CCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCEEEEECCCCCC
PVTEAGPGDIIAVAKLAVTQTNDSLGEEANPLVLEPVDFPAPVYSVAVSPKSKGDEEKIG
CCCCCCCCCEEEEEEEEEEECCCCCCCCCCCEEEECCCCCCCEEEEEECCCCCCCHHHHH
SGLQRLAEEDATFTVRRDPVTHETILSGLGETHVDVMIERLKRKFGVEAVLSEPKVAYKE
HHHHHHHHCCCEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHCCCCHHHHH
TIRGRAQGEYKHKKQTGGRGQYGHCKIEIEPLPEGEYEFVDKIFAGAIPLNFRPAVDKGV
HHCCCCCCCHHHHHCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHH
QETMAEGVLAGYPVTGVRCTLLDGSYHEVDSSEMAFKIAARNAFRQAFMNAKPILLEPIM
HHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHH
RLEVVVPESYMGDIMGDLNKKRGRIAGMEPTGDGKQIIKAMVPLAEMHRYAIDLRSMTQG
HEEEECCHHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
RGQFTMEFDHYEEAPAQVAKAVIDAAQASRKEESE
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDLRRFAVEKVRNVALIAHGGAGKTSLAEAMLFTAGATDRLGRVDEGNTVMDYDPEEIRR
CCHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHCCCCHHCCCCCCCCEEECCCHHHHHH
KVSISMGIAPLEWKGHKFNLLDTPGYFDFVGEVKAALRVVETAVLVVDAVAGIEVGAELT
HHHHHCCCCEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
YEHARKAGVSRMIVINKMDRENANFRKTLSALEEAWGRGVVALHLPIGAEASFSGVVDVV
HHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHH
RQKAYTFSGKQVKEEAVPAEFDGQVAEIREKLMELAAEADDELTMKFLEEGELTQEELER
HHHHHCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHC
GLRLGVVKGDIVPVFVAAAARNIGVSALMDAIVAYGPSPADRGDLVGQTPDGEPVSQPIG
CCEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
ENQPFSALVFKTTADPFVGRMTVMRVFNGKITSDQTVYNVTRGRSERIGNIFIPKGKGQE
CCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCEEEEECCCCCC
PVTEAGPGDIIAVAKLAVTQTNDSLGEEANPLVLEPVDFPAPVYSVAVSPKSKGDEEKIG
CCCCCCCCCEEEEEEEEEEECCCCCCCCCCCEEEECCCCCCCEEEEEECCCCCCCHHHHH
SGLQRLAEEDATFTVRRDPVTHETILSGLGETHVDVMIERLKRKFGVEAVLSEPKVAYKE
HHHHHHHHCCCEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHCCCCHHHHH
TIRGRAQGEYKHKKQTGGRGQYGHCKIEIEPLPEGEYEFVDKIFAGAIPLNFRPAVDKGV
HHCCCCCCCHHHHHCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHH
QETMAEGVLAGYPVTGVRCTLLDGSYHEVDSSEMAFKIAARNAFRQAFMNAKPILLEPIM
HHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHH
RLEVVVPESYMGDIMGDLNKKRGRIAGMEPTGDGKQIIKAMVPLAEMHRYAIDLRSMTQG
HEEEECCHHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
RGQFTMEFDHYEEAPAQVAKAVIDAAQASRKEESE
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA