Click here to switch to the map view.

The map label for this gene is 51894269

Identifier: 51894269

GI number: 51894269

Start: 3335716

End: 3336777

Strand: Reverse

Name: 51894269

Synonym: STH3134

Alternate gene names: NA

Gene position: 3336777-3335716 (Counterclockwise)

Preceding gene: 51894270

Following gene: 51894268

Centisome position: 93.57

GC content: 68.74

Gene sequence:

>1062_bases
GTGGGTTGGAATGAGCTGGTGTCCCGCGCGGAGAGCCGCTGGATGGAGGGAACCGGACCGCACGCCGACATCGTGCTCTC
TTCCCGGATCCGGCTGGCCCGCAACCTGGATGACCTGCCCTTCCCGCAGCGGATGTCCGAACCCGACACCGAGCGGCTTC
TGCAGGCCGCGGAGGCGGGGGTCCGCGAGATCAACCTGGTCGGCTTCCCGTCCCGGGTGGAACTGTATCGGCTGGCCGAC
ACCACGCCGCTGGACCGGCAGATCCTGGTCGAGAAGCACCTGATCAGCCCGCAGCAGTCCAAGGAGGTCATGGCCAAGGC
CGTGGCCATTTCCGAGGACGAGGCCATCTCCATCATGGTCAACGAGGAGGACCACCTGCGCATCCAGGTGCTGGCCTCCG
GGCTGCAGCTGCAGGAGGCCTGGCGGGTGGCGTCCCAGGTGGACGACGCCCTGGAGCAGCGGCTCCAGTTCGCGTTTGAC
GAGCAGCTGGGCTATCTCACGGCCTGCCCGACCAACGTAGGCACGGGGCTCCGGGCCTCGGTGATGATGCACCTGCCGGC
CCTGGTGCTGACGCAGCAGGCCGGTCGGCTCTTCCACAACCTCTCGCAGTTGGGCCTCGTGGTACGGGGACTTTACGGCG
AGGGCACGGAGGCGGCCGGGCAGATCTTCCAGATCTCCAACCAGACCTCCCTCGGGAAGGCCGAGGAGGAGATCATCGCG
AACCTGGAGGCCATCGCCCGGACCGTGATCGACACGGAGGAGCAGGCCCGCCGCCATCTCTACGGGGAGATGCGGCTGCA
GATCGAGGACCGGGTCTCCCGGGCGTACGGCATCCTCACCACCGCCCGGATGATCAGCTCGGAGGAGGCGATGCGCCTGC
TCTCGGACGTACGCCTGGGCGTTGCCCTGGGGGTCGTGCCGAAGATCGACTACCGCATCCTCAACGAGTTGCTCGTGGCG
ATGCAGCCCGCGTGCCTGCAGCGGCAGGCGGGGCGGGAGCTGAACCCGCTGGAGCGGGACGTGCGGCGGGCGGCGCTGAT
CCGGGCGCGCCTTTCCGCCTGA

Upstream 100 bases:

>100_bases
CTGGCCTCCGCCGTGCAGGGCGAGCGCTACGAGGAGGCCGCCCGGATCCGGGACCAGATCCGGGCGCTGGAGGCGGAGAT
CGCCGCAGGGGGTGACAACG

Downstream 100 bases:

>100_bases
CCGGCCGGCCGTATCGCACCGCAGGGCGCAGCGGTCCCAATCGGTAAGTGTGCGGCGAGGGCGATGCCTCGCCACGTGGT
TCCGGAATAAACAGATGGAT

Product: ATP:guanido phosphotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MGWNELVSRAESRWMEGTGPHADIVLSSRIRLARNLDDLPFPQRMSEPDTERLLQAAEAGVREINLVGFPSRVELYRLAD
TTPLDRQILVEKHLISPQQSKEVMAKAVAISEDEAISIMVNEEDHLRIQVLASGLQLQEAWRVASQVDDALEQRLQFAFD
EQLGYLTACPTNVGTGLRASVMMHLPALVLTQQAGRLFHNLSQLGLVVRGLYGEGTEAAGQIFQISNQTSLGKAEEEIIA
NLEAIARTVIDTEEQARRHLYGEMRLQIEDRVSRAYGILTTARMISSEEAMRLLSDVRLGVALGVVPKIDYRILNELLVA
MQPACLQRQAGRELNPLERDVRRAALIRARLSA

Sequences:

>Translated_353_residues
MGWNELVSRAESRWMEGTGPHADIVLSSRIRLARNLDDLPFPQRMSEPDTERLLQAAEAGVREINLVGFPSRVELYRLAD
TTPLDRQILVEKHLISPQQSKEVMAKAVAISEDEAISIMVNEEDHLRIQVLASGLQLQEAWRVASQVDDALEQRLQFAFD
EQLGYLTACPTNVGTGLRASVMMHLPALVLTQQAGRLFHNLSQLGLVVRGLYGEGTEAAGQIFQISNQTSLGKAEEEIIA
NLEAIARTVIDTEEQARRHLYGEMRLQIEDRVSRAYGILTTARMISSEEAMRLLSDVRLGVALGVVPKIDYRILNELLVA
MQPACLQRQAGRELNPLERDVRRAALIRARLSA
>Mature_352_residues
GWNELVSRAESRWMEGTGPHADIVLSSRIRLARNLDDLPFPQRMSEPDTERLLQAAEAGVREINLVGFPSRVELYRLADT
TPLDRQILVEKHLISPQQSKEVMAKAVAISEDEAISIMVNEEDHLRIQVLASGLQLQEAWRVASQVDDALEQRLQFAFDE
QLGYLTACPTNVGTGLRASVMMHLPALVLTQQAGRLFHNLSQLGLVVRGLYGEGTEAAGQIFQISNQTSLGKAEEEIIAN
LEAIARTVIDTEEQARRHLYGEMRLQIEDRVSRAYGILTTARMISSEEAMRLLSDVRLGVALGVVPKIDYRILNELLVAM
QPACLQRQAGRELNPLERDVRRAALIRARLSA

Specific function: Unknown

COG id: COG3869

COG function: function code E; Arginine kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 phosphagen kinase C-terminal domain

Homologues:

Organism=Homo sapiens, GI66346730, Length=252, Percent_Identity=30.5555555555556, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI10334859, Length=252, Percent_Identity=30.5555555555556, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI153252003, Length=253, Percent_Identity=28.4584980237154, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI153251984, Length=253, Percent_Identity=28.4584980237154, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI153251982, Length=253, Percent_Identity=28.4584980237154, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI310110654, Length=251, Percent_Identity=26.2948207171315, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI21536286, Length=251, Percent_Identity=26.2948207171315, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI21536288, Length=234, Percent_Identity=27.7777777777778, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI310110652, Length=156, Percent_Identity=30.7692307692308, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI310110650, Length=151, Percent_Identity=31.1258278145695, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17509681, Length=257, Percent_Identity=26.4591439688716, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17507069, Length=257, Percent_Identity=26.0700389105058, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17560974, Length=255, Percent_Identity=26.2745098039216, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17511011, Length=249, Percent_Identity=27.3092369477912, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI71990551, Length=245, Percent_Identity=27.3469387755102, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI32566409, Length=245, Percent_Identity=27.3469387755102, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24661332, Length=254, Percent_Identity=28.740157480315, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI161082598, Length=236, Percent_Identity=29.6610169491525, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI221331031, Length=236, Percent_Identity=29.6610169491525, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24661348, Length=236, Percent_Identity=29.6610169491525, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24661344, Length=236, Percent_Identity=29.6610169491525, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24661340, Length=236, Percent_Identity=29.6610169491525, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24661336, Length=236, Percent_Identity=29.6610169491525, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24647265, Length=253, Percent_Identity=30.4347826086957, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y3134_SYMTH (Q67JN4)

Other databases:

- EMBL:   AP006840
- RefSeq:   YP_076960.1
- ProteinModelPortal:   Q67JN4
- SMR:   Q67JN4
- GeneID:   2980208
- GenomeReviews:   AP006840_GR
- KEGG:   sth:STH3134
- HOGENOM:   HBG302740
- OMA:   DRVFRSY
- ProtClustDB:   PRK01059
- BioCyc:   STHE292459:STH3134-MONOMER
- HAMAP:   MF_00602
- InterPro:   IPR000749
- InterPro:   IPR022414
- InterPro:   IPR022415
- InterPro:   IPR014746
- Gene3D:   G3DSA:3.30.590.10
- PANTHER:   PTHR11547

Pfam domain/function: PF00217 ATP-gua_Ptrans

EC number: NA

Molecular weight: Translated: 39406; Mature: 39275

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00112 PHOSPHAGEN_KINASE; PS51510 PHOSPHAGEN_KINASE_C

Important sites: BINDING 93-93 BINDING 127-127

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGWNELVSRAESRWMEGTGPHADIVLSSRIRLARNLDDLPFPQRMSEPDTERLLQAAEAG
CCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCC
VREINLVGFPSRVELYRLADTTPLDRQILVEKHLISPQQSKEVMAKAVAISEDEAISIMV
HHEEEEECCCCHHHEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEE
NEEDHLRIQVLASGLQLQEAWRVASQVDDALEQRLQFAFDEQLGYLTACPTNVGTGLRAS
CCCCCEEEEEHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHH
VMMHLPALVLTQQAGRLFHNLSQLGLVVRGLYGEGTEAAGQIFQISNQTSLGKAEEEIIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCEEEECCCCCCCHHHHHHHH
NLEAIARTVIDTEEQARRHLYGEMRLQIEDRVSRAYGILTTARMISSEEAMRLLSDVRLG
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VALGVVPKIDYRILNELLVAMQPACLQRQAGRELNPLERDVRRAALIRARLSA
HHHCCCCCHHHHHHHHHHHHHCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GWNELVSRAESRWMEGTGPHADIVLSSRIRLARNLDDLPFPQRMSEPDTERLLQAAEAG
CHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCC
VREINLVGFPSRVELYRLADTTPLDRQILVEKHLISPQQSKEVMAKAVAISEDEAISIMV
HHEEEEECCCCHHHEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEE
NEEDHLRIQVLASGLQLQEAWRVASQVDDALEQRLQFAFDEQLGYLTACPTNVGTGLRAS
CCCCCEEEEEHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHH
VMMHLPALVLTQQAGRLFHNLSQLGLVVRGLYGEGTEAAGQIFQISNQTSLGKAEEEIIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCEEEECCCCCCCHHHHHHHH
NLEAIARTVIDTEEQARRHLYGEMRLQIEDRVSRAYGILTTARMISSEEAMRLLSDVRLG
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VALGVVPKIDYRILNELLVAMQPACLQRQAGRELNPLERDVRRAALIRARLSA
HHHCCCCCHHHHHHHHHHHHHCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA