Click here to switch to the map view.

The map label for this gene is clpB [H]

Identifier: 51894268

GI number: 51894268

Start: 3333098

End: 3335599

Strand: Reverse

Name: clpB [H]

Synonym: STH3133

Alternate gene names: 51894268

Gene position: 3335599-3333098 (Counterclockwise)

Preceding gene: 51894269

Following gene: 51894267

Centisome position: 93.54

GC content: 67.47

Gene sequence:

>2502_bases
ATGTTCAGCCGCTACACGGAACGGGCTCAGCGGGTCATCGTGCTGGCCCAGGATGAGGCTCGGCGTTTGAATTACGACTA
CGTCGGCACAGAGCATCTGCTCCTGGGACTGATTCGCGAGGGCGAGGGCATCGCCGCCAAGGCGCTCCAGTCGCTGGGCA
TCCAGCTGGAGCAGGTGCGGGCCGAGGTCGAGAAGATGATCGGCAAGGGCTCCGCCTCGTCCCGGGGTGAGATCGGCTTC
ACGCCCAGGGCCAAGAAGGTGATGGTGGAGCTGGCCATCGAAGAGGCGCGGCTCCTGGGGCATAACTACGTGGGCACGGA
GCACATCCTGCTCGGCCTCATCCGGGAGGGCGAGGGCGTGGCTGCCCAGGTGCTGCAGAACCTGGGGGCGGACCTGGAGC
GGGTGCGCAACCAGGTGATCCACCTGCTCGGCGGGGTGCCCCATCCGCCCGCCGGCTCCTCCATGCCGGGATCGGCCAAG
GTCAAGGGGCCCAAGACCAGCACCTCCACGCTGGACCAGTTCGGCCGCGACCTGAATCAGATGGCCCGCGACGGCAAGCT
GGATCCGGTCATCGGCCGGGAGAAGGAGATCGAGCGGGTCATCCAGATTCTCACCCGACGCACCAAGAACAACCCGGTGC
TGATCGGCGAGCCCGGCGTGGGCAAGACCGCCATCGCCGAGGGCCTGGCCCAGCGCATCGTCGACGGCCGGGTGCCGGAG
ATCCTGAAGGACAAGCGGGTCGTCGCCCTGGACCTGGCCTCGCTGGTCGCGGGCTCCAAATACCGGGGCGAGTTTGAGGA
GCGGCTCAAGAAGGTGCTGGAGGAGATCCGCAACGCCGGCAACGTCATCCTCTTCATCGACGAACTGCACACCATCATCG
GCGCCGGCGCAGCGGAGGGCGCGATCGACGCGTCCAACATCCTGAAGCCGGCCCTGGCCCGCGGCGAGTTGCAGGCCATC
GGCGCGACCACCATCGACGAGTACCGCAAGTACGTGGAGAAGGACGCGGCCCTGGAGCGCCGCTTCCAGCCGGTGATGGT
CGAGGAGCCGAGCCCCGAGGACGCCATCCAGATCCTGAAGGGGCTGCGCGACCGGTACGAGGCCCACCACCGGGTCGAGA
TCACCGACGCCGCGATCGAGGCCGCAGTGCGGCTCTCCGACCGCTACGTCACCGACCGGTTCCTGCCCGACAAGGCCGTC
GACCTGATCGACGAGGCCGCCTCCCGCGTCCGGCTCTCCACCTTCGTGGCACCGCCCAACCTGAAGGAGCTGGAGGATAA
GCTGGAGGAGGTGCGCAAGGAGAAGGAGGCCGCCGTCCAGGGGCAGGAGTTCGAGAAGGCCGCGCGCCTCCGGGACAAGG
AGACCAAGCTGAAGGAGGAGCTGGAGCGGCAGAAGAACGAGTGGCAGCAGAAGAAGGTCACGGCGAAGTGCGTCGTGAAC
GAGGAGGACATCGCCACCATCGTCTCTCAGTGGACGGGCATCCCCGCGACAAAGCTGACGATGGACGAGTCCCAGCGGCT
GCTCAACCTGGAGAAGGTGCTGCACGAGAAGGTGGTCGGCCAGGACGAGGCGGTGGCGGCGGTGGCCCGGGCCATCCGGC
GGGCCCGCGCCGGCCTGAAGGATCCGAAGCGGCCCATCGGCTCCTTCATCTTCCTGGGCCCGACGGGCACGGGCAAGACC
CACCTGGCCAAGGCCCTGGCGGAGGCGCTCTTCGGCGACGAGGACGCGATGGTCCGCATCGACATGTCCGAGTATATGGA
GCGGCACACCACCTCCCGGCTGGTGGGCGCGCCGCCCGGGTACGTGGGGTACGAGGAGGGCGGTCAGCTGACCGAGGCCG
TCCGGCGCCGGCCGTACTGCGTCGTGCTGCTGGATGAGATCGAGAAGGCGCATCCCGAGGTCTTCAACATCCTGCTGCAG
GTGCTGGAGGACGGCCGGCTGACCGAGGCCAAGGGCCGCACCGTGGACTTCCGCAACACCGTGATCATCATGACCTCCAA
CGCGGGCGCCCAGGCCATCCAGGGCGACAAGAAGCTGGGCTTCACCGTCCAGGAGGACGAGAAGGAGCGGTACGAGCGGA
TGAAGTCCCGGGTCATGGACGAGGTCAAGCGGCTCTTCCGGCCCGAGTTCCTCAACCGGCTCGACGAGATCATCATCTTC
CACAGCCTGACCAAGGATCACCTGAAGGAGATCGTGCGGCTGGAGGTCAAGAAGGTGGCTGACCGGCTGAAGGAGCAGGG
CGTGGAGCTGACCCTTTCCGACTCCGCCCTGGAGAAGCTGGTCGCGGAAGGTTACGACGAGAAGTTCGGCGCCCGCCCGC
TGCGCCGGGCCATCCAGCGGCTGGTGGAGGACCCGCTCTCCGAGGAGATGCTCCGGCAGCCGTTCAAGTACGGCGAGCAG
GTGTACGTGGACACCGACGCGGAAGGCAAGATCGTCTTCAAGCGCACCGAGCCCTCCGCCGAGTCGGTGGGCGTCGGCAG
CGGCGAGACCACGCAGGCTTAG

Upstream 100 bases:

>100_bases
CACCGCAGGGCGCAGCGGTCCCAATCGGTAAGTGTGCGGCGAGGGCGATGCCTCGCCACGTGGTTCCGGAATAAACAGAT
GGATAGGGGGTAAGTCGCGC

Downstream 100 bases:

>100_bases
CGGCCCCGCTGGCCCGGCCCGTTCAGCAGGCGCCGGTCACCCCGTGCTGGGGGACCGGCGCCTGCCTTGCTTTTTCTGTT
GGAGGATTCAGGTATCGGAC

Product: class III stress response-related ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 833; Mature: 833

Protein sequence:

>833_residues
MFSRYTERAQRVIVLAQDEARRLNYDYVGTEHLLLGLIREGEGIAAKALQSLGIQLEQVRAEVEKMIGKGSASSRGEIGF
TPRAKKVMVELAIEEARLLGHNYVGTEHILLGLIREGEGVAAQVLQNLGADLERVRNQVIHLLGGVPHPPAGSSMPGSAK
VKGPKTSTSTLDQFGRDLNQMARDGKLDPVIGREKEIERVIQILTRRTKNNPVLIGEPGVGKTAIAEGLAQRIVDGRVPE
ILKDKRVVALDLASLVAGSKYRGEFEERLKKVLEEIRNAGNVILFIDELHTIIGAGAAEGAIDASNILKPALARGELQAI
GATTIDEYRKYVEKDAALERRFQPVMVEEPSPEDAIQILKGLRDRYEAHHRVEITDAAIEAAVRLSDRYVTDRFLPDKAV
DLIDEAASRVRLSTFVAPPNLKELEDKLEEVRKEKEAAVQGQEFEKAARLRDKETKLKEELERQKNEWQQKKVTAKCVVN
EEDIATIVSQWTGIPATKLTMDESQRLLNLEKVLHEKVVGQDEAVAAVARAIRRARAGLKDPKRPIGSFIFLGPTGTGKT
HLAKALAEALFGDEDAMVRIDMSEYMERHTTSRLVGAPPGYVGYEEGGQLTEAVRRRPYCVVLLDEIEKAHPEVFNILLQ
VLEDGRLTEAKGRTVDFRNTVIIMTSNAGAQAIQGDKKLGFTVQEDEKERYERMKSRVMDEVKRLFRPEFLNRLDEIIIF
HSLTKDHLKEIVRLEVKKVADRLKEQGVELTLSDSALEKLVAEGYDEKFGARPLRRAIQRLVEDPLSEEMLRQPFKYGEQ
VYVDTDAEGKIVFKRTEPSAESVGVGSGETTQA

Sequences:

>Translated_833_residues
MFSRYTERAQRVIVLAQDEARRLNYDYVGTEHLLLGLIREGEGIAAKALQSLGIQLEQVRAEVEKMIGKGSASSRGEIGF
TPRAKKVMVELAIEEARLLGHNYVGTEHILLGLIREGEGVAAQVLQNLGADLERVRNQVIHLLGGVPHPPAGSSMPGSAK
VKGPKTSTSTLDQFGRDLNQMARDGKLDPVIGREKEIERVIQILTRRTKNNPVLIGEPGVGKTAIAEGLAQRIVDGRVPE
ILKDKRVVALDLASLVAGSKYRGEFEERLKKVLEEIRNAGNVILFIDELHTIIGAGAAEGAIDASNILKPALARGELQAI
GATTIDEYRKYVEKDAALERRFQPVMVEEPSPEDAIQILKGLRDRYEAHHRVEITDAAIEAAVRLSDRYVTDRFLPDKAV
DLIDEAASRVRLSTFVAPPNLKELEDKLEEVRKEKEAAVQGQEFEKAARLRDKETKLKEELERQKNEWQQKKVTAKCVVN
EEDIATIVSQWTGIPATKLTMDESQRLLNLEKVLHEKVVGQDEAVAAVARAIRRARAGLKDPKRPIGSFIFLGPTGTGKT
HLAKALAEALFGDEDAMVRIDMSEYMERHTTSRLVGAPPGYVGYEEGGQLTEAVRRRPYCVVLLDEIEKAHPEVFNILLQ
VLEDGRLTEAKGRTVDFRNTVIIMTSNAGAQAIQGDKKLGFTVQEDEKERYERMKSRVMDEVKRLFRPEFLNRLDEIIIF
HSLTKDHLKEIVRLEVKKVADRLKEQGVELTLSDSALEKLVAEGYDEKFGARPLRRAIQRLVEDPLSEEMLRQPFKYGEQ
VYVDTDAEGKIVFKRTEPSAESVGVGSGETTQA
>Mature_833_residues
MFSRYTERAQRVIVLAQDEARRLNYDYVGTEHLLLGLIREGEGIAAKALQSLGIQLEQVRAEVEKMIGKGSASSRGEIGF
TPRAKKVMVELAIEEARLLGHNYVGTEHILLGLIREGEGVAAQVLQNLGADLERVRNQVIHLLGGVPHPPAGSSMPGSAK
VKGPKTSTSTLDQFGRDLNQMARDGKLDPVIGREKEIERVIQILTRRTKNNPVLIGEPGVGKTAIAEGLAQRIVDGRVPE
ILKDKRVVALDLASLVAGSKYRGEFEERLKKVLEEIRNAGNVILFIDELHTIIGAGAAEGAIDASNILKPALARGELQAI
GATTIDEYRKYVEKDAALERRFQPVMVEEPSPEDAIQILKGLRDRYEAHHRVEITDAAIEAAVRLSDRYVTDRFLPDKAV
DLIDEAASRVRLSTFVAPPNLKELEDKLEEVRKEKEAAVQGQEFEKAARLRDKETKLKEELERQKNEWQQKKVTAKCVVN
EEDIATIVSQWTGIPATKLTMDESQRLLNLEKVLHEKVVGQDEAVAAVARAIRRARAGLKDPKRPIGSFIFLGPTGTGKT
HLAKALAEALFGDEDAMVRIDMSEYMERHTTSRLVGAPPGYVGYEEGGQLTEAVRRRPYCVVLLDEIEKAHPEVFNILLQ
VLEDGRLTEAKGRTVDFRNTVIIMTSNAGAQAIQGDKKLGFTVQEDEKERYERMKSRVMDEVKRLFRPEFLNRLDEIIIF
HSLTKDHLKEIVRLEVKKVADRLKEQGVELTLSDSALEKLVAEGYDEKFGARPLRRAIQRLVEDPLSEEMLRQPFKYGEQ
VYVDTDAEGKIVFKRTEPSAESVGVGSGETTQA

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=298, Percent_Identity=36.241610738255, Blast_Score=198, Evalue=2e-50,
Organism=Escherichia coli, GI1788943, Length=877, Percent_Identity=46.636259977195, Blast_Score=738, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=804, Percent_Identity=40.547263681592, Blast_Score=525, Evalue=1e-150,
Organism=Saccharomyces cerevisiae, GI6320464, Length=696, Percent_Identity=48.9942528735632, Blast_Score=644, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=884, Percent_Identity=36.5384615384615, Blast_Score=528, Evalue=1e-150,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 92882; Mature: 92882

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS50151 UVR ; PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSRYTERAQRVIVLAQDEARRLNYDYVGTEHLLLGLIREGEGIAAKALQSLGIQLEQVR
CCCHHHHHHCEEEEEECCCHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHH
AEVEKMIGKGSASSRGEIGFTPRAKKVMVELAIEEARLLGHNYVGTEHILLGLIREGEGV
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCH
AAQVLQNLGADLERVRNQVIHLLGGVPHPPAGSSMPGSAKVKGPKTSTSTLDQFGRDLNQ
HHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
MARDGKLDPVIGREKEIERVIQILTRRTKNNPVLIGEPGVGKTAIAEGLAQRIVDGRVPE
HHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCHH
ILKDKRVVALDLASLVAGSKYRGEFEERLKKVLEEIRNAGNVILFIDELHTIIGAGAAEG
HHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCC
AIDASNILKPALARGELQAIGATTIDEYRKYVEKDAALERRFQPVMVEEPSPEDAIQILK
CCCHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHH
GLRDRYEAHHRVEITDAAIEAAVRLSDRYVTDRFLPDKAVDLIDEAASRVRLSTFVAPPN
HHHHHHHHHCEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCCC
LKELEDKLEEVRKEKEAAVQGQEFEKAARLRDKETKLKEELERQKNEWQQKKVTAKCVVN
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EEDIATIVSQWTGIPATKLTMDESQRLLNLEKVLHEKVVGQDEAVAAVARAIRRARAGLK
HHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
DPKRPIGSFIFLGPTGTGKTHLAKALAEALFGDEDAMVRIDMSEYMERHTTSRLVGAPPG
CCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHCCCCCC
YVGYEEGGQLTEAVRRRPYCVVLLDEIEKAHPEVFNILLQVLEDGRLTEAKGRTVDFRNT
CCCCCCCCHHHHHHHHCCEEEEEHHHHHHHCHHHHHHHHHHHCCCCEECCCCCEEEECCE
VIIMTSNAGAQAIQGDKKLGFTVQEDEKERYERMKSRVMDEVKRLFRPEFLNRLDEIIIF
EEEEECCCCCHHHCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
HSLTKDHLKEIVRLEVKKVADRLKEQGVELTLSDSALEKLVAEGYDEKFGARPLRRAIQR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHCCCCHHCCCHHHHHHHHH
LVEDPLSEEMLRQPFKYGEQVYVDTDAEGKIVFKRTEPSAESVGVGSGETTQA
HHHCCCHHHHHHHHHHCCCEEEEECCCCCCEEEEECCCCHHHCCCCCCCCCCC
>Mature Secondary Structure
MFSRYTERAQRVIVLAQDEARRLNYDYVGTEHLLLGLIREGEGIAAKALQSLGIQLEQVR
CCCHHHHHHCEEEEEECCCHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHH
AEVEKMIGKGSASSRGEIGFTPRAKKVMVELAIEEARLLGHNYVGTEHILLGLIREGEGV
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCH
AAQVLQNLGADLERVRNQVIHLLGGVPHPPAGSSMPGSAKVKGPKTSTSTLDQFGRDLNQ
HHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
MARDGKLDPVIGREKEIERVIQILTRRTKNNPVLIGEPGVGKTAIAEGLAQRIVDGRVPE
HHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCHH
ILKDKRVVALDLASLVAGSKYRGEFEERLKKVLEEIRNAGNVILFIDELHTIIGAGAAEG
HHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCC
AIDASNILKPALARGELQAIGATTIDEYRKYVEKDAALERRFQPVMVEEPSPEDAIQILK
CCCHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHH
GLRDRYEAHHRVEITDAAIEAAVRLSDRYVTDRFLPDKAVDLIDEAASRVRLSTFVAPPN
HHHHHHHHHCEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCCC
LKELEDKLEEVRKEKEAAVQGQEFEKAARLRDKETKLKEELERQKNEWQQKKVTAKCVVN
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EEDIATIVSQWTGIPATKLTMDESQRLLNLEKVLHEKVVGQDEAVAAVARAIRRARAGLK
HHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
DPKRPIGSFIFLGPTGTGKTHLAKALAEALFGDEDAMVRIDMSEYMERHTTSRLVGAPPG
CCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHCCCCCC
YVGYEEGGQLTEAVRRRPYCVVLLDEIEKAHPEVFNILLQVLEDGRLTEAKGRTVDFRNT
CCCCCCCCHHHHHHHHCCEEEEEHHHHHHHCHHHHHHHHHHHCCCCEECCCCCEEEECCE
VIIMTSNAGAQAIQGDKKLGFTVQEDEKERYERMKSRVMDEVKRLFRPEFLNRLDEIIIF
EEEEECCCCCHHHCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
HSLTKDHLKEIVRLEVKKVADRLKEQGVELTLSDSALEKLVAEGYDEKFGARPLRRAIQR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHCCCCHHCCCHHHHHHHHH
LVEDPLSEEMLRQPFKYGEQVYVDTDAEGKIVFKRTEPSAESVGVGSGETTQA
HHHCCCHHHHHHHHHHCCCEEEEECCCCCCEEEEECCCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]