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The map label for this gene is radA [H]

Identifier: 51894263

GI number: 51894263

Start: 3327414

End: 3328784

Strand: Reverse

Name: radA [H]

Synonym: STH3128

Alternate gene names: 51894263

Gene position: 3328784-3327414 (Counterclockwise)

Preceding gene: 51894264

Following gene: 51894262

Centisome position: 93.34

GC content: 70.97

Gene sequence:

>1371_bases
TTGGCGAAGTCCAGGAGCGCCTTCTTTTGTCAGGAGTGCGGCTACGAGTCGCCGCGGTGGATGGGGCGGTGCCCCGGCTG
CGGTGCCTGGAACACCATGGTGGAGGAGCCCGTGAACCCGCCGGGCGGGCGGGGCCTGCTGACGTCTGACCCGGGCACGG
GCGGGCCGCCGCTGGCGATCGGGGAGGTGGAGACCGAGGACGCGCAGCGGCTGGAGACGGGCATGGACGAGCTGGACCGG
GTGCTGGGCGGCGGCATCGTGCCCGGCTCTTTCGTGCTGGTGGGCGGCGACCCGGGCATCGGCAAGTCGACCCTGCTGCT
GCAGCTGGCGGCCGGCGTGGCCCGGCAGCACGGCACCGTGCTCTATGCCTCCGGCGAGGAGTCCGCCAGGCAGATCCGGA
TGCGAGCCGACCGGTTGGGGACCATCCACCCGCGCCTTCTGGTGCTGGCCGAGACGAACCTGGAGGCCATCGCGCACCAC
GCGGCCCAGGTGGCCCCCCGGCTGCTCATCGTCGACTCCATCCAGACGGTCTTCCGCCCCGACCTGCCTTCCGCCCCCGG
CTCCGTCAGCCAGGTGCGGGAGTGCGCCGCCCAGCTGCTCCGGGTGGCGAAGGGGCAGAACCTCGCCATCTTTATCGTGG
GCCACGTCACCAAAGAGGGCTCCCTGGCCGGCCCGCGGGTACTGGAGCATATCGTGGACACCGTTCTCTACTTCGAGGGC
GACCGGCACGCCAGCTTCCGGATCCTGCGCGCGGTGAAAAACCGCTTCGGCTCCACGAATGAGATTGGCATCTTCGAGAT
GCGGGACGCGGGCCTGGCGCCGGTCGGCAACGCCTCCCAGCTGTTCCTGGCGGAGCGGCCGGTGGAGGTGGCGGGCTCCG
TGGTCATGCCGGCGATGGAGGGCACCCGGCCGCTCCTGGTGGAGGTGCAGGCGCTGGTGAGCGCGTCCACCTTCGTGACG
CCGCGGCGGACCGCGGAGGGCATCGACCTGAACCGGCTGCAGCTGATCATCGCGGTGCTGGAGAAGCGGGTGGGACTGCT
GCTGGGCAACCATGACGCCTACGTCAAGGTGGCGGGCGGGGTGCGGCTGGCGGAGCCCGCGATCGACCTGGCCCTGGCGG
TGGCCCTGGCCTCCAGCTTCCGGGACCAGCCTCCCGACCCGCGTACGGTGGTCGTGGGCGAGGTCGGGCTGGCCGGCGAG
GTGCGGGCGGTGTCCCGCATCGACCAGCGCATTCGCGAGGCCGAGAAGATGGGTTTCGACCGCATGGTATTGCCACGGGC
GAACCTCCGTAGCCTAAGCATGAAGACCGACGTGGAACTGGTCGGCGTGGAGACGGTGATGGAAGGACTCGAGGCGGCCC
TCGGCCGCTGA

Upstream 100 bases:

>100_bases
CCTGCCGCGCGCATCCGGGGCGCCGGCGCGCCGCGTGCAGGAGGGGGCGGGCCTCGCCCCGAAACAAGACCGGACCGAGG
ACGACGGGGAGGCAGTGGCG

Downstream 100 bases:

>100_bases
GCCGCGCGCAGGGGGTGCGGGGATGGAGGACCGAAGCGGCTTCTGGCAGGTGCTGCAGCAACTCGCCCCCGGCACCGCGC
TGCGGGAGGGGCTGGAGTCC

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog [H]

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MAKSRSAFFCQECGYESPRWMGRCPGCGAWNTMVEEPVNPPGGRGLLTSDPGTGGPPLAIGEVETEDAQRLETGMDELDR
VLGGGIVPGSFVLVGGDPGIGKSTLLLQLAAGVARQHGTVLYASGEESARQIRMRADRLGTIHPRLLVLAETNLEAIAHH
AAQVAPRLLIVDSIQTVFRPDLPSAPGSVSQVRECAAQLLRVAKGQNLAIFIVGHVTKEGSLAGPRVLEHIVDTVLYFEG
DRHASFRILRAVKNRFGSTNEIGIFEMRDAGLAPVGNASQLFLAERPVEVAGSVVMPAMEGTRPLLVEVQALVSASTFVT
PRRTAEGIDLNRLQLIIAVLEKRVGLLLGNHDAYVKVAGGVRLAEPAIDLALAVALASSFRDQPPDPRTVVVGEVGLAGE
VRAVSRIDQRIREAEKMGFDRMVLPRANLRSLSMKTDVELVGVETVMEGLEAALGR

Sequences:

>Translated_456_residues
MAKSRSAFFCQECGYESPRWMGRCPGCGAWNTMVEEPVNPPGGRGLLTSDPGTGGPPLAIGEVETEDAQRLETGMDELDR
VLGGGIVPGSFVLVGGDPGIGKSTLLLQLAAGVARQHGTVLYASGEESARQIRMRADRLGTIHPRLLVLAETNLEAIAHH
AAQVAPRLLIVDSIQTVFRPDLPSAPGSVSQVRECAAQLLRVAKGQNLAIFIVGHVTKEGSLAGPRVLEHIVDTVLYFEG
DRHASFRILRAVKNRFGSTNEIGIFEMRDAGLAPVGNASQLFLAERPVEVAGSVVMPAMEGTRPLLVEVQALVSASTFVT
PRRTAEGIDLNRLQLIIAVLEKRVGLLLGNHDAYVKVAGGVRLAEPAIDLALAVALASSFRDQPPDPRTVVVGEVGLAGE
VRAVSRIDQRIREAEKMGFDRMVLPRANLRSLSMKTDVELVGVETVMEGLEAALGR
>Mature_455_residues
AKSRSAFFCQECGYESPRWMGRCPGCGAWNTMVEEPVNPPGGRGLLTSDPGTGGPPLAIGEVETEDAQRLETGMDELDRV
LGGGIVPGSFVLVGGDPGIGKSTLLLQLAAGVARQHGTVLYASGEESARQIRMRADRLGTIHPRLLVLAETNLEAIAHHA
AQVAPRLLIVDSIQTVFRPDLPSAPGSVSQVRECAAQLLRVAKGQNLAIFIVGHVTKEGSLAGPRVLEHIVDTVLYFEGD
RHASFRILRAVKNRFGSTNEIGIFEMRDAGLAPVGNASQLFLAERPVEVAGSVVMPAMEGTRPLLVEVQALVSASTFVTP
RRTAEGIDLNRLQLIIAVLEKRVGLLLGNHDAYVKVAGGVRLAEPAIDLALAVALASSFRDQPPDPRTVVVGEVGLAGEV
RAVSRIDQRIREAEKMGFDRMVLPRANLRSLSMKTDVELVGVETVMEGLEAALGR

Specific function: May play a role in the repair of endogenous alkylation damage [H]

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=435, Percent_Identity=48.735632183908, Blast_Score=395, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568 [H]

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C [H]

EC number: NA

Molecular weight: Translated: 48680; Mature: 48549

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS50162 RECA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSRSAFFCQECGYESPRWMGRCPGCGAWNTMVEEPVNPPGGRGLLTSDPGTGGPPLAI
CCCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCEEEECCCCCCCCCEEE
GEVETEDAQRLETGMDELDRVLGGGIVPGSFVLVGGDPGIGKSTLLLQLAAGVARQHGTV
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCEE
LYASGEESARQIRMRADRLGTIHPRLLVLAETNLEAIAHHAAQVAPRLLIVDSIQTVFRP
EEECCCHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHCCCEEEHHHHHHHHCC
DLPSAPGSVSQVRECAAQLLRVAKGQNLAIFIVGHVTKEGSLAGPRVLEHIVDTVLYFEG
CCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHCCC
DRHASFRILRAVKNRFGSTNEIGIFEMRDAGLAPVGNASQLFLAERPVEVAGSVVMPAME
CCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCHHHHCCEEECCCC
GTRPLLVEVQALVSASTFVTPRRTAEGIDLNRLQLIIAVLEKRVGLLLGNHDAYVKVAGG
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEECCCCCEEEEECC
VRLAEPAIDLALAVALASSFRDQPPDPRTVVVGEVGLAGEVRAVSRIDQRIREAEKMGFD
CEECHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCC
RMVLPRANLRSLSMKTDVELVGVETVMEGLEAALGR
EEECCCCCCHHCCCCCCEEEEEHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKSRSAFFCQECGYESPRWMGRCPGCGAWNTMVEEPVNPPGGRGLLTSDPGTGGPPLAI
CCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCEEEECCCCCCCCCEEE
GEVETEDAQRLETGMDELDRVLGGGIVPGSFVLVGGDPGIGKSTLLLQLAAGVARQHGTV
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCEE
LYASGEESARQIRMRADRLGTIHPRLLVLAETNLEAIAHHAAQVAPRLLIVDSIQTVFRP
EEECCCHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHCCCEEEHHHHHHHHCC
DLPSAPGSVSQVRECAAQLLRVAKGQNLAIFIVGHVTKEGSLAGPRVLEHIVDTVLYFEG
CCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHCCC
DRHASFRILRAVKNRFGSTNEIGIFEMRDAGLAPVGNASQLFLAERPVEVAGSVVMPAME
CCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCHHHHCCEEECCCC
GTRPLLVEVQALVSASTFVTPRRTAEGIDLNRLQLIIAVLEKRVGLLLGNHDAYVKVAGG
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEECCCCCEEEEECC
VRLAEPAIDLALAVALASSFRDQPPDPRTVVVGEVGLAGEVRAVSRIDQRIREAEKMGFD
CEECHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCC
RMVLPRANLRSLSMKTDVELVGVETVMEGLEAALGR
EEECCCCCCHHCCCCCCEEEEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 8016066 [H]