Click here to switch to the map view.

The map label for this gene is yacO [H]

Identifier: 51894250

GI number: 51894250

Start: 3315558

End: 3316298

Strand: Reverse

Name: yacO [H]

Synonym: STH3115

Alternate gene names: 51894250

Gene position: 3316298-3315558 (Counterclockwise)

Preceding gene: 51894251

Following gene: 51894249

Centisome position: 92.99

GC content: 72.2

Gene sequence:

>741_bases
GTGTCTGGACAGATCGAAGGACGGAACCCCGTGCTGGAGGCGCTCCGGTCGGGGCGGACCATCAACCGGATCCTGGTGGC
AAAGGGAGCCCGGGAGGGCTCGATCCGGGAGGTCATCGCCCTGGCCCGGAGCCAGGGGGTCATCGTGCAGGAGGTGGCCC
GGGAGCGGCTGGACGCGATGGCCCGCGGCCGGAATCACCAGGGGGTCATCGCGCTGGCCGCCGCACACCGGTACTACGAC
CTGGACGAGGTGCTGGAGCGGGCGGCGGCCTCGGGGGAGGACGGGCTTCTCCTGGTGCTGGACGGCATCGAGGACCCGCA
GAACCTGGGCTCGCTGTTGCGCACGGCGGACGCGGCCGGCGTGCACGGCGTGATCATCCCTGAGCGGCGGGCCGTCGGGC
TCACGGAGACGGTGGCCAAGGTGTCGGCCGGAGCGGTGGAGTACGTGCCGGTCGCCCGCGTCACCAACATCGCCCGCACC
CTGGAGATGCTGAAGGAGCGAGGGTACTGGGTCGTGGGCACGCACCAGGAGGCCGACGAACTCTACTACGAGGCGCGCCT
CACCGGACCGCTCGCGGTGGTCATCGGCAGCGAGGGCCGGGGGATGAGCCGGCTGGTCGCGGAGACCTGCGACTTCACGG
TCCGGCTCCCCATGCGGGGCCACGTGACGTCGCTGAACGCCGCCGTGGCCGGGGCGATCCTGCTTTACGAGGTGCGCCGC
CAGCGCAGCGCGGGGGCCTGA

Upstream 100 bases:

>100_bases
GACGAGGAGAACCCGTACGATTTCGTCGTCGAGCACTACCGCCGGCGGCGCATTCCCGCCGGCGGGGCCGGGCAGACTGA
ACCCGAAGGAGACTGAGCTC

Downstream 100 bases:

>100_bases
GGAAGAGGGGGAGGGGCCATCCGCTTCAACGCGAAGCCGGGCCGCCGGTCTGTGGCGGCCCTGTTGCTTATCACGGCCTT
GTGGATCGCCTGCCTGGCGC

Product: rRNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MSGQIEGRNPVLEALRSGRTINRILVAKGAREGSIREVIALARSQGVIVQEVARERLDAMARGRNHQGVIALAAAHRYYD
LDEVLERAAASGEDGLLLVLDGIEDPQNLGSLLRTADAAGVHGVIIPERRAVGLTETVAKVSAGAVEYVPVARVTNIART
LEMLKERGYWVVGTHQEADELYYEARLTGPLAVVIGSEGRGMSRLVAETCDFTVRLPMRGHVTSLNAAVAGAILLYEVRR
QRSAGA

Sequences:

>Translated_246_residues
MSGQIEGRNPVLEALRSGRTINRILVAKGAREGSIREVIALARSQGVIVQEVARERLDAMARGRNHQGVIALAAAHRYYD
LDEVLERAAASGEDGLLLVLDGIEDPQNLGSLLRTADAAGVHGVIIPERRAVGLTETVAKVSAGAVEYVPVARVTNIART
LEMLKERGYWVVGTHQEADELYYEARLTGPLAVVIGSEGRGMSRLVAETCDFTVRLPMRGHVTSLNAAVAGAILLYEVRR
QRSAGA
>Mature_245_residues
SGQIEGRNPVLEALRSGRTINRILVAKGAREGSIREVIALARSQGVIVQEVARERLDAMARGRNHQGVIALAAAHRYYDL
DEVLERAAASGEDGLLLVLDGIEDPQNLGSLLRTADAAGVHGVIIPERRAVGLTETVAKVSAGAVEYVPVARVTNIARTL
EMLKERGYWVVGTHQEADELYYEARLTGPLAVVIGSEGRGMSRLVAETCDFTVRLPMRGHVTSLNAAVAGAILLYEVRRQ
RSAGA

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=254, Percent_Identity=32.6771653543307, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI110825988, Length=179, Percent_Identity=29.0502793296089, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1790623, Length=244, Percent_Identity=45.0819672131148, Blast_Score=201, Evalue=3e-53,
Organism=Escherichia coli, GI1790083, Length=169, Percent_Identity=31.9526627218935, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1788935, Length=186, Percent_Identity=27.9569892473118, Blast_Score=71, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17555908, Length=259, Percent_Identity=25.8687258687259, Blast_Score=80, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6324775, Length=162, Percent_Identity=30.8641975308642, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 26455; Mature: 26324

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGQIEGRNPVLEALRSGRTINRILVAKGAREGSIREVIALARSQGVIVQEVARERLDAM
CCCCCCCCCHHHHHHHCCCCEEEHEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
ARGRNHQGVIALAAAHRYYDLDEVLERAAASGEDGLLLVLDGIEDPQNLGSLLRTADAAG
HCCCCCCCEEEEEEHHHCCCHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCCC
VHGVIIPERRAVGLTETVAKVSAGAVEYVPVARVTNIARTLEMLKERGYWVVGTHQEADE
CCEEEECCCCCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEECCCHHHH
LYYEARLTGPLAVVIGSEGRGMSRLVAETCDFTVRLPMRGHVTSLNAAVAGAILLYEVRR
HHHHEECCCCEEEEECCCCCCHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHH
QRSAGA
HHCCCC
>Mature Secondary Structure 
SGQIEGRNPVLEALRSGRTINRILVAKGAREGSIREVIALARSQGVIVQEVARERLDAM
CCCCCCCCHHHHHHHCCCCEEEHEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
ARGRNHQGVIALAAAHRYYDLDEVLERAAASGEDGLLLVLDGIEDPQNLGSLLRTADAAG
HCCCCCCCEEEEEEHHHCCCHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCCC
VHGVIIPERRAVGLTETVAKVSAGAVEYVPVARVTNIARTLEMLKERGYWVVGTHQEADE
CCEEEECCCCCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEECCCHHHH
LYYEARLTGPLAVVIGSEGRGMSRLVAETCDFTVRLPMRGHVTSLNAAVAGAILLYEVRR
HHHHEECCCCEEEEECCCCCCHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHH
QRSAGA
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]