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The map label for this gene is secY [H]

Identifier: 51894190

GI number: 51894190

Start: 3264835

End: 3266103

Strand: Reverse

Name: secY [H]

Synonym: STH3055

Alternate gene names: 51894190

Gene position: 3266103-3264835 (Counterclockwise)

Preceding gene: 51894191

Following gene: 51894189

Centisome position: 91.59

GC content: 62.1

Gene sequence:

>1269_bases
ATGCTGGAAACGCTGCGCAATTCGATGCGCGTGCCCGGGCTGAGGAAGCGTCTGCTCTTCACCATCGGGATGCTCGTCGT
CATTCGAATTTGCGCGCACATTCCCGTCCCTGGGGTCAACCTGGATCGGTTGACGGAAGTGTTCGGAGCAGGCGGCCTCT
TCGATTTCTTCGACATCTTCGCCGGAGGCGCGTTCTCCCAGTTTGCCATCGTCGCGATGGGCGTGACCCCCTACATCAAC
TCCTCCATTATCATGCAGCTGCTCACGGTCGTGATCCCGCGGCTGGAGGAGCTGCAGAAGGAGGGCGAGGAGGGGCGCAA
GAAGATCCAGCAGTACACCCGCTACGGCGCGGTGGTGCTGGGTCTCGTCCAGGCCTTTGGCATCGGCTACGCGCTGCGGA
GCTACGGCGCCTTCTACAGCAACAGCTGGACGACCCTCTTCGTGATCATGGTCAGCCTGACCGCCGGCACCGCCCTGGTG
ATGTGGATCGGCGAGGAGATCACGGAGAAGGGCATCGGCAACGGCATTTCGCTGATCATCTTCGCGAACATCGTCTCCCG
GCTGCCTTACTCCATCTACAACGAGATCCTGTTGCTCCGGGCCGGCCAGCGTAACATCTTCCAGCCTCTGCTCGTGGCTG
TGGTCGCCCTCTTGATGGTGGTCTTCGTGGTCATCATCAACGAAGCCGTGCGGAAGATCCCGGTGGAGTACGCGAAGCGC
GTTGTCGGCAGGCGGGTGGTCGGCGGACAGCGGACTCACCTGCCCATCCGCATCAACCAGGCCGGCGTGATTCCGCTGAT
CTTCGCCTCGTCCCTGATGTACTTCCCCATCACGATCGCGGGGTTCTTCCCGAACTCTGACTTCGCGGTCTTCGTGGGCA
GGTACCTGGATACGCGGTCCTGGTGGTTCATGCTGATCAACGCGCTGCTGATCGTCTTCTTCACCTACTTCTACACCGCG
ATCACCTTCAACCCTGAGAACGTGGCCGACAACATCAAGAAGAACGGCGGGTTCATTCCGGGGTATCGGCCGGGCCGGCC
CACCGCCGAGTACCTGGAGCGGGTCTCCAGCCGGCTCACGCTGGTGGGTGGCCTGTTCCTGGCGGCGGTGACGATCCTGC
CGATCACGATCATGAGCCTCGCCGGCGTCCAGAATGCGTACATCGGCGGCTCCTCGCTGCTGATCGTGGTCAGTGTGGCG
CTGGAGACGACGAAGCAGCTGGAGGCGCAACTGGTGATGCGGCACTACCAGGGGTTCATGCGGACTTAG

Upstream 100 bases:

>100_bases
ACGCGGTAAGCGAGTCTGCCCGGCAGAAGATTGAGGCCGCAGGCGGAAAGGTTGAGGTTATCGGAGAAGCCACCGAAGAG
GTGAAGTAACAGCCATGGCG

Downstream 100 bases:

>100_bases
GTGATACACGAGGGTGCGCAGAGGACCGGACCGTCCTCCCCGTCCGGAGGACGCCGGTCCTCGCGGGTCCCGTCTGCGCG
CCCGGTTTGGTGAAAGCGAG

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MLETLRNSMRVPGLRKRLLFTIGMLVVIRICAHIPVPGVNLDRLTEVFGAGGLFDFFDIFAGGAFSQFAIVAMGVTPYIN
SSIIMQLLTVVIPRLEELQKEGEEGRKKIQQYTRYGAVVLGLVQAFGIGYALRSYGAFYSNSWTTLFVIMVSLTAGTALV
MWIGEEITEKGIGNGISLIIFANIVSRLPYSIYNEILLLRAGQRNIFQPLLVAVVALLMVVFVVIINEAVRKIPVEYAKR
VVGRRVVGGQRTHLPIRINQAGVIPLIFASSLMYFPITIAGFFPNSDFAVFVGRYLDTRSWWFMLINALLIVFFTYFYTA
ITFNPENVADNIKKNGGFIPGYRPGRPTAEYLERVSSRLTLVGGLFLAAVTILPITIMSLAGVQNAYIGGSSLLIVVSVA
LETTKQLEAQLVMRHYQGFMRT

Sequences:

>Translated_422_residues
MLETLRNSMRVPGLRKRLLFTIGMLVVIRICAHIPVPGVNLDRLTEVFGAGGLFDFFDIFAGGAFSQFAIVAMGVTPYIN
SSIIMQLLTVVIPRLEELQKEGEEGRKKIQQYTRYGAVVLGLVQAFGIGYALRSYGAFYSNSWTTLFVIMVSLTAGTALV
MWIGEEITEKGIGNGISLIIFANIVSRLPYSIYNEILLLRAGQRNIFQPLLVAVVALLMVVFVVIINEAVRKIPVEYAKR
VVGRRVVGGQRTHLPIRINQAGVIPLIFASSLMYFPITIAGFFPNSDFAVFVGRYLDTRSWWFMLINALLIVFFTYFYTA
ITFNPENVADNIKKNGGFIPGYRPGRPTAEYLERVSSRLTLVGGLFLAAVTILPITIMSLAGVQNAYIGGSSLLIVVSVA
LETTKQLEAQLVMRHYQGFMRT
>Mature_422_residues
MLETLRNSMRVPGLRKRLLFTIGMLVVIRICAHIPVPGVNLDRLTEVFGAGGLFDFFDIFAGGAFSQFAIVAMGVTPYIN
SSIIMQLLTVVIPRLEELQKEGEEGRKKIQQYTRYGAVVLGLVQAFGIGYALRSYGAFYSNSWTTLFVIMVSLTAGTALV
MWIGEEITEKGIGNGISLIIFANIVSRLPYSIYNEILLLRAGQRNIFQPLLVAVVALLMVVFVVIINEAVRKIPVEYAKR
VVGRRVVGGQRTHLPIRINQAGVIPLIFASSLMYFPITIAGFFPNSDFAVFVGRYLDTRSWWFMLINALLIVFFTYFYTA
ITFNPENVADNIKKNGGFIPGYRPGRPTAEYLERVSSRLTLVGGLFLAAVTILPITIMSLAGVQNAYIGGSSLLIVVSVA
LETTKQLEAQLVMRHYQGFMRT

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=417, Percent_Identity=44.8441247002398, Blast_Score=304, Evalue=9e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 46808; Mature: 46808

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CC
>Mature Secondary Structure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CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1512566; 10192928; 11058132 [H]