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The map label for this gene is yvoF [H]

Identifier: 51894056

GI number: 51894056

Start: 3148841

End: 3149338

Strand: Reverse

Name: yvoF [H]

Synonym: STH2920

Alternate gene names: 51894056

Gene position: 3149338-3148841 (Counterclockwise)

Preceding gene: 51894057

Following gene: 51894055

Centisome position: 88.31

GC content: 67.47

Gene sequence:

>498_bases
GTGACGCGCCGGCACGAGAGGCTCACCCGGCTGCCCGACTACGGGCCGCACAACCCGCTGCAGTACTGGTACCGGCATGT
CCACCCGCTTCGGGTGGTCTGGAACTTCATCTGTATCTACCTCGCCAGGTACTGCCCCTCGCTCACGCTCAAATGCTGGC
TTTACCGGCTGACCGGGGCGCAGATCGGGCGCAACGTCTCCATCGGCCTGGCGGTCGTGTTCGACATCTTCTACCCCCAC
CTCATCCGCATCGACGACAACAGCGTCGTGGGCTACAACTCGGTGATCCTCTGCCACGACTTCCGGGTGCGGGAGGCGTT
CATCGGGCCGGTCCACATCGGGCGCGACGTGCTGGTGGGGGCCAACTGCACCATCCTGCCCGGGGTCCGCATCGGCGACG
GCGCCGCCGTCTCCGCCATGAGCCTGGTAAACCGGGACATCCCGCCGGGAGCCATGGCCGGCGGGGTGCCGGCGACGGTG
ATCAGCGCCGCACAGTAA

Upstream 100 bases:

>100_bases
CCGGCTACTACCTCTGGCGGGCCGGCGTCCGCCACGACCTGGACCTGAACGCCGTGCCCGGGCTGGGGCTCGGCATCGGC
GGCTGAGGGGGGATGGCGCC

Downstream 100 bases:

>100_bases
TCGCGGACGCCCCGGACCCATAGAATGACAGGACAGGTGGAAGGGGTGGGTGACATGTCGGGCGTGGAGATCCTGCAGGC
GATCCAGACCATCCAGTCCC

Product: acetyltransferase

Products: CoA; aacetyl-beta-D-galactoside [C]

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MTRRHERLTRLPDYGPHNPLQYWYRHVHPLRVVWNFICIYLARYCPSLTLKCWLYRLTGAQIGRNVSIGLAVVFDIFYPH
LIRIDDNSVVGYNSVILCHDFRVREAFIGPVHIGRDVLVGANCTILPGVRIGDGAAVSAMSLVNRDIPPGAMAGGVPATV
ISAAQ

Sequences:

>Translated_165_residues
MTRRHERLTRLPDYGPHNPLQYWYRHVHPLRVVWNFICIYLARYCPSLTLKCWLYRLTGAQIGRNVSIGLAVVFDIFYPH
LIRIDDNSVVGYNSVILCHDFRVREAFIGPVHIGRDVLVGANCTILPGVRIGDGAAVSAMSLVNRDIPPGAMAGGVPATV
ISAAQ
>Mature_164_residues
TRRHERLTRLPDYGPHNPLQYWYRHVHPLRVVWNFICIYLARYCPSLTLKCWLYRLTGAQIGRNVSIGLAVVFDIFYPHL
IRIDDNSVVGYNSVILCHDFRVREAFIGPVHIGRDVLVGANCTILPGVRIGDGAAVSAMSLVNRDIPPGAMAGGVPATVI
SAAQ

Specific function: May Assist Cellular Detoxification By Acetylating Nonmetabolizable Pyranosides, Thereby Preventing Their Reentry Into The Cell. [C]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786537, Length=155, Percent_Identity=31.6129032258064, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011004 [H]

Pfam domain/function: NA

EC number: 2.3.1.18 [C]

Molecular weight: Translated: 18394; Mature: 18263

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRHERLTRLPDYGPHNPLQYWYRHVHPLRVVWNFICIYLARYCPSLTLKCWLYRLTGA
CCCHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
QIGRNVSIGLAVVFDIFYPHLIRIDDNSVVGYNSVILCHDFRVREAFIGPVHIGRDVLVG
HCCCCCHHHHHHHHHHHCCEEEEECCCCEECCCCEEEEECCCHHHHHCCCEECCCEEEEC
ANCTILPGVRIGDGAAVSAMSLVNRDIPPGAMAGGVPATVISAAQ
CCCEEECCCEECCCHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCC
>Mature Secondary Structure 
TRRHERLTRLPDYGPHNPLQYWYRHVHPLRVVWNFICIYLARYCPSLTLKCWLYRLTGA
CCHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
QIGRNVSIGLAVVFDIFYPHLIRIDDNSVVGYNSVILCHDFRVREAFIGPVHIGRDVLVG
HCCCCCHHHHHHHHHHHCCEEEEECCCCEECCCCEEEEECCCHHHHHCCCEECCCEEEEC
ANCTILPGVRIGDGAAVSAMSLVNRDIPPGAMAGGVPATVISAAQ
CCCEEECCCEECCCHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: MgSO4; Mn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 1500 {isopropyl} 1200 {isopropyl} 770 {isopropyl} 360 {isopropyl} 0.18 {acetyl-CoA}} 0.049 {acetyl-CoA}} 0.045 {acetyl-CoA}} 0.04 {acetyl-CoA}} [C]

Substrates: Acetyl-CoA; a beta-D-galactoside [C]

Specific reaction: Acetyl-CoA + a beta-D-galactoside = CoA + aacetyl-beta-D-galactoside [C]

General reaction: Acyl group transfer [C]

Inhibitor: 1, 10-Phenanthroline; Acetyl-CoA; Co2+; CoA; Cu2+; MgSO4; Mn2+; p-Chloromercuribenzoate; Zn2+ [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]