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The map label for this gene is murA2

Identifier: 51894051

GI number: 51894051

Start: 3142767

End: 3144038

Strand: Reverse

Name: murA2

Synonym: STH2915

Alternate gene names: 51894051

Gene position: 3144038-3142767 (Counterclockwise)

Preceding gene: 51894052

Following gene: 51894050

Centisome position: 88.16

GC content: 69.97

Gene sequence:

>1272_bases
TTGACAGCGAAGTTCGTCGTCCGCGGCGGCAACCGCCTCTCCGGCACCGTCACCATCGGCGGCGCCAAGAACAGCGCCTT
GCCCATCGTCACGGCCGCTGCGCTGGCCGCCGAGGGCGAGTCTATTCTGGAGAACGTACCGGATAACTCCGATATACAAC
ACCTCTGTGAGATATTGAGGGCGCTGGGGTGCCGCGTCGAGCGGGTGGCCGAGACCACCCTGCGCATCCAGGCCCGTGAA
CTGGAGCACCACGTCGCACCGTATCACCTGGCCCGCCGTCTGCGGGGCTCCACCTATGTGATGGGGCTCCTGCTCGCGCG
CCTGGGCAAGGGCGAGGTGGCCTGCCCCGGCGGCTGCGAGATCGGGGCCCGTCCGGTGGACTTCCACCTGAAGGGCTTCC
GGGCGCTGGGGGCGGAGGTCGTCGTGGAGCACGGCGCGATGGTCAGCCGGAGGGTGGACCTGCGGGGCGGCCGCTTTTAC
GTGGATCGGGCCAGCGTGGGCACGACGGTGAACATGATCATCACCGCCAGCCTGGCGCCGGGCGTCACGGTGCTGGAGAA
CGCGGCCTGCGAGCCGGAGATCGTCGACTTGGCCAACTTCATCAACGCGATGGGCGGCCGGGTCCGGGGCGCCGGCACCA
ACACGGTGCGCATCGAGGGGGTCGACCGGCTGCGAGGGGCCCGCCACGAGATCATCCCCGACCGGATCGAGGCCGGCACC
TACATGATGATGACCGCCGCCGCCGGAGGCGACGTCGTGGTGGAGAACGTCATCCCCGAGCACCTGGGCACGGTGATCGC
CAAGCTGGTGGAGGCCGGCCAGGAGGTGGAGGAGCACGGCGACTGCATCCGGGTGCGGGCGCGCCCCATCCGGGCGGTGG
ACGTGGAGACCCAGGTCTACCCGGGCTTTCCCACGGACCTGCAGTCGCCCTGGGTCGCCCTCATGGGCCTGGCCGACGGC
ATCTCGGTGGTGCACGAGACGATCTTCGAGAACCGGTTCGGCTTCACCAACGAGCTGATCCGCATGGGGGCGAAGATCAA
GGTGGACCGGAACACCGGGATCATCCGGGGCGTGAAGCGCTACACCGGCGCGCCCGTGGAGGCCAGGGACATCCGGGGCG
GCGCCGCCCTGGTCACCGCGGCCCTGGCGGCGGAGGGCGTCACCGAGGTGTCCGGGGTGCAGTACATCGACCGGGGCTAC
ACCCGCATGGAGGAGAAGCTGGCCGCGCTGGGCGCCGACATCCGGCGGGTACCCAACGGCAGTGAGCAGTGA

Upstream 100 bases:

>100_bases
CGGGGGTTCGGCTTTCTGTTAAAGTGACTAGGTGTGACCGGGTGAGCGTCCAATCAGCGCATACTAGTATGCAACCCGCA
TCGTATGGGGGAGACCGCTA

Downstream 100 bases:

>100_bases
GCGCTGGGTCGGCAGGCGCGAACCAAGCCCCATGCCGGGCCGGCGGGCGGTAAGTTGGGCGGACGCAGCAGGGAACGGAA
GCTTCCCGCCTAATTTATGT

Product: UDP-N-acetylglucosamine enolpyruvyl transferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 2; UDP-N-acetylglucosamine enolpyruvyl transferase 2; EPT 2

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MTAKFVVRGGNRLSGTVTIGGAKNSALPIVTAAALAAEGESILENVPDNSDIQHLCEILRALGCRVERVAETTLRIQARE
LEHHVAPYHLARRLRGSTYVMGLLLARLGKGEVACPGGCEIGARPVDFHLKGFRALGAEVVVEHGAMVSRRVDLRGGRFY
VDRASVGTTVNMIITASLAPGVTVLENAACEPEIVDLANFINAMGGRVRGAGTNTVRIEGVDRLRGARHEIIPDRIEAGT
YMMMTAAAGGDVVVENVIPEHLGTVIAKLVEAGQEVEEHGDCIRVRARPIRAVDVETQVYPGFPTDLQSPWVALMGLADG
ISVVHETIFENRFGFTNELIRMGAKIKVDRNTGIIRGVKRYTGAPVEARDIRGGAALVTAALAAEGVTEVSGVQYIDRGY
TRMEEKLAALGADIRRVPNGSEQ

Sequences:

>Translated_423_residues
MTAKFVVRGGNRLSGTVTIGGAKNSALPIVTAAALAAEGESILENVPDNSDIQHLCEILRALGCRVERVAETTLRIQARE
LEHHVAPYHLARRLRGSTYVMGLLLARLGKGEVACPGGCEIGARPVDFHLKGFRALGAEVVVEHGAMVSRRVDLRGGRFY
VDRASVGTTVNMIITASLAPGVTVLENAACEPEIVDLANFINAMGGRVRGAGTNTVRIEGVDRLRGARHEIIPDRIEAGT
YMMMTAAAGGDVVVENVIPEHLGTVIAKLVEAGQEVEEHGDCIRVRARPIRAVDVETQVYPGFPTDLQSPWVALMGLADG
ISVVHETIFENRFGFTNELIRMGAKIKVDRNTGIIRGVKRYTGAPVEARDIRGGAALVTAALAAEGVTEVSGVQYIDRGY
TRMEEKLAALGADIRRVPNGSEQ
>Mature_422_residues
TAKFVVRGGNRLSGTVTIGGAKNSALPIVTAAALAAEGESILENVPDNSDIQHLCEILRALGCRVERVAETTLRIQAREL
EHHVAPYHLARRLRGSTYVMGLLLARLGKGEVACPGGCEIGARPVDFHLKGFRALGAEVVVEHGAMVSRRVDLRGGRFYV
DRASVGTTVNMIITASLAPGVTVLENAACEPEIVDLANFINAMGGRVRGAGTNTVRIEGVDRLRGARHEIIPDRIEAGTY
MMMTAAAGGDVVVENVIPEHLGTVIAKLVEAGQEVEEHGDCIRVRARPIRAVDVETQVYPGFPTDLQSPWVALMGLADGI
SVVHETIFENRFGFTNELIRMGAKIKVDRNTGIIRGVKRYTGAPVEARDIRGGAALVTAALAAEGVTEVSGVQYIDRGYT
RMEEKLAALGADIRRVPNGSEQ

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=419, Percent_Identity=45.8233890214797, Blast_Score=347, Evalue=7e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA2_SYMTH (Q67KA0)

Other databases:

- EMBL:   AP006840
- RefSeq:   YP_076742.1
- ProteinModelPortal:   Q67KA0
- SMR:   Q67KA0
- GeneID:   2979224
- GenomeReviews:   AP006840_GR
- KEGG:   sth:STH2915
- NMPDR:   fig|292459.1.peg.2789
- HOGENOM:   HBG482701
- OMA:   ENIPEIT
- BioCyc:   STHE292459:STH2915-MONOMER
- BRENDA:   2.5.1.7
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 45281; Mature: 45150

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: ACT_SITE 119-119

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAKFVVRGGNRLSGTVTIGGAKNSALPIVTAAALAAEGESILENVPDNSDIQHLCEILR
CCCEEEEECCCEEEEEEEECCCCCCCCHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHH
ALGCRVERVAETTLRIQARELEHHVAPYHLARRLRGSTYVMGLLLARLGKGEVACPGGCE
HHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHCCCCCEECCCCCC
IGARPVDFHLKGFRALGAEVVVEHGAMVSRRVDLRGGRFYVDRASVGTTVNMIITASLAP
CCCCCEEHHHHHHHHHHHHHHHHCCCHHHEEEECCCCEEEEECCCCCCEEEEEEEECCCC
GVTVLENAACEPEIVDLANFINAMGGRVRGAGTNTVRIEGVDRLRGARHEIIPDRIEAGT
CHHHHHCCCCCCHHHHHHHHHHHHCCCEECCCCCEEEEECHHHHCCCHHHCCCHHHCCCC
YMMMTAAAGGDVVVENVIPEHLGTVIAKLVEAGQEVEEHGDCIRVRARPIRAVDVETQVY
EEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCEEC
PGFPTDLQSPWVALMGLADGISVVHETIFENRFGFTNELIRMGAKIKVDRNTGIIRGVKR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEECCCCHHHHHHH
YTGAPVEARDIRGGAALVTAALAAEGVTEVSGVQYIDRGYTRMEEKLAALGADIRRVPNG
HCCCCCCHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCC
SEQ
CCC
>Mature Secondary Structure 
TAKFVVRGGNRLSGTVTIGGAKNSALPIVTAAALAAEGESILENVPDNSDIQHLCEILR
CCEEEEECCCEEEEEEEECCCCCCCCHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHH
ALGCRVERVAETTLRIQARELEHHVAPYHLARRLRGSTYVMGLLLARLGKGEVACPGGCE
HHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHCCCCCEECCCCCC
IGARPVDFHLKGFRALGAEVVVEHGAMVSRRVDLRGGRFYVDRASVGTTVNMIITASLAP
CCCCCEEHHHHHHHHHHHHHHHHCCCHHHEEEECCCCEEEEECCCCCCEEEEEEEECCCC
GVTVLENAACEPEIVDLANFINAMGGRVRGAGTNTVRIEGVDRLRGARHEIIPDRIEAGT
CHHHHHCCCCCCHHHHHHHHHHHHCCCEECCCCCEEEEECHHHHCCCHHHCCCHHHCCCC
YMMMTAAAGGDVVVENVIPEHLGTVIAKLVEAGQEVEEHGDCIRVRARPIRAVDVETQVY
EEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCEEC
PGFPTDLQSPWVALMGLADGISVVHETIFENRFGFTNELIRMGAKIKVDRNTGIIRGVKR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEECCCCHHHHHHH
YTGAPVEARDIRGGAALVTAALAAEGVTEVSGVQYIDRGYTRMEEKLAALGADIRRVPNG
HCCCCCCHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCC
SEQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA