Click here to switch to the map view.

The map label for this gene is argD [H]

Identifier: 51894017

GI number: 51894017

Start: 3105671

End: 3106894

Strand: Reverse

Name: argD [H]

Synonym: STH2881

Alternate gene names: 51894017

Gene position: 3106894-3105671 (Counterclockwise)

Preceding gene: 51894018

Following gene: 51894016

Centisome position: 87.12

GC content: 71.9

Gene sequence:

>1224_bases
ATGGCGGACGTGAGCGGATCGAGGAGCGCAGCCCTGATGGCCCGGGCGGACGCGCACACGATGAAGACCTACGGGCGTTA
CCCGATCGCCCTGGTCCGGGGGGAGGGGGTGCGCTGCTGGGATGCGGACGGCAAGGAGTACCTGGACTTCCTCGGCGGCA
TTGCCGTCAACGTGCTCGGCCATGCCCACCCGGCCCTGGTTTCGGCGATCGCCGACCAGGCGGCCCGGCTGATCCACTGC
TCCAACCTGTACTACAGCGAGCCCATGGCCGAGCTGGCCGAGCTGCTCACCCAGCACGGCGGGCTGGACCGGGTCTTCTT
CTGCAACTCGGGCGCCGAGGCCAATGAGGGCGCGATCAAGCTGGCCCGGAAGTACCAGTGGCGGAAGGGGCTCAAAGCGA
AGAACCGGATCGTGTCGCTGACCCACTCCTTCCACGGCCGCACCCTGGCCACGGTGACGGCCACGGCCAAGCCGGCGATC
CAGGAGGGCTTCGGGCCGCTGCCGGAGGGATTCGACTACGTGGAGGCCGGCGATGTGGCGGCGCTCAGGGCCGCGGTCAC
GGACCGGACCGCCGCGGTGATCGTGGAGCCGGTGCAGGGCGAGGGCGGCGTGCGGCCGCTGGCCCGGGAGTTCCTGGAGG
CGGCCCGGGCGATTTGCGACGAGCGGGGCGCCCTGCTGATCTTCGACGAGATCCAGTGCGGCATGGGCCGCGTGGGCCAC
CTCTTCGCCTACCAGGCCTTCGGGGTGAAGCCGGACATCCTCACCCTGGCGAAGGGGCTGGGCGGGGGCGTGCCCATCGG
GGCCGTGTGCGCGACGGAGGAGGCGGCCCGGGGATTCGCGCCCGGCGACCACGGCACCACCTTCGGCGGCAGCCCGCTGG
CGTGCGCCGCGGCCCTGGCGACGGTCAAGACGCTGCTCAGCGAGGACCTGCCCGCCCGGGCCGCAGCCATGGGCGAGTAC
CTGCTGGCGGGGCTGCGGCGGCTGCAGGCGAAGCATCCGGGCCTGGTGAAGGAGGTCCGGGGCATGGGGCTGATGCTGGG
GATCGAGCTCACCCGCCCGGCCAGGCCGGTGCTGGAGAAGTGCCACGAGCTCGGGCTGCTGGTCAACGTGACCGCCGACA
CCGTGGTGCGGCTGCTGCCGCCCTACATCATCACCGCGGCGGACTGCGACCGGGCGCTGGAGATTCTCGATCAGGCGCTG
GCGGCGGTGGGATCTGCAGGATAG

Upstream 100 bases:

>100_bases
TCCACATCATCGACGGCCGGGTGCCCCACAGCCTGCTGTTGGAGATCTTCACGGACGAGGGCGTCGGCACCATGGTGGTC
AAGTAGCGGAGGGGATGGCG

Downstream 100 bases:

>100_bases
TGCCCGCCCTGCTGGGCAGACCGGCGAAGGCCCTGGGGGCGCACGCTGGGCGTTACATCGCACAGAGGGATCTGCGGTCA
TGCACGCAGATCCCTCTGTG

Product: N-acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MADVSGSRSAALMARADAHTMKTYGRYPIALVRGEGVRCWDADGKEYLDFLGGIAVNVLGHAHPALVSAIADQAARLIHC
SNLYYSEPMAELAELLTQHGGLDRVFFCNSGAEANEGAIKLARKYQWRKGLKAKNRIVSLTHSFHGRTLATVTATAKPAI
QEGFGPLPEGFDYVEAGDVAALRAAVTDRTAAVIVEPVQGEGGVRPLAREFLEAARAICDERGALLIFDEIQCGMGRVGH
LFAYQAFGVKPDILTLAKGLGGGVPIGAVCATEEAARGFAPGDHGTTFGGSPLACAAALATVKTLLSEDLPARAAAMGEY
LLAGLRRLQAKHPGLVKEVRGMGLMLGIELTRPARPVLEKCHELGLLVNVTADTVVRLLPPYIITAADCDRALEILDQAL
AAVGSAG

Sequences:

>Translated_407_residues
MADVSGSRSAALMARADAHTMKTYGRYPIALVRGEGVRCWDADGKEYLDFLGGIAVNVLGHAHPALVSAIADQAARLIHC
SNLYYSEPMAELAELLTQHGGLDRVFFCNSGAEANEGAIKLARKYQWRKGLKAKNRIVSLTHSFHGRTLATVTATAKPAI
QEGFGPLPEGFDYVEAGDVAALRAAVTDRTAAVIVEPVQGEGGVRPLAREFLEAARAICDERGALLIFDEIQCGMGRVGH
LFAYQAFGVKPDILTLAKGLGGGVPIGAVCATEEAARGFAPGDHGTTFGGSPLACAAALATVKTLLSEDLPARAAAMGEY
LLAGLRRLQAKHPGLVKEVRGMGLMLGIELTRPARPVLEKCHELGLLVNVTADTVVRLLPPYIITAADCDRALEILDQAL
AAVGSAG
>Mature_406_residues
ADVSGSRSAALMARADAHTMKTYGRYPIALVRGEGVRCWDADGKEYLDFLGGIAVNVLGHAHPALVSAIADQAARLIHCS
NLYYSEPMAELAELLTQHGGLDRVFFCNSGAEANEGAIKLARKYQWRKGLKAKNRIVSLTHSFHGRTLATVTATAKPAIQ
EGFGPLPEGFDYVEAGDVAALRAAVTDRTAAVIVEPVQGEGGVRPLAREFLEAARAICDERGALLIFDEIQCGMGRVGHL
FAYQAFGVKPDILTLAKGLGGGVPIGAVCATEEAARGFAPGDHGTTFGGSPLACAAALATVKTLLSEDLPARAAAMGEYL
LAGLRRLQAKHPGLVKEVRGMGLMLGIELTRPARPVLEKCHELGLLVNVTADTVVRLLPPYIITAADCDRALEILDQALA
AVGSAG

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=400, Percent_Identity=34.75, Blast_Score=237, Evalue=2e-62,
Organism=Homo sapiens, GI13994255, Length=434, Percent_Identity=31.1059907834101, Blast_Score=186, Evalue=2e-47,
Organism=Homo sapiens, GI284507298, Length=300, Percent_Identity=36.3333333333333, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI37574042, Length=424, Percent_Identity=29.7169811320755, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI226442705, Length=423, Percent_Identity=28.8416075650118, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI24119277, Length=391, Percent_Identity=31.2020460358056, Blast_Score=155, Evalue=9e-38,
Organism=Homo sapiens, GI226442709, Length=393, Percent_Identity=29.5165394402036, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI188536080, Length=460, Percent_Identity=24.1304347826087, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI38679950, Length=460, Percent_Identity=24.1304347826087, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI38679946, Length=460, Percent_Identity=24.1304347826087, Blast_Score=99, Evalue=1e-20,
Organism=Escherichia coli, GI1788044, Length=382, Percent_Identity=43.717277486911, Blast_Score=320, Evalue=1e-88,
Organism=Escherichia coli, GI1789759, Length=401, Percent_Identity=42.3940149625935, Blast_Score=317, Evalue=8e-88,
Organism=Escherichia coli, GI145693181, Length=380, Percent_Identity=42.6315789473684, Blast_Score=265, Evalue=3e-72,
Organism=Escherichia coli, GI1789016, Length=428, Percent_Identity=34.8130841121495, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI1787560, Length=420, Percent_Identity=34.0476190476191, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1786991, Length=401, Percent_Identity=32.4189526184539, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1786349, Length=351, Percent_Identity=31.6239316239316, Blast_Score=133, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI25144271, Length=400, Percent_Identity=35.5, Blast_Score=245, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI32564660, Length=433, Percent_Identity=31.1778290993072, Blast_Score=209, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI25144274, Length=264, Percent_Identity=35.6060606060606, Blast_Score=164, Evalue=9e-41,
Organism=Caenorhabditis elegans, GI71992977, Length=450, Percent_Identity=29.7777777777778, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71981843, Length=191, Percent_Identity=33.5078534031414, Blast_Score=111, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17541228, Length=459, Percent_Identity=25.2723311546841, Blast_Score=97, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6324432, Length=401, Percent_Identity=38.4039900249377, Blast_Score=279, Evalue=7e-76,
Organism=Saccharomyces cerevisiae, GI6323470, Length=424, Percent_Identity=33.9622641509434, Blast_Score=232, Evalue=7e-62,
Organism=Saccharomyces cerevisiae, GI6324386, Length=416, Percent_Identity=24.5192307692308, Blast_Score=111, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6321456, Length=366, Percent_Identity=26.775956284153, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21357415, Length=405, Percent_Identity=36.2962962962963, Blast_Score=259, Evalue=3e-69,
Organism=Drosophila melanogaster, GI161085790, Length=430, Percent_Identity=30.6976744186047, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI28574759, Length=431, Percent_Identity=30.8584686774942, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI21356575, Length=425, Percent_Identity=30.5882352941176, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI281366494, Length=409, Percent_Identity=25.4278728606357, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24667139, Length=409, Percent_Identity=25.4278728606357, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24667143, Length=409, Percent_Identity=25.4278728606357, Blast_Score=96, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42843; Mature: 42712

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADVSGSRSAALMARADAHTMKTYGRYPIALVRGEGVRCWDADGKEYLDFLGGIAVNVLG
CCCCCCCCCHHHEEHHHHHHHHHCCCCCEEEEECCCEEEECCCCHHHHHHHHHHHHHHHH
HAHPALVSAIADQAARLIHCSNLYYSEPMAELAELLTQHGGLDRVFFCNSGAEANEGAIK
CCHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHH
LARKYQWRKGLKAKNRIVSLTHSFHGRTLATVTATAKPAIQEGFGPLPEGFDYVEAGDVA
HHHHHHHHHCCCHHHHHEEEECCCCCCEEEEEEECCCHHHHHCCCCCCCCCCCCCCCCHH
ALRAAVTDRTAAVIVEPVQGEGGVRPLAREFLEAARAICDERGALLIFDEIQCGMGRVGH
HHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHH
LFAYQAFGVKPDILTLAKGLGGGVPIGAVCATEEAARGFAPGDHGTTFGGSPLACAAALA
HHHHHHCCCCCHHHHHHHHCCCCCCCCCEECCHHHHCCCCCCCCCCCCCCCHHHHHHHHH
TVKTLLSEDLPARAAAMGEYLLAGLRRLQAKHPGLVKEVRGMGLMLGIELTRPARPVLEK
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCEEEEEEEECCCCHHHHHH
CHELGLLVNVTADTVVRLLPPYIITAADCDRALEILDQALAAVGSAG
HHHCCEEEEEHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ADVSGSRSAALMARADAHTMKTYGRYPIALVRGEGVRCWDADGKEYLDFLGGIAVNVLG
CCCCCCCCHHHEEHHHHHHHHHCCCCCEEEEECCCEEEECCCCHHHHHHHHHHHHHHHH
HAHPALVSAIADQAARLIHCSNLYYSEPMAELAELLTQHGGLDRVFFCNSGAEANEGAIK
CCHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHH
LARKYQWRKGLKAKNRIVSLTHSFHGRTLATVTATAKPAIQEGFGPLPEGFDYVEAGDVA
HHHHHHHHHCCCHHHHHEEEECCCCCCEEEEEEECCCHHHHHCCCCCCCCCCCCCCCCHH
ALRAAVTDRTAAVIVEPVQGEGGVRPLAREFLEAARAICDERGALLIFDEIQCGMGRVGH
HHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHH
LFAYQAFGVKPDILTLAKGLGGGVPIGAVCATEEAARGFAPGDHGTTFGGSPLACAAALA
HHHHHHCCCCCHHHHHHHHCCCCCCCCCEECCHHHHCCCCCCCCCCCCCCCHHHHHHHHH
TVKTLLSEDLPARAAAMGEYLLAGLRRLQAKHPGLVKEVRGMGLMLGIELTRPARPVLEK
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCEEEEEEEECCCCHHHHHH
CHELGLLVNVTADTVVRLLPPYIITAADCDRALEILDQALAAVGSAG
HHHCCEEEEEHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]