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The map label for this gene is argB

Identifier: 51894018

GI number: 51894018

Start: 3106909

End: 3107790

Strand: Reverse

Name: argB

Synonym: STH2882

Alternate gene names: 51894018

Gene position: 3107790-3106909 (Counterclockwise)

Preceding gene: 51894019

Following gene: 51894017

Centisome position: 87.15

GC content: 69.39

Gene sequence:

>882_bases
GTGGATCAGCAGGCGCTGGACAAGGCGGCGGTGCTGGCGGAGGCGCTGCCGTACATCCGCGAGTTCTCGGGCAAGACGGT
GGTCATCAAGTACGGCGGGGCGGCGATGGCCGCCGCCGATCTGAAGGCCGCGGTCATGCAGGACATCGCCCTGATGAAGT
ACGTGGGCATGCACCCGATCGTGGTGCACGGCGGCGGGCCGGAGGTGTCGGAGTTGGCCCGGCGGATGGGCATCGAGCCC
CAGTTCGTGGACGGGCTGCGGGTGACCGACGCGGCCACCATGGAGATCGCTCAGATGGTGCTGGTGGGCAAGACGAACCG
GGAGATCGTCACCCACCTGTGCGCCCAGGGCGTGAAGGCGGTGGGCCTCTCGGGGCAGGACGCCGGCCTCATCCGGGCCG
CAAGGCACCTGCACCGCTCCCGGGAGACCGGGGAGATGGTGGACCTGGGCTTTGTGGGAGACGTGGCCGCGGTGGACACC
GAGGTGCTGACGACGCTCACCACCGCCGGCTACGTGCCGGTGATCGCCCCCATCGGGGTGGGGCCCGGCGGGCAACCCTA
TAACATCAACGCAGACACGGTGGCCGGCGCCATCGCCGCGGCCATGAAGGCGGAGAAGCTGGTGCTGCTCACCGACGTGG
AGGGGGTCCGGGCCGACAAGGATGACCCCTCCAGCCTGCTGAGCCGGGTGACGGCGCAGGAGGTCAAGTCCTGGATCGCC
CGGGGCAGACTGCAGGGCGGGATGATCCCGAAACTCCAGTGCTGCCTGACGGCCCTGGAGGGCGGCGTCAACCGGGTCCA
CATCATCGACGGCCGGGTGCCCCACAGCCTGCTGTTGGAGATCTTCACGGACGAGGGCGTCGGCACCATGGTGGTCAAGT
AG

Upstream 100 bases:

>100_bases
GGGAAGGGAGCCGCTGCCCATGTGAGGGCGGCCGGCTCCCCTTGAATATGCATGCACACTGAAGTATAATTATGCAATCA
CACCCCAGGAGGCGGGTTCC

Downstream 100 bases:

>100_bases
CGGAGGGGATGGCGATGGCGGACGTGAGCGGATCGAGGAGCGCAGCCCTGATGGCCCGGGCGGACGCGCACACGATGAAG
ACCTACGGGCGTTACCCGAT

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MDQQALDKAAVLAEALPYIREFSGKTVVIKYGGAAMAAADLKAAVMQDIALMKYVGMHPIVVHGGGPEVSELARRMGIEP
QFVDGLRVTDAATMEIAQMVLVGKTNREIVTHLCAQGVKAVGLSGQDAGLIRAARHLHRSRETGEMVDLGFVGDVAAVDT
EVLTTLTTAGYVPVIAPIGVGPGGQPYNINADTVAGAIAAAMKAEKLVLLTDVEGVRADKDDPSSLLSRVTAQEVKSWIA
RGRLQGGMIPKLQCCLTALEGGVNRVHIIDGRVPHSLLLEIFTDEGVGTMVVK

Sequences:

>Translated_293_residues
MDQQALDKAAVLAEALPYIREFSGKTVVIKYGGAAMAAADLKAAVMQDIALMKYVGMHPIVVHGGGPEVSELARRMGIEP
QFVDGLRVTDAATMEIAQMVLVGKTNREIVTHLCAQGVKAVGLSGQDAGLIRAARHLHRSRETGEMVDLGFVGDVAAVDT
EVLTTLTTAGYVPVIAPIGVGPGGQPYNINADTVAGAIAAAMKAEKLVLLTDVEGVRADKDDPSSLLSRVTAQEVKSWIA
RGRLQGGMIPKLQCCLTALEGGVNRVHIIDGRVPHSLLLEIFTDEGVGTMVVK
>Mature_293_residues
MDQQALDKAAVLAEALPYIREFSGKTVVIKYGGAAMAAADLKAAVMQDIALMKYVGMHPIVVHGGGPEVSELARRMGIEP
QFVDGLRVTDAATMEIAQMVLVGKTNREIVTHLCAQGVKAVGLSGQDAGLIRAARHLHRSRETGEMVDLGFVGDVAAVDT
EVLTTLTTAGYVPVIAPIGVGPGGQPYNINADTVAGAIAAAMKAEKLVLLTDVEGVRADKDDPSSLLSRVTAQEVKSWIA
RGRLQGGMIPKLQCCLTALEGGVNRVHIIDGRVPHSLLLEIFTDEGVGTMVVK

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI1789181, Length=287, Percent_Identity=26.4808362369338, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI145693208, Length=235, Percent_Identity=30.2127659574468, Blast_Score=78, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6320913, Length=297, Percent_Identity=28.2828282828283, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGB_SYMTH (Q67KD3)

Other databases:

- EMBL:   AP006840
- RefSeq:   YP_076709.1
- ProteinModelPortal:   Q67KD3
- SMR:   Q67KD3
- GeneID:   2982144
- GenomeReviews:   AP006840_GR
- KEGG:   sth:STH2882
- NMPDR:   fig|292459.1.peg.2757
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- BioCyc:   STHE292459:STH2882-MONOMER
- BRENDA:   2.7.2.8
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- PRINTS:   PR00474
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 30825; Mature: 30825

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: BINDING 87-87 BINDING 188-188

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQQALDKAAVLAEALPYIREFSGKTVVIKYGGAAMAAADLKAAVMQDIALMKYVGMHPI
CCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCE
VVHGGGPEVSELARRMGIEPQFVDGLRVTDAATMEIAQMVLVGKTNREIVTHLCAQGVKA
EEECCCCCHHHHHHHHCCCCCHHCCEEECHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHE
VGLSGQDAGLIRAARHLHRSRETGEMVDLGFVGDVAAVDTEVLTTLTTAGYVPVIAPIGV
ECCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCC
GPGGQPYNINADTVAGAIAAAMKAEKLVLLTDVEGVRADKDDPSSLLSRVTAQEVKSWIA
CCCCCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
RGRLQGGMIPKLQCCLTALEGGVNRVHIIDGRVPHSLLLEIFTDEGVGTMVVK
HCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEEC
>Mature Secondary Structure
MDQQALDKAAVLAEALPYIREFSGKTVVIKYGGAAMAAADLKAAVMQDIALMKYVGMHPI
CCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCE
VVHGGGPEVSELARRMGIEPQFVDGLRVTDAATMEIAQMVLVGKTNREIVTHLCAQGVKA
EEECCCCCHHHHHHHHCCCCCHHCCEEECHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHE
VGLSGQDAGLIRAARHLHRSRETGEMVDLGFVGDVAAVDTEVLTTLTTAGYVPVIAPIGV
ECCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCC
GPGGQPYNINADTVAGAIAAAMKAEKLVLLTDVEGVRADKDDPSSLLSRVTAQEVKSWIA
CCCCCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
RGRLQGGMIPKLQCCLTALEGGVNRVHIIDGRVPHSLLLEIFTDEGVGTMVVK
HCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA