Click here to switch to the map view.

The map label for this gene is hisK [H]

Identifier: 51893712

GI number: 51893712

Start: 2758475

End: 2759290

Strand: Reverse

Name: hisK [H]

Synonym: STH2574

Alternate gene names: 51893712

Gene position: 2759290-2758475 (Counterclockwise)

Preceding gene: 51893715

Following gene: 51893709

Centisome position: 77.37

GC content: 69.73

Gene sequence:

>816_bases
GTGCTGAACCGGCTCGCGGATTACCACATGCACACGGTGCGCTGCGGCCACGCCGTGGGCGCCATGGAGGCCTATGTCGA
GACCGCCATCGCGCGGGGGCTGGGAGAGATCGGCTTTTCGGACCACGTGCCCATGTACTGGCTGCCGGAGGAGCGGCGCG
ACCCCACCGGCGCGATGGCGATGGAGGAGCTGGAGGCGTACGTTTCCGACGTCCTGCGCCTCCGGGAGCGCTACCCCGAG
ATTCCCATCCGGCTGGGGCTGGAAGCCGATTTCATCCCCGGGCACGAGGAGGAGCTGGTTCGGCTGCTGGAGCCGTACCC
CTGGGACTACGTGATCGGGTCGGTCCACTTCCTGGACGACTGGAACTTCGATCATCCCGACCTGGTGCACCGCTACGCCG
AGTGGGACATCGACGTGCTGTACGACCGGTTCTTCGCCCTGGAGCGGGCGGCGGCCGAGAGCGGCCTCTTTGACATCCTC
GCCCACATCGACCTGATCAAGAAGTTCGGCCACCGGCCGCGCGGAGATCAGAGCGAGGCCTACGCGGCCCTGGCCGATGC
CATCGCCCGGTCCGGCGTCGCGATCGAGCTGTCCACCGCCGGGCTGCGCAAGCCCGTGGGCGAGTATTACCCCGCCCCGG
CCCTGCTGAAAGCCTGCTGCGCCCGCGGGATCCCGGTGGTCATCTCGTCGGACGCCCACGCCCCGGAGGAGGTCGGCTGG
GGGTTCGCAGAGGCGCGGGCGCTGGCCCTGGAGGTCGGGTTCACCCACACCGCCCGGTTTGCCGGTCGGCGGCGCCAGAT
GGTGCCCCTGTCCTGA

Upstream 100 bases:

>100_bases
CATCCGCGCCGGAACCGGAAGTCCATGGGACGAAATCGCCGCGCCGGAAGGAGAGCGCGGGCCCCAAGGCGAACACCAGG
GCCAGGAAGGGGGATGCAGC

Downstream 100 bases:

>100_bases
GCCGGCCGGGCATCACGGATCCGAGCGGCCCCGCCAACGGCCACGGGCGGCTGACAGAAAGCGAGCGGGTCCTCCCTGAC
GGGGGCCCCGCTCGTCGTGT

Product: histidinol-phosphatase

Products: NA

Alternate protein names: HolPase [H]

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MLNRLADYHMHTVRCGHAVGAMEAYVETAIARGLGEIGFSDHVPMYWLPEERRDPTGAMAMEELEAYVSDVLRLRERYPE
IPIRLGLEADFIPGHEEELVRLLEPYPWDYVIGSVHFLDDWNFDHPDLVHRYAEWDIDVLYDRFFALERAAAESGLFDIL
AHIDLIKKFGHRPRGDQSEAYAALADAIARSGVAIELSTAGLRKPVGEYYPAPALLKACCARGIPVVISSDAHAPEEVGW
GFAEARALALEVGFTHTARFAGRRRQMVPLS

Sequences:

>Translated_271_residues
MLNRLADYHMHTVRCGHAVGAMEAYVETAIARGLGEIGFSDHVPMYWLPEERRDPTGAMAMEELEAYVSDVLRLRERYPE
IPIRLGLEADFIPGHEEELVRLLEPYPWDYVIGSVHFLDDWNFDHPDLVHRYAEWDIDVLYDRFFALERAAAESGLFDIL
AHIDLIKKFGHRPRGDQSEAYAALADAIARSGVAIELSTAGLRKPVGEYYPAPALLKACCARGIPVVISSDAHAPEEVGW
GFAEARALALEVGFTHTARFAGRRRQMVPLS
>Mature_271_residues
MLNRLADYHMHTVRCGHAVGAMEAYVETAIARGLGEIGFSDHVPMYWLPEERRDPTGAMAMEELEAYVSDVLRLRERYPE
IPIRLGLEADFIPGHEEELVRLLEPYPWDYVIGSVHFLDDWNFDHPDLVHRYAEWDIDVLYDRFFALERAAAESGLFDIL
AHIDLIKKFGHRPRGDQSEAYAALADAIARSGVAIELSTAGLRKPVGEYYPAPALLKACCARGIPVVISSDAHAPEEVGW
GFAEARALALEVGFTHTARFAGRRRQMVPLS

Specific function: Unknown

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHP hydrolase family. HisK subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010140
- InterPro:   IPR004013
- InterPro:   IPR016195 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =3.1.3.15 [H]

Molecular weight: Translated: 30444; Mature: 30444

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNRLADYHMHTVRCGHAVGAMEAYVETAIARGLGEIGFSDHVPMYWLPEERRDPTGAMA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHCCCCHHHH
MEELEAYVSDVLRLRERYPEIPIRLGLEADFIPGHEEELVRLLEPYPWDYVIGSVHFLDD
HHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHCCCCCHHHHCEEEEEEC
WNFDHPDLVHRYAEWDIDVLYDRFFALERAAAESGLFDILAHIDLIKKFGHRPRGDQSEA
CCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
YAALADAIARSGVAIELSTAGLRKPVGEYYPAPALLKACCARGIPVVISSDAHAPEEVGW
HHHHHHHHHHCCCEEEEECCHHHCCHHHHCCCHHHHHHHHHCCCCEEEECCCCCCHHHCC
GFAEARALALEVGFTHTARFAGRRRQMVPLS
CHHHHHHHHHHHCCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLNRLADYHMHTVRCGHAVGAMEAYVETAIARGLGEIGFSDHVPMYWLPEERRDPTGAMA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHCCCCHHHH
MEELEAYVSDVLRLRERYPEIPIRLGLEADFIPGHEEELVRLLEPYPWDYVIGSVHFLDD
HHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHCCCCCHHHHCEEEEEEC
WNFDHPDLVHRYAEWDIDVLYDRFFALERAAAESGLFDILAHIDLIKKFGHRPRGDQSEA
CCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
YAALADAIARSGVAIELSTAGLRKPVGEYYPAPALLKACCARGIPVVISSDAHAPEEVGW
HHHHHHHHHHCCCEEEEECCHHHCCHHHHCCCHHHHHHHHHCCCCEEEECCCCCCHHHCC
GFAEARALALEVGFTHTARFAGRRRQMVPLS
CHHHHHHHHHHHCCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]