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The map label for this gene is ttdB [H]

Identifier: 51893673

GI number: 51893673

Start: 2719917

End: 2720510

Strand: Reverse

Name: ttdB [H]

Synonym: STH2535

Alternate gene names: 51893673

Gene position: 2720510-2719917 (Counterclockwise)

Preceding gene: 51893674

Following gene: 51893672

Centisome position: 76.29

GC content: 70.71

Gene sequence:

>594_bases
ATGGCCCGCGTCCACATCACCACGCCCGTCACCCCGGAGCAGGTGCGCCAGATCCGGGCCGGCGACGAGGTGATCATCAC
CGGCGAGATCTACACGGCCCGGGACGCCGCCCACAAGCGCATGGTGGAGGACCTGGCGGCCGGGCGGCCGCTGCCCTTCG
ACCCGGAGGGCGCGGTCATCTACTACGTCGGGCCGACGCCGCCCAAGCCCGGACAGGCGATCGGCTCGGCCGGCCCCACC
ACCTCCTACCGCATGGACAAGTACACGCCGGAGATTCTCCGGCACGGCGTGCGGCTGGTCATCGGCAAGGGGTACCGGGG
TGACGAGGTCAAGGCCGCCCTGCAGGAGTATGGCGCCGCTTACCTGGTCGCCACCGGCGGTGCGGGCGCGCTCCTGGCCA
AGCGGATCGAGGAGGCCGAGGTGGTCGCGTACGAGGATCTGGGCCCCGAGGCGGTTCGCCGTCTGCGGGTGCGGGAGTTC
CCCACCATCTGCATCAACGACGTGTACGGCGGCGATCAGTACTTCACCGGGCAGTCCCAGTGGGTGAAGCCGGACGCCAT
GGTGAAGCCCAAGCCGCCCGTGGCCAGCGAGTAG

Upstream 100 bases:

>100_bases
TGGCCGTGCACATTGAGGTCATGGGCTGCCACATCACCGCCCTGCCCGTGGCCGTGAACATCGAGTGCCACAGCCACCGG
CACAAGGAGGTGACGCTCTG

Downstream 100 bases:

>100_bases
CCGCGGCGCGGGAACCCCCGGGGCAGGGGGGCGGCGGACGACCGGCGCACAGGCCCCGGCAGCATCGGCGGACGCCGGGG
CCTTCGCGTGCGGGCGGCGG

Product: fumarate hydratase subunit B

Products: NA

Alternate protein names: L-TTD beta [H]

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MARVHITTPVTPEQVRQIRAGDEVIITGEIYTARDAAHKRMVEDLAAGRPLPFDPEGAVIYYVGPTPPKPGQAIGSAGPT
TSYRMDKYTPEILRHGVRLVIGKGYRGDEVKAALQEYGAAYLVATGGAGALLAKRIEEAEVVAYEDLGPEAVRRLRVREF
PTICINDVYGGDQYFTGQSQWVKPDAMVKPKPPVASE

Sequences:

>Translated_197_residues
MARVHITTPVTPEQVRQIRAGDEVIITGEIYTARDAAHKRMVEDLAAGRPLPFDPEGAVIYYVGPTPPKPGQAIGSAGPT
TSYRMDKYTPEILRHGVRLVIGKGYRGDEVKAALQEYGAAYLVATGGAGALLAKRIEEAEVVAYEDLGPEAVRRLRVREF
PTICINDVYGGDQYFTGQSQWVKPDAMVKPKPPVASE
>Mature_196_residues
ARVHITTPVTPEQVRQIRAGDEVIITGEIYTARDAAHKRMVEDLAAGRPLPFDPEGAVIYYVGPTPPKPGQAIGSAGPTT
SYRMDKYTPEILRHGVRLVIGKGYRGDEVKAALQEYGAAYLVATGGAGALLAKRIEEAEVVAYEDLGPEAVRRLRVREFP
TICINDVYGGDQYFTGQSQWVKPDAMVKPKPPVASE

Specific function: Unknown

COG id: COG1838

COG function: function code C; Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789443, Length=172, Percent_Identity=37.2093023255814, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790564, Length=163, Percent_Identity=36.8098159509202, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1787897, Length=191, Percent_Identity=34.0314136125654, Blast_Score=97, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004647 [H]

Pfam domain/function: PF05683 Fumerase_C [H]

EC number: =4.2.1.32 [H]

Molecular weight: Translated: 21437; Mature: 21306

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARVHITTPVTPEQVRQIRAGDEVIITGEIYTARDAAHKRMVEDLAAGRPLPFDPEGAVI
CCEEEEECCCCHHHHHHHHCCCEEEEECCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCEE
YYVGPTPPKPGQAIGSAGPTTSYRMDKYTPEILRHGVRLVIGKGYRGDEVKAALQEYGAA
EEECCCCCCCCCCCCCCCCCCCEECCCCCHHHHHCCEEEEEECCCCCHHHHHHHHHCCCE
YLVATGGAGALLAKRIEEAEVVAYEDLGPEAVRRLRVREFPTICINDVYGGDQYFTGQSQ
EEEEECCCHHHHHHHHHHHHEEEECCCCHHHHHHHHHHCCCEEEEECCCCCCEEECCCCC
WVKPDAMVKPKPPVASE
CCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ARVHITTPVTPEQVRQIRAGDEVIITGEIYTARDAAHKRMVEDLAAGRPLPFDPEGAVI
CEEEEECCCCHHHHHHHHCCCEEEEECCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCEE
YYVGPTPPKPGQAIGSAGPTTSYRMDKYTPEILRHGVRLVIGKGYRGDEVKAALQEYGAA
EEECCCCCCCCCCCCCCCCCCCEECCCCCHHHHHCCEEEEEECCCCCHHHHHHHHHCCCE
YLVATGGAGALLAKRIEEAEVVAYEDLGPEAVRRLRVREFPTICINDVYGGDQYFTGQSQ
EEEEECCCHHHHHHHHHHHHEEEECCCCHHHHHHHHHHCCCEEEEECCCCCCEEECCCCC
WVKPDAMVKPKPPVASE
CCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]