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The map label for this gene is trxB [H]

Identifier: 51893651

GI number: 51893651

Start: 2698822

End: 2699397

Strand: Reverse

Name: trxB [H]

Synonym: STH2513

Alternate gene names: 51893651

Gene position: 2699397-2698822 (Counterclockwise)

Preceding gene: 51893652

Following gene: 51893648

Centisome position: 75.7

GC content: 72.4

Gene sequence:

>576_bases
ATGTACGACGTCGCGATCGTGGGCGCCGGGCCCGCCGGTGCGAGTGCCGCAACGTTCACCGCCCGGGCCGGGCTGAAGAC
GCTGCTGCTGGACGCCGACCAGTCCATGACCCGCCGTGCCTGGATTCCGAACCATCTCGGCTTCCCCGACGGGGTGACCG
GCAACGACCTGGTGGACCTGGGCAAGAAGCAGGCGCAGACCGCCGGGGCCAACCTGGTGAAGGCCAAGGTGACGGCGGTG
CGCCGCGAGGGTGAGGGGTTCCGCCTGGAGACGGAGGGCGGCGAGGCCTACGAGGCCCGCCAGGTCATCCTCTGCCTGGG
CGCCAACTGCGAGCTGGCCCGCCAGGCCGGCGCGGAGATCGTCGAGGGGCCCGAACCCCGGATCAAGGAGGTCGTTGCCG
TGGACCGGGAGGGCCGGACCCGGGTCGAGGGCCTGTGGGCCGCGGGGACGTGCGCCGGCACCAGCGTGCACACCATCATC
ACCGCCGGCGACGGGGCGCGGGTGGCCATCAACCTGATCAGCGCCGTTAAGGGCGCCCGGCACGTGGACCACGAGGTCAT
GCCGGCCAGCAAGTAG

Upstream 100 bases:

>100_bases
TGCCCCGGGGGTGCCCGAACCTACGGTCGGTTACACCGCTCCCTTCGGGGAGGAAACGTCGTCTAACTAACGGAATAAGA
ATGTAAAGGAGGAAGCAGGA

Downstream 100 bases:

>100_bases
CCGAACGCGTACGGCGGGCGGCTCCTTCCCAACCCGGGAGGAGCCGCCCGCTGTTTGCGTCAGTGCGGGCCAGGGCTCCA
ACCCCGCCCCGCGATGGGCG

Product: putative thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MYDVAIVGAGPAGASAATFTARAGLKTLLLDADQSMTRRAWIPNHLGFPDGVTGNDLVDLGKKQAQTAGANLVKAKVTAV
RREGEGFRLETEGGEAYEARQVILCLGANCELARQAGAEIVEGPEPRIKEVVAVDREGRTRVEGLWAAGTCAGTSVHTII
TAGDGARVAINLISAVKGARHVDHEVMPASK

Sequences:

>Translated_191_residues
MYDVAIVGAGPAGASAATFTARAGLKTLLLDADQSMTRRAWIPNHLGFPDGVTGNDLVDLGKKQAQTAGANLVKAKVTAV
RREGEGFRLETEGGEAYEARQVILCLGANCELARQAGAEIVEGPEPRIKEVVAVDREGRTRVEGLWAAGTCAGTSVHTII
TAGDGARVAINLISAVKGARHVDHEVMPASK
>Mature_191_residues
MYDVAIVGAGPAGASAATFTARAGLKTLLLDADQSMTRRAWIPNHLGFPDGVTGNDLVDLGKKQAQTAGANLVKAKVTAV
RREGEGFRLETEGGEAYEARQVILCLGANCELARQAGAEIVEGPEPRIKEVVAVDREGRTRVEGLWAAGTCAGTSVHTII
TAGDGARVAINLISAVKGARHVDHEVMPASK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320560, Length=127, Percent_Identity=33.0708661417323, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321898, Length=129, Percent_Identity=31.7829457364341, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 19912; Mature: 19912

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDVAIVGAGPAGASAATFTARAGLKTLLLDADQSMTRRAWIPNHLGFPDGVTGNDLVDL
CCEEEEEECCCCCCCHHHHHHHCCCEEEEEECCCHHHHHCCCCCCCCCCCCCCCCHHHHH
GKKQAQTAGANLVKAKVTAVRREGEGFRLETEGGEAYEARQVILCLGANCELARQAGAEI
CHHHHHHHCCHHHHHHHHHHHCCCCCEEEECCCCCCHHHEEEEEEECCCCHHHHHCCCCC
VEGPEPRIKEVVAVDREGRTRVEGLWAAGTCAGTSVHTIITAGDGARVAINLISAVKGAR
CCCCCHHHHHHEEECCCCCCEEEEEEECCCCCCCEEEEEEECCCCCEEHHHHHHHHHHHH
HVDHEVMPASK
HCCCCCCCCCC
>Mature Secondary Structure
MYDVAIVGAGPAGASAATFTARAGLKTLLLDADQSMTRRAWIPNHLGFPDGVTGNDLVDL
CCEEEEEECCCCCCCHHHHHHHCCCEEEEEECCCHHHHHCCCCCCCCCCCCCCCCHHHHH
GKKQAQTAGANLVKAKVTAVRREGEGFRLETEGGEAYEARQVILCLGANCELARQAGAEI
CHHHHHHHCCHHHHHHHHHHHCCCCCEEEECCCCCCHHHEEEEEEECCCCHHHHHCCCCC
VEGPEPRIKEVVAVDREGRTRVEGLWAAGTCAGTSVHTIITAGDGARVAINLISAVKGAR
CCCCCHHHHHHEEECCCCCCEEEEEEECCCCCCCEEEEEEECCCCCEEHHHHHHHHHHHH
HVDHEVMPASK
HCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]