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The map label for this gene is dtd

Identifier: 51893568

GI number: 51893568

Start: 2613360

End: 2613815

Strand: Reverse

Name: dtd

Synonym: STH2430

Alternate gene names: 51893568

Gene position: 2613815-2613360 (Counterclockwise)

Preceding gene: 51893570

Following gene: 51893567

Centisome position: 73.3

GC content: 70.61

Gene sequence:

>456_bases
GTGATCTTGCGGGCAGTCGTGCAACGGGTCAGCCGCGCCCGGGTCACCGTCGGAGGCGAGGTGGTGGGCCAGATCGGCCC
CGGCTACGTGGTGCTGCTGGGCGTGTCCCGGGAGGACGACGAGGCCGCGGCGGACTACCTCGCCGAGAAGGTCGCCGGGC
TGCGGGTCTTCGAGGACGAGGAAGGCAAGATGAACCGGTCGATTCAGGAGGCTGGCGGAGCGGTCCTGGCCGTCAGCCAG
TTCACCCTGTACGGCGACGTGCGCCGGGGCCGGCGGCCCGGGTTCGACCGGGCGGCGCGCCCGGAGCAGGCGGAGCCGCT
GTACCGGCGGTTTGTGGAGCGGCTGCGCGCGCTGGGGCTTCACGTGGAGACCGGCCGGTTCCAGACGCATATGGAGGTGG
AACTGGTCAACGACGGGCCGGTCACCATCCTGATCGACTCGGAGAAGACGTTCTGA

Upstream 100 bases:

>100_bases
GGGCGCGCACCGTCCGTCGGATTAGGGCGCTGCCACAGGCCCGGGAGGAGTTCTTCGGGCAGGGAGCGTATCCCCCGGAT
AGCAACCGAGTGAGGAGGCA

Downstream 100 bases:

>100_bases
TCCCGCTCACTGAGAGGTAAAACCTTACAGATCTATGGCCTGTCCGGTTCGTCTCCGGTACCATTAAGAAAAGGGTACAG
CGGAGGTGGATCGGTATGGC

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MILRAVVQRVSRARVTVGGEVVGQIGPGYVVLLGVSREDDEAAADYLAEKVAGLRVFEDEEGKMNRSIQEAGGAVLAVSQ
FTLYGDVRRGRRPGFDRAARPEQAEPLYRRFVERLRALGLHVETGRFQTHMEVELVNDGPVTILIDSEKTF

Sequences:

>Translated_151_residues
MILRAVVQRVSRARVTVGGEVVGQIGPGYVVLLGVSREDDEAAADYLAEKVAGLRVFEDEEGKMNRSIQEAGGAVLAVSQ
FTLYGDVRRGRRPGFDRAARPEQAEPLYRRFVERLRALGLHVETGRFQTHMEVELVNDGPVTILIDSEKTF
>Mature_151_residues
MILRAVVQRVSRARVTVGGEVVGQIGPGYVVLLGVSREDDEAAADYLAEKVAGLRVFEDEEGKMNRSIQEAGGAVLAVSQ
FTLYGDVRRGRRPGFDRAARPEQAEPLYRRFVERLRALGLHVETGRFQTHMEVELVNDGPVTILIDSEKTF

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=148, Percent_Identity=45.945945945946, Blast_Score=122, Evalue=1e-28,
Organism=Escherichia coli, GI1790320, Length=141, Percent_Identity=56.7375886524823, Blast_Score=167, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI115533292, Length=149, Percent_Identity=42.9530201342282, Blast_Score=117, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6319982, Length=150, Percent_Identity=41.3333333333333, Blast_Score=121, Evalue=5e-29,
Organism=Drosophila melanogaster, GI281361569, Length=147, Percent_Identity=40.8163265306122, Blast_Score=116, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_SYMTH (Q67LN1)

Other databases:

- EMBL:   AP006840
- RefSeq:   YP_076259.1
- ProteinModelPortal:   Q67LN1
- SMR:   Q67LN1
- GeneID:   2979932
- GenomeReviews:   AP006840_GR
- KEGG:   sth:STH2430
- NMPDR:   fig|292459.1.peg.2326
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- ProtClustDB:   PRK05273
- BioCyc:   STHE292459:STH2430-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16727; Mature: 16727

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: ACT_SITE 82-82

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILRAVVQRVSRARVTVGGEVVGQIGPGYVVLLGVSREDDEAAADYLAEKVAGLRVFEDE
CHHHHHHHHHHHCEEEECCEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHCCEEEECC
EGKMNRSIQEAGGAVLAVSQFTLYGDVRRGRRPGFDRAARPEQAEPLYRRFVERLRALGL
CCCHHHHHHHCCCEEEEEEEHEEEHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
HVETGRFQTHMEVELVNDGPVTILIDSEKTF
EEECCCCEEEEEEEEECCCCEEEEECCCCCC
>Mature Secondary Structure
MILRAVVQRVSRARVTVGGEVVGQIGPGYVVLLGVSREDDEAAADYLAEKVAGLRVFEDE
CHHHHHHHHHHHCEEEECCEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHCCEEEECC
EGKMNRSIQEAGGAVLAVSQFTLYGDVRRGRRPGFDRAARPEQAEPLYRRFVERLRALGL
CCCHHHHHHHCCCEEEEEEEHEEEHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
HVETGRFQTHMEVELVNDGPVTILIDSEKTF
EEECCCCEEEEEEEEECCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA