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The map label for this gene is afsQ1 [H]

Identifier: 51893537

GI number: 51893537

Start: 2583801

End: 2584172

Strand: Reverse

Name: afsQ1 [H]

Synonym: STH2399

Alternate gene names: 51893537

Gene position: 2584172-2583801 (Counterclockwise)

Preceding gene: 51893538

Following gene: 51893536

Centisome position: 72.46

GC content: 65.32

Gene sequence:

>372_bases
ATGGCACTTCGGATCCTGCTGATCGAGGATGATCCCGACATTCAGCGCATGGTGCAGCTCTCCCTGAAGTTCCAGGGCGG
GCACGAGGTCAGCGTCGCCTCCGGGGGGCAGGAAGGCATCGCGAAGGCGGAGCAGGAGCGGCCGGATCTGATTCTGCTGG
ACGTGATGATGCCAGAGATGGACGGTTATGAGACCTGCCGGCGGCTGAAGGCCAACCCCGCCACCGCCTCCATCCCGATC
GTCTTCCTCAGCGCGCGGGCGCAGCAGTCCGAGATCGAGAAGGGCCGTTCGCTCGGGGCCATCGGCTATCTGGTCAAGCC
CTTCGACCCGATGACCCTGTCCGACCAGCTGGAGGCGATGCTCCGGGCCTAG

Upstream 100 bases:

>100_bases
GAGCGAATCACGCCTCGCCTACTCTGGAGACAGTAGACACAAGTGATGGGTAAGCCTACAATATGAGAAGAGATATTCGA
TAGGCGAAAGGAGGGGGCGA

Downstream 100 bases:

>100_bases
TCCCCGCGGTCGGGCGAAAGGAAGCGGTTCTGTTTGGACGTCACCCACATCCTGCGGGAAGTGTACTGGCACAGCCTCGA
CGGCATCGTCGTCGCCGACA

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 123; Mature: 122

Protein sequence:

>123_residues
MALRILLIEDDPDIQRMVQLSLKFQGGHEVSVASGGQEGIAKAEQERPDLILLDVMMPEMDGYETCRRLKANPATASIPI
VFLSARAQQSEIEKGRSLGAIGYLVKPFDPMTLSDQLEAMLRA

Sequences:

>Translated_123_residues
MALRILLIEDDPDIQRMVQLSLKFQGGHEVSVASGGQEGIAKAEQERPDLILLDVMMPEMDGYETCRRLKANPATASIPI
VFLSARAQQSEIEKGRSLGAIGYLVKPFDPMTLSDQLEAMLRA
>Mature_122_residues
ALRILLIEDDPDIQRMVQLSLKFQGGHEVSVASGGQEGIAKAEQERPDLILLDVMMPEMDGYETCRRLKANPATASIPIV
FLSARAQQSEIEKGRSLGAIGYLVKPFDPMTLSDQLEAMLRA

Specific function: Forms part of a two-component regulatory system AfsQ1/AfsQ2 involved in secondary metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=122, Percent_Identity=36.0655737704918, Blast_Score=77, Evalue=3e-16,
Organism=Escherichia coli, GI1790860, Length=119, Percent_Identity=34.453781512605, Blast_Score=70, Evalue=4e-14,
Organism=Escherichia coli, GI1788191, Length=119, Percent_Identity=30.2521008403361, Blast_Score=70, Evalue=6e-14,
Organism=Escherichia coli, GI87082012, Length=120, Percent_Identity=35, Blast_Score=69, Evalue=1e-13,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=29.2452830188679, Blast_Score=69, Evalue=1e-13,
Organism=Escherichia coli, GI1788394, Length=119, Percent_Identity=31.0924369747899, Blast_Score=66, Evalue=6e-13,
Organism=Escherichia coli, GI1788713, Length=115, Percent_Identity=34.7826086956522, Blast_Score=65, Evalue=1e-12,
Organism=Escherichia coli, GI1786911, Length=118, Percent_Identity=34.7457627118644, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1790437, Length=118, Percent_Identity=33.8983050847458, Blast_Score=64, Evalue=3e-12,
Organism=Escherichia coli, GI1786784, Length=120, Percent_Identity=32.5, Blast_Score=63, Evalue=5e-12,
Organism=Escherichia coli, GI1789809, Length=119, Percent_Identity=31.9327731092437, Blast_Score=61, Evalue=2e-11,
Organism=Escherichia coli, GI1787375, Length=120, Percent_Identity=27.5, Blast_Score=60, Evalue=4e-11,
Organism=Escherichia coli, GI1789149, Length=117, Percent_Identity=28.2051282051282, Blast_Score=59, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 13543; Mature: 13412

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALRILLIEDDPDIQRMVQLSLKFQGGHEVSVASGGQEGIAKAEQERPDLILLDVMMPEM
CEEEEEEEECCCCHHHHHHHHEEECCCCEEEEECCCCHHHHHHHHCCCCEEEEEEECCCC
DGYETCRRLKANPATASIPIVFLSARAQQSEIEKGRSLGAIGYLVKPFDPMTLSDQLEAM
CCHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHH
LRA
HCC
>Mature Secondary Structure 
ALRILLIEDDPDIQRMVQLSLKFQGGHEVSVASGGQEGIAKAEQERPDLILLDVMMPEM
EEEEEEEECCCCHHHHHHHHEEECCCCEEEEECCCCHHHHHHHHCCCCEEEEEEECCCC
DGYETCRRLKANPATASIPIVFLSARAQQSEIEKGRSLGAIGYLVKPFDPMTLSDQLEAM
CCHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHH
LRA
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1339426; 12000953 [H]