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The map label for this gene is resE [H]

Identifier: 51893536

GI number: 51893536

Start: 2581500

End: 2583767

Strand: Reverse

Name: resE [H]

Synonym: STH2398

Alternate gene names: 51893536

Gene position: 2583767-2581500 (Counterclockwise)

Preceding gene: 51893537

Following gene: 51893534

Centisome position: 72.45

GC content: 68.69

Gene sequence:

>2268_bases
TTGGACGTCACCCACATCCTGCGGGAAGTGTACTGGCACAGCCTCGACGGCATCGTCGTCGCCGACAAGGACACGGTGAT
CCTCGACGTCAACCCCGCGTACGAGGCGGTGACCGGTTACAGCCGTGACGAGCTGATCGGCAGAAAAACCAATATCGTAC
GCTCGGGACTCACCCCGCCGGAGGTCTTCCGCGACATGTGGACGCAGCTGGGCCGGCAGGGCAAGTGGGTCGGCGAGGTC
ATCAACCGGCACAAGAACGGCAACCTCTGGTACTCCTTCCTGTCCATCACCCGCATCGTGGACGAAGGAGGATCGGTGGT
TGCCTACGTCGGTATTGCCCGGGACATCACACAGCGGAAGGCGATGGAGCAGCAGCTCCGGCAGAACCTGGCCGAGATCC
AGTCCGCCCGGGAGCTGGCCCAGGCGCAGGCCACGCGGCTCACGGCGCTGCTGGACTCGGTGGGCGAGGCCATCATCATG
GTCGACACCCTGGGCATCTGCGTGGTGGCCAACCACCAGGCGGGCGGCATGCTGGGGCTGCCCGCGGAGCAGATCGTGGG
CAAATCGGTACATGAACTGCACGCCCTGGCCCTGCGGTCCCTGGGCGTCTCCGCCTTCCAGTGGCAGCCTGCCCCGAACG
GCGGGCCGCCCATCGAGCCGGAGACCAACGTCATTGAGACGCGGGAGCAGCGCCCCCGCGTCTTCCACGAGTTCGCCGCT
CCGGTGACGGACACGGAGGGTCACGTCCTCGGCCGCATCTATGTCTACCGCGACATCACCAAGGAGACCGAGCTGGACCG
GATGAAGACGGAGTTCATCGCTACGGTCTCCCACGAGCTGCGCACGCCGATGACCTCCATCAAGGGCGCGCTGGGGCTGG
TCCTGGGCGGGGCGGCCGGCGACCTGCCGCCGGAGGCGCGGGAGCTGCTCACGATCGCACGCAACAACACCGACCGGCTG
ATCCGGCTGATCAACGACATCCTGGACATCTCCCGCATCGAGGCCGGCAAGATGGAGATCCGCCGTGCGCCGCTGAGCCC
CGCTGACGTGGTGCGGCGAGCCGTGGAGGAGATGAACGCCTTTGCCCGGCAGCGCAACATCACCCTGACGACGGACGTGC
CGGAGGGGCTGGCGCGGGTGATGGCCGACGCCGACCGGCTGCACCAGGTGCTGGACAACCTGATCTCCAACGCCATCAAG
TTCTCGCCCCAGGGGAGCGAGGTACTCATCCGGGCCCGGGAGACCGGCGACGGGGTGCGGTTCGACGTCATCGACCGCGG
CCCGGGCATCCCCGCCGACCAGACGGGCCTGATCTTCGAACGCTTCTACCGGGTGGACAACGCGGCCTCCCGCAAGACCG
GCGGCACCGGCCTCGGCCTCACCATCTGCAAGGCGATCGTGGAGGAGCACGGCGGCCAGATCTGGGTCGAATCCGCGTTG
GGCGAGGGCTCCACCTTCTCGTTCACAATCCCGGTGGAGCCGGGCGGGCACGTCGCGGAGCCGCCCATCCCCGTGGGCAG
CCGGACGGTCCTGGTAGTGGACGACGATCCGGACATCGTGCGCATCATCATGCTCGCCCTGGAGCGGGAGGGGTTCCACG
CGGTCGGGGCCACCTCGGGCGAGCAGGCCCTGGAGATCGCCCGGAGCCGGCACGTGGACGTCATCACCCTCGACCTGATG
ATGCCCGGAGCCGACGGCGTGCAGGTGCTCCGGCAGCTGAAGCACGACCCGGCCACCCGCGACATCCCCGTGGTGGTGGT
CTCGGCCTACGGCGCCGGCAAGGAGCCGGAACTGGTGGCCACGGGCGTTTCGGGCATCGTGGCCAAGCCGATCGACGAGA
ACGACCTGCTGGCCACGATCCGGACCGTGCTGGGCACCTGGCGCGGCGAGCGGCCGCAGCCCTCCATCCTCGTGGTGGAC
GACGACCCGGACGTGCGGCGCATCGTCAGCGTGATGCTGGAGCGGGCGGGCTATGCGGTGCGCACGGCCCAAGACGGGCA
GGAGGCCTTCCGCATGATCATGGCCGAGCGGCCGGACCTCCTCATCCTCGACCTGATGATGCCGAACCTGGACGGCTTCC
AGCTGGTCCGGCTGCTGCGGCAGCGGCGCTGGACGCAGCAGATCCCGCTGCTGGTCCTCACCGCCCTGGACCTCACCGAG
GGTGAGAAGACCCTGCTCCAGCTGGGACCCACCCGGCACGTGACCAAGGGGCCGGTGATCCAGGAGGAGATCGTGGCGCG
GGTGCGGGAGTTGCTGGCTTCCCACTGA

Upstream 100 bases:

>100_bases
CTATCTGGTCAAGCCCTTCGACCCGATGACCCTGTCCGACCAGCTGGAGGCGATGCTCCGGGCCTAGTCCCCGCGGTCGG
GCGAAAGGAAGCGGTTCTGT

Downstream 100 bases:

>100_bases
GGAGCCCGACGCACCCCCACGCGCGCGGCCGGCCCCGAGGAGCGAGGTGCTCCCCGGGGCCGGCCCTTCAATCTACAGCG
TAGCCGCTTCGATCTCCGCC

Product: two-component hybrid sensor and regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 755; Mature: 755

Protein sequence:

>755_residues
MDVTHILREVYWHSLDGIVVADKDTVILDVNPAYEAVTGYSRDELIGRKTNIVRSGLTPPEVFRDMWTQLGRQGKWVGEV
INRHKNGNLWYSFLSITRIVDEGGSVVAYVGIARDITQRKAMEQQLRQNLAEIQSARELAQAQATRLTALLDSVGEAIIM
VDTLGICVVANHQAGGMLGLPAEQIVGKSVHELHALALRSLGVSAFQWQPAPNGGPPIEPETNVIETREQRPRVFHEFAA
PVTDTEGHVLGRIYVYRDITKETELDRMKTEFIATVSHELRTPMTSIKGALGLVLGGAAGDLPPEARELLTIARNNTDRL
IRLINDILDISRIEAGKMEIRRAPLSPADVVRRAVEEMNAFARQRNITLTTDVPEGLARVMADADRLHQVLDNLISNAIK
FSPQGSEVLIRARETGDGVRFDVIDRGPGIPADQTGLIFERFYRVDNAASRKTGGTGLGLTICKAIVEEHGGQIWVESAL
GEGSTFSFTIPVEPGGHVAEPPIPVGSRTVLVVDDDPDIVRIIMLALEREGFHAVGATSGEQALEIARSRHVDVITLDLM
MPGADGVQVLRQLKHDPATRDIPVVVVSAYGAGKEPELVATGVSGIVAKPIDENDLLATIRTVLGTWRGERPQPSILVVD
DDPDVRRIVSVMLERAGYAVRTAQDGQEAFRMIMAERPDLLILDLMMPNLDGFQLVRLLRQRRWTQQIPLLVLTALDLTE
GEKTLLQLGPTRHVTKGPVIQEEIVARVRELLASH

Sequences:

>Translated_755_residues
MDVTHILREVYWHSLDGIVVADKDTVILDVNPAYEAVTGYSRDELIGRKTNIVRSGLTPPEVFRDMWTQLGRQGKWVGEV
INRHKNGNLWYSFLSITRIVDEGGSVVAYVGIARDITQRKAMEQQLRQNLAEIQSARELAQAQATRLTALLDSVGEAIIM
VDTLGICVVANHQAGGMLGLPAEQIVGKSVHELHALALRSLGVSAFQWQPAPNGGPPIEPETNVIETREQRPRVFHEFAA
PVTDTEGHVLGRIYVYRDITKETELDRMKTEFIATVSHELRTPMTSIKGALGLVLGGAAGDLPPEARELLTIARNNTDRL
IRLINDILDISRIEAGKMEIRRAPLSPADVVRRAVEEMNAFARQRNITLTTDVPEGLARVMADADRLHQVLDNLISNAIK
FSPQGSEVLIRARETGDGVRFDVIDRGPGIPADQTGLIFERFYRVDNAASRKTGGTGLGLTICKAIVEEHGGQIWVESAL
GEGSTFSFTIPVEPGGHVAEPPIPVGSRTVLVVDDDPDIVRIIMLALEREGFHAVGATSGEQALEIARSRHVDVITLDLM
MPGADGVQVLRQLKHDPATRDIPVVVVSAYGAGKEPELVATGVSGIVAKPIDENDLLATIRTVLGTWRGERPQPSILVVD
DDPDVRRIVSVMLERAGYAVRTAQDGQEAFRMIMAERPDLLILDLMMPNLDGFQLVRLLRQRRWTQQIPLLVLTALDLTE
GEKTLLQLGPTRHVTKGPVIQEEIVARVRELLASH
>Mature_755_residues
MDVTHILREVYWHSLDGIVVADKDTVILDVNPAYEAVTGYSRDELIGRKTNIVRSGLTPPEVFRDMWTQLGRQGKWVGEV
INRHKNGNLWYSFLSITRIVDEGGSVVAYVGIARDITQRKAMEQQLRQNLAEIQSARELAQAQATRLTALLDSVGEAIIM
VDTLGICVVANHQAGGMLGLPAEQIVGKSVHELHALALRSLGVSAFQWQPAPNGGPPIEPETNVIETREQRPRVFHEFAA
PVTDTEGHVLGRIYVYRDITKETELDRMKTEFIATVSHELRTPMTSIKGALGLVLGGAAGDLPPEARELLTIARNNTDRL
IRLINDILDISRIEAGKMEIRRAPLSPADVVRRAVEEMNAFARQRNITLTTDVPEGLARVMADADRLHQVLDNLISNAIK
FSPQGSEVLIRARETGDGVRFDVIDRGPGIPADQTGLIFERFYRVDNAASRKTGGTGLGLTICKAIVEEHGGQIWVESAL
GEGSTFSFTIPVEPGGHVAEPPIPVGSRTVLVVDDDPDIVRIIMLALEREGFHAVGATSGEQALEIARSRHVDVITLDLM
MPGADGVQVLRQLKHDPATRDIPVVVVSAYGAGKEPELVATGVSGIVAKPIDENDLLATIRTVLGTWRGERPQPSILVVD
DDPDVRRIVSVMLERAGYAVRTAQDGQEAFRMIMAERPDLLILDLMMPNLDGFQLVRLLRQRRWTQQIPLLVLTALDLTE
GEKTLLQLGPTRHVTKGPVIQEEIVARVRELLASH

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=491, Percent_Identity=29.5315682281059, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI48994928, Length=491, Percent_Identity=28.9205702647658, Blast_Score=167, Evalue=3e-42,
Organism=Escherichia coli, GI1789149, Length=518, Percent_Identity=26.0617760617761, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI1788713, Length=396, Percent_Identity=29.7979797979798, Blast_Score=164, Evalue=2e-41,
Organism=Escherichia coli, GI1786600, Length=243, Percent_Identity=35.8024691358025, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI87081816, Length=393, Percent_Identity=29.0076335877863, Blast_Score=139, Evalue=6e-34,
Organism=Escherichia coli, GI1786912, Length=239, Percent_Identity=31.7991631799163, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788393, Length=259, Percent_Identity=29.3436293436293, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1790436, Length=254, Percent_Identity=33.0708661417323, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI87082128, Length=228, Percent_Identity=28.9473684210526, Blast_Score=108, Evalue=2e-24,
Organism=Escherichia coli, GI1786783, Length=225, Percent_Identity=29.3333333333333, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1790346, Length=220, Percent_Identity=32.2727272727273, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI1788549, Length=266, Percent_Identity=27.0676691729323, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1790551, Length=213, Percent_Identity=31.924882629108, Blast_Score=93, Evalue=7e-20,
Organism=Escherichia coli, GI1788279, Length=225, Percent_Identity=28.4444444444444, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1790861, Length=227, Percent_Identity=29.5154185022026, Blast_Score=83, Evalue=8e-17,
Organism=Escherichia coli, GI1787894, Length=227, Percent_Identity=27.7533039647577, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1790300, Length=233, Percent_Identity=27.8969957081545, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1786599, Length=119, Percent_Identity=34.453781512605, Blast_Score=76, Evalue=9e-15,
Organism=Escherichia coli, GI1789403, Length=205, Percent_Identity=28.2926829268293, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1786784, Length=118, Percent_Identity=34.7457627118644, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87082012, Length=120, Percent_Identity=31.6666666666667, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1787375, Length=117, Percent_Identity=35.8974358974359, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1790437, Length=118, Percent_Identity=34.7457627118644, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 82975; Mature: 82975

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVTHILREVYWHSLDGIVVADKDTVILDVNPAYEAVTGYSRDELIGRKTNIVRSGLTPP
CCHHHHHHHHHHHCCCCEEEECCCEEEEECCCHHHHHCCCCHHHHCCCHHHHHHCCCCCH
EVFRDMWTQLGRQGKWVGEVINRHKNGNLWYSFLSITRIVDEGGSVVAYVGIARDITQRK
HHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHH
AMEQQLRQNLAEIQSARELAQAQATRLTALLDSVGEAIIMVDTLGICVVANHQAGGMLGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCEEEEECCCCCCCCCC
PAEQIVGKSVHELHALALRSLGVSAFQWQPAPNGGPPIEPETNVIETREQRPRVFHEFAA
CHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCHHHHHHHCHHHHHHHCC
PVTDTEGHVLGRIYVYRDITKETELDRMKTEFIATVSHELRTPMTSIKGALGLVLGGAAG
CCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEECCCCC
DLPPEARELLTIARNNTDRLIRLINDILDISRIEAGKMEIRRAPLSPADVVRRAVEEMNA
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHH
FARQRNITLTTDVPEGLARVMADADRLHQVLDNLISNAIKFSPQGSEVLIRARETGDGVR
HHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEEECCCCCCE
FDVIDRGPGIPADQTGLIFERFYRVDNAASRKTGGTGLGLTICKAIVEEHGGQIWVESAL
EEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECC
GEGSTFSFTIPVEPGGHVAEPPIPVGSRTVLVVDDDPDIVRIIMLALEREGFHAVGATSG
CCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEECCCCH
EQALEIARSRHVDVITLDLMMPGADGVQVLRQLKHDPATRDIPVVVVSAYGAGKEPELVA
HHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCEEE
TGVSGIVAKPIDENDLLATIRTVLGTWRGERPQPSILVVDDDPDVRRIVSVMLERAGYAV
ECCCCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCEE
RTAQDGQEAFRMIMAERPDLLILDLMMPNLDGFQLVRLLRQRRWTQQIPLLVLTALDLTE
EECCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEHHCCCC
GEKTLLQLGPTRHVTKGPVIQEEIVARVRELLASH
CCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDVTHILREVYWHSLDGIVVADKDTVILDVNPAYEAVTGYSRDELIGRKTNIVRSGLTPP
CCHHHHHHHHHHHCCCCEEEECCCEEEEECCCHHHHHCCCCHHHHCCCHHHHHHCCCCCH
EVFRDMWTQLGRQGKWVGEVINRHKNGNLWYSFLSITRIVDEGGSVVAYVGIARDITQRK
HHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHH
AMEQQLRQNLAEIQSARELAQAQATRLTALLDSVGEAIIMVDTLGICVVANHQAGGMLGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCEEEEECCCCCCCCCC
PAEQIVGKSVHELHALALRSLGVSAFQWQPAPNGGPPIEPETNVIETREQRPRVFHEFAA
CHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCHHHHHHHCHHHHHHHCC
PVTDTEGHVLGRIYVYRDITKETELDRMKTEFIATVSHELRTPMTSIKGALGLVLGGAAG
CCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEECCCCC
DLPPEARELLTIARNNTDRLIRLINDILDISRIEAGKMEIRRAPLSPADVVRRAVEEMNA
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHH
FARQRNITLTTDVPEGLARVMADADRLHQVLDNLISNAIKFSPQGSEVLIRARETGDGVR
HHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEEECCCCCCE
FDVIDRGPGIPADQTGLIFERFYRVDNAASRKTGGTGLGLTICKAIVEEHGGQIWVESAL
EEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECC
GEGSTFSFTIPVEPGGHVAEPPIPVGSRTVLVVDDDPDIVRIIMLALEREGFHAVGATSG
CCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEECCCCH
EQALEIARSRHVDVITLDLMMPGADGVQVLRQLKHDPATRDIPVVVVSAYGAGKEPELVA
HHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCEEE
TGVSGIVAKPIDENDLLATIRTVLGTWRGERPQPSILVVDDDPDVRRIVSVMLERAGYAV
ECCCCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCEE
RTAQDGQEAFRMIMAERPDLLILDLMMPNLDGFQLVRLLRQRRWTQQIPLLVLTALDLTE
EECCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEHHCCCC
GEKTLLQLGPTRHVTKGPVIQEEIVARVRELLASH
CCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]