BacMap

Definition	Symbiobacterium thermophilum IAM 14863 chromosome, complete genome.
Accession	NC_006177
Length	3,566,135

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The map label for this gene is livG [H]

Identifier: 51893497

GI number: 51893497

Start: 2548671

End: 2549561

Strand: Reverse

Name: livG [H]

Synonym: STH2359

Alternate gene names: 51893497

Gene position: 2549561-2548671 (Counterclockwise)

Preceding gene: 51893498

Following gene: 51893496

Centisome position: 71.49

GC content: 73.74

Gene sequence:

>891_bases
GTGCAGGTCCTTTCGGTCCGGAACCTGGCCAAGCGCTTCGGCGGCCTCGACGCCGTGCGGTCCGTGAGCCTGGACGTCGG
GCCGGGCGAGACGGTGGCGGTCATCGGCCCCAACGGGGCGGGGAAGACCACGCTCTTTCAACTGATCGCCGGCGCCGAGC
GGCCCGACGGCGGACAGGTCTACCTGGAGGGGGAGCGCATCGACGGCCTGCCGGCGCACGTCATCGCCGCGAAGGGGATC
GCCCGCACCTTTCAGAACGGGCGGGTCTACGGGAACCTGACGGTCCTGGAGAACGTGCTTCTCGGGGCCCACACCCGGCT
GCAGGCGGAGTTCGGGCGGCCCGCGGGTCCCCTGACCGGTGTGCTGGGGGCGATCCGGGAGGTGATCGCGGCCATGGCCC
GCCCGGCCCGGCTCCGCCGCTTGGAGGCCGAGTTGGTGGAGGAGGCGGTGGAGATCCTCTCGCTCTTCGGCGATCGGCTG
CTGCCCCGGCTGCACCAGCCCGCCTACTCGCTCTCCTATGCCAACCGGCGTCGCACCGAGCTGGCCCGGGCGCTGGCCCT
GCGCCCGAAGATCCTGTTGCTCGACGAGCCTACCGCCGGCATGAACCCCACCGAGACCGAGGAGATGACCGAGGTCATCC
GGCTGCTGCAGGCCCGCGGGCACACGATCCTGCTCATCGAGCACAAGCTGGACGTCGTCAGCGCCCTGGCGCACCGGGTG
GTGGCCCTGGAGGCCGGGGAGGTGCTGGTGGCGGGCACGCCGGCGGAGGTCTGGTCCGACCGGCGGCTGGTGGAGGCCTA
CGTGGGCCGGAGCCCCGGCCGGCGGCAGCCGCCTGCGGCCGCGCCCGCACCGCCGGCCCAAGACGCACGCGCGCGGGCGG
CGGTCCACTGA

Upstream 100 bases:

>100_bases
CGGAGTACCGGTTCCTGGTCTACGGCCTGCTGCTTCTGGTCATGCTCAGGTTCCGGCCCCGGGGCCTCCTGAGCGCCGCA
TCGTGAGGAGGTGAACCCCC

Downstream 100 bases:

>100_bases
AGGAGGGAGACGAACGTGGCGGCCATCCTGGAACTGCGTGGGGTGGACACCTTCTACGGCCCCGTGCAGGTGCACTTCGG
CGTGAGCCTGACCGTGCGGG

Product: ABC transporter ATP-binding protein

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein G [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MQVLSVRNLAKRFGGLDAVRSVSLDVGPGETVAVIGPNGAGKTTLFQLIAGAERPDGGQVYLEGERIDGLPAHVIAAKGI
ARTFQNGRVYGNLTVLENVLLGAHTRLQAEFGRPAGPLTGVLGAIREVIAAMARPARLRRLEAELVEEAVEILSLFGDRL
LPRLHQPAYSLSYANRRRTELARALALRPKILLLDEPTAGMNPTETEEMTEVIRLLQARGHTILLIEHKLDVVSALAHRV
VALEAGEVLVAGTPAEVWSDRRLVEAYVGRSPGRRQPPAAAPAPPAQDARARAAVH

Sequences:

>Translated_296_residues
MQVLSVRNLAKRFGGLDAVRSVSLDVGPGETVAVIGPNGAGKTTLFQLIAGAERPDGGQVYLEGERIDGLPAHVIAAKGI
ARTFQNGRVYGNLTVLENVLLGAHTRLQAEFGRPAGPLTGVLGAIREVIAAMARPARLRRLEAELVEEAVEILSLFGDRL
LPRLHQPAYSLSYANRRRTELARALALRPKILLLDEPTAGMNPTETEEMTEVIRLLQARGHTILLIEHKLDVVSALAHRV
VALEAGEVLVAGTPAEVWSDRRLVEAYVGRSPGRRQPPAAAPAPPAQDARARAAVH
>Mature_296_residues
MQVLSVRNLAKRFGGLDAVRSVSLDVGPGETVAVIGPNGAGKTTLFQLIAGAERPDGGQVYLEGERIDGLPAHVIAAKGI
ARTFQNGRVYGNLTVLENVLLGAHTRLQAEFGRPAGPLTGVLGAIREVIAAMARPARLRRLEAELVEEAVEILSLFGDRL
LPRLHQPAYSLSYANRRRTELARALALRPKILLLDEPTAGMNPTETEEMTEVIRLLQARGHTILLIEHKLDVVSALAHRV
VALEAGEVLVAGTPAEVWSDRRLVEAYVGRSPGRRQPPAAAPAPPAQDARARAAVH

Specific function: Component of the leucine-specific transport system [H]

COG id: COG0411

COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI150417984, Length=282, Percent_Identity=26.9503546099291, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI156105685, Length=286, Percent_Identity=27.2727272727273, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI21536378, Length=243, Percent_Identity=25.5144032921811, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI255708477, Length=250, Percent_Identity=24.4, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI105990541, Length=259, Percent_Identity=26.2548262548263, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI9955968, Length=265, Percent_Identity=26.0377358490566, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI9955966, Length=265, Percent_Identity=26.0377358490566, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI45243524, Length=265, Percent_Identity=26.0377358490566, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI148612844, Length=246, Percent_Identity=28.0487804878049, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1789864, Length=270, Percent_Identity=38.1481481481481, Blast_Score=186, Evalue=1e-48,
Organism=Escherichia coli, GI1789593, Length=269, Percent_Identity=33.457249070632, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI87081709, Length=272, Percent_Identity=27.2058823529412, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI87081791, Length=257, Percent_Identity=28.7937743190661, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1788225, Length=286, Percent_Identity=28.3216783216783, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787029, Length=253, Percent_Identity=28.0632411067194, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1790525, Length=272, Percent_Identity=28.6764705882353, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI48995001, Length=271, Percent_Identity=28.4132841328413, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1788761, Length=269, Percent_Identity=30.1115241635688, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1790467, Length=286, Percent_Identity=28.6713286713287, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI87082268, Length=271, Percent_Identity=27.3062730627306, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788210, Length=270, Percent_Identity=26.6666666666667, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787792, Length=261, Percent_Identity=27.9693486590038, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1789672, Length=259, Percent_Identity=23.5521235521236, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787370, Length=263, Percent_Identity=28.1368821292776, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1786398, Length=265, Percent_Identity=30.188679245283, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1789991, Length=272, Percent_Identity=28.6764705882353, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1790190, Length=288, Percent_Identity=25.6944444444444, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788897, Length=241, Percent_Identity=26.1410788381743, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787712, Length=268, Percent_Identity=27.6119402985075, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1787089, Length=246, Percent_Identity=28.8617886178862, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1790544, Length=288, Percent_Identity=28.8194444444444, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082267, Length=273, Percent_Identity=28.5714285714286, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789032, Length=263, Percent_Identity=29.277566539924, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1786345, Length=256, Percent_Identity=29.296875, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI48994943, Length=285, Percent_Identity=27.0175438596491, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786253, Length=249, Percent_Identity=29.718875502008, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786803, Length=273, Percent_Identity=26.007326007326, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789873, Length=238, Percent_Identity=26.4705882352941, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788450, Length=275, Percent_Identity=26.1818181818182, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788644, Length=269, Percent_Identity=26.0223048327138, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787105, Length=237, Percent_Identity=27.4261603375527, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788506, Length=246, Percent_Identity=27.2357723577236, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI48994883, Length=267, Percent_Identity=25.8426966292135, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787112, Length=241, Percent_Identity=26.9709543568465, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789586, Length=257, Percent_Identity=26.4591439688716, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI2367384, Length=61, Percent_Identity=45.9016393442623, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=258, Percent_Identity=29.0697674418605, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17558664, Length=236, Percent_Identity=29.2372881355932, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71996809, Length=269, Percent_Identity=24.1635687732342, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193211015, Length=269, Percent_Identity=24.1635687732342, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193211017, Length=269, Percent_Identity=24.1635687732342, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17541710, Length=247, Percent_Identity=27.9352226720648, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI212646699, Length=234, Percent_Identity=22.6495726495727, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115533592, Length=258, Percent_Identity=25.5813953488372, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24659289, Length=241, Percent_Identity=27.8008298755187, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI281363262, Length=248, Percent_Identity=28.2258064516129, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24653245, Length=248, Percent_Identity=28.2258064516129, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI116007184, Length=245, Percent_Identity=25.7142857142857, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24641565, Length=245, Percent_Identity=24.8979591836735, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI221500365, Length=245, Percent_Identity=25.7142857142857, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI17136662, Length=236, Percent_Identity=26.6949152542373, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 31770; Mature: 31770

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVLSVRNLAKRFGGLDAVRSVSLDVGPGETVAVIGPNGAGKTTLFQLIAGAERPDGGQV
CCCHHHHHHHHHHCCHHHHHHEEEECCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCEE
YLEGERIDGLPAHVIAAKGIARTFQNGRVYGNLTVLENVLLGAHTRLQAEFGRPAGPLTG
EEECCCCCCCCHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCCHHHHHHHCCCCCCHHHH
VLGAIREVIAAMARPARLRRLEAELVEEAVEILSLFGDRLLPRLHQPAYSLSYANRRRTE
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LARALALRPKILLLDEPTAGMNPTETEEMTEVIRLLQARGHTILLIEHKLDVVSALAHRV
HHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHH
VALEAGEVLVAGTPAEVWSDRRLVEAYVGRSPGRRQPPAAAPAPPAQDARARAAVH
HHEECCCEEEECCCHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure
MQVLSVRNLAKRFGGLDAVRSVSLDVGPGETVAVIGPNGAGKTTLFQLIAGAERPDGGQV
CCCHHHHHHHHHHCCHHHHHHEEEECCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCEE
YLEGERIDGLPAHVIAAKGIARTFQNGRVYGNLTVLENVLLGAHTRLQAEFGRPAGPLTG
EEECCCCCCCCHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCCHHHHHHHCCCCCCHHHH
VLGAIREVIAAMARPARLRRLEAELVEEAVEILSLFGDRLLPRLHQPAYSLSYANRRRTE
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LARALALRPKILLLDEPTAGMNPTETEEMTEVIRLLQARGHTILLIEHKLDVVSALAHRV
HHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHH
VALEAGEVLVAGTPAEVWSDRRLVEAYVGRSPGRRQPPAAAPAPPAQDARARAAVH
HHEECCCEEEECCCHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]