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The map label for this gene is braD [H]

Identifier: 51893498

GI number: 51893498

Start: 2549576

End: 2551435

Strand: Reverse

Name: braD [H]

Synonym: STH2360

Alternate gene names: 51893498

Gene position: 2551435-2549576 (Counterclockwise)

Preceding gene: 51893499

Following gene: 51893497

Centisome position: 71.55

GC content: 71.83

Gene sequence:

>1860_bases
GTGGCGGCGCCTTTGCGATCTGGAACCCGTAGGAGGGGGAGCATGCTGGACCAGCTGATCAACGGCCTGGTGGTTGGCAA
CCTCTACGCCCTCACGGCGGTGGGCATCACCCAGATCTACGGCGTGGCCAACGTGATCAACTTCGCCCACGGCTCCCTCT
ACATGGTCGGCGCCTTCGTGGGCTGGATGGCGGTCACCTGGCTGGGCCTGCCGCTACTGCCCACCCTGCTGCTCGTGCTC
GTCGCCTCGGCCCTGCTGGGGCTGGCGGTGGAGCGGGTCGCCATCCGCCCCTTCGCCGGTTCTGGCCGGACGGTGCTGCT
GCTCACCACCATCGCCGCGGGGCTCGTCCTGGAGCAGGCGGCCCAGCTGATATGGGGGCCGGAGACCAAGGCCTTCCACA
CCCCCTTCGCCGACGTGCGGGTCCGGGTGGGCGGCGGCTTCCTCTCCTCCCTGGACCTGGTGATCCTGGCTGTGGGCTTG
ACCACCGCTCTGGCGCTCTGGCTCTTCCTGAAGCGGTCCCGCCTGGGCTGGGCGGTCCGGGCCACCGCCCAGGACCGGGA
GGCCGCCCTGCAGATGGGCGTCGACGTGAACCAGGTCAGCCGGGTCAGCTTCGCCATGGCCGGCGCCCTGGCCGGGGTGA
GCGGGCTCCTGGTGGGGCTGTACTACCACAGCGTCTACCCCACCATGGGCTTCTCCGCGAGCCTGAAGGGATTCACGGCG
GCCCTGCTGGGCGGATTGGGCAACATCCCCGGCGCGCTGGTGGGGGCGTACCTGCTGGGAACGGCGGAGTCGCTGGCGGT
GGCCTGGCTGGGCTCCACCTGGCGCGACCTGGTGGGCATCGGACTGCTGCTCGGCGTGCTGCTTTTCCGCCCCAACGGCC
TGTTCGCGGCCGCCCGGGCGCTGCTGCCCGAGCCCACTGCCGGCACTTTCATCCCGATCGGGCGGCCGCTGCCTATCCCC
CGGTGGGCGCTGCCCGCGGCGGGGGCCGTCGCCCTGGCCCTGCCGCTGGTGGTGCGGAACGGGTACTGGCTGCAGGTGCT
GGCGACCGCCTGGATCTTCGGCCTGCTGGCCATCAGCCTCAACCTGATTGCCGGGACGGCCGGGCAGATCTCCCTCGGGC
ACGCCGGCTTCCTGGCCCTGGGGGCGTACGCCTCGGCCATCCTCACCACCCGGCTGCAGTGGCCCTTCCTGCTGTCGCTG
GCTGTCGCGCCCGTCATCGCCGCCGCCGTCGGCGTGGTGCTTTGCTACCCGGCCCTGCGGCTCCGGGGGCAGTACCTGGC
GGTGGCCACCATCGGCCTGGGCCAGGGGATCGCGCTGGTGGCGCTCAACTGGACGGCACTGACCCGGGGGCCCCTGGGCA
TCAGCAACATCGCCCCGCCTGGCCTCTTCGGAGTGGAGATCACCTCGGCCGCGGGGTTCTACTGGCTGACCCTGACCCTG
CTGCTGGGCGGCATCTGGGTGGCGGAGCGGCTCTCCGGCTCGTACCTGGGCCGGGCGCTGCGGGCCGTGCGGGAGGACGA
GGTGGCCGCCCGGGCGTACGGGGTGGGGCTGGAGCGGTACAAGTCCATCGCCTTCGGCCTCAGCGCCTTCATCGCGGGCC
TCGCCGGCGTCCTGCTGGCGCACGCCTACACCTACATCGCGCCGGACACGTTCACCCACGCGATGTCGCTGCAGGTGCTG
ACGATGGTGGTGCTGGGCGGGCTGGACAACACCATCGGCGCCGTGGCGGGGGCCCTCGCCCTGATCGTCATCCCCGAGTC
CGCCCGGTTCCTGGCGGAGTACCGGTTCCTGGTCTACGGCCTGCTGCTTCTGGTCATGCTCAGGTTCCGGCCCCGGGGCC
TCCTGAGCGCCGCATCGTGA

Upstream 100 bases:

>100_bases
CTGGAGCAGGCCGAGCACCTGGAGACCATCCTGCAGGGCGCCACCGCCTTCGGCGAGGACCGGCGGCTCCGCAACCCCCG
CTTCGTACCGCTGGTGGTCC

Downstream 100 bases:

>100_bases
GGAGGTGAACCCCCGTGCAGGTCCTTTCGGTCCGGAACCTGGCCAAGCGCTTCGGCGGCCTCGACGCCGTGCGGTCCGTG
AGCCTGGACGTCGGGCCGGG

Product: ABC transporter permease protein

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 619; Mature: 618

Protein sequence:

>619_residues
MAAPLRSGTRRRGSMLDQLINGLVVGNLYALTAVGITQIYGVANVINFAHGSLYMVGAFVGWMAVTWLGLPLLPTLLLVL
VASALLGLAVERVAIRPFAGSGRTVLLLTTIAAGLVLEQAAQLIWGPETKAFHTPFADVRVRVGGGFLSSLDLVILAVGL
TTALALWLFLKRSRLGWAVRATAQDREAALQMGVDVNQVSRVSFAMAGALAGVSGLLVGLYYHSVYPTMGFSASLKGFTA
ALLGGLGNIPGALVGAYLLGTAESLAVAWLGSTWRDLVGIGLLLGVLLFRPNGLFAAARALLPEPTAGTFIPIGRPLPIP
RWALPAAGAVALALPLVVRNGYWLQVLATAWIFGLLAISLNLIAGTAGQISLGHAGFLALGAYASAILTTRLQWPFLLSL
AVAPVIAAAVGVVLCYPALRLRGQYLAVATIGLGQGIALVALNWTALTRGPLGISNIAPPGLFGVEITSAAGFYWLTLTL
LLGGIWVAERLSGSYLGRALRAVREDEVAARAYGVGLERYKSIAFGLSAFIAGLAGVLLAHAYTYIAPDTFTHAMSLQVL
TMVVLGGLDNTIGAVAGALALIVIPESARFLAEYRFLVYGLLLLVMLRFRPRGLLSAAS

Sequences:

>Translated_619_residues
MAAPLRSGTRRRGSMLDQLINGLVVGNLYALTAVGITQIYGVANVINFAHGSLYMVGAFVGWMAVTWLGLPLLPTLLLVL
VASALLGLAVERVAIRPFAGSGRTVLLLTTIAAGLVLEQAAQLIWGPETKAFHTPFADVRVRVGGGFLSSLDLVILAVGL
TTALALWLFLKRSRLGWAVRATAQDREAALQMGVDVNQVSRVSFAMAGALAGVSGLLVGLYYHSVYPTMGFSASLKGFTA
ALLGGLGNIPGALVGAYLLGTAESLAVAWLGSTWRDLVGIGLLLGVLLFRPNGLFAAARALLPEPTAGTFIPIGRPLPIP
RWALPAAGAVALALPLVVRNGYWLQVLATAWIFGLLAISLNLIAGTAGQISLGHAGFLALGAYASAILTTRLQWPFLLSL
AVAPVIAAAVGVVLCYPALRLRGQYLAVATIGLGQGIALVALNWTALTRGPLGISNIAPPGLFGVEITSAAGFYWLTLTL
LLGGIWVAERLSGSYLGRALRAVREDEVAARAYGVGLERYKSIAFGLSAFIAGLAGVLLAHAYTYIAPDTFTHAMSLQVL
TMVVLGGLDNTIGAVAGALALIVIPESARFLAEYRFLVYGLLLLVMLRFRPRGLLSAAS
>Mature_618_residues
AAPLRSGTRRRGSMLDQLINGLVVGNLYALTAVGITQIYGVANVINFAHGSLYMVGAFVGWMAVTWLGLPLLPTLLLVLV
ASALLGLAVERVAIRPFAGSGRTVLLLTTIAAGLVLEQAAQLIWGPETKAFHTPFADVRVRVGGGFLSSLDLVILAVGLT
TALALWLFLKRSRLGWAVRATAQDREAALQMGVDVNQVSRVSFAMAGALAGVSGLLVGLYYHSVYPTMGFSASLKGFTAA
LLGGLGNIPGALVGAYLLGTAESLAVAWLGSTWRDLVGIGLLLGVLLFRPNGLFAAARALLPEPTAGTFIPIGRPLPIPR
WALPAAGAVALALPLVVRNGYWLQVLATAWIFGLLAISLNLIAGTAGQISLGHAGFLALGAYASAILTTRLQWPFLLSLA
VAPVIAAAVGVVLCYPALRLRGQYLAVATIGLGQGIALVALNWTALTRGPLGISNIAPPGLFGVEITSAAGFYWLTLTLL
LGGIWVAERLSGSYLGRALRAVREDEVAARAYGVGLERYKSIAFGLSAFIAGLAGVLLAHAYTYIAPDTFTHAMSLQVLT
MVVLGGLDNTIGAVAGALALIVIPESARFLAEYRFLVYGLLLLVMLRFRPRGLLSAAS

Specific function: Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=293, Percent_Identity=37.542662116041, Blast_Score=170, Evalue=3e-43,
Organism=Escherichia coli, GI1789865, Length=304, Percent_Identity=37.171052631579, Blast_Score=164, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 64649; Mature: 64517

Theoretical pI: Translated: 10.48; Mature: 10.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAPLRSGTRRRGSMLDQLINGLVVGNLYALTAVGITQIYGVANVINFAHGSLYMVGAFV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
GWMAVTWLGLPLLPTLLLVLVASALLGLAVERVAIRPFAGSGRTVLLLTTIAAGLVLEQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHH
AQLIWGPETKAFHTPFADVRVRVGGGFLSSLDLVILAVGLTTALALWLFLKRSRLGWAVR
HHHHCCCCCCCCCCCHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
ATAQDREAALQMGVDVNQVSRVSFAMAGALAGVSGLLVGLYYHSVYPTMGFSASLKGFTA
ECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
ALLGGLGNIPGALVGAYLLGTAESLAVAWLGSTWRDLVGIGLLLGVLLFRPNGLFAAARA
HHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LLPEPTAGTFIPIGRPLPIPRWALPAAGAVALALPLVVRNGYWLQVLATAWIFGLLAISL
HCCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
NLIAGTAGQISLGHAGFLALGAYASAILTTRLQWPFLLSLAVAPVIAAAVGVVLCYPALR
HHHCCCCCCEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRGQYLAVATIGLGQGIALVALNWTALTRGPLGISNIAPPGLFGVEITSAAGFYWLTLTL
HCCCEEEEEEEECCCCEEEEEEEEHHEECCCCCCCCCCCCCCCCEEECCCCHHHHHHHHH
LLGGIWVAERLSGSYLGRALRAVREDEVAARAYGVGLERYKSIAFGLSAFIAGLAGVLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
HAYTYIAPDTFTHAMSLQVLTMVVLGGLDNTIGAVAGALALIVIPESARFLAEYRFLVYG
HHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEEEECCCHHHHHHHHHHHHH
LLLLVMLRFRPRGLLSAAS
HHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
AAPLRSGTRRRGSMLDQLINGLVVGNLYALTAVGITQIYGVANVINFAHGSLYMVGAFV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
GWMAVTWLGLPLLPTLLLVLVASALLGLAVERVAIRPFAGSGRTVLLLTTIAAGLVLEQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHH
AQLIWGPETKAFHTPFADVRVRVGGGFLSSLDLVILAVGLTTALALWLFLKRSRLGWAVR
HHHHCCCCCCCCCCCHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
ATAQDREAALQMGVDVNQVSRVSFAMAGALAGVSGLLVGLYYHSVYPTMGFSASLKGFTA
ECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
ALLGGLGNIPGALVGAYLLGTAESLAVAWLGSTWRDLVGIGLLLGVLLFRPNGLFAAARA
HHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LLPEPTAGTFIPIGRPLPIPRWALPAAGAVALALPLVVRNGYWLQVLATAWIFGLLAISL
HCCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
NLIAGTAGQISLGHAGFLALGAYASAILTTRLQWPFLLSLAVAPVIAAAVGVVLCYPALR
HHHCCCCCCEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRGQYLAVATIGLGQGIALVALNWTALTRGPLGISNIAPPGLFGVEITSAAGFYWLTLTL
HCCCEEEEEEEECCCCEEEEEEEEHHEECCCCCCCCCCCCCCCCEEECCCCHHHHHHHHH
LLGGIWVAERLSGSYLGRALRAVREDEVAARAYGVGLERYKSIAFGLSAFIAGLAGVLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
HAYTYIAPDTFTHAMSLQVLTMVVLGGLDNTIGAVAGALALIVIPESARFLAEYRFLVYG
HHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEEEECCCHHHHHHHHHHHHH
LLLLVMLRFRPRGLLSAAS
HHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2120183; 10984043; 2509433 [H]