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The map label for this gene is nucH [H]

Identifier: 51893483

GI number: 51893483

Start: 2533433

End: 2534281

Strand: Reverse

Name: nucH [H]

Synonym: STH2345

Alternate gene names: 51893483

Gene position: 2534281-2533433 (Counterclockwise)

Preceding gene: 51893489

Following gene: 51893482

Centisome position: 71.07

GC content: 73.85

Gene sequence:

>849_bases
GTGCAGGCGGGGGCGGGGCAGGACGGAACACGGACGGGGACGGAGGCGCCGGATACGACGGATGCGACGGTTGGGGCGGA
GCCGGCGTCGGGCGCGCCGCATGCGGACGCGGGGCAGGGAGCACCGAGTTCGGACGGGACGGCCGGCGCAGCCGCGGGCC
GTGAGGAGGGCGCGTCGGCGGGCGAGGCGCAGAGCCCGGCGCCGACCCCCGCGCAGACTCTGCAGGCTACGGTGCAGCGG
GTGGTGGACGGCGACACGGTGGACGTCCTGGTGGACGGACGGGAGGAGCGGGTGCGGCTGATCGGCGTGGACACGCCGGA
GGTCTACGGGAAGGCCGAGGCCTACGGCGCGGAGGCCTCCGCCTTCACCAAGCAGCGGCTGACCGGCCAGGAGGTGCGGC
TGGAGCTGGACGTGGAGGAGCGGGACCGGTACGGCCGGCTGCTGGCCTACGTCTGGATCGGTGACGAGATGTTCAACGAG
ACGCTGGTCCGGGAAGGCTACGCCCAGGTGATGACGGTTCCTCCCAACGTGAAGTATGCGGACCGGTTCGTCGCCCTCCA
GCGGGAGGCGCGGGAGCACGGCCGCGGGCTCTGGGGGTTGGAAGAGGCGTCCGGCTCCGGGGCCGGCGTCGCAGCCTCCG
GCGGAACGGCCTCCGGGGGCGCTGCGGGCGGCTCCGTCCTGCCGGTGAACGGCGACTGCGGCGGGCTGATCAAGGGCAAC
GTCTCCTCCAGCGGGGAGCTGATCTACCACGTGCCCGGCGGGCAGTTCTACGACCGGACCCGCGCGGAGGCCTGTTTCGC
CACGCCGGAAGAAGCGGAGGCCGCCGGCTACAGGAGGTCCAGGCGGTAG

Upstream 100 bases:

>100_bases
GTCCCGGGGCTGGGTCGCCCTGGCGGCGGTCGTCGTGATCGCGGCCGCGCTGAGCGGCCGGCCCGACAGCGGGGAAGGGC
AGAAGGCGCCGTCTTCCGCG

Downstream 100 bases:

>100_bases
GCCAAGGAACGCCGGCCCGCTGGCACCAACGTGCCATTTCGGGGCAACAATCCGTCGGGCCGTTGCAGGCGGCGAACCGT
ACGGTTTGAATGGAAATGGA

Product: micrococcal nuclease-like protein

Products: NA

Alternate protein names: TNase; Micrococcal nuclease; Staphylococcal nuclease [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MQAGAGQDGTRTGTEAPDTTDATVGAEPASGAPHADAGQGAPSSDGTAGAAAGREEGASAGEAQSPAPTPAQTLQATVQR
VVDGDTVDVLVDGREERVRLIGVDTPEVYGKAEAYGAEASAFTKQRLTGQEVRLELDVEERDRYGRLLAYVWIGDEMFNE
TLVREGYAQVMTVPPNVKYADRFVALQREAREHGRGLWGLEEASGSGAGVAASGGTASGGAAGGSVLPVNGDCGGLIKGN
VSSSGELIYHVPGGQFYDRTRAEACFATPEEAEAAGYRRSRR

Sequences:

>Translated_282_residues
MQAGAGQDGTRTGTEAPDTTDATVGAEPASGAPHADAGQGAPSSDGTAGAAAGREEGASAGEAQSPAPTPAQTLQATVQR
VVDGDTVDVLVDGREERVRLIGVDTPEVYGKAEAYGAEASAFTKQRLTGQEVRLELDVEERDRYGRLLAYVWIGDEMFNE
TLVREGYAQVMTVPPNVKYADRFVALQREAREHGRGLWGLEEASGSGAGVAASGGTASGGAAGGSVLPVNGDCGGLIKGN
VSSSGELIYHVPGGQFYDRTRAEACFATPEEAEAAGYRRSRR
>Mature_282_residues
MQAGAGQDGTRTGTEAPDTTDATVGAEPASGAPHADAGQGAPSSDGTAGAAAGREEGASAGEAQSPAPTPAQTLQATVQR
VVDGDTVDVLVDGREERVRLIGVDTPEVYGKAEAYGAEASAFTKQRLTGQEVRLELDVEERDRYGRLLAYVWIGDEMFNE
TLVREGYAQVMTVPPNVKYADRFVALQREAREHGRGLWGLEEASGSGAGVAASGGTASGGAAGGSVLPVNGDCGGLIKGN
VSSSGELIYHVPGGQFYDRTRAEACFATPEEAEAAGYRRSRR

Specific function: Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5'-position of the phosphodiester bond [H]

COG id: COG1525

COG function: function code L; Micrococcal nuclease (thermonuclease) homologs

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thermonuclease family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016071
- InterPro:   IPR006021
- InterPro:   IPR002071 [H]

Pfam domain/function: PF00565 SNase [H]

EC number: =3.1.31.1 [H]

Molecular weight: Translated: 29120; Mature: 29120

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: PS01123 TNASE_1 ; PS01284 TNASE_2 ; PS50830 TNASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAGAGQDGTRTGTEAPDTTDATVGAEPASGAPHADAGQGAPSSDGTAGAAAGREEGASA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GEAQSPAPTPAQTLQATVQRVVDGDTVDVLVDGREERVRLIGVDTPEVYGKAEAYGAEAS
CCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCCHHHHCCHHHCCCHHH
AFTKQRLTGQEVRLELDVEERDRYGRLLAYVWIGDEMFNETLVREGYAQVMTVPPNVKYA
HHHHHHCCCCEEEEEECHHHHHCCCEEEEEEEECHHHHHHHHHHCCCCEEEECCCCCHHH
DRFVALQREAREHGRGLWGLEEASGSGAGVAASGGTASGGAAGGSVLPVNGDCGGLIKGN
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEECCCCCCEEECC
VSSSGELIYHVPGGQFYDRTRAEACFATPEEAEAAGYRRSRR
CCCCCCEEEECCCCCHHHHHHHHHHCCCCCHHHHHCHHHCCC
>Mature Secondary Structure
MQAGAGQDGTRTGTEAPDTTDATVGAEPASGAPHADAGQGAPSSDGTAGAAAGREEGASA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GEAQSPAPTPAQTLQATVQRVVDGDTVDVLVDGREERVRLIGVDTPEVYGKAEAYGAEAS
CCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCCHHHHCCHHHCCCHHH
AFTKQRLTGQEVRLELDVEERDRYGRLLAYVWIGDEMFNETLVREGYAQVMTVPPNVKYA
HHHHHHCCCCEEEEEECHHHHHCCCEEEEEEEECHHHHHHHHHHCCCCEEEECCCCCHHH
DRFVALQREAREHGRGLWGLEEASGSGAGVAASGGTASGGAAGGSVLPVNGDCGGLIKGN
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEECCCCCCEEECC
VSSSGELIYHVPGGQFYDRTRAEACFATPEEAEAAGYRRSRR
CCCCCCEEEECCCCCHHHHHHHHHHCCCCCHHHHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8045422 [H]