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The map label for this gene is rbsR [H]

Identifier: 51893481

GI number: 51893481

Start: 2530900

End: 2531910

Strand: Reverse

Name: rbsR [H]

Synonym: STH2343

Alternate gene names: 51893481

Gene position: 2531910-2530900 (Counterclockwise)

Preceding gene: 51893482

Following gene: 51893480

Centisome position: 71.0

GC content: 64.19

Gene sequence:

>1011_bases
GTGAAGAAGCGGAGCGTCTCCATCAAGGAGATCTCGGAACTGGCCGGCGTCTCGGTGGCGACGGTTTCAAGGGTCATCAA
CCGGAACGGCCGGTACTCCAAAGAGACGGAGCAGCGAGTCCTGCAGATCATAGAGGAATACGGGTATCAGCCCGATCTGG
TGGCGCGGGGGCTGCGCACCCGGAAACTCCAGGTCGTCGGGGTGATCGTGCCCGACATCACCAACGAGTTCTTCGCCCGG
GTCACCCAGGAACTGCAGAACAACCTGTTTGCGCTCGGCTACTCGACCATCATCTGCAACACCAATGAGGAGTACGAGAA
GGAAAAGCGTTACCTCGCCATGCTCCGGGCCCAGAAGGTCAGCGGGCTGATCTACATCTCCGGTCTCCGCACCGAAGGGC
AGCCGTCGCTCCTGGTGCCGACGGTGTACATCGACCGCAAGCCGCCCCGGACCAGCGAAACCGCCGAGCTCGTGTTCATC
GAGAGCGCCAACGAGGAGGGCGGGTACCTGGCCACCCGGTCCCTGCTGGACAGCGGATGCCGGCGTGTCGGTCTCATCAC
GTACCGCCCGGACATCTCCTCTCACGGTGACCGCCTGCGCGGGTACCGGAAGGCCCTGGAAGAACGGGGGCTGCCTTTCG
ACCAGGACCTGGTGGTGCAGGTCTCCCGGGTGAGCATGTCCAGCGGCTTCGAGGCGGCCTTGCAGCTGATGCGCGCTCAC
CCCGAGATCGATGGCTTCTTCTGCACGGCCGATCTGCTGGCCTACGGCGTGCTGAGCTGCCTGTCCGGTCCGGCCGGGAT
GGCAGCGGGCAGACGCATCCGGTTGGTGGGGTTTGACGATCTTTCGTTCTCGGGCACCGAGGCCTTCTCCCTTTCCAGCG
TCCGGCAGTCGGTGGAGGAGTTCGGCAGGCTGGGCGCCTACGCCGTGGTGCAGATGATCGAAGGAAAGCCACTGGAGCGC
AAGCACTATCGGCTTCCCGTGGAACTGGTCCTCCGCAATACGACCCGGTGA

Upstream 100 bases:

>100_bases
TCGCCTATTGACAGGTTGAAGGATTGGCGGATACGATGTGAAAGGATGGTGTGGGTAAACCTTTTCCCATCGCAGTCGGT
CGATCGGAGGGGAGTGACCC

Downstream 100 bases:

>100_bases
CCTTTCTTTTTGCGTGAGTAAACGTTTACCATCGAAGAGTAAACGTTTACGCTTCTGCCTGATTCAGAGCCCGTGCCTCG
GCAAGGGTTTTGAATACACA

Product: LacI family transcriptional repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MKKRSVSIKEISELAGVSVATVSRVINRNGRYSKETEQRVLQIIEEYGYQPDLVARGLRTRKLQVVGVIVPDITNEFFAR
VTQELQNNLFALGYSTIICNTNEEYEKEKRYLAMLRAQKVSGLIYISGLRTEGQPSLLVPTVYIDRKPPRTSETAELVFI
ESANEEGGYLATRSLLDSGCRRVGLITYRPDISSHGDRLRGYRKALEERGLPFDQDLVVQVSRVSMSSGFEAALQLMRAH
PEIDGFFCTADLLAYGVLSCLSGPAGMAAGRRIRLVGFDDLSFSGTEAFSLSSVRQSVEEFGRLGAYAVVQMIEGKPLER
KHYRLPVELVLRNTTR

Sequences:

>Translated_336_residues
MKKRSVSIKEISELAGVSVATVSRVINRNGRYSKETEQRVLQIIEEYGYQPDLVARGLRTRKLQVVGVIVPDITNEFFAR
VTQELQNNLFALGYSTIICNTNEEYEKEKRYLAMLRAQKVSGLIYISGLRTEGQPSLLVPTVYIDRKPPRTSETAELVFI
ESANEEGGYLATRSLLDSGCRRVGLITYRPDISSHGDRLRGYRKALEERGLPFDQDLVVQVSRVSMSSGFEAALQLMRAH
PEIDGFFCTADLLAYGVLSCLSGPAGMAAGRRIRLVGFDDLSFSGTEAFSLSSVRQSVEEFGRLGAYAVVQMIEGKPLER
KHYRLPVELVLRNTTR
>Mature_336_residues
MKKRSVSIKEISELAGVSVATVSRVINRNGRYSKETEQRVLQIIEEYGYQPDLVARGLRTRKLQVVGVIVPDITNEFFAR
VTQELQNNLFALGYSTIICNTNEEYEKEKRYLAMLRAQKVSGLIYISGLRTEGQPSLLVPTVYIDRKPPRTSETAELVFI
ESANEEGGYLATRSLLDSGCRRVGLITYRPDISSHGDRLRGYRKALEERGLPFDQDLVVQVSRVSMSSGFEAALQLMRAH
PEIDGFFCTADLLAYGVLSCLSGPAGMAAGRRIRLVGFDDLSFSGTEAFSLSSVRQSVEEFGRLGAYAVVQMIEGKPLER
KHYRLPVELVLRNTTR

Specific function: Transcriptional repressor for the ribose rbsDACBK operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787948, Length=301, Percent_Identity=28.2392026578073, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1790194, Length=328, Percent_Identity=29.5731707317073, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1789202, Length=316, Percent_Identity=28.1645569620253, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788474, Length=340, Percent_Identity=26.7647058823529, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790369, Length=353, Percent_Identity=22.9461756373938, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789068, Length=337, Percent_Identity=25.5192878338279, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1787906, Length=342, Percent_Identity=25.4385964912281, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1790715, Length=342, Percent_Identity=26.3157894736842, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI48994940, Length=335, Percent_Identity=26.5671641791045, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787580, Length=322, Percent_Identity=23.2919254658385, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1786540, Length=338, Percent_Identity=24.8520710059172, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786268, Length=265, Percent_Identity=25.2830188679245, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1790689, Length=263, Percent_Identity=23.9543726235741, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37587; Mature: 37587

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRSVSIKEISELAGVSVATVSRVINRNGRYSKETEQRVLQIIEEYGYQPDLVARGLRT
CCCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCHH
RKLQVVGVIVPDITNEFFARVTQELQNNLFALGYSTIICNTNEEYEKEKRYLAMLRAQKV
CEEEEEEEECCCHHHHHHHHHHHHHHCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHH
SGLIYISGLRTEGQPSLLVPTVYIDRKPPRTSETAELVFIESANEEGGYLATRSLLDSGC
CCEEEEEECCCCCCCCEEEEEEEECCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHCC
RRVGLITYRPDISSHGDRLRGYRKALEERGLPFDQDLVVQVSRVSMSSGFEAALQLMRAH
HHEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHC
PEIDGFFCTADLLAYGVLSCLSGPAGMAAGRRIRLVGFDDLSFSGTEAFSLSSVRQSVEE
CCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHH
FGRLGAYAVVQMIEGKPLERKHYRLPVELVLRNTTR
HHHHHHHHHHHHHCCCCCCCHHCCCCHHEEECCCCC
>Mature Secondary Structure
MKKRSVSIKEISELAGVSVATVSRVINRNGRYSKETEQRVLQIIEEYGYQPDLVARGLRT
CCCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCHH
RKLQVVGVIVPDITNEFFARVTQELQNNLFALGYSTIICNTNEEYEKEKRYLAMLRAQKV
CEEEEEEEECCCHHHHHHHHHHHHHHCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHH
SGLIYISGLRTEGQPSLLVPTVYIDRKPPRTSETAELVFIESANEEGGYLATRSLLDSGC
CCEEEEEECCCCCCCCEEEEEEEECCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHCC
RRVGLITYRPDISSHGDRLRGYRKALEERGLPFDQDLVVQVSRVSMSSGFEAALQLMRAH
HHEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHC
PEIDGFFCTADLLAYGVLSCLSGPAGMAAGRRIRLVGFDDLSFSGTEAFSLSSVRQSVEE
CCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHH
FGRLGAYAVVQMIEGKPLERKHYRLPVELVLRNTTR
HHHHHHHHHHHHHCCCCCCCHHCCCCHHEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]