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The map label for this gene is spoVD [H]

Identifier: 51893129

GI number: 51893129

Start: 2131934

End: 2133586

Strand: Reverse

Name: spoVD [H]

Synonym: STH1991

Alternate gene names: 51893129

Gene position: 2133586-2131934 (Counterclockwise)

Preceding gene: 51893130

Following gene: 51893125

Centisome position: 59.83

GC content: 74.65

Gene sequence:

>1653_bases
GTGCTGAGCCTCGCGGCCTGGGTCTGCCTGGCCCTCCTGGGGGTACGGCTGTTCCAGCTCCAGATCCTGCGCGGGCCGGC
CCTGACCCGCCAGGTGTTCGGCCAGCGCACCGAGCGGCTGCCCCTTGAGATGCGGCGGGGCATGATCTACGACCGCTATG
GCGTTCCGCTCACGGACCCGCAGTCCACGTGGGGGCTGGCCGTCTTTCCCCGCCTGTTCGGCGACCCGGCCGTGGCGGCG
CCGGTGCTGGCGGAGGCCCTGGGCGAAGAGCGGGCCGCGGTGGTGCTGGACTACGTGCAGCGGCACCACGAGGCGGGATG
GGTGATCGAAGGGCTGTCGGACGAGGCGGCGCAGCAGGTGCAGGACTACGCCGCGGCGGGGCTGCTGCCCGGCGTGGCGG
TGGGCCCCACGGGCTGGCGCTACGGCCCGGGCTCTCTGGCCCGCCACCTGGTGGGTTTCGCCAACGCCTCGGGGGGGTGG
ACGGGGCTGGAGCTGGCCTACGACTCCGTCTTGCGGGGGGAGAACGTGCCGCACCTGGTGGCCAGCTACCACGGGCGGGG
CGGCCCCCTCGGGGACGAACCGCTGCAGGTGCTGCAGCCCCGCGACCCCGCCGGCAAGGAGCCCTACGACGTGCACACCA
CCCTCGACGCCCGGATCCAGGCCGCCGTGGAGCGGGAGATGGACCGGACCGCCCACCCGGACGGCGGCCCCCTGCGGGCG
GCGGTGGTGGTGGTGGACCCGGCCACGGGGGAGCTGCTGGCCCTGGCGTCGCGCCCCAACTTCGACCAGGCCCGCTACGC
CACCGAGGACCAGCTGCGCAACCGGGCCCTCACCCCCTATGAGACCGGTTCGGTCTTCAAGCCGATCGTGGCGGCGGCGG
CGCTGGAAGCCGGCGCCGTCGTCCCCCACGAGCGCATCGAGTGCAGCGGGACCTATCAACTGGGCGACCGCATCTTCCGG
GACGTGGCCGGTACGGTGACGGGGCCGGTGACGTTACGGGAGGCGCTCGCCCGGTCGTGCAACACGGCCTTCATCCGGAT
CGGCTACGAGCGGCTGGGCGCAGACCGGCTGCTGGAGGCCGCCCGGCGGTTCGGGCTGGACGAGCCGACCGGCGCCCTCC
CGTCCGGTTTCGAGACGGTGGCGCCGCTGCCGGAGCCCCGCTACGGCGGCGACGTCGCCCAGCTCAGCTTCGGCCAGGGC
GGCCTGCGGGCCAGCCCCCTGCAGGTCGCGCGGGCCTACACCGCCATTGCCAACGGCGGGGTGCTGCATCCGATCCGCCT
GGTGACCAGCGTGAGGAGGAGCGACGGCGAGGTGGTCTTCCGCCCGCGGACGGAACCCTCCCGGCGGGTGATGAGCCGCG
AGACCGCCGCCGAACTGCGGCAGGCGCTCCTGCTGGCGGTGGTGCCCGGCGGCGGCGGGACCGGGGAGGCGGCCTGGGTG
GACGACGCGGGCGCCGCCGGCAAGTCCGGTTCAGCCGACACCGTGCTGGACGGCCGGCCGGCCACCCATGCCTGGTTCGC
CGGCTGGTTCCCAGCCCGGCAGCCGCAGTACGTCATGGTGGTCTTCATCGAGGACGGGCGCGCGGGGGGAGCCCACGCGG
CGCCGCTCTTCCGGCGGATTGCCGAGGCGATCCTCTCGCTGGACGAAGGATGA

Upstream 100 bases:

>100_bases
CCGGACCGCCGGGGACATAATGTATAGGGAAGAACACCTCGGGAGATCCTCTCCAACGAGGTGTTCTTTTGTGCGTATTC
GGATGGTTCGCCGGATGTTC

Downstream 100 bases:

>100_bases
AAGGCGGCGCCCCCCTTGGGCGGGAGGCGCCGCCTGCCGTCCGGCTACAGGCTGACGGTCATGCCGCCGTCGACGTGGAT
GGCCGAGCCGGTGATGTAGC

Product: stage V sporulation protein D

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 550; Mature: 550

Protein sequence:

>550_residues
MLSLAAWVCLALLGVRLFQLQILRGPALTRQVFGQRTERLPLEMRRGMIYDRYGVPLTDPQSTWGLAVFPRLFGDPAVAA
PVLAEALGEERAAVVLDYVQRHHEAGWVIEGLSDEAAQQVQDYAAAGLLPGVAVGPTGWRYGPGSLARHLVGFANASGGW
TGLELAYDSVLRGENVPHLVASYHGRGGPLGDEPLQVLQPRDPAGKEPYDVHTTLDARIQAAVEREMDRTAHPDGGPLRA
AVVVVDPATGELLALASRPNFDQARYATEDQLRNRALTPYETGSVFKPIVAAAALEAGAVVPHERIECSGTYQLGDRIFR
DVAGTVTGPVTLREALARSCNTAFIRIGYERLGADRLLEAARRFGLDEPTGALPSGFETVAPLPEPRYGGDVAQLSFGQG
GLRASPLQVARAYTAIANGGVLHPIRLVTSVRRSDGEVVFRPRTEPSRRVMSRETAAELRQALLLAVVPGGGGTGEAAWV
DDAGAAGKSGSADTVLDGRPATHAWFAGWFPARQPQYVMVVFIEDGRAGGAHAAPLFRRIAEAILSLDEG

Sequences:

>Translated_550_residues
MLSLAAWVCLALLGVRLFQLQILRGPALTRQVFGQRTERLPLEMRRGMIYDRYGVPLTDPQSTWGLAVFPRLFGDPAVAA
PVLAEALGEERAAVVLDYVQRHHEAGWVIEGLSDEAAQQVQDYAAAGLLPGVAVGPTGWRYGPGSLARHLVGFANASGGW
TGLELAYDSVLRGENVPHLVASYHGRGGPLGDEPLQVLQPRDPAGKEPYDVHTTLDARIQAAVEREMDRTAHPDGGPLRA
AVVVVDPATGELLALASRPNFDQARYATEDQLRNRALTPYETGSVFKPIVAAAALEAGAVVPHERIECSGTYQLGDRIFR
DVAGTVTGPVTLREALARSCNTAFIRIGYERLGADRLLEAARRFGLDEPTGALPSGFETVAPLPEPRYGGDVAQLSFGQG
GLRASPLQVARAYTAIANGGVLHPIRLVTSVRRSDGEVVFRPRTEPSRRVMSRETAAELRQALLLAVVPGGGGTGEAAWV
DDAGAAGKSGSADTVLDGRPATHAWFAGWFPARQPQYVMVVFIEDGRAGGAHAAPLFRRIAEAILSLDEG
>Mature_550_residues
MLSLAAWVCLALLGVRLFQLQILRGPALTRQVFGQRTERLPLEMRRGMIYDRYGVPLTDPQSTWGLAVFPRLFGDPAVAA
PVLAEALGEERAAVVLDYVQRHHEAGWVIEGLSDEAAQQVQDYAAAGLLPGVAVGPTGWRYGPGSLARHLVGFANASGGW
TGLELAYDSVLRGENVPHLVASYHGRGGPLGDEPLQVLQPRDPAGKEPYDVHTTLDARIQAAVEREMDRTAHPDGGPLRA
AVVVVDPATGELLALASRPNFDQARYATEDQLRNRALTPYETGSVFKPIVAAAALEAGAVVPHERIECSGTYQLGDRIFR
DVAGTVTGPVTLREALARSCNTAFIRIGYERLGADRLLEAARRFGLDEPTGALPSGFETVAPLPEPRYGGDVAQLSFGQG
GLRASPLQVARAYTAIANGGVLHPIRLVTSVRRSDGEVVFRPRTEPSRRVMSRETAAELRQALLLAVVPGGGGTGEAAWV
DDAGAAGKSGSADTVLDGRPATHAWFAGWFPARQPQYVMVVFIEDGRAGGAHAAPLFRRIAEAILSLDEG

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=567, Percent_Identity=28.042328042328, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI1786854, Length=614, Percent_Identity=25.4071661237785, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 58750; Mature: 58750

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS00024 HEMOPEXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLAAWVCLALLGVRLFQLQILRGPALTRQVFGQRTERLPLEMRRGMIYDRYGVPLTDP
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHCCEEEECCCCCCCCC
QSTWGLAVFPRLFGDPAVAAPVLAEALGEERAAVVLDYVQRHHEAGWVIEGLSDEAAQQV
CCCCCHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEECCCHHHHHHH
QDYAAAGLLPGVAVGPTGWRYGPGSLARHLVGFANASGGWTGLELAYDSVLRGENVPHLV
HHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHH
ASYHGRGGPLGDEPLQVLQPRDPAGKEPYDVHTTLDARIQAAVEREMDRTAHPDGGPLRA
HHCCCCCCCCCCCCHHHCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHCCCCCCCCEEE
AVVVVDPATGELLALASRPNFDQARYATEDQLRNRALTPYETGSVFKPIVAAAALEAGAV
EEEEEECCCCCEEEEECCCCCCHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCC
VPHERIECSGTYQLGDRIFRDVAGTVTGPVTLREALARSCNTAFIRIGYERLGADRLLEA
CCHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECHHHHCHHHHHHH
ARRFGLDEPTGALPSGFETVAPLPEPRYGGDVAQLSFGQGGLRASPLQVARAYTAIANGG
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCC
VLHPIRLVTSVRRSDGEVVFRPRTEPSRRVMSRETAAELRQALLLAVVPGGGGTGEAAWV
CCHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCEEE
DDAGAAGKSGSADTVLDGRPATHAWFAGWFPARQPQYVMVVFIEDGRAGGAHAAPLFRRI
CCCCCCCCCCCCCCEECCCCCCCHHHHCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHH
AEAILSLDEG
HHHHHHCCCC
>Mature Secondary Structure
MLSLAAWVCLALLGVRLFQLQILRGPALTRQVFGQRTERLPLEMRRGMIYDRYGVPLTDP
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHCCEEEECCCCCCCCC
QSTWGLAVFPRLFGDPAVAAPVLAEALGEERAAVVLDYVQRHHEAGWVIEGLSDEAAQQV
CCCCCHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEECCCHHHHHHH
QDYAAAGLLPGVAVGPTGWRYGPGSLARHLVGFANASGGWTGLELAYDSVLRGENVPHLV
HHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHH
ASYHGRGGPLGDEPLQVLQPRDPAGKEPYDVHTTLDARIQAAVEREMDRTAHPDGGPLRA
HHCCCCCCCCCCCCHHHCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHCCCCCCCCEEE
AVVVVDPATGELLALASRPNFDQARYATEDQLRNRALTPYETGSVFKPIVAAAALEAGAV
EEEEEECCCCCEEEEECCCCCCHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCC
VPHERIECSGTYQLGDRIFRDVAGTVTGPVTLREALARSCNTAFIRIGYERLGADRLLEA
CCHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECHHHHCHHHHHHH
ARRFGLDEPTGALPSGFETVAPLPEPRYGGDVAQLSFGQGGLRASPLQVARAYTAIANGG
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCC
VLHPIRLVTSVRRSDGEVVFRPRTEPSRRVMSRETAAELRQALLLAVVPGGGGTGEAAWV
CCHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCEEE
DDAGAAGKSGSADTVLDGRPATHAWFAGWFPARQPQYVMVVFIEDGRAGGAHAAPLFRRI
CCCCCCCCCCCCCCEECCCCCCCHHHHCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHH
AEAILSLDEG
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]