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The map label for this gene is gufA [H]

Identifier: 51893119

GI number: 51893119

Start: 2118600

End: 2119415

Strand: Reverse

Name: gufA [H]

Synonym: STH1981

Alternate gene names: 51893119

Gene position: 2119415-2118600 (Counterclockwise)

Preceding gene: 51893122

Following gene: 51893118

Centisome position: 59.43

GC content: 68.5

Gene sequence:

>816_bases
GTGGTAAGATGCATGCGGGAGGTCGGTAGACCCATGGACTTGGCTGCGAACGCGAACACGATCCTGCTCGGCCTGTTGGC
CAGCCTGCTGGCCGGCCTCGCGACGGTGATCGGCGCACTCCCGACACTGTTCACCCGATCGATCTCACCGCGCATCCAGG
ACGGCCTGCTGGGCATGGCCGCGGGGGTCATGCTGGCCGCCACGATTTTCAGCCTGCTGATTCCGGCGATGGAGTACGGC
GGCGGAGGGCTGCGGGGCGCCCTGGTCGCGGCCGTGGGCCTCTTCGTGGGCGGCGCCTTCCTGGACCTGATCGACCGGTA
CTCGCCGCACCAGCACTTCATCAAGGGGCCCGAAGGCGGCGGGGCGACCTCGTCGCTGCAGCGCATCTGGCTGTTCATCA
TCGCGATTACGATCCACAACTTCCCGGAGGGACTGGCCGTGGGCGTGGGCGTCGGCAGCGGCGACCTGGGCAGCGGCCTC
AGCCTGGCGATGGGCATCGGGCTGCAGAATATCCCCGAGGGCATGGCGGTGGCCCTGGCGCTGCTGTCGGAGCGCTACGC
CCTGCGCGAGGTGTTCCTGATCACCCTGCTGACCGGCCTGGTCGAGCCGGTGGGCGGGCTGCTGGGCGTCGCGGCGGTCA
CCCTGATGCATCCGATCCTGCCGTGGGCGCTGGCCTTCGCCGGCGGGGCGATGCTGTTCGTCATCAGCGACGAGATCATC
CCCGAGACCCACGAGCGGGGCAACGAGCGCACCGCGACGTACATGTTGCTCCTGGGGTTCGTCATCATGATGCTGCTGGA
CACGACGCTGGGTTAG

Upstream 100 bases:

>100_bases
ACGGCAATCTCCATCTGCTTCACTCCCTCGCCCCATCCTATGCCCGGAAGGCGGAAGGGGTCCGGGGAGGGGAGGCGGCG
GTTCCCGATGGCCCGTCAAC

Downstream 100 bases:

>100_bases
TCTGTAGGCGCGATTCGGGCCGCCTCCCGTGCGGGAGGCGGCCCGTGTCGGTGTGCCCGGCATGGGCGCTGACTTGGCGG
TGAAAGTCCGCTACGGGCGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MVRCMREVGRPMDLAANANTILLGLLASLLAGLATVIGALPTLFTRSISPRIQDGLLGMAAGVMLAATIFSLLIPAMEYG
GGGLRGALVAAVGLFVGGAFLDLIDRYSPHQHFIKGPEGGGATSSLQRIWLFIIAITIHNFPEGLAVGVGVGSGDLGSGL
SLAMGIGLQNIPEGMAVALALLSERYALREVFLITLLTGLVEPVGGLLGVAAVTLMHPILPWALAFAGGAMLFVISDEII
PETHERGNERTATYMLLLGFVIMMLLDTTLG

Sequences:

>Translated_271_residues
MVRCMREVGRPMDLAANANTILLGLLASLLAGLATVIGALPTLFTRSISPRIQDGLLGMAAGVMLAATIFSLLIPAMEYG
GGGLRGALVAAVGLFVGGAFLDLIDRYSPHQHFIKGPEGGGATSSLQRIWLFIIAITIHNFPEGLAVGVGVGSGDLGSGL
SLAMGIGLQNIPEGMAVALALLSERYALREVFLITLLTGLVEPVGGLLGVAAVTLMHPILPWALAFAGGAMLFVISDEII
PETHERGNERTATYMLLLGFVIMMLLDTTLG
>Mature_271_residues
MVRCMREVGRPMDLAANANTILLGLLASLLAGLATVIGALPTLFTRSISPRIQDGLLGMAAGVMLAATIFSLLIPAMEYG
GGGLRGALVAAVGLFVGGAFLDLIDRYSPHQHFIKGPEGGGATSSLQRIWLFIIAITIHNFPEGLAVGVGVGSGDLGSGL
SLAMGIGLQNIPEGMAVALALLSERYALREVFLITLLTGLVEPVGGLLGVAAVTLMHPILPWALAFAGGAMLFVISDEII
PETHERGNERTATYMLLLGFVIMMLLDTTLG

Specific function: Mediates Zinc Uptake. May Also Transport Other Divalent Cations Such As Copper And Cadmium Ions. [C]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI229577422, Length=154, Percent_Identity=51.9480519480519, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI229577418, Length=154, Percent_Identity=51.9480519480519, Blast_Score=146, Evalue=2e-35,
Organism=Escherichia coli, GI1789419, Length=250, Percent_Identity=31.2, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17507805, Length=154, Percent_Identity=48.7012987012987, Blast_Score=145, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24652846, Length=155, Percent_Identity=47.0967741935484, Blast_Score=141, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 28175; Mature: 28175

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRCMREVGRPMDLAANANTILLGLLASLLAGLATVIGALPTLFTRSISPRIQDGLLGMA
CCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AGVMLAATIFSLLIPAMEYGGGGLRGALVAAVGLFVGGAFLDLIDRYSPHQHFIKGPEGG
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCC
GATSSLQRIWLFIIAITIHNFPEGLAVGVGVGSGDLGSGLSLAMGIGLQNIPEGMAVALA
CHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHCCHHHCCHHHHHHHH
LLSERYALREVFLITLLTGLVEPVGGLLGVAAVTLMHPILPWALAFAGGAMLFVISDEII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHC
PETHERGNERTATYMLLLGFVIMMLLDTTLG
CCHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVRCMREVGRPMDLAANANTILLGLLASLLAGLATVIGALPTLFTRSISPRIQDGLLGMA
CCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AGVMLAATIFSLLIPAMEYGGGGLRGALVAAVGLFVGGAFLDLIDRYSPHQHFIKGPEGG
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCC
GATSSLQRIWLFIIAITIHNFPEGLAVGVGVGSGDLGSGLSLAMGIGLQNIPEGMAVALA
CHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHCCHHHCCHHHHHHHH
LLSERYALREVFLITLLTGLVEPVGGLLGVAAVTLMHPILPWALAFAGGAMLFVISDEII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHC
PETHERGNERTATYMLLLGFVIMMLLDTTLG
CCHHHCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934835 [H]