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The map label for this gene is aroC

Identifier: 51893088

GI number: 51893088

Start: 2090885

End: 2092060

Strand: Reverse

Name: aroC

Synonym: STH1950

Alternate gene names: 51893088

Gene position: 2092060-2090885 (Counterclockwise)

Preceding gene: 51893089

Following gene: 51893087

Centisome position: 58.66

GC content: 74.06

Gene sequence:

>1176_bases
TTGCGGTACCTGACAGCCGGCGAGTCGCACGGGCGGGCGCTGGTGACCATCGTCGAGGGGCTGCCCGCCGGCGTGCCGGT
GGACCTGGCGGCCATCGACCGCGACCTCGCCCGGCGGCAGTCCGGCTACGGGCGGGGCGGGCGGATGAAGATCGAGCAGG
ACCGGGTGCAGGTGCTGTCGGGCATCCGGCACGGCAAGACCCTGGGCAGCCCGGTCGCGCTGCTGGTGGAGAACCGGGAC
TGGCTCAACTGGACCGAAGTGATGTCGCCTGCGCCGCTGGAGGCCTACACCGACCCGCGGGCGGCGCAGAAGGTGCGGAC
GCGCCCCCGGCCGGGCCACGCGGACCTGGCGGGGGCCCTGAAGTACGATCACGCCGACCTGCGCAACGTGCTGGAGCGGG
CCTCGGCCCGGGAGACCGCGGCGCGGGTGGCGGCGGGGTCGCTGGCCAAGCAGTACCTGGCGCCGTTCGGCATCCGGGTG
GCCGGGTACGTGCGGTCCATCGGCCCCGTGGAGGCCCAGCCCCCGGCCGGGCTGGACCTGGACGGGATCGTCGCCCGGGC
GGAGGCGAGCCCCGTGCGCTGCCCCGACCCCGCGGCGTCGGCCCGGATGGTGGAGGAGATCGACGCGGCGAAGCGGGACG
GCGACTCGCTGGGCGGCGTCGTGGAGGTGGTGGCCGCGGGGCTCCCGCCGGGCCTGGGCAGCCACGTGCACTGGGACCGG
AAGCTGGACGGCGCCCTCGGGGCGGCCTTGCTCTCCATTCAGGCCGCCAAGGGCGTGGAGATCGGCGACGGGTTTCTGGG
CGCCCGGCGGCGGGGCTCGGAGGTGCACGACGAGATCGGCTGGAGTCCGGACAGGGGCTACTTCCGTTACACGAACCGGG
CGGGCGGGCTGGAGGGCGGTATGACCAACGGGATGGACCTGGTGGTCCGGGTTGCCTTCAAGCCCATCGCCACGCTGTAC
AAGCCCCTGCGCTCCGTGGAGATCGATACGCACGTCGAGGCCGCGGCGGGCATCGAGCGGTCCGACGTCTGTGCCGTGCC
CGCCGCGGCGGTGATCGCGGAGTGCGTCACCGCCTTCGAGCTGGCCCGTTTCGTGGCCGAGAAGTTCGGCGGCGACTCGC
TGGAGGAGGCCCTGCGCAACTTCCGCGGGTACCTGGAACAGATCGCCCGGCGCTGA

Upstream 100 bases:

>100_bases
CCGTTCCTCGCCGCGGGCGGCCTGATCACCATCCTGTGGGGAAGCCAGATCTGGAACTGGTACGCGGGATGACGCATAGG
AAGGGGGCGGTCCCGGAGTG

Downstream 100 bases:

>100_bases
CGGGCCGGGGGGCGCCCGCGGACGGGCTCGCGGGAGCGCGCGGCGGCAGGGGGGCGGTGCGGTGAACATCGTTCTCGTGG
GACTCATGGGATCCGGCAAG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MRYLTAGESHGRALVTIVEGLPAGVPVDLAAIDRDLARRQSGYGRGGRMKIEQDRVQVLSGIRHGKTLGSPVALLVENRD
WLNWTEVMSPAPLEAYTDPRAAQKVRTRPRPGHADLAGALKYDHADLRNVLERASARETAARVAAGSLAKQYLAPFGIRV
AGYVRSIGPVEAQPPAGLDLDGIVARAEASPVRCPDPAASARMVEEIDAAKRDGDSLGGVVEVVAAGLPPGLGSHVHWDR
KLDGALGAALLSIQAAKGVEIGDGFLGARRRGSEVHDEIGWSPDRGYFRYTNRAGGLEGGMTNGMDLVVRVAFKPIATLY
KPLRSVEIDTHVEAAAGIERSDVCAVPAAAVIAECVTAFELARFVAEKFGGDSLEEALRNFRGYLEQIARR

Sequences:

>Translated_391_residues
MRYLTAGESHGRALVTIVEGLPAGVPVDLAAIDRDLARRQSGYGRGGRMKIEQDRVQVLSGIRHGKTLGSPVALLVENRD
WLNWTEVMSPAPLEAYTDPRAAQKVRTRPRPGHADLAGALKYDHADLRNVLERASARETAARVAAGSLAKQYLAPFGIRV
AGYVRSIGPVEAQPPAGLDLDGIVARAEASPVRCPDPAASARMVEEIDAAKRDGDSLGGVVEVVAAGLPPGLGSHVHWDR
KLDGALGAALLSIQAAKGVEIGDGFLGARRRGSEVHDEIGWSPDRGYFRYTNRAGGLEGGMTNGMDLVVRVAFKPIATLY
KPLRSVEIDTHVEAAAGIERSDVCAVPAAAVIAECVTAFELARFVAEKFGGDSLEEALRNFRGYLEQIARR
>Mature_391_residues
MRYLTAGESHGRALVTIVEGLPAGVPVDLAAIDRDLARRQSGYGRGGRMKIEQDRVQVLSGIRHGKTLGSPVALLVENRD
WLNWTEVMSPAPLEAYTDPRAAQKVRTRPRPGHADLAGALKYDHADLRNVLERASARETAARVAAGSLAKQYLAPFGIRV
AGYVRSIGPVEAQPPAGLDLDGIVARAEASPVRCPDPAASARMVEEIDAAKRDGDSLGGVVEVVAAGLPPGLGSHVHWDR
KLDGALGAALLSIQAAKGVEIGDGFLGARRRGSEVHDEIGWSPDRGYFRYTNRAGGLEGGMTNGMDLVVRVAFKPIATLY
KPLRSVEIDTHVEAAAGIERSDVCAVPAAAVIAECVTAFELARFVAEKFGGDSLEEALRNFRGYLEQIARR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=363, Percent_Identity=39.6694214876033, Blast_Score=180, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6321290, Length=371, Percent_Identity=34.5013477088949, Blast_Score=192, Evalue=8e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_SYMTH (Q67N08)

Other databases:

- EMBL:   AP006840
- RefSeq:   YP_075779.1
- ProteinModelPortal:   Q67N08
- SMR:   Q67N08
- GeneID:   2980926
- GenomeReviews:   AP006840_GR
- KEGG:   sth:STH1950
- NMPDR:   fig|292459.1.peg.1880
- HOGENOM:   HBG292336
- OMA:   GSEAHDE
- ProtClustDB:   PRK05382
- BioCyc:   STHE292459:STH1950-MONOMER
- BRENDA:   4.2.3.5
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 41733; Mature: 41733

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYLTAGESHGRALVTIVEGLPAGVPVDLAAIDRDLARRQSGYGRGGRMKIEQDRVQVLS
CCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHH
GIRHGKTLGSPVALLVENRDWLNWTEVMSPAPLEAYTDPRAAQKVRTRPRPGHADLAGAL
HHHCCCCCCCCEEEEEECCCCCCHHHHCCCCCCHHCCCCHHHHHHHCCCCCCCCHHHHHH
KYDHADLRNVLERASARETAARVAAGSLAKQYLAPFGIRVAGYVRSIGPVEAQPPAGLDL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCH
DGIVARAEASPVRCPDPAASARMVEEIDAAKRDGDSLGGVVEVVAAGLPPGLGSHVHWDR
HHHHEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCH
KLDGALGAALLSIQAAKGVEIGDGFLGARRRGSEVHDEIGWSPDRGYFRYTNRAGGLEGG
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHCCCCCCCCCEEECCCCCCCCCC
MTNGMDLVVRVAFKPIATLYKPLRSVEIDTHVEAAAGIERSDVCAVPAAAVIAECVTAFE
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LARFVAEKFGGDSLEEALRNFRGYLEQIARR
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRYLTAGESHGRALVTIVEGLPAGVPVDLAAIDRDLARRQSGYGRGGRMKIEQDRVQVLS
CCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHH
GIRHGKTLGSPVALLVENRDWLNWTEVMSPAPLEAYTDPRAAQKVRTRPRPGHADLAGAL
HHHCCCCCCCCEEEEEECCCCCCHHHHCCCCCCHHCCCCHHHHHHHCCCCCCCCHHHHHH
KYDHADLRNVLERASARETAARVAAGSLAKQYLAPFGIRVAGYVRSIGPVEAQPPAGLDL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCH
DGIVARAEASPVRCPDPAASARMVEEIDAAKRDGDSLGGVVEVVAAGLPPGLGSHVHWDR
HHHHEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCH
KLDGALGAALLSIQAAKGVEIGDGFLGARRRGSEVHDEIGWSPDRGYFRYTNRAGGLEGG
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHCCCCCCCCCEEECCCCCCCCCC
MTNGMDLVVRVAFKPIATLYKPLRSVEIDTHVEAAAGIERSDVCAVPAAAVIAECVTAFE
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LARFVAEKFGGDSLEEALRNFRGYLEQIARR
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA