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The map label for this gene is adcA [H]

Identifier: 51893019

GI number: 51893019

Start: 2021940

End: 2022926

Strand: Reverse

Name: adcA [H]

Synonym: STH1881

Alternate gene names: 51893019

Gene position: 2022926-2021940 (Counterclockwise)

Preceding gene: 51893020

Following gene: 51893018

Centisome position: 56.73

GC content: 70.82

Gene sequence:

>987_bases
GTGGCAGCGGTCACGGCGCTGCTGTTGCTGGCGGGCTGTGCGACGGCCGACGGCGCCCGCAGGGGGGCCTCCGGCTTCGC
GGAGGACGGAAGGCTGCGGGTGGTCGCCAGCATCTATCCGATATACGAGTTTGCGCGGGCGGTGGGCGGAGACCGGATCG
AACTGGTCAACCTGGTCCCGCCGGGCACCGAGCCCCACGACTGGGAACCGTCGGTGGGTGACATCCGCACCCTGAACGGC
GCACAGGTCTTCCTGTACGCGGGCGCGGGCTTCGAGCACTGGATCGACAAGGCGCTCGCCTCGCTGGACAACCGCGACCT
GATCGCCGTGGAGACCAGCGCCGGGTTCGCCCTTCTGGGGGGGAACCCGAGCCACGGTGACGAAAGCGCGCACGACGACC
ACGATGAAGGCCTGCACGGGGATCACCAGGAGGGGGCGGACGAGGGCCACCATCACGGTGGCCTGGATCCCCACATCTGG
CTGGATCCGACCGGCGCCGCCCACATCGTGGAGCGGATCCGCGACGGGCTGGCCGCCGCCGACCCGGGCAACGCGGACGT
GTACCGCACAAGCGCTGCGGCGTACCTGAAGGAGCTGGAGGCGCTGGACCGGGAGTATGCCGCAGGTCTCGCCCAGTGCG
AGCGGCGGACCTTCTTCACCACCCACGCCGCCTTCGGCTACCTGGCCCGCCGCTACGGCCTGGAACAGCGGGCCATCATG
GGGCTGGCCCCGGACGCCGAACCGACCCCGCGGGCCCTGAAGGCGGTCGTGGACGCGGCCCGGGAGCAGGATGTCCGGTA
CATCTTCTTCGAGACGCTGGTGAGCGACAGGGTCGCCCGCGTGGTGGCGGACGAGATCGGCGCCGAGACGCTGGTGCTCA
ACCCCTTCGAGGGGCTGACGCCGGAGCAGGTCGCCGCCGGGGAGGACTACCTGTCGGTCATGCGGGAGAACCTCGCCAAC
CTGCGCATTGCACTGGGGTGCCGGTGA

Upstream 100 bases:

>100_bases
AAGCCAGGGCCAAGTGCAGAATGCCGCAGTGGGGGCGCAGAAGATCCGGTATTCATCGCTGGAGGAGGGCTGCACGAGGA
TGCGCCGACTGAGAGGGTTC

Downstream 100 bases:

>100_bases
TGGTTGCGACGAGTCCGGTCATCGAGGTGCGGAACGTCAGCTTCGGTTACGGTAAGGATCTGGTGCTGGACCGTGTCAGC
CTGACGGTGGGGCGCGGGGA

Product: ABC transporter substrate-binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MAAVTALLLLAGCATADGARRGASGFAEDGRLRVVASIYPIYEFARAVGGDRIELVNLVPPGTEPHDWEPSVGDIRTLNG
AQVFLYAGAGFEHWIDKALASLDNRDLIAVETSAGFALLGGNPSHGDESAHDDHDEGLHGDHQEGADEGHHHGGLDPHIW
LDPTGAAHIVERIRDGLAAADPGNADVYRTSAAAYLKELEALDREYAAGLAQCERRTFFTTHAAFGYLARRYGLEQRAIM
GLAPDAEPTPRALKAVVDAAREQDVRYIFFETLVSDRVARVVADEIGAETLVLNPFEGLTPEQVAAGEDYLSVMRENLAN
LRIALGCR

Sequences:

>Translated_328_residues
MAAVTALLLLAGCATADGARRGASGFAEDGRLRVVASIYPIYEFARAVGGDRIELVNLVPPGTEPHDWEPSVGDIRTLNG
AQVFLYAGAGFEHWIDKALASLDNRDLIAVETSAGFALLGGNPSHGDESAHDDHDEGLHGDHQEGADEGHHHGGLDPHIW
LDPTGAAHIVERIRDGLAAADPGNADVYRTSAAAYLKELEALDREYAAGLAQCERRTFFTTHAAFGYLARRYGLEQRAIM
GLAPDAEPTPRALKAVVDAAREQDVRYIFFETLVSDRVARVVADEIGAETLVLNPFEGLTPEQVAAGEDYLSVMRENLAN
LRIALGCR
>Mature_327_residues
AAVTALLLLAGCATADGARRGASGFAEDGRLRVVASIYPIYEFARAVGGDRIELVNLVPPGTEPHDWEPSVGDIRTLNGA
QVFLYAGAGFEHWIDKALASLDNRDLIAVETSAGFALLGGNPSHGDESAHDDHDEGLHGDHQEGADEGHHHGGLDPHIWL
DPTGAAHIVERIRDGLAAADPGNADVYRTSAAAYLKELEALDREYAAGLAQCERRTFFTTHAAFGYLARRYGLEQRAIMG
LAPDAEPTPRALKAVVDAAREQDVRYIFFETLVSDRVARVVADEIGAETLVLNPFEGLTPEQVAAGEDYLSVMRENLANL
RIALGCR

Specific function: Part of the ATP-driven transport system AdcABC for zinc [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=267, Percent_Identity=25.4681647940075, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR012674
- InterPro:   IPR011038
- InterPro:   IPR006128
- InterPro:   IPR015304 [H]

Pfam domain/function: PF01297 SBP_bac_9; PF09223 YodA [H]

EC number: NA

Molecular weight: Translated: 35259; Mature: 35127

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAVTALLLLAGCATADGARRGASGFAEDGRLRVVASIYPIYEFARAVGGDRIELVNLVP
CHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEEECC
PGTEPHDWEPSVGDIRTLNGAQVFLYAGAGFEHWIDKALASLDNRDLIAVETSAGFALLG
CCCCCCCCCCCCCCEEECCCCEEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCEEEEC
GNPSHGDESAHDDHDEGLHGDHQEGADEGHHHGGLDPHIWLDPTGAAHIVERIRDGLAAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCC
DPGNADVYRTSAAAYLKELEALDREYAAGLAQCERRTFFTTHAAFGYLARRYGLEQRAIM
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHC
GLAPDAEPTPRALKAVVDAAREQDVRYIFFETLVSDRVARVVADEIGAETLVLNPFEGLT
CCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCC
PEQVAAGEDYLSVMRENLANLRIALGCR
HHHHHCCHHHHHHHHHHHHHEEEEECCC
>Mature Secondary Structure 
AAVTALLLLAGCATADGARRGASGFAEDGRLRVVASIYPIYEFARAVGGDRIELVNLVP
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEEECC
PGTEPHDWEPSVGDIRTLNGAQVFLYAGAGFEHWIDKALASLDNRDLIAVETSAGFALLG
CCCCCCCCCCCCCCEEECCCCEEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCEEEEC
GNPSHGDESAHDDHDEGLHGDHQEGADEGHHHGGLDPHIWLDPTGAAHIVERIRDGLAAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCC
DPGNADVYRTSAAAYLKELEALDREYAAGLAQCERRTFFTTHAAFGYLARRYGLEQRAIM
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHC
GLAPDAEPTPRALKAVVDAAREQDVRYIFFETLVSDRVARVVADEIGAETLVLNPFEGLT
CCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCC
PEQVAAGEDYLSVMRENLANLRIALGCR
HHHHHCCHHHHHHHHHHHHHEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]