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The map label for this gene is perR [H]

Identifier: 51893020

GI number: 51893020

Start: 2023031

End: 2023477

Strand: Reverse

Name: perR [H]

Synonym: STH1882

Alternate gene names: 51893020

Gene position: 2023477-2023031 (Counterclockwise)

Preceding gene: 51893021

Following gene: 51893019

Centisome position: 56.74

GC content: 63.98

Gene sequence:

>447_bases
ATGCAGGTGGAGCAGGTTCTGCAGCGACTGAAGGACATGGGCTGCAAGCTGACGCCCCAGCGGCGGCTCATCGTCGAGGT
CCTCCTGAGCGCGGGCGAGGGCGCGCTGACCGCCGATGAGATCTACCAGCAGGTGCGGCAGACCTATCCCGAGATCGGCC
TGGACACCATTTACCGGAACCTGCGGTTGATGGCCCGGCTGAACGTGGTTTCCGAGGTGAAGCTGACAGGGCGGACGGCG
CAGTACTCGCTGAACCGGGAGCTCCACAACCACAGCCTGGTGTGTTTGGAGTGCGGGGCGGAGATCCCCCTGGCGCACTG
CCCCATCAAGGAGCTGGAGGCGGTGGCGCTGGAGCAGCACGGCTTCATCATCTCCGCCCACCGCATCGAGCTGTTCGGCT
ACTGTCCCGCATGCGCACCGGGTGCAGACAATAAAATTCCTACTTGA

Upstream 100 bases:

>100_bases
CGGACCAGGGCGCTGGCCCTGGTCTTCGTGTTGACAGGGGCGGTGCGGGCGGCTAAACTCAAATAGGAATTTTACTGGTT
CGGAGCAGGGAGGGTGCCCC

Downstream 100 bases:

>100_bases
CGGCAAGCCAGGGCCAAGTGCAGAATGCCGCAGTGGGGGCGCAGAAGATCCGGTATTCATCGCTGGAGGAGGGCTGCACG
AGGATGCGCCGACTGAGAGG

Product: Fur family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MQVEQVLQRLKDMGCKLTPQRRLIVEVLLSAGEGALTADEIYQQVRQTYPEIGLDTIYRNLRLMARLNVVSEVKLTGRTA
QYSLNRELHNHSLVCLECGAEIPLAHCPIKELEAVALEQHGFIISAHRIELFGYCPACAPGADNKIPT

Sequences:

>Translated_148_residues
MQVEQVLQRLKDMGCKLTPQRRLIVEVLLSAGEGALTADEIYQQVRQTYPEIGLDTIYRNLRLMARLNVVSEVKLTGRTA
QYSLNRELHNHSLVCLECGAEIPLAHCPIKELEAVALEQHGFIISAHRIELFGYCPACAPGADNKIPT
>Mature_148_residues
MQVEQVLQRLKDMGCKLTPQRRLIVEVLLSAGEGALTADEIYQQVRQTYPEIGLDTIYRNLRLMARLNVVSEVKLTGRTA
QYSLNRELHNHSLVCLECGAEIPLAHCPIKELEAVALEQHGFIISAHRIELFGYCPACAPGADNKIPT

Specific function: Manganese-dependent repressor that controls a regulon of oxidative stress resistance and iron-storage proteins. May act as a hydrogen peroxide and organic hydroperoxide sensor [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=127, Percent_Identity=29.1338582677165, Blast_Score=67, Evalue=3e-13,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16538; Mature: 16538

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVEQVLQRLKDMGCKLTPQRRLIVEVLLSAGEGALTADEIYQQVRQTYPEIGLDTIYRN
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHH
LRLMARLNVVSEVKLTGRTAQYSLNRELHNHSLVCLECGAEIPLAHCPIKELEAVALEQH
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCC
GFIISAHRIELFGYCPACAPGADNKIPT
CEEEEEEEEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MQVEQVLQRLKDMGCKLTPQRRLIVEVLLSAGEGALTADEIYQQVRQTYPEIGLDTIYRN
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHH
LRLMARLNVVSEVKLTGRTAQYSLNRELHNHSLVCLECGAEIPLAHCPIKELEAVALEQH
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCC
GFIISAHRIELFGYCPACAPGADNKIPT
CEEEEEEEEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA